NCT03060330

Laparoscopic Ventral Mesh Rectopexy Combined With or Without Stapled Trans-anal Rectal Resection for Obstructed Defecation Syndrome

Obstructed Defecation Caused by Rectal Prolapse and Rectocele: Laparoscopic Ventral Rectopexy Alone Versus Laparoscopic Ventral Rectopexy Combined With Stapled Trans-anal Rectal Resection

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 126 (estimated)
• Sponsor: Renmin Hospital of Wuhan University · Academic / Other
• Sex: Female
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Obstructed defecation syndrome (ODS) is a common problem in women. Rectal prolapse and rectocoele are frequently identified in patients with ODS. Surgery is the only definite treatment for those patients and is preferably performed minimally invasive. The most used procedures are laparoscopic ventral mesh rectopexy (LVMR) and stapled trans-anal rectal resection (STARR). However, high-level prospective studies on treatment strategies for ODS currently are lacking and, thus, no consensus exist regarding the optimal treatment for patients with ODS. This study aimed to compare LVMR alone and LVMR combined with STARR evaluating functional and anatomical results.

Conditions

• Obstructive Defecation Syndrome
• Chronic Constipation
• Rectal Prolapse

Interventions

Type	Name	Description
PROCEDURE	Modified Laparoscopic Ventral Mesh Rectopexy	This group will undergo modified laparoscopic ventral mesh rectopexy alone
PROCEDURE	Modified Laparoscopic Ventral Mesh Rectopexy Combined with Stapled Trans-anal Rectal Resection	This group will undergo modified laparoscopic ventral mesh rectopexy combined with modified stapled trans-anal rectal resection

Timeline

• Start date: 2017-04-26
• Primary completion: 2025-04-01
• Completion: 2026-04-01
• First posted: 2017-02-23
• Last updated: 2022-03-15

Locations

1 site across 1 country: China