Clinical Trials Directory

Trials / Completed

CompletedNCT00545103

Prevention of Recurrence of Diverticulitis

A Phase III, Randomised, Double-Blind, Dose-Response, Stratified, Placebo-Controlled Study Evaluating the Safety and Efficacy of SPD476 Versus Placebo Over 104 Weeks in the Prevention of Recurrence of Diverticulitis.

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
592 (actual)
Sponsor
Shire · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine whether SPD476 is effective in reducing recurrence of diverticulitis.

Conditions

Interventions

TypeNameDescription
DRUGSPD476, MMX™ mesalazine, 1.2g extended release tabletSPD476 1.2g administered Once Daily (QD)
DRUGSPD476, MMX™ mesalazine, 2.4g extended release tabletSPD476 2.4g administered Once Daily (QD)
DRUGSPD476, MMX™ mesalazine, 4.8g extended release tabletSPD476 4.8g administered Once Daily (QD)
DRUGPlaceboPlacebo administered Once Daily (QD)

Timeline

Start date
2007-12-06
Primary completion
2011-11-28
Completion
2011-11-28
First posted
2007-10-17
Last updated
2021-06-11
Results posted
2012-12-19

Locations

131 sites across 10 countries: United States, Brazil, Canada, Finland, Germany, Hungary, Italy, Netherlands, Romania, South Africa

Source: ClinicalTrials.gov record NCT00545103. Inclusion in this directory is not an endorsement.