Clinical Trials Directory

Trials / Completed

CompletedNCT03336450

Study of Midazolam Hydrochloride Oromucosal Solution (MHOS/SHP615) in Pediatric Patients With Status Epilepticus (Convulsive) in the Community Setting

A Phase 3, Multicenter, Open-label Extension Study of Buccally Administered MHOS/SHP615 in Pediatric Patients With Status Epilepticus (Convulsive) in Community Settings

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
3 (actual)
Sponsor
Shire · Industry
Sex
All
Age
6 Months – 216 Months
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine if the investigational treatment, MHOS/SHP615, is safe and effective in children with status epilepticus (SE) (convulsive) in the community setting. This study is open-label extension for patients who completed the SHP615-301 study and who tolerated and responded to MHOS/SHP615 treatment in the hospital setting.

Conditions

Interventions

TypeNameDescription
DRUGSHP615SHP615 oromucosal solution will be administered as a single age-specific dose (2.5, 5, 7.5 and 10 mg).
DRUGMHOS/SHP615MHOS/SHP615

Timeline

Start date
2018-04-23
Primary completion
2020-10-13
Completion
2020-10-13
First posted
2017-11-08
Last updated
2021-09-14
Results posted
2021-09-14

Locations

23 sites across 1 country: Japan

Source: ClinicalTrials.gov record NCT03336450. Inclusion in this directory is not an endorsement.

Study of Midazolam Hydrochloride Oromucosal Solution (MHOS/SHP615) in Pediatric Patients With Status Epilepticus (Convul (NCT03336450) · Clinical Trials Directory