Clinical Trials Directory

Trials / Completed

CompletedNCT00567502

Safety and Pregnancy Outcomes in Thrombocythemia Patients Exposed to XAGRID® (Anagrelide Hydrochloride) Compared to Other Treatments

A Non-Interventional, Post Authorisation Safety Study, to Continuously Monitor Safety and Pregnancy Outcomes in a Cohort of At-Risk Essential Thrombocythaemia (ET) Subjects Exposed to Xagrid Compared to Other Conventional Cytoreductive Treatments

Status
Completed
Phase
Study type
Observational
Enrollment
3,647 (actual)
Sponsor
Shire · Industry
Sex
All
Age
Healthy volunteers
Not accepted

Summary

This is an observational safety study being conducted in Europe comparing patients taking Xagrid to patients taking other cytoreductive treatments. The plan is to enrol at least 750 subjects taking Xagrid with up to 3000 subjects taking other cytoreductive therapies. The study will collect follow up data for 5 years for each patient enrolled that will focus on collecting data related to pre-defined events (PDEs) and Suspected Serious Adverse Reactions (SSARs).

Conditions

Timeline

Start date
2005-05-31
Primary completion
2014-04-30
Completion
2014-04-30
First posted
2007-12-05
Last updated
2021-06-09
Results posted
2015-11-17

Locations

164 sites across 14 countries: Cyprus, Denmark, Finland, France, Germany, Greece, Ireland, Italy, Netherlands, Norway, Portugal, Spain, Sweden, United Kingdom

Source: ClinicalTrials.gov record NCT00567502. Inclusion in this directory is not an endorsement.

Safety and Pregnancy Outcomes in Thrombocythemia Patients Exposed to XAGRID® (Anagrelide Hydrochloride) Compared to Othe (NCT00567502) · Clinical Trials Directory