Trials / Completed
CompletedNCT01515865
Clinical Efficacy of Midodrine in Symptomatic Orthostatic Hypotension
A Phase 4, Randomized-withdrawal, Double-blind, Placebo Controlled, Parallel-group Study to Investigate the Clinical Benefit of Midodrine Hydrochloride in Male and Female Subjects With Symptomatic Orthostatic Hypotension
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 98 (actual)
- Sponsor
- Shire · Industry
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
To study the effect of midodrine against the symptoms of orthostatic hypotension
Detailed description
The efficacy of midodrine will be assessed in those subjects who have severe symptoms of orthostatic hypotension when not taking midodrine and are controlled when taking midodrine. The study will involve approximately 9 overnight stays.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Midodrine HCl | dose at subject's current dose level |
| DRUG | Placebo | single dose of matching placebo |
Timeline
- Start date
- 2012-05-23
- Primary completion
- 2013-11-11
- Completion
- 2013-11-11
- First posted
- 2012-01-24
- Last updated
- 2021-06-09
- Results posted
- 2014-10-22
Locations
32 sites across 4 countries: United States, Czechia, Poland, Slovakia
Source: ClinicalTrials.gov record NCT01515865. Inclusion in this directory is not an endorsement.