Trials / Completed
CompletedNCT01518946
Tilt-Table Study of the Clinical Efficacy of Midodrine in Symptomatic Orthostatic Hypotension
A Phase 4, Randomized, Double-blind, Placebo-controlled, Crossover Study to Investigate the Clinical Benefit of Midodrine Hydrochloride in Male and Female Subjects With Symptomatic Orthostatic Hypotension
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 24 (actual)
- Sponsor
- Shire · Industry
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to determine whether midodrine works against the symptoms of orthostatic hypotension caused by being on a tilt table.
Detailed description
The efficacy of midodrine will be assessed in those subjects who have severe symptoms of orthostatic hypotension when not taking midodrine and are controlled when taking midodrine. The study will involve approximately 4 overnight stays.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Midodrine HCl | dose at the subject's current dose level |
| DRUG | Placebo | single dose of matching placebo |
Timeline
- Start date
- 2012-05-14
- Primary completion
- 2013-06-22
- Completion
- 2013-06-22
- First posted
- 2012-01-26
- Last updated
- 2021-06-08
- Results posted
- 2014-07-31
Locations
13 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT01518946. Inclusion in this directory is not an endorsement.