| Recruiting | Fish Oil, Metformin and Heart Health in PCOS NCT06424860 | University of Alberta | Phase 1 |
| Recruiting | PIMS vs PGT-A in Infertile PCOS Patients NCT06887881 | First Affiliated Hospital, Sun Yat-Sen University | N/A |
| Recruiting | Liraglutide Treatment in Obese Infertile PCOS Women NCT06742710 | Peking University Third Hospital | Phase 4 |
| Recruiting | Cabergoline & Letrozole Versus Letrozole in Ovulation Induction in PCOS NCT07255911 | Mst.Sumyara Khatun | N/A |
| Recruiting | Adipokines in Polycystic Ovary Syndrome NCT06793072 | Jagiellonian University | — |
| Recruiting | Exogenous Ketone Supplementation in Females with Polycystic Ovary Syndrome NCT06155708 | McGill University | N/A |
| Completed | Myoinositol vs. Metformin for Polycystic Ovarian Syndrome (PCOS): Impact on Metabolic Health and Fertility NCT07058675 | Benha University | N/A |
| Enrolling By Invitation | Study of Time-restricted Eating (TRE) to Clinical Pregnancy Rate in PCOS Women With Glucose Metabolism Disorde NCT06666933 | RenJi Hospital | N/A |
| Completed | Pretreatment With CPA-EE, Metformin and Myoinositol in PCOS With High AMH NCT07513480 | Mst.Sumyara Khatun | N/A |
| Completed | Comparing the Effect of Metformin vs. Pep2dia as an Adjunct to Letrozole on Ovulation Induction and Pregnancy NCT06452511 | Muhamed Ahmed Abdelmoaty Muhamed Alhagrasy | EARLY_Phase 1 |
| Recruiting | Lifestyle Changes in PCOS with OSA and NAFLD NCT06591169 | Cairo University | N/A |
| Completed | Diagnostics of Clinical Hyperandrogenism NCT06530498 | Jagiellonian University | — |
| Recruiting | Bicalutamide Therapy in Young Women With NAFLD and PCOS NCT05979389 | University of California, San Francisco | Phase 1 |
| Recruiting | Cardiovascular and Endothelial Markers During OGTT Before and at Six and Twelve Months Post-treatment in Women NCT06889454 | Attikon Hospital | — |
| Recruiting | Androgens and NAFLD Longitudinal Cohort Study NCT06124261 | University of California, San Francisco | — |
| Recruiting | Effects of Sprint Interval Training Versus Arabic Exercises BMI NCT06461585 | Riphah International University | N/A |
| Recruiting | Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for PCOS NCT06143527 | The Foundation for Orthopaedics and Regenerative Medicine | Phase 1 |
| Completed | Dampening the Reproductive Axis With Continuous Kisspeptin NCT05971849 | Stephanie B. Seminara, MD | Phase 1 |
| Completed | Effect of Vitamin D Supplementation on Testosterone Level in Women With Polycystic Ovary Syndrome NCT06101147 | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | Phase 2 |
| Unknown | Neuropeptide Expression During the Ovarian Cycle and in Patients With PCOS NCT05958914 | University Of Perugia | N/A |
| Unknown | The Living With a Long-Term Condition Study NCT06072287 | King's College London | — |
| Completed | Exogenous Ketone Ester in Women with Polycystic Ovary Syndrome. NCT05762822 | University of Aarhus | N/A |
| Completed | Anxiety Disorders, Depression and Related Factors in PCOS NCT05864690 | Mỹ Đức Hospital | — |
| Completed | Endocrine, Metabolic and Inflammatory Characteristics of Offspring of Mothers With PCOS Hyperandrogenism NCT06371313 | Guangdong Women and Children Hospital | — |
| Recruiting | In Vitro Maturation of Human Eggs NCT06633120 | Colorado Center for Reproductive Medicine | N/A |
| Completed | Efficacy and Safety of Dingkundan Combined With Combination Oral Contraceptives in the Treatment of PCOS NCT05872425 | Guangdong Women and Children Hospital | N/A |
| Completed | Effect of Web-Based Module on Nursing Students' Knowledge, Practice and Attitude Regarding Polycystic Ovary Sy NCT06192381 | Safa Hamdy Alkalash Alsayed | N/A |
| Completed | Independent and Additive Effects Of Micronutrients With Metformin In Patients With PCOS NCT05653895 | Khyber Medical University Peshawar | N/A |
| Unknown | Androgen Blockade and Progesterone Augmentation of Gonadotropin Secretion NCT04597099 | University of Virginia | EARLY_Phase 1 |
| Unknown | The Angiotensin-Melatonin Axis in Poor and Hyper Responders for IVF Treatment NCT05298657 | Fatima College of Health Sciences | — |
| Completed | Effect of 'Cramp Bites' on Period Cramps in Women Aged 18-25 NCT06227676 | Cornell University | Phase 2 / Phase 3 |
| Completed | Myo-inositol Plus Alpha-lactalbumin in PCOS Myo-inositol-resistant Patients NCT03667443 | Lo.Li.Pharma s.r.l | N/A |
| Unknown | The Effect of Pretreatment With Dydrogesterone Vs Combined Estradiol Valerate and Dydrogestrone on Clinical Pr NCT05300841 | Sohag University | EARLY_Phase 1 |
| Unknown | Live Birth After Letrozole-stimulated Cycles Versus Hormone Replacement Treatment Cycles for the First Frozen NCT05227391 | Reproductive & Genetic Hospital of CITIC-Xiangya | N/A |
| Unknown | Sexual Dysfunction in Infertile Women With PCOS Undergoing Fertility Treatment NCT05402800 | Cairo University | — |
| Completed | Effect of EE/NETA With Scaling on Periodontium and hsCRP in PCOS Women With Gingivitis NCT05129878 | Postgraduate Institute of Dental Sciences Rohtak | N/A |
| Terminated | A Pilot Study to Determine the Feasibility, Acceptance, and Effectiveness of In-vitro Maturation in Patients W NCT05793931 | Northwestern University | — |
| Completed | Myoinositol Treatment and Asprosin Levels in PCOS NCT05951309 | Near East University, Turkey | N/A |
| Unknown | Effect of Acupuncture Plus Governor Vessel Moxibustion Combined With Letrozole on Live Birth in Anovulatory In NCT04987632 | Qiu-ping Lin | Phase 1 |
| Completed | Progesterone-Primed Ovarian Simulation in Controlled-ovarian Simulation of Infertile PCOS Patients NCT05939284 | Zagazig University | N/A |
| Unknown | Time-restricted Eating to Improve Metabolic Abnormalities in Polycystic Ovarian Syndrome NCT05126199 | Ruairí Floyd | N/A |
| Completed | Effects of Combined Resveratrol and Myo-inositol on Altered Metabolic, Endocrine Parameters and Perceived Stre NCT04867252 | Khyber Medical University Peshawar | Phase 2 |
| Unknown | Effect of GM-CSF on CAPA-IVM System Success Rates in PCOS NCT04774432 | Mỹ Đức Hospital | N/A |
| Completed | Ketogenic Diet in PCOS With Obesity and Insulin Resistance NCT04801173 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | N/A |
| Completed | The Effect of Polycystic Ovary Syndrome on the Embryo Morphokinetics ( PCOS ) NCT05438355 | ShangHai Ji Ai Genetics & IVF Institute | — |
| Unknown | Comparison of Myoinositol and Metformin in PCO NCT04204044 | Rashid Latif Medical College | EARLY_Phase 1 |
| Active Not Recruiting | Randomized Controlled Trial of Combined Letrozole and Clomid (CLC II) Versus Letrozole Alone for Women With An NCT05206448 | Rachel Mejia | Phase 4 |
| Completed | Single vs. Group CAPA-IVM Culture of Cumulus-oocyte Complexes NCT04562883 | Mỹ Đức Hospital | N/A |
| Completed | Glucose Metabolism and Live Birth Outcomes in PCOS NCT04364087 | Mỹ Đức Hospital | — |
| Completed | Fresh Versus Freeze-only After CAPA IVM on PCOS Patients NCT04297553 | Mỹ Đức Hospital | N/A |
| Active Not Recruiting | Transcriptional and Epigenetic Program of PCOS Women NCT04034706 | AdventHealth Translational Research Institute | — |
| Completed | The Effect of Astaxanthin on Oxidative Stress Indices in Patients With Polycystic Ovary Syndrome NCT03991286 | Tehran University of Medical Sciences | N/A |
| Completed | Effects of Acupuncture on Body Mass Index in Overweight and Obese Women With Polycystic Ovary Syndrome (PCOS ) NCT04193371 | Peking University Third Hospital | N/A |
| Completed | Changes in Hormonal Profile and Body Mass Index in Women With Polycystic Ovary Syndrome After Probiotic Intake NCT06761625 | Pomeranian Medical University Szczecin | N/A |
| Completed | The Effects of Semaglutide on Taste, Tongue Tissue Transcriptome, Gastric Emptying and Central Neural Response NCT04263415 | University Medical Centre Ljubljana | Phase 4 |
| Completed | Effects of Triple Drug Cocktail Therapy on Metabolic, Endocrine Alterations and Perceived Stress in Patients W NCT04113889 | Khyber Medical University Peshawar | Phase 2 |
| Unknown | The Effect of Ibuprofen on Women With PCOS. NCT04485403 | Poznan University of Medical Sciences | Phase 2 |
| Unknown | Pomegranate Juice Effect on Oxidative Stress in Infertile Women During IVF Treatment NCT03978013 | Rambam Health Care Campus | N/A |
| Completed | Treating PCOS With Semaglutide vs Active Lifestyle Intervention NCT03919929 | University of Colorado, Denver | Phase 2 / Phase 3 |
| Unknown | Role of Nesfatin-1 and Nicotinamide in Infertile Women With Polycystic Ovary Syndrome NCT03870035 | Assiut University | — |
| Completed | Amphiregulin Versus Non-Amphiregulin Supplementation to Maturation Culturing Medium in IVM. NCT03915054 | Mỹ Đức Hospital | N/A |
| Completed | Vitamin D Supplementation in PCOS Patients NCT03898934 | Tanta University | Phase 4 |
| Completed | A Treatment Legacy Effect of Metformin in Obese Women With PCOS NCT04566718 | University Medical Centre Ljubljana | — |
| Completed | The Gut Microbiome in Women With Polycystic Ovary Syndrome NCT03642600 | Universitaire Ziekenhuizen KU Leuven | Phase 4 |
| Completed | Bisphenol Role in the Pathogenesis of PCOS NCT03436108 | Aljazeera Hospital | — |
| Completed | Office Hysteroscopy in Infertility Work-out: the Role of Endometrial Hyperplasia in Southern Italian Women NCT03965585 | University of Campania Luigi Vanvitelli | — |
| Unknown | Myo-inositol as Pretreatment in Hyperandrogenic PCOS Patients NCT03767569 | Universitair Ziekenhuis Brussel | Phase 3 |
| Completed | Low Starch Dietary Education Program vs. Traditional Treatment for PCOS NCT03916263 | Texas Tech University Health Sciences Center | EARLY_Phase 1 |
| Completed | An Integrated Self-Management Intervention for Adolescents With Polycystic Ovary Syndrome NCT03600337 | University of Texas at Austin | N/A |
| Completed | Effect of Chromium Supplementation on Intracytoplasmatic Sperm Injection (ICSI) Outcomes in Polycystic Ovary S NCT03503201 | Kasr El Aini Hospital | N/A |
| Completed | Vitamin D for Polycystic Ovary Syndrome Clomiphene Resistant Women NCT04010942 | Ain Shams University | Phase 4 |
| Unknown | IVM Versus Standard IVF in Infertile Patients Diagnosed With PCOS NCT03463772 | Jie Qiao | N/A |
| Unknown | Effect of Laparoscopic Ovarian Drilling on Outcomes of in Vitro Fertilisation in Clomiphene-resistant Women Wi NCT03527979 | Ain Shams University | N/A |
| Completed | In Vitro Fertilization Impact on Metabolic Parameters NCT03426228 | University of Warwick | — |
| Completed | IVM Versus IVF in High Antral Follicle Count Patients NCT03405701 | Mỹ Đức Hospital | N/A |
| Unknown | Androgen Responses to hCG and Ovarian Morphology in PCOS NCT03489668 | Poznan University of Medical Sciences | N/A |
| Completed | Comparing the Effects of Oral Contraceptive Pills Versus Metformin NCT03229057 | Anuja Dokras | Phase 3 |
| Completed | Assessment of Endometrial Thickness & Subendometrial Perfusion by 3D Power Doppler in Women With Unexplained I NCT03397693 | Assiut University | — |
| Unknown | Research of Intensive Metabolic Intervention Before Pregnancy in PCOS NCT03383068 | RenJi Hospital | Phase 4 |
| Terminated | Metformin, Vitamin D, and Depression in Polycystic Ovary Syndrome (PCOS) Trial NCT03380091 | University of California, San Francisco | Phase 4 |
| Terminated | The Mechanism of Modified Utral-long Protocol in Improving Endometrial Receptivity in Patients With PCOS and I NCT03100240 | Reproductive & Genetic Hospital of CITIC-Xiangya | N/A |
| Completed | OCP vs Metformin on Ovarian Stromal Blood Flow in PCOS NCT03236740 | S.C.B. Medical College and Hospital | Phase 4 |
| Unknown | Effect of Dietary Modifacation on Microbiota in Overweight and Obese Polycystic Ovary Syndrome Patients NCT03325023 | Poznan University of Medical Sciences | Phase 4 |
| Completed | N-Acetylcysteine and L-carnitine in Pcos NCT03164421 | Zagazig University | Phase 2 |
| Completed | L-carnitine and Metformin in Obese PCOS Women. NCT03108963 | Zagazig University | Phase 2 |
| Unknown | A Metabolomic Study of Polycystic Ovary Syndrome With Insulin Resistance and Its Relationship With TCM Syndrom NCT02992093 | Fujian Maternity and Child Health Hospital | — |
| Unknown | A Clinical and Biological Research of Combined Chinese and Western Medicine in the Treatment of PCOS NCT03264638 | Aijun Sun | Phase 2 |
| Completed | Myo-inositol, D-chiro-inositol and Glucomannan in PCOS NCT03608813 | University of Salerno | — |
| Completed | Sitagliptin Improved Beta Cell Function and Prevented a Conversion Rate to Impaired Glucose Tolerance and Type NCT03122041 | University Medical Centre Ljubljana | Phase 4 |
| Completed | Metabolic and Neuro-Endocrine Effect of Treating PCOS in Adolescents NCT03981861 | Children's Mercy Hospital Kansas City | Phase 2 / Phase 3 |
| Unknown | Ultrasound Three-dimensional Characterization of Ovarian Morphology in Women With Polycystic Ovary Syndrome (P NCT02402413 | University of Cagliari | N/A |
| Completed | Eastern Siberia PCOS Epidemiology & Phenotype Study NCT05194384 | Federal State Public Scientific Institution, Scientific Center for Family Health and Human Reproduction Problems | — |
| Completed | Correction of Vitamin D Deficiency and Its Effect on Ovulation Induction in Women With PCOS (VIDEO): A Feasibi NCT02656121 | Ain Shams University | Phase 2 |
| Terminated | The SNORES Randomized Clinical Trial NCT02442999 | University of South Florida | N/A |
| Completed | Non-alcoholic Fatty Liver Disease in Women With Polycystic Ovary Syndrome NCT05843955 | Hacettepe University | — |
| Completed | Ultrasonographic Evaluation of Anovulatory Disorders in Lean and Overweight Women NCT03306849 | Cornell University | — |
| Completed | Clomiphene Citrate Versus Tamoxifen for Ovulation Induction in PCOs NCT02479256 | Ain Shams University | Phase 4 |
| Completed | Furocyst - Poly Cystic Ovary Syndrome Study NCT02703064 | Chemical Resources | N/A |
| Completed | DUS on the Prescribing Indications for CPA/EE in 5 European Countries NCT02494297 | Center for Epidemiology and Health Research, Germany | — |
| Unknown | Effect of Bromocriptine on Insulin Resistance in Polycystic Ovarian Syndrome - A Pilot Study NCT02133755 | IWK Health Centre | Phase 3 |
| Completed | Short Term Weight Loss With Liraglutide and Metformin in Infertile Obese PCOS Patients NCT03034941 | University Medical Centre Ljubljana | Phase 4 |
| Completed | PDE-4 Inhibitor Roflumilast and GLP-1 Agonist Liraglutide in Polycystic Ovary Syndrome NCT02187250 | University Medical Centre Ljubljana | Phase 4 |
| Terminated | Insulin Differences Between African-American and Caucasian Female Adolescents With Polycystic Ovary Syndrome ( NCT02052479 | Nationwide Children's Hospital | N/A |
| Completed | Role of Myo-inositol and D-chiro Inositol on the Ovaric and Metabolic Functions NCT01626443 | Lo.Li.Pharma s.r.l | Phase 4 |
| Completed | Liraglutide as Add on Therapy on Metformin in Women With Polycystic Ovary Syndrome NCT02483299 | University Medical Centre Ljubljana | Phase 4 |
| Unknown | Luteal Phase Versus Follicular Phase Administration of Clomiphene Citrate in PCOS, A Randomized Controlled Tri NCT02024984 | Ain Shams Maternity Hospital | Phase 1 |
| Unknown | Prediction of High Ovarian Response After Assisted Reproductive Techniques NCT02358421 | Instituto de Investigacion Sanitaria La Fe | — |
| Completed | PDE-4 Inhibitor Roflumilast and Polycystic Ovary Syndrome NCT02037672 | University Medical Centre Ljubljana | Phase 4 |
| Unknown | Metformin in Step-down Regimen Versus Conventional Low Dose Step-up Protocol in Patients With PCOS Undergoing NCT01438190 | University of Modena and Reggio Emilia | Phase 4 |
| Completed | Eye Evaluation in Patients With PCOS NCT01950832 | Gökhan Açmaz | — |
| Unknown | Vaginal Administration of Metformin in PCOS Patients. NCT02026869 | Assiut University | EARLY_Phase 1 |
| Completed | Use of Degarelix in Controlled Ovarian Hyperstimulation (COH) Protocol for Women With PoliCystic Ovarian Syndr NCT01709942 | Centre for Endocrinology and Reproductive Medicine, Italy | Phase 3 |
| Unknown | PCOS, Therapy and Markers of Cardiovascular Risk NCT01798875 | Medical University of Gdansk | Phase 4 |
| Recruiting | Offspring Born to Mothers With Polycystic Ovary Syndrome in Guangzhou Cohort Study NCT03742011 | Guangzhou Women and Children's Medical Center | — |
| Completed | Polycystic Ovary Syndrome and Liraglutide as Add-on Therapy on Metformin NCT01911468 | University Medical Centre Ljubljana | Phase 4 |
| Completed | Trial Comparing hCG Triggering Versus GnRH Agonist Triggering in PCOS Patients NCT01683513 | AZ Jan Palfijn Gent | Phase 4 |
| Completed | Polycystic Ovary Syndrome and Liraglutide NCT01899430 | University Medical Centre Ljubljana | Phase 4 |
| Completed | Theca Cell Function in Adolescents With Polycystic Ovary Syndrome (PCOS) NCT01154192 | University of California, San Diego | Phase 3 |
| Completed | Cavitation Ultrasound in Treatment of Patients With PCOS NCT01622257 | Ain Shams University | Phase 2 |
| Completed | Effect of Acupuncture on Anti Mullerian Hormone and Assisted Reproduction Outcome in PCOS Patients Undergoing NCT01778621 | Amina Altutunji | N/A |
| Completed | Clomiphene Plus N-acetyl Cysteine for Induction of Ovulation in Newly Diagnosed Pcos. NCT01896492 | Woman's Health University Hospital, Egypt | Phase 4 |
| Terminated | Myoinositol for the Treatment of Ovarian and Psychiatric Disorder in Polycystic Ovary Syndrome (PCOS) Patients NCT01246310 | AGUNCO Obstetrics and Gynecology Centre | N/A |
| Unknown | A Novel Stimulation Protocol and the Conventional Low Dose Step-up and Step Down Regimens NCT01112111 | Genesis Center for Fertility & Human Pre-Implantation Genetics | — |
| Completed | High Plasma Level of Long Pentraxin 3 is Associated With Insulin Resistance in Women With Polycystic Ovary Syn NCT01463969 | Gulhane School of Medicine | — |
| Completed | Unilateral Laparoscopic Diathermy Adjusted to Ovarian Volume NCT01833949 | KBC Split | N/A |
| Completed | Kisspeptin Administration in the Adult NCT00914823 | Massachusetts General Hospital | Phase 1 |
| Terminated | Metformin in Patients With PCOS and Predictors of Poor Ovarian Response Ongoing In-vitro Fertilization NCT01208740 | University Magna Graecia | Phase 4 |
| Completed | Genetics of Polycystic Ovary Syndrome NCT00647335 | University of Pennsylvania | — |
| Terminated | Pilot Study:Role of Dietary Fiber in PCOS Anovulation NCT00703092 | Virginia Commonwealth University | Phase 4 |
| Completed | Determining How Quickly Progesterone Slows LH Pulse Frequency NCT00594217 | University of Virginia | Phase 1 |
| Terminated | Combination Metformin and Oral Contraception for Polycystic Ovary Syndrome (PCOS) NCT00682890 | Virginia Commonwealth University | Phase 4 |
| Completed | Insulin and Polycystic Ovary Syndrome NCT00683774 | Virginia Commonwealth University | N/A |
| Unknown | Database Study on Patients With PCOS NCT01338519 | Odense University Hospital | — |
| Completed | Clinical, Metabolic and Endocrine Effects of the Treatment With Drospirenone and Ethinyl Estradiol Alone or in NCT01511822 | AGUNCO Obstetrics and Gynecology Centre | Phase 4 |
| Completed | Myo-inositol Versus D-chiro-inositol in the Treatment of Polycystic Ovary Syndrome and Insulin Resistance: Eva NCT01514942 | AGUNCO Obstetrics and Gynecology Centre | Phase 4 |