Trials / Recruiting
RecruitingNCT06633120
In Vitro Maturation of Human Eggs
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- Sponsor
- Colorado Center for Reproductive Medicine · Academic / Other
- Sex
- Female
- Age
- 38 Years
- Healthy volunteers
- Not accepted
Summary
CCRM Fertility, a global pioneer in fertility treatment, research and science, is seeking participants for a new study on in vitro maturation (IVM). IVM requires less hormones to stimulate the ovaries than IVF, making it more affordable than IVF with fewer side effects. Participants that qualify for the study will receive a free cycle of IVM treatment at CCRM Fertility and including a new patient consultation, fertility testing, preimplantation genetic testing for aneuploidies (PGT-A), anesthesia and some medication
Detailed description
Patients will undergo a complete IVF workup to qualify for study. Once passing their baseline appointment patients will undergo a three day low dose stimulation followed by egg retrieval 18-22 hours post last medication dosage. Immature oocytes will be retrieved from the ovaries via ultrasound guided TV aspiration and matured overnight in the laboratory. Mature oocytes will be fertilized via ICSI the following day and cultured to the blastocyst stage. Biopsy of the first 14 blastocysts are included with this package, patients have the option biopsy additional embryos if available. Biopsies will be sent for PGTA testing. This study also includes preparation for and the first frozen embryo transfer. Some FET medication is included as well as testing through the first pregnancy test.
Conditions
- Healthy
- PCOS
- PCOS (Polycystic Ovary Syndrome)
- Ovarian Reserve
- Infertility
- Infertility Female
- Infertility of Tubal Origin
- Infertility Poly Cystic Ovary
- AMH
- In Vitro Maturation
- IVM
- IVF
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | IVM | Immature oocytes will be retrieved from small ovarian follicles and matured overnight in the laboratory prior to undergoing fertilization and embryo culture. |
Timeline
- Start date
- 2023-02-03
- Primary completion
- 2029-07-31
- Completion
- 2030-08-30
- First posted
- 2024-10-09
- Last updated
- 2024-10-09
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT06633120. Inclusion in this directory is not an endorsement.