NCT06530498

Diagnostics of Clinical Hyperandrogenism

Diagnostics of Clinical Hyperandrogenism Using the Modified Ferriman-Gallwey Scale and the Ludwig Scale in Women With Normogonadotropic Anovulation

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,330 (actual)
• Sponsor: Jagiellonian University · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: —

Summary

The optimal cut-off value for diagnosing hirsutism in the modified Ferriman-Gallwey (mFG) point scale in the Polish population is not known. The correlation of mFG with the severity of androgenetic alopecia in the Ludwig scale (LS) is not known. The aim of the study is to determine the cut-off point for the diagnosis of hirsutism and to assess the correlation of the mFG scale score with the LS of androgenetic alopecia severity.

Detailed description

The aim of the study is to: * determine the cut-off point on the mFG scale, indicating hirsutism and to determine the correlation of the severity of androgenetic alopecia on the Ludwig scale with the mFG value in the population of women diagnosed and treated at the University Hospital in Krakow due to anovulation. * to determine the severity of hirsutism and the severity of androgenetic alopecia in individual PCOS phenotypes. Inclusion criteria are as follows: i) oligoovulation, i.e. menstrual cycles every \<21 days or \>35 days, ii) age 18-45 years Exclusion criteria: none To achieve the study objectives, the following will be performed: * Visual assessment of the severity of hirsutism on the modified Ferriman-Gallwey scale * Visual assessment of the severity of androgenetic alopecia on the Ludwig scale.

Conditions

• Anovulation
• PCOS

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Assessment of the severity of hirsutism using the visual modified Ferriman-Gallwey scale	Assessment of the severity of hirsutism using the visual modified Ferriman-Gallwey scale in 9 body regions rated from 0 (no growth of terminal hair) to 4 (extensive hair growth), thus with a score ranging from 0 (the lowest score - no hirsutism) to 36 points (the highest score - the greatest severity of hirsutism)
DIAGNOSTIC_TEST	Assessment of the severity of endogenetic alopecia using the visual Ludwig Scale	Visual assessment of baldness on the Ludwig scale from I (least severe baldness) to III (most severe baldness): Type I - minimal thinning of the mid-line parting in the hair; Type II - gradual thinning and noticeable widening of the mid-line parting in the hair; Type III - Heavy to total thinning of the mid-line

Timeline

• Start date: 2024-02-29
• Primary completion: 2025-06-30
• Completion: 2025-10-30
• First posted: 2024-07-31
• Last updated: 2026-04-02

Locations

1 site across 1 country: Poland