NCT02656121

Correction of Vitamin D Deficiency and Its Effect on Ovulation Induction in Women With PCOS (VIDEO): A Feasibility RCT

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 300 (actual)
• Sponsor: Ain Shams University · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

Recently, a special emphasis has recently been directed to the potential role of vitamin D and some regulatory peptides (e.g. adipokines and follistatin) and their associated metabolic roles and genetic factors in the development of PCOS and its related co-morbidities. The aim of this study was to assess the feasibility of conducting a pragmatic RCT assessing the effectiveness of adopting a protocol of screening for and correcting Vitamin D deficiency in women with PCOS seeking fertility treatment in a low/middle income care (LMIC) setting

Detailed description

Research question: In PCOS patients, is there any effect of vitamin D testing and correction on ovulation induction in women with PCOS? Research hypothesis: There is effect of testing and correcting vitamin D status as regard ovulation in patients with PCOS

Conditions

• PCOS

Interventions

Type	Name	Description
DRUG	Vitamin D	6000 IU of vitamin D3
DRUG	Ovulatory Agent	only Clomophine Citrate

Timeline

• Start date: 2016-02-01
• Primary completion: 2018-11-01
• Completion: 2018-11-01
• First posted: 2016-01-14
• Last updated: 2018-11-16

Locations

1 site across 1 country: Egypt