NCT02402413

Ultrasound Three-dimensional Characterization of Ovarian Morphology in Women With Polycystic Ovary Syndrome (PCOS)

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: University of Cagliari · Academic / Other
• Sex: Female
• Age: 15 Years – 25 Years
• Healthy volunteers: Accepted

Summary

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders occurring in women of reproductive age. PCOS is considered a syndrome of ovarian dysfunction that is characterized by the heterogeneous clinical manifestation of infrequent or absent menstrual cycles, hyperandrogenism, and polycystic ovarian morphology. An important ultrasound parameter is the ratio stroma/ovary, the ratio of the volume, evaluated in two-dimensional ultrasound, of the stroma, that secrete androgen, and the ovary. It has been shown that when this ratio is higher than a third the levels of circulating androgens and high. Aim of the present study is to assess whether this ratio, determined with three-dimensional ultrasound, is correlated to the increase of androgens.

Conditions

• PCOS
• Hyperandrogenism

Interventions

Type	Name	Description
PROCEDURE	Ultrasound	The patients will be subjected to ultrasound bi-dimensional or three-dimensional. Will Be calculated the ratio stroma/volume with both methods
PROCEDURE	Determination of concentrations of androgens	Determination of concentrations of serum levels of circulating androgens
DEVICE	Three dimensional ultrasound probe	Capture of ovarian three dimensional volumes

Timeline

• Start date: 2016-06-01
• Primary completion: 2016-09-01
• Completion: 2016-12-01
• First posted: 2015-03-30
• Last updated: 2016-03-09