NCT01911468

Polycystic Ovary Syndrome and Liraglutide as Add-on Therapy on Metformin

Short-term Combined Treatment With Liraglutide and Metformin Leads to Significant Weight Loss in Obese Women With Polycystic Ovary Syndrome and Previous Poor Response to Metformin

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 36 (actual)
• Sponsor: University Medical Centre Ljubljana · Academic / Other
• Sex: Female
• Age: 18 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study was to determine whether combined treatment with liraglutide and metformin is more effective than liraglutide or metformin as monotherapy in the treatment of obese women with polycystic ovary syndrome (PCOS) who had been previously poor responders regarding weight reduction on metformin monotherapy. We anticipated greater changes in body weight in patients on combined treatment than in those on monotherapy with liraglutide or metformin.

Conditions

• PCOS
• Obesity

Interventions

Type	Name	Description
DRUG	metformin
DRUG	liraglutide
DRUG	metformin and liraglutide

Timeline

• Start date: 2011-11-01
• Primary completion: 2012-10-01
• Completion: 2013-04-01
• First posted: 2013-07-30
• Last updated: 2013-07-30

Locations

1 site across 1 country: Slovenia