Opioid Use

520 registered clinical trials studyying Opioid Use — 74 currently recruiting.

Status	Trial	Sponsor	Phase
Recruiting	Opioid Dispenser for Microdiscectomy/Laminectomy NCT06358040	Hospital for Special Surgery, New York	N/A
Not Yet Recruiting	OpioidRedoxStudyII NCT07338084	EPC Education s.r.o.	—
Recruiting	VibraCool Device to Reduce Pain and Opioid Use After Anterior Cruciate Ligament Reconstruction (ACLR) NCT06456268	Columbia University	N/A
Not Yet Recruiting	Evaluation of the Safety and Effects of Psychoactive Substances in People With Past Opioid Use NCT07218549	Christopher D. Verrico	Phase 1
Not Yet Recruiting	Mindfulness in Fracture Recovery and Reduction of Opioid Reliance: Evaluating the Feasibility of Implementing NCT07486505	McMaster University	N/A
Not Yet Recruiting	Autonomic Neural Blockade in Bariatric Surgery NCT07104825	Endeavor Health	N/A
Recruiting	Better Experiences in Substance Treatment: A Brief Alcohol-focused Intervention Tailored for Patients in Opioi NCT07342504	University of Notre Dame	N/A
Not Yet Recruiting	Autonomic Neural Field Block for Visceral Pain in Minimally Invasive Left-Sided Colectomy NCT07351994	Antonio Caycedo, MD	—
Recruiting	Infusion of Lidocaine and Steroids in Middle Meningeal Artery for Pain in Subarachnoid Hemorrhage NCT07294118	The University of Texas Medical Branch, Galveston	Phase 2
Recruiting	Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients NCT06903819	Texas Tech University Health Sciences Center	Phase 4
Withdrawn	The Impact of Intraoperative Methadone on Postoperative Opioid Use NCT07092475	University of Utah	Phase 3
Completed	Effect of Bilateral Rectointercostal Fascial Plane Block on Postoperative Pain After Laparoscopic Sleeve Gastr NCT07253610	Samsun University	N/A
Recruiting	Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation NCT06103370	Johns Hopkins University	N/A
Recruiting	Paracervical Injection and Opioid Use After Vaginal Hysterectomy for Prolapse NCT07213635	University of North Carolina, Chapel Hill	Phase 4
Completed	External Oblique Intercostal Block in Laparoscopic Cholecystectomy NCT07164664	Ondokuz Mayıs University	N/A
Not Yet Recruiting	Opioid Package Prototype (OPP) NCT04598074	UConn Health	N/A
Not Yet Recruiting	NOL-Guided vs Conventional Intraoperative Opioid Infusion on Outcomes in Geriatric Patients NCT07075003	Saglik Bilimleri Universitesi	—
Completed	Ketamine Administration for Postoperative Pain Management in Patients Undergoing Knee Arthroplasty NCT07059429	State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia	N/A
Recruiting	Effect of MGRNOX-Guided General Anesthesia on Opioid Consumption in Patients NCT07004686	Peking University Shenzhen Hospital	N/A
Recruiting	Evaluation of an Opioid Stewardship Program in Non-Cancer Patients NCT07102446	Korea University Guro Hospital	N/A
Completed	Outcome of Multimodal Anesthesia Bern NCT06985069	Insel Gruppe AG, University Hospital Bern	N/A
Recruiting	Effects of Lemborexant on Insomnia and Its Relationship to Mood and Behavior on Opioid Use Disorder Subjects NCT06981195	Virginia Commonwealth University	Phase 2
Recruiting	rTMS as Add on Treatment for Substance Use Disorders NCT06963476	Yale University	N/A
Recruiting	Guiding Opioid Administration by Nociception Level Index (NOL) in Patients With Regional Anesthesia NCT06905340	Universitätsklinikum Hamburg-Eppendorf	N/A
Withdrawn	HMP for Addictions Study NCT06063499	University of Wisconsin, Madison	N/A
Not Yet Recruiting	Can a Specific OMT Protocol Influence Patient Pain and Associated Analgesia Use for Primary Headache Disorders NCT06546462	New York Institute of Technology	N/A
Completed	THRIVE: Culturally AdapTed Harm Reduction Intervention NCT06609278	Brittany Miller-Roenigk	N/A
Completed	Testing STAR and TexSTAR: A Video and Text Messaging Intervention NCT06456190	University of Wisconsin, Madison	N/A
Recruiting	Comparison of Pain Relief After Arthroscopic Knee Surgery: Adductor Canal Block and Genicular Nerve Block NCT06909851	Başakşehir Çam & Sakura City Hospital	N/A
Recruiting	Machine-Learning Prediction and Reducing Overdoses With EHR Nudges NCT06806163	University of Pittsburgh	N/A
Recruiting	Analgesic Efficacy of Intravenous Ketamine as a Continuous Infusion vs PCA in the Management of Acute Postoper NCT06774274	Universidad de Antioquia	Phase 4
Recruiting	Intraoperative Autonomic Blockade for Laparoscopic Cholecystectomy NCT06753500	Universidad Simón Bolívar	Phase 4
Recruiting	Opioid Misuse in Patients with Cancer NCT06489769	Rigshospitalet, Denmark	—
Completed	Patient-Centered Chronic Pain Care NCT05256394	University of Florida	N/A
Recruiting	Overdose Recovery and Care Access (ORCA) Qualitative Stakeholder Interviews and County-level Data NCT06768814	University of Washington	N/A
Not Yet Recruiting	The Effect of Nociception Level (NOL) Monitoring on Intraoperative Opioid Consumption in Hip Surgeries NCT06558149	Kocaeli University	N/A
Recruiting	fMRI and Opioid Abstinence NCT06651333	Yale University	—
Recruiting	Improving Sleep and Reducing Opioid Use in Individuals With Chronic Pain NCT06345872	University of South Florida	N/A
Not Yet Recruiting	CPB for Arthroscopic Hip Surgery NCT06337968	The Second Hospital of Shandong University	N/A
Recruiting	Timing of TAP Blocks in Bariatric Surgery NCT06270147	McMaster University	Phase 2
Recruiting	PRIDE III Prison Interventions and HIV Prevention Collaboration NCT06962033	Yale University	N/A
Unknown	Opioid Reduction Strategy South Western Ontario NCT04944225	London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's	N/A
Recruiting	Transcutaneous Auricular Neurostimulation After Lumbar Surgery NCT06100172	University of Texas Southwestern Medical Center	N/A
Completed	Medical Cannabis as an Opiate Alternative NCT07194928	University of Pennsylvania	—
Recruiting	Nonopioid Pain Control Regimen After Open Reduction and Internal Fixation of Traumatic Fractures NCT06113211	Henry Ford Health System	Phase 4
Recruiting	Effects of Erector Spinae Plane Block on Postoperative Pain Following Lumbar Fusion Surgery NCT06528288	University of Massachusetts, Worcester	N/A
Not Yet Recruiting	Optimizing Research Data Acquisition With Smart Pill Bottles NCT06522698	Ciusss de L'Est de l'Île de Montréal	N/A
Completed	Decreasing Loneliness to Optimize Pain Care NCT06285032	University of Washington	N/A
Recruiting	Paravertebral Block and Erector Spinae Plane Block on Intraoperative Opioid Consumption Using NoL Index NCT06507293	Kocaeli University	N/A
Recruiting	Opioid Prescribing Practices in Laparoscopic Gynecologic Surgery NCT06532708	University of Tennessee	N/A
Recruiting	Understanding the Acute Pain Phenotype in Patients Undergoing Surgery NCT06466941	Brigham and Women's Hospital	—
Completed	Ultrasound Guided Serratus Anterior Plane Block in ED Patients With Rib Fractures NCT06299137	Rhode Island Hospital	EARLY_Phase 1
Recruiting	QL vs LAI for Palatoplasty NCT06420336	Medical University of South Carolina	N/A
Completed	Comparison of Postoperative Analgesia Methods in Elective Cesarean Section Surgeries NCT06425718	Marmara University	N/A
Recruiting	Opioid Use After Laparoscopic Salpingectomy NCT06434233	Johns Hopkins University	Phase 4
Completed	Comparing Intrathecal Morphine With Modified Thoracoabdominal Nerve Block Through Perichondral Approach in Maj NCT06346860	Marmara University	N/A
Completed	Opioid-based Versus Opioid-free Endotracheal Intubation NCT06464393	Aretaieion University Hospital	N/A
Completed	Organization-level Youth Engagement Approach for Substance Misuse Prevention NCT05736211	Wake Forest University Health Sciences	N/A
Recruiting	Non-invasive Vagal Nerve Stimulation in Opioid Use Disorders UH3 NCT05834478	Emory University	Phase 3
Not Yet Recruiting	Gut Microbiota Dysbiosis in Opioid Use Disorders: Implications for Clinical Symptoms and Relapse Rate. NCT06231849	Assiut University	—
Unknown	Opioid Free Anaesthesia Versus Opioid Based Anesthesia for Laparscopic Cholecystectomy NCT06231992	Al-Azhar University	N/A
Completed	Dexmedetomidine Use in SZMN Blocks for Pediatric T&A Pain Control NCT05208892	Stanford University	N/A
Unknown	A Project to Test the Efficacy and Safety of An Innovative Treatment for Opiate Use Disorders. NCT05995873	MindLight, LLC	N/A
Completed	Patient Reported Outcomes, Postoperative Pain and Pain Relief After Day Case Surgery (POPPY) NCT06008496	University Hospital Plymouth NHS Trust	—
Enrolling By Invitation	Exparel vs. Marcaine ESP Block for Post-cardiac Surgical Pain NCT06077422	Rutgers, The State University of New Jersey	Phase 2 / Phase 3
Completed	Pre-post Erector Spine Plane Block-spinal Surgery NCT06215053	Aydin Adnan Menderes University	N/A
Recruiting	Pregabalin Plus Lofexidine for the Outpatient Treatment of Opioid Withdrawal NCT05995535	University of Pennsylvania	Phase 2
Withdrawn	Accelerated Intermittent Theta-Burst Stimulation for Opiate Use Disorder NCT03804619	Stanford University	N/A
Completed	Guiding Opioid Administration in Patients With Regional Anesthesia NCT06040307	Universitätsklinikum Hamburg-Eppendorf	N/A
Unknown	Intraoperative Autonomic Neural Blockade NCT06137924	Universidad Simón Bolívar	Phase 3
Recruiting	Translation and Validation of the COMM and ASI-SR NCT06084520	Uppsala University	—
Unknown	Effect of Mindfulness on Pain After Total Knee Arthroplasty NCT06118073	Rothman Institute Orthopaedics	N/A
Recruiting	Effects of Erector Spina Plane Block and Paravertebral Block on Early Postoperative Pulmonary Function Test Pa NCT06584201	Başakşehir Çam & Sakura City Hospital	—
Completed	Persistent Pain After Knee Replacement NCT05900791	University Hospital Bispebjerg and Frederiksberg	—
Completed	Managing Opioid Related Sleep Apnea With Acetazolamide NCT06043830	University of California, San Diego	Phase 2
Completed	Aromatherapy in Total Knee Replacement NCT06045078	Hospital for Special Surgery, New York	N/A
Active Not Recruiting	A Pain and Coordination Plan for Reduced Opioid Use After Accidental Injuries NCT06055205	University of Oslo	N/A
Recruiting	Pain AND Opioids After Surgery NCT05877157	University of Aberdeen	—
Terminated	Feasibility and Acceptability of Oxygen Saturation Monitoring Using Masimo SafetyNet Alert (MSNA) in a Support NCT06217380	Masimo Corporation	N/A
Completed	Phase Ib/2a Drug-drug Interaction Study of a Combination of 45mg Dextromethorphan With 105 mg Bupropion NCT05976646	Virginia Commonwealth University	Phase 1 / Phase 2
Recruiting	Motivational Interviewing and Mindfulness-Oriented Recovery Enhancement NCT06033599	Rutgers, The State University of New Jersey	Phase 3
Recruiting	Implementation and Effectiveness of Mindfulness Oriented Recovery Enhancement as an Adjunct to Methadone Treat NCT06032559	Rutgers, The State University of New Jersey	Phase 3
Completed	Persistent Pain After Hip Replacement NCT05845177	University Hospital Bispebjerg and Frederiksberg	—
Recruiting	Sex Hormones, Postoperative Pain and Opioid Use NCT06023225	Washington University School of Medicine	—
Unknown	Preoperative Gabapentin for Cosmetic Breast Surgery NCT05997355	University of Puerto Rico	N/A
Recruiting	Rural Expanded Access to OUD Care & Linkage Using Toxicologists for Telehealth Initiated Treatment NCT05711056	Emory University	N/A
Recruiting	The Effect of Preoperative Maxigesic® on Intraoperative Remifentanil Requirement NCT06015711	Ajou University School of Medicine	N/A
Completed	Physical Therapy Integrated With Mindfulness for Patients With Chronic Pain and Opioid Treatment NCT05875207	University of Utah	N/A
Unknown	Opioid-sparing Versus Sevoflurane Anesthesia on Early Postoperative Hypoventilation in Laparoscopic Bariatric NCT05962671	Tanta University	Phase 4
Completed	Guiding Aging Long-Term Opioid Therapy Users Into Safer Use Patterns NCT05808127	University of Southern California	N/A
Completed	Reinforcing Effects of Marijuana and Opioids NCT05485012	Shanna Babalonis, PhD	Phase 1
Recruiting	Treating Polysubstance Use Using a Novel Digital Technology NCT05766631	Friends Research Institute, Inc.	Phase 3
Unknown	Effect of Adding TTPB to SAPB in Breast Cancer Surgery NCT06082141	Bezmialem Vakif University	N/A
Terminated	The Effects of Daily Anti-inflammatory Supplementation on Foundation Pain Index Scores in Chronic Opiate Patie NCT05896878	Hudson Medical	N/A
Completed	Increasing Access to Evidence-based Treatment for Chronic Pain and Opioid Use Disorder: Adapting Acceptance an NCT06581276	Montefiore Medical Center	N/A
Active Not Recruiting	Patient Utilization of Opioid Destruction Bags in the Post-op Period NCT05875857	University of Nebraska	N/A
Completed	The Postoperative Lidocaine and Ketamine Effects on Morphine Requirement in Bariatric Surgery NCT05591105	Tiva Group	—
Recruiting	Enhanced Recovery After Major Surgery and Chronic Pain for Total Knee Arthroplasty NCT05981105	Hospital for Special Surgery, New York	N/A
Completed	Genicular and Anterior Femoral Cutaneous Nerve Blocks for Total Knee Arthroplasty NCT05980546	Hospital for Special Surgery, New York	Phase 4
Recruiting	Neuroimaging of Opioid Phase (OPAL) NCT05905419	Duke University	N/A
Terminated	Duloxetine Impact on Postoperative Pain Control and Outcomes NCT05611749	Scripps Health	Phase 2
Completed	Psychological Intervention Using Smartphone Technology to Alleviate Malignant Pain NCT05774197	University of Oklahoma	N/A
Unknown	Effectiveness of Combining Erector Spinea Block With Non Opioid Infusions as Opioid Free Anesthesia in Spine S NCT05850468	Ain Shams University	N/A
Completed	Comparison of Pain Relief After Hip Fracture Surgery: Hip and Groin Nerve Block NCT06443892	Başakşehir Çam & Sakura City Hospital	—
Completed	Co-Use of Opioid Medications and Alcohol Prevention Study NCT05599672	University of Utah	N/A
Recruiting	Laparoscopic Guided Peri-wound Transversus Abdominis Plane Block With Bupivacaine Versus Local Wound Infiltrat NCT05930184	Khon Kaen University	Phase 2 / Phase 3
Active Not Recruiting	Personalization of Opioid Prescription Following Orthognathic Surgery NCT05708521	Nova Scotia Health Authority	Phase 4
Recruiting	Pregabalin in the Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy (LSG). NCT05804591	Medical University of Warsaw	Phase 4
Suspended	Opioid-Free Pain Control Regimen Following Robotic Radical Prostatectomy NCT05597878	Wake Forest University Health Sciences	Phase 2 / Phase 3
Active Not Recruiting	ENDOblock: Bilateral Superficial Cervical Blocks With Local Wound Infiltration in Thyroid Surgery NCT05805423	University of California, Davis	N/A
Completed	Enhancing Prospective Thinking in Early Recovery (PARK) NCT05908097	Indiana University	EARLY_Phase 1
Completed	Mindfulness for Pain and Suicide NCT05286112	Canandaigua VA Medical Center	N/A
Completed	Comparing Intrathecal Morphine With Erector Spina Plane Block in Open Gastrectomy Surgery NCT05706285	Marmara University	—
Unknown	Comparison of the Effect of Lidocaine Infusion Applied at Different Doses During Lumbar Spinal Surgery on Hemo NCT05936190	Ankara University	N/A
Completed	Conditioned Open-label Placebo (COLP) for Peri-operative Pain Management in Patients With Head and Neck Cancer NCT04973748	Johns Hopkins University	N/A
Terminated	Novel Induction to Buprenorphine/Naloxone NCT05644587	Bicycle Health	Phase 4
Completed	Paragastric Autonomic Neural Blockade as Part of Combined Anesthesia. NCT05668845	Universidad Simón Bolívar	N/A
Completed	Analgesic Effects of Intrathecal Morphine and Bilateral Erector Spina Plane Block in Elective Cesarean Section NCT05698927	Marmara University	N/A
Unknown	GP Remote Consultation to Reduce Opioid Prescribing NCT05276089	Dr Yu Fu	N/A
Active Not Recruiting	Reduced Opioid Prescription After Laparoscopic Hysterectomy NCT05548582	Johns Hopkins University	N/A
Completed	Opioid Use After Urogynecologic Procedures: Using a Predictive Calculator NCT05571072	David Sheyn	N/A
Unknown	Randomized Trial of Narcotic vs Non-Narcotic Pain Modulation After Labrum Repair NCT05974423	The Cooper Health System	Phase 4
Completed	Affective Effects of Pre-surgery Opioids: a Randomized, Doubleblind Placebo-controlled Trial NCT05639712	Oslo University Hospital	Phase 4
Recruiting	Personalized Perioperative Analgesia Platform (PPAP) for Cesarean Section NCT05380531	Senthil Sadhasivam	N/A
Unknown	Preventing Opioid Misuse Through Safe Opioid Use Agreements Between Patients and Surgical Providers NCT06167759	The University of Texas Health Science Center, Houston	N/A
Recruiting	Neural Mechanisms of Meditation for Opioid-Treated Chronic Low Back Pain NCT05607381	University of Utah	N/A
Completed	Two Approaches of Transversus Abdominis Block (TAP ) in Laparoscopic Cholecystectomy NCT05946733	Menoufia University	N/A
Unknown	Early Treatment With Invasive Technique in Cancer Pain Management NCT05594459	Regina Elena Cancer Institute	N/A
Completed	Improving Pain Disability With the Use of Oral Cannabinoids NCT05351905	University Health Network, Toronto	N/A
Completed	Opioid Consumption and Disposal After Shoulder Arthroplasty NCT05525975	Brendan M. Patterson	N/A
Completed	Testosterone Replacement to Alleviate Pain in Postmenopausal Women (TRAPP Trial) NCT04895306	Brigham and Women's Hospital	Phase 2
Completed	Cannabidiol for Bilateral Total Knee Arthroplasty NCT04749628	Hospital for Special Surgery, New York	Phase 4
Recruiting	Auriculo-Nerve Stimulation on Post-Operative Opioid Requirement NCT05506878	Jacques E. Chelly	N/A
Recruiting	Virtual Reality and Olfactory Stimuli Multimodal Intervention to Reduce Post-Operative Pain and Anxiety in Pat NCT04912531	Massachusetts General Hospital	N/A
Unknown	POINT - Preventing an Opioid Epidemic in Norway: Focusing on Treatment of Chronic Pain NCT05828121	Helse Stavanger HF	N/A
Completed	Opioid Education in Total Knee Arthroplasty NCT05593341	Hospital for Special Surgery, New York	N/A
Unknown	Pregabalin Versus Gabapentin Opioid Sparing Effect in Discectomy NCT05539924	Research Institute of Ophthalmology, Egypt	Phase 3
Unknown	Return to Work - Will Brief Intervention Reduce Opioid-induced Back Pain? NCT05437861	University Hospital, Akershus	N/A
Recruiting	Culturally Responsive Community Driven Substance Use Recovery for Black and Latinx Population NCT05260047	Yale University	N/A
Completed	The Effects of Frailty on Opioid Consumption NCT05445700	Selcuk University	N/A
Completed	Incorporating Acupuncture Into ERAS for Ambulatory Total Hip Replacement (THR) Surgery NCT05384860	Hospital for Special Surgery, New York	N/A
Completed	Eliminating Narcotic Prescriptions from Outpatient Minimally Invasive Gynecologic Surgery NCT04837014	McGill University Health Centre/Research Institute of the McGill University Health Centre	N/A
Completed	Slow Opioid Tapering Pilot Study of Patients Using Chronic Opioid Therapy NCT05297396	Mayo Clinic	N/A
Suspended	Buprenorphine for Probationers and Parolees: Bridging the Gap Into Treatment NCT03616236	Friends Research Institute, Inc.	Phase 3
Completed	Impact of DuoTherm on Opioid Use and Low Back Pain NCT04491175	MMJ Labs LLC	N/A
Unknown	Using Mobile Devices for Neurofeedback to Reduce Opioid Use in Chronic Pain NCT04838925	CrossComm, Inc.	N/A
Active Not Recruiting	Trauma Intervention to Optimize PrEP Among Women Who Inject Drugs NCT05192434	Drexel University	N/A
Completed	The Adolescent Surgery Experience: A Mixed Methods Analysis NCT05482919	Children's Hospital of Philadelphia	—
Completed	Effects of the Nottingham Augmented Reality (AR) App for Arthritis Hand Joint Pain NCT05634291	VRx Medical Inc	N/A
Completed	Effect of Opioid-free Anesthesia on PostOperative Nausea and Vomiting in Patients Undergoing Video-assisted Th NCT05411159	Beijing Chao Yang Hospital	N/A
Withdrawn	Can Simplified and More Detailed Instructions Affect Post-Operative Narcotic Consumption NCT03534102	Brigham and Women's Hospital	Phase 4
Completed	Dexmedetomidine in Thoracoscopic Surgery: Opioid-Sparing Strategy NCT05431322	Kaohsiung Veterans General Hospital.	N/A
Withdrawn	Long Acting Buprenorphine Injection Compared to Sublingual Buprenorphine/Naloxone Films NCT03744663	Wake Forest University Health Sciences	Phase 2
Completed	Postoperative Opt-In Narcotics Treatment in Breast NCT05078398	University of California, Los Angeles	N/A
Completed	Increasing Implementation of Post-Operative Opioid Prescribing Guidelines NCT05358522	University of Pennsylvania	N/A
Terminated	Low-dose KETamine as an Adjunct to MOrphine for Acute Pain in the ED NCT05422001	University of Aarhus	Phase 4
Recruiting	ESP Block Versus Wound Infiltration for Laminectomy NCT05271331	University of Padova	N/A
Completed	A Pilot Study Using Facebook to Support Opioid Recovery Among American Indian Women NCT05340855	Mayo Clinic	N/A
Completed	Music Therapy in the Treatment of Perioperative Anxiety and Pain NCT05263635	University of Pittsburgh	N/A
Completed	Chest dRain rEmoval intrAoperatively afTer thoracOscopic Wedge Resection NCT05358158	Rigshospitalet, Denmark	N/A
Completed	Comparison of Short-term Sustained-release Opioid in Open Abdominal Urologic Surgeries NCT05375916	University of Alberta	N/A
Completed	Efficiency And Quality In Post-Surgical Pain Therapy After Discharge NCT05221866	University of Nebraska	N/A
Withdrawn	Impact of Coaching Patients on Pain Control With and Without Financial Incentivization NCT04113252	Wake Forest University Health Sciences	N/A
Unknown	Standardization of Post-operative Opiate Prescriptions for Same-day Ankle and Wrist Fracture Surgeries NCT05322564	The Ottawa Hospital	N/A
Completed	Assessing the Impact of Opioid-Free Anesthesia Using the Modified Mulimix Technique. NCT06216210	Zulekha Hospitals	—
Active Not Recruiting	Peer Supported Collaborative Care Mental Health and Substance Use Disorder Care NCT04601064	Johns Hopkins University	N/A
Completed	Peer Activate: Trial of Peer-Delivered Behavioral Activation for Methadone Adherence NCT05299515	University of Maryland, College Park	N/A
Completed	Postoperative Opioid Use and Ileus Occurrence---A Case Control Study NCT05262569	Peking University People's Hospital	—
Unknown	The Association of Microbiome Patterns With Chronic Opioid Use NCT05304403	University of California, San Diego	—
Unknown	Ultrasound-guided Erector Spinae Plane Block Using Catheter for Video-assisted Thoracoscopy NCT05337956	Security Forces Hospital	N/A
Withdrawn	NiteCAPP_HELPS_WD: Improving Sleep and Reducing Opioid Use in Chronic Pain Patients NCT05226026	University of Missouri-Columbia	N/A
Completed	Precision Opioid Care After Cesarean Delivery (PRECISE-CD) NCT05280743	Grace Lim, MD, MS	—
Completed	A Pilot Study Investigating the nCAP Signal Relief Patch in Subjects Undergoing Primary Hip or Knee Replacemen NCT05252858	Jacques E. Chelly	N/A
Completed	Opioid-free Anesthesia With ESPB in VATS Operation NCT05321576	Marmara University	N/A
Completed	Optimization and Multi-Site Feasibility of Yoga for Chronic Pain in People in YOGAMAT-II - Phase II NCT04641221	Butler Hospital	N/A
Completed	Providing PrEP, Hepatitis C Treatment, and MOUD Through Telemedicine at Greensboro SSP NCT05108935	Duke University	N/A
Completed	Persistent Opioid Consumption After Major Abdominal Surgery and Its Determinants NCT05197465	Centre hospitalier de l'Université de Montréal (CHUM)	—
Terminated	TAP Block Using Liposomal Bupivacaine for Post-cesarean Delivery Analgesia- Walking Towards Recovery NCT04393207	Yale University	Phase 4
Completed	Effects of Hypnosis Therapy on Outcomes in Total Knee Replacement NCT05818969	Foundation for Orthopaedic Research and Education	N/A
Terminated	H-coil TMS to Reduce Pain: A Pilot Study Evaluating Relative Efficacy of the H1 vs H7 Coil NCT04203199	Wake Forest University Health Sciences	N/A
Completed	Optimizing CAB-LA as PrEP for Women Who Inject Drugs NCT05799339	Alexis Roth	—
Recruiting	Pain Alleviation With Testosterone in Opioid-Induced Hypogonadism NCT04798469	Brigham and Women's Hospital	Phase 2
Completed	Effects Of Additional MgSO4 30 Mg/KgBW Intravenous and Ketorolac NCT05609955	Indonesia University	Phase 4
Completed	Postoperative Telehealth Mindfulness Intervention After Spine Surgery NCT04648683	Vanderbilt University Medical Center	N/A
Unknown	Influence of Δ9-tetrahydrocannabinol (THC) on Oxycodone Induced Ventilatory Depression in Healthy Volunteers NCT05235503	Leiden University Medical Center	Phase 4
Withdrawn	Surviving Opioid Overdose With Naloxone Education and Resuscitation Trial (SOONER) NCT04740099	Unity Health Toronto	N/A
Unknown	Effectiveness of iPACK on Postoperative Pain From Hamstring Autograft Following ACL Repair NCT05080348	Brenton Alexander	N/A
Completed	FOREward Together: Training Peer Recovery Coaches to Promote Retention and Adherence to MOUD NCT05098795	Henry Ford Health System	N/A
Withdrawn	Liposomal Bupivacaine in Adductor Canal Blocks (ACB) NCT04539730	University of Miami	Phase 4
Completed	SZMN Blocks for Pain Control in Pediatric Patients Undergoing T&A NCT04797559	Stanford University	N/A
Completed	Perioperative Intravenous Lidocaine in Liver Surgery NCT05153785	Lund University Hospital	Phase 2 / Phase 3
Recruiting	Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression NCT05058287	Hospital for Special Surgery, New York	Phase 3
Completed	The Experiences of People Prescribed Opioid Pain Medicines NCT04888897	University of Nottingham	—
Unknown	Are Adductor Canal Blocks With Bupivacaine and Added Magnesium Better at Managing Post-operative Pain Than Bup NCT05091138	Wayne State University	N/A
Completed	Obstetric Liposomal Bupivacaine Via Surgical Transversus Abdominis Plane Block for Post Cesarean Pain Control NCT04897841	University of Wisconsin, Madison	Phase 4
Completed	Lidocaine Patches After Cesarean Section NCT04443569	Yale University	Phase 3
Completed	Prediction of Postoperative Pain by Nociception Monitoring NCT05063227	Universitätsklinikum Hamburg-Eppendorf	—
Unknown	Impact of Bilateral Deep Parasternal Intercostal Plane Block on Intraoperative Opioid Consumption in Open Hear NCT05103787	Indonesia University	N/A
Unknown	Cervical Erector Spinae Block Versus Interscalene Block for Shoulder Surgery NCT04435236	Ataturk University	N/A
Recruiting	Opioid Free Anaesthesia-Analgesia Strategy on Surgical Stress and Immunomodulation in Elective VATS-Lobectomy NCT05172739	University of Crete	Phase 4
Terminated	Cognitive Functioning in Opioid Use Disorder NCT05001789	New York State Psychiatric Institute	N/A
Recruiting	Encouraging Abstinence Behavior in a Drug Epidemic: Optimizing Dynamic Incentives NCT04927143	Wake Forest University Health Sciences	N/A
Unknown	Naloxone Education in Total Joint Patients NCT04868552	Carilion Clinic	N/A
Unknown	The Study of Hemp Oil CBD for Evaluation of Efficacy and Safety in Treatment of Pain, Anxiety and Insomnia Man NCT04729244	Advanced Pain and Rehab Specialists	Phase 1
Completed	Evaluation of Medical Cannabis and Prescription Opioid Taper Support for Reduction of Pain and Opioid Dose in NCT04827992	Massachusetts General Hospital	N/A
Unknown	Opioid-Redox Study NCT03105232	Pavol Jozef Safarik University	—
Completed	The Association Between Loneliness and Substance Use NCT04938492	University of Rochester	N/A
Recruiting	Reducing Opioid Mortality in Illinois NCT04925427	University of Chicago	N/A
Completed	Prospective Randomized Trial of CPAP for SDB in Patients Who Use Opioids NCT04928157	University of California, San Diego	Phase 2
Withdrawn	Postop Pain Control in Hip Fracture Surgery: Fascia Iliaca Compartment Block Versus Fracture Block NCT04335461	Montefiore Medical Center	EARLY_Phase 1
Completed	Suicide Prediction and Prevention for People at Risk for Opioid Use Disorder: Supplement to COMPUTE 2.0 NCT04939727	HealthPartners Institute	N/A
Completed	Opioid Reduction Program for Total Knee Replacement Patients NCT05414942	University of Tennessee	N/A
Terminated	Opioid Free vs. Standard Perioperative Pain Regimen for Anterior Cervical Discectomy and Fusion (ACDF) Surgery NCT04990804	Vanderbilt University Medical Center	Phase 4
Completed	Personalized Feedback Intervention for Alcohol and Opioid Use Among Adults With Chronic Pain NCT04592978	Syracuse University	N/A
Active Not Recruiting	Continuous Serratus Anterior Blockade for Sternotomy NCT04648774	Nova Scotia Health Authority	N/A
Completed	Efficacy of Erector Spinae Plane (ESP) Block in Patients With Inflammatory Bowel Disease (IBD) NCT06230003	Samuel Lunenfeld Research Institute, Mount Sinai Hospital	N/A
Unknown	Predicting Chronic Opioid Use Following Lower Extremity Joint Arthroplasty NCT04974463	University of California, San Diego	—
Unknown	Predicting Chronic Pain Following Breast Surgery NCT04967352	University of California, San Diego	—
Unknown	ERAS Protocol for Single-level Posterior Lumbar Arthrodesisprospective Study. NCT05022745	AZ Nikolaas	Phase 4
Unknown	Prevention of Opioid Use Disorder After Surgery NCT04394559	Brigham and Women's Hospital	N/A
Unknown	Pharmacist-led Pharmacogenomic Clinical Service Within the Program of All-inclusive Care for the Elderly NCT04971902	Tabula Rasa HealthCare	—
Completed	Comparing the Impact of Mindful Interoceptive Mapping and Mindful Breathing on Pain and Opioid Use NCT04523766	University of Utah	N/A
Completed	Opioid Use After Thyroid and Parathyroid Surgeries NCT04955444	The Methodist Hospital Research Institute	N/A
Completed	INTEGRA: A Vanguard Study of Health Service Delivery in a Mobile Health Delivery Unit NCT04804072	HIV Prevention Trials Network	N/A
Completed	The Effect of Bilateral Erector Spina Plane Block on Postoperative Pain in Adult Cardiac Surgery. NCT04906239	Kahramanmaras Sutcu Imam University	N/A
Unknown	Comparing a Patient Self-Assessment Software to Treatment as Usual in Opioid Prescriber and Patient Opioid Out NCT04945525	Sure Med Compliance	N/A
Enrolling By Invitation	Total Shoulder Arthroplasty Preoperative Pain Threshold and Association With Postoperative Opioid Consumption NCT06133933	The Cooper Health System	—
Terminated	PROUD Study - Preventing Opioid Use Disorders NCT04766996	Emory University	Phase 4
Completed	Impact of Counseling and Education on Opioid Consumption After ACL Reconstruction NCT04885231	University of Maryland, Baltimore	N/A
Unknown	Impact of a Behavioral Tele-health Program on the Quality of Recovery for Patients Undergoing Total Joint Repl NCT05367050	Lucid Lane, Inc	N/A
Completed	Developing and Pilot Testing an Opioid Tapering Protocol NCT04257695	Albert Einstein College of Medicine	N/A
Completed	Evaluation of a Patient-Centred, Multidisciplinary Opioid Tapering Program for Individuals With Chronic Non-Ca NCT04902547	University of Manitoba	N/A
Completed	Ketamine Versus Fentanyl for Surgical Abortions NCT04871425	University of Washington	Phase 4
Completed	Leveraging Social Networks to Increase COVID-19 Testing Uptake NCT04873401	New York State Psychiatric Institute	N/A
Recruiting	Young Houston Emergency Opioid Engagement System NCT04811014	The University of Texas Health Science Center, Houston	Phase 4
Completed	Nudging Providers to Curtail Dangerous Opioid Prescribing: A Trial to Investigate Mechanisms NCT04628832	Columbia University	N/A
Terminated	Non-Opioid Pain Medications After Intracapsular Adenotonsillectomy NCT04791761	David Chi, MD	Phase 1 / Phase 2
Completed	The Impact of Perioperative Ketamine Infusion on Surgical Recovery NCT04625283	Vanderbilt University Medical Center	Phase 4
Completed	Femoral Triangle Block With Popliteal Plexus Block Versus Femoral Triangle Block Versus Adductor Canal Block f NCT04854395	Regionshospitalet Silkeborg	Phase 4
Terminated	Perioperative Pregabalin for Reducing Opioid Consumption After Cardiac Surgery NCT04517110	Hamilton Health Sciences Corporation	Phase 3
Completed	Nonopioid Analgesics and Cholecystectomy NCT04622813	American University of Beirut Medical Center	Phase 3
Completed	Near-infrared Spectroscopy-based Neurofeedback as Adjunct to Mindfulness-Oriented Recovery Enhancement in Pers NCT04902339	University of Utah	N/A
Completed	Distribution of Medication Disposal Packets - Acute Opioid Prescribing NCT05169281	University of Pennsylvania	N/A
Completed	The Behavioral Effects of Opioids and Alcohol NCT04300751	Sharon Walsh	Phase 1
Completed	Intra-operative Uterosacral Ligament Bupivacaine Injection During Minimally Invasive Hysterectomy NCT04157075	Johns Hopkins University	EARLY_Phase 1
Completed	Perioperative Dexamethasone Reduces Postoperative Pain and Nausea After Hip Arthroscopy NCT04610398	Balgrist University Hospital	Phase 3
Completed	Dronabinol in Total Knee Arthroplasty (TKA) NCT04734080	Hospital for Special Surgery, New York	Phase 4
Completed	SMART Trial: Intrapersonal and Interpersonal Stigma Reduction NCT04693416	University of Tennessee	Phase 2
Completed	RelieVRx for Total Knee Arthroplasty (TKA) for the Reduction of Acute Postoperative Pain and Opioid Use NCT04010266	AppliedVR Inc.	N/A
Completed	Effects of US-guided SAPB During Breast Surgery NCT04824833	Zonguldak Bulent Ecevit University	N/A
Completed	Optimization and Multi-Site Feasibility of Yoga for Chronic Pain in People in YOGAMAT-II - Phase I NCT04646148	Butler Hospital	N/A
Active Not Recruiting	Stopping Opioid Overuse in Obstetrics to Halt Exposure Trial NCT04680221	University of Missouri, Kansas City	Phase 4
Completed	Opioid Approach Bias Modification NCT04436926	University of California, San Francisco	N/A
Terminated	Methadone for Spinal Fusion Surgery. NCT04764825	University of Aarhus	Phase 4
Completed	Erector Spinae Plane Blocks for Adolescent Idiopathic Scoliosis NCT04500613	Hospital for Special Surgery, New York	N/A
Unknown	Assessment of the Development of Postoperative Persistent Postoperative Pain NCT05370924	A.O.U. Città della Salute e della Scienza	—
Unknown	Evaluation of Exparel Adductor Canal Field Block for Pain Control After ACL Reconstruction NCT04764916	Carilion Clinic	Phase 3
Completed	Preventing Opioid Use Among Justice-involved Youth as They Transition to Adulthood Leveraging Safe Adults (LeS NCT04678960	Texas Christian University	N/A
Completed	Prospective Multicentre Study of the Use of Ketamine in the Treatment of Refractory Chronic Pain in the French NCT04459234	Centre Leon Berard	—
Unknown	PENG vs Intra-articular Injection for Hip Arthroscopy NCT04698746	Bezmialem Vakif University	N/A
Active Not Recruiting	Opioid Analgesic Reduction Study NCT04452344	Rutgers, The State University of New Jersey	Phase 3
Completed	Prevention Interventions for Opioid Misuse NCT04550715	University of Michigan	N/A
Active Not Recruiting	Project 1 Aim 2, Adaptations of the Brain in Chronic Pain With Opioid Exposure NCT05463367	Northwestern University	Phase 2
Unknown	Healthy Adult Male Facial Skin Surface Lipid Pheromone p.o. to Treat Opioid Addiction NCT03394911	Bubba Nicholson	Phase 3
Completed	Effects of Hypnosis Therapy on Outcomes in Shoulder Replacement Therapy NCT04889833	Foundation for Orthopaedic Research and Education	N/A
Completed	Chronic Pain, Opioid Use, and Epidermal Nerve Fiber Density NCT04801498	University of Kansas Medical Center	—
Active Not Recruiting	Evaluation of Neuroinflammation FNOS PET/CT in HIV (+) and (-) Subjects With OUD and Healthy Controls NCT04401917	University of Pennsylvania	EARLY_Phase 1
Unknown	Comparison of Thoracolumbar Interfascial and Erector Spinae Plane Block on Analgesic Efficiency of After Spina NCT03931343	Bezmialem Vakif University	N/A
Completed	The Impact of Sublingual Sufentanil on Postoperative Pain and Analgesic Requirements in Spine Surgery Patients NCT04263909	Brigham and Women's Hospital	Phase 4
Completed	Understanding the Postpartum Pain Experience in Women of Minority Race/Ethnicity NCT04601246	Northwestern University	—
Terminated	Comparison of Quadratus Lumborum Block Types NCT04588389	University of Massachusetts, Worcester	Phase 3
Withdrawn	Opioids and Smoking Cessation NCT03857139	University of Houston	Phase 4
Completed	TACUNA (Traditions and Connections for Urban Native Americans) NCT04617938	RAND	N/A
Completed	Non-Invasive Vagal Nerve Stimulation in Opioid Use Disorders NCT04556552	Emory University	Phase 3
Completed	Inflammatory Response to Opioid Versus Opioid Free Anesthesia NCT04854252	University of Guadalajara	N/A
Completed	Providing Suboxone and PrEP Using Telemedicine NCT04521920	Duke University	N/A
Completed	How Does the Addition of Adductor Canal Block to Local Infiltration Affect Recovery in Patients Undergoing Tot NCT04648072	Health Sciences North Research Institute	N/A
Completed	Efect of Erector Spina Plane Block on Mastectomy NCT04824300	Marmara University	N/A
Completed	Esophageal Dysfunction Associated With Opioids: Clinical Response and Manometric Findings After Opioid Discont NCT06522633	Hospital Clinic of Barcelona	Phase 3
Completed	Nociception-Level (NOL) for the Assessment of Pain in Patient Unable to Self-Report NCT04581642	Medasense Biometrics Ltd	—
Completed	Reflexology Socks and Opioid-induced Constipation NCT05314335	Muğla Sıtkı Koçman University	N/A
Recruiting	Hip Arthroscopy Postoperative Opioid Demands NCT04094701	Rush University Medical Center	N/A
Unknown	Insomnia and Sleep Disturbances in Chronic Pain Patients - Relation to Physical Activity Level and Opioid Use NCT04649281	Göteborg University	N/A
Recruiting	Opioid Free Anesthesia-Analgesia Strategy and Surgical Stress in Elective Open Abdominal Aortic Aneurysm Repai NCT04894864	University of Crete	Phase 4
Completed	Do Discounted Vouchers for Medical Cannabis Reduce Opioid Use in Adults With Pain NCT04495725	Vireo Health	N/A
Completed	Does Medical Cannabis Reduce Opioid Use in Adults With Pain NCT04308148	Albert Einstein College of Medicine	—
Recruiting	Opioid Dispensing Device for Post-Operative Pain in Cancer Patients NCT05585788	Columbia University	N/A
Active Not Recruiting	SLeep and OPioid UsE in Patients Undergoing Total Knee Arthroplasty NCT04247646	Scripps Health	N/A
Completed	Pharmacokinetics of Morphine and Oxycodone in Frail Elderly Undergoing Cardiac Surgery NCT04696445	St. Antonius Hospital	—
Completed	Opioid Prescription After Cesarean Trial NCT04296396	The George Washington University Biostatistics Center	Phase 3
Completed	Variation in Opioid Prescribing and Use for Acute Pain in Diverse Populations NCT04509115	Yale University	—
Completed	Opioid Laws and Pediatric Use NCT04543227	Nationwide Children's Hospital	—
Completed	Appropriate Opioid Quantities for Acute Pain - Pharmacist Study NCT04484610	Centre for Addiction and Mental Health	Phase 4
Completed	STandard Versus No Opioid Prescription After Prolapse and Anti-INcontinence Surgery Trial NCT04491617	The Cleveland Clinic	N/A
Completed	PRescribing INterventions for Chronic Pain Via the Electronic Health Record Study - Current Opioid-User Popula NCT04601480	University of Minnesota	N/A
Completed	PRescribing INterventions for Chronic Pain Via the Electronic Health Record Study - Opioid-Naive Population NCT04601493	University of Minnesota	N/A
Completed	PRescribing INterventions for Chronic Pain Via the Electronic Health Record Study - Primary Care Providers NCT04601506	University of Minnesota	N/A
Withdrawn	Mobile Health (mHealth) App for Safe Opioid Use NCT04462250	Rutgers, The State University of New Jersey	N/A
Completed	Pain Avoidance Behavior and Its Relation to Risk for Opioid Use in Chronic Pain Patients NCT04603417	The Cleveland Clinic	N/A
Completed	Mindfulness Oriented Recovery Enhancement for Chronic Pain and Opioid Relapse NCT04491968	Rutgers, The State University of New Jersey	N/A

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