NCT06962033

PRIDE III Prison Interventions and HIV Prevention Collaboration

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 300 (estimated)
• Sponsor: Yale University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The primary objective of this research project is to identify barriers to scale-up of Opioid Agonist Therapy (OAT) in the justice systems (prisons and probation) in Tajikistan, Kyrgyzstan, Moldova, and Georgia, and establish a NIATx learning collaborative to scale-up OAT, and analyze scale-up utilizing latent class growth analyses in people who inject drugs (PWID).

Detailed description

Aim 1 consists of the development of NIATx learning collaboratives with prison OAT providers (addiction care specialists or primary care doctors). This aim is an implementation science aim involving the collection of OAT scale-up data from each country's national OAT database, as well as administration of survey to prison narcologists every 6 months. Aim 2 consists of the development of NIATx learning collaboratives with probation and prison officers in Kyrgyzstan, Tajikistan, Moldova, and Georgia. Investigators will collect OAT scale-up data from each member country's national OAT database, and administer a survey to probation officers every 6 months. Investigators will also observe and interview probation clients and staff using ethnographic methods.

Conditions

• Hiv
• Opioid Use

Interventions

Type	Name	Description
BEHAVIORAL	Opioid Agonist Therapy	Opioid Agonist Therapy (OAT) as HIV prevention

Timeline

• Start date: 2024-11-05
• Primary completion: 2028-12-01
• Completion: 2028-12-01
• First posted: 2025-05-08
• Last updated: 2025-05-11

Locations

5 sites across 5 countries: United States, Georgia, Kyrgyzstan, Moldova, Tajikistan