NCT05548582

Reduced Opioid Prescription After Laparoscopic Hysterectomy

A Randomized Controlled Trial to Study Reduced Opioid Prescription After Laparoscopic Hysterectomy

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (estimated)
• Sponsor: Johns Hopkins University · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Given the nationwide epidemic of opioid use and abuse (in part due to over prescription), this study aims at addressing the need for opioid prescription after laparoscopic hysterectomy.

Detailed description

Currently, there is a nationwide epidemic of opioid abuse and overdose deaths. One source of excess opioids is overprescribing in the postoperative period. Given the increasing opioid abuse and over-prescription post-operatively, an effort must be made to determine whether non-opioid multimodal medications are adequate in treating postoperative pain after laparoscopic hysterectomy and would not increase the need for additional prescriptions or unscheduled patient contacts. This study aims to find the optimal prescriptions for pain after laparoscopic hysterectomy in an attempt to eliminate opioid use.

Conditions

• Pain, Postoperative
• Opioid Misuse
• Opioid Use
• Pain

Interventions

Type	Name	Description
DRUG	OxyCODONE 5 mg Oral Tablet	No opioid prescription after laparoscopic hysterectomy
DRUG	Acetaminophen 500 mg Tab	Standard prescription
DRUG	Ibuprofen 600 mg	Standard prescription

Timeline

• Start date: 2023-01-12
• Primary completion: 2026-12-31
• Completion: 2026-12-31
• First posted: 2022-09-21
• Last updated: 2026-01-12

Locations

1 site across 1 country: United States