NCT04550715

Prevention Interventions for Opioid Misuse

Optimized Interventions to Prevent Opioid Use Disorder Among Adolescents and Young Adults in the Emergency Department

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,155 (actual)
• Sponsor: University of Michigan · Academic / Other
• Sex: All
• Age: 16 Years – 30 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to develop and test innovative interventions to prevent the development of opioid misuse and opioid use disorders among older adolescents and young adults (AYA; ages 16-30) who use opioids, which will be initiated from a health care visit in the emergency department and extended post discharge via a telehealth approach. This study will have significant impact by identifying optimal, cost-effective opioid prevention strategies to sustain outcomes among AYAs.

Conditions

• Opioid Use

Interventions

Type	Name	Description
BEHAVIORAL	Brief intervention (BI)	A remote brief intervention delivered by health coaches that uses Motivational Interviewing to address opioid misuse and risk factors. Remote health coaches use a web-based clinician support guide to maintain fidelity, while tailoring the session to unique participant factors.
BEHAVIORAL	Portal	Remote health coaches will push tailored messages to participants over a 4-week period. The messages will use Motivational Interviewing strategies. The messages are designed to elicit a response from the participant. Health coaches will also respond to participant replies consistent with Motivational Interviewing over a course of 4 weeks.
BEHAVIORAL	Enhanced Usual Care (EUC)	The brochure covers educational topics like opioid storage and disposal and overdose prevention, as well as resources such as naloxone, suicide hotlines, mental health, and substance use treatment. It will be available online and in print.

Timeline

• Start date: 2021-01-04
• Primary completion: 2025-04-14
• Completion: 2025-04-14
• First posted: 2020-09-16
• Last updated: 2026-01-29

Locations

1 site across 1 country: United States