NCT04740099

Surviving Opioid Overdose With Naloxone Education and Resuscitation Trial (SOONER)

Surviving Opioid Overdose With Naloxone Education and Resuscitation Trial (SOONER): Randomized Trial and Embedded Qualitative Study to Compare the Effectiveness of point-of Care Overdose Education and Naloxone Distribution Versus Referral to an Existing Community Program in the Management of Simulated Opioid-associated Resuscitative Emergencies.

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Unity Health Toronto · Academic / Other
• Sex: All
• Age: 16 Years
• Healthy volunteers: Accepted

Summary

Among people at risk of opioid overdose and receiving care in an academic emergency department, family practice, opioid substitution clinic or general inpatient units, does brief opioid overdose resuscitation training and naloxone distribution reduce resuscitation failures in a simulated overdose even, in comparison with standard-of-care referral to a local OEND program, within 14 days post-intervention? Can an integrated participant recruitment and retention strategy recruit approximately 28 eligible participants within 4 weeks and maintain less than 50% attrition rates in the context of a randomized trial on point-of-care OEND and simulated overdose resuscitation performance in family practice, emergency department, and addictions settings?

Conditions

• Opioid Use
• Opioid-Related Disorders
• Opioid Withdrawal
• Opioid Overdose
• Education
• Resusitation

Interventions

Type	Name	Description
OTHER	SOONER Video & Kit	A brief animated video including basic instructions for opioid overdose response accompanied by a Naloxone kit with an info graphic.
OTHER	Standard of Care	A handout including a map and list of locations offering this service.

Timeline

• Start date: 2021-12-01
• Primary completion: 2022-12-01
• Completion: 2023-03-01
• First posted: 2021-02-05
• Last updated: 2022-10-03

Locations

1 site across 1 country: Canada