NCT05485012

Reinforcing Effects of Marijuana and Opioids

Modulation of Drug Intake: Evaluation of Opioid and Cannabinoid Interactions on Drug Self-Administration

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 8 (actual)
• Sponsor: Shanna Babalonis, PhD · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The primary goals of this study are to examine 1) marijuana modulation of oxycodone self-administration and 2) oxycodone modulation of marijuana self-administration, under controlled conditions and across a range of doses for each drug.

Conditions

• Marijuana Use
• Opioid Use

Interventions

Type	Name	Description
DRUG	Marijuana	Double-blind administration of marijuana
DRUG	Opioid	Double-blind administration of an opioid agonist

Timeline

• Start date: 2023-08-03
• Primary completion: 2025-03-27
• Completion: 2025-03-27
• First posted: 2022-08-02
• Last updated: 2026-04-15
• Results posted: 2026-04-15

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study