Hyperalgesia

72 registered clinical trials studyying Hyperalgesia — 3 currently recruiting.

Status	Trial	Sponsor	Phase
Recruiting	Investigation on the Status Quo of Hyperalgesia in Patients After Thoracoscopic Operation and Study on the Eff NCT06790914	Fujian Medical University Union Hospital	N/A
Recruiting	STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancrea NCT05603702	Indiana University	Phase 1
Terminated	Effect of Ultra-low Dose Naloxone on Remifentanil-Induced Hyperalgesia NCT03066739	University of California, Irvine	Phase 2
Recruiting	Electroacupuncture Pain Treatment, Mechanical Hyperalgesia, Quality of Life & Expression of Mu+ B Cells in Fib NCT05357157	University of Crete	—
Unknown	Safety and Efficacy Evaluation of S (+) - Ketamine in Children NCT04834427	Chinese PLA General Hospital	Phase 4
Suspended	Impact of Repeatedly-Administered THC-cannabis on Experimental Pain and Abuse Liability in Humans NCT04596644	New York State Psychiatric Institute	Phase 2
Completed	Repeated Cannabis Administration on Experimental Pain and Abuse Liability NCT04576507	New York State Psychiatric Institute	Phase 2
Completed	Evaluation of a Patient-Centred, Multidisciplinary Opioid Tapering Program for Individuals With Chronic Non-Ca NCT04902547	University of Manitoba	N/A
Completed	Reducing Nocebo Effects on Pressure Pain NCT05284383	Leiden University	N/A
Completed	ERECTOR SPINE PLANE BLOCK VERSUS LOCAL INFILTRATION ANAESTHESIA FOR TRANSFORAMINAL PERCUTANEOUS ENDOSCOPIC DIS NCT05483647	Lviv National Medical University	N/A
Unknown	Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Sp NCT04697498	Lviv National Medical University	N/A
Completed	Pain Response to Cannabidiol in Opioid-induced Hyperalgesia, Acute Nociceptive Pain and Allodynia By Using a M NCT04059978	University Hospital, Basel, Switzerland	N/A
Unknown	Central Sensitisation and Postoperative Pain NCT04220697	Université Catholique de Louvain	N/A
Completed	Electrophysiological Correlates of Nocebo Effects on Pain NCT04199858	Leiden University Medical Center	N/A
Completed	Pain-related Fear as a Facilitator of Nocebo Hyperalgesia NCT04197154	Leiden University Medical Center	N/A
Completed	Pain Response to Cannabidiol in Induced Acute Nociceptive Pain, Allodynia and Hyperalgesia By Using a Model Mi NCT03985995	University Hospital, Basel, Switzerland	N/A
Unknown	Exercise-induced Ischemia and the Influence of Pain Modulation in a Nerve Growth Factor (NGF) Model NCT03844243	Aalborg University	EARLY_Phase 1
Completed	Gabapentin Pretreatment for Staged Bilateral Cataract Operations NCT03826615	Seoul National University Hospital	N/A
Completed	The Role of Learning in Nocebo Hyperalgesia NCT03793790	Leiden University Medical Center	N/A
Withdrawn	Pilot Study to Compare Topical Voriconazole to Placebo as a Pain Reducing Agent NCT02689713	Kenneth Hargreaves	Phase 2
Completed	Hyperalgesia, Persistent Pain, and Fentanyl Dosing in On-Pump Coronary Artery Bypass Grafting NCT03450161	University Hospital, Ghent	Phase 4
Completed	Drip-infusion of Remifentanil for RIH NCT04387097	Tri-Service General Hospital	—
Completed	Interaction Between NGF and Acute Exercise-induced Ischemia NCT03470038	Aalborg University	EARLY_Phase 1
Completed	Cortical Neuroplasticity by Muscle Pain of Pain-induced Plasticity NCT03354624	Aalborg University	N/A
Completed	Effect of High-dose Naloxone Following Third Molar Extraction NCT02976337	mads u werner	Phase 2
Unknown	Prevention of Hyperalgesia With Epidural Morphine NCT03225690	Cukurova University	Phase 4
Completed	Spread of Muscle Hyperalgesia and Pain in a Low Dose NGF-induced Pain Model NCT03217942	Aalborg University	EARLY_Phase 1
Unknown	The Relationship Between Saliva β-endorphins Levels, Cold Pressor Test and Perception of Pain in Oral Surgery NCT03164161	Lithuanian University of Health Sciences	N/A
Completed	Administration of Acetazolamide to Prevent Remifentanil Induced Hyperalgesia NCT02992938	University of Chile	Phase 4
Completed	DNA Methylation and Perioperative Pain Treatment NCT02938455	University of Bologna	—
Unknown	Opioid Induced Hyperalgesia (OIH) Modulation With Propranolol NCT02934763	Pontificia Universidad Catolica de Chile	Phase 4
Completed	Effect of High-dose Naloxone Infusion on Pain and Hyperalgesia in Patients Following Groin-Hernia Repair. NCT01992146	Rigshospitalet, Denmark	Phase 2
Completed	Dextromethorphan Effect on Central Sensitization to Pain in Healthy Volunteers NCT02596360	University Hospital, Clermont-Ferrand	Phase 1
Completed	Preoperative Intraarticular Injection of Methylprednisolone in Patients Scheduled for Total Knee-arthroplasty NCT02253966	Rigshospitalet, Denmark	Phase 2
Completed	L-menthol as a Topical Counter-irritant to TRPA1-induced Neurogenic Inflammation and Pain NCT02653703	Aalborg University	N/A
Completed	Prevention of Remifentanil-induced Postoperative Hyperalgesia With Intravenous Ibuprofen NCT02243254	Seoul National University Hospital	N/A
Unknown	Effect of Gabapentin on Pain of the Second Cataract Surgery NCT02127853	Seoul National University Hospital	Phase 4
Completed	Fenobam on Heat/Capsaicin Induced Hyperalgesia in Healthy Volunteers NCT01981395	Laura Cavallone	Phase 1
Completed	Analgesic Effect of Oxytocin Receptor Modulation NCT01918475	Insel Gruppe AG, University Hospital Bern	N/A
Completed	Effect of High Dose Naloxone on Secondary Hyperalgesia NCT01935206	Rigshospitalet, Denmark	Phase 1
Completed	Hypoalgesic Effects Neural Mobilization Techniques NCT02011477	Josue Fernandez Carnero	EARLY_Phase 1
Terminated	Evaluation of the Antihyperalgesic Effect of Tapentadol in Two Human Experimental Models NCT01615510	University Hospital Schleswig-Holstein	Phase 1
Completed	Opioid-induced Hyperalgesia After Remifentanil Infusion NCT01702389	Oslo University Hospital	Phase 4
Completed	IV Acetaminophen as an Adjunct Analgesic in Cardiac Surgery NCT01544062	University of Washington	Phase 4
Completed	Hyperbaric Oxygen Therapy Attenuates Central Sensitization Induced by a Thermal Injury in Human Volunteers (HB NCT02025686	Per Rotbøll Nielsen	N/A
Completed	Hyperalgesia and Pain NCT01581450	Air Liquide Santé International	Phase 1
Completed	Preventing Pain After Heart Surgery NCT01480765	Barts & The London NHS Trust	Phase 4
Completed	Evaluation of the Effect of Ketamine on Remifentanil-induced Hyperalgesia NCT01301079	Federal University of São Paulo	Phase 3
Unknown	Effect of Propofol on Remifentanil-induced Postoperative Hyperalgesia in Patients Undergoing Thyroid Surgery NCT01189721	Gangnam Severance Hospital	Phase 4
Completed	Perioperative Opioid-induced Hyperalgesia and Its Prevention With Ketamine and Methadone NCT01594047	Fondazione IRCCS Istituto Nazionale dei Tumori, Milano	N/A
Completed	Effect of Intraoperative Magnesium on Remifentanil-induced Postoperative Hyperalgesia After Thyroidectomy NCT01025245	Yonsei University	Phase 4
Unknown	The Effect of High-dose Remifentanil on Established Sunburn-induced Hyperalgesia in Human Volunteers (HighDose NCT01015482	Medical University of Vienna	Phase 4
Unknown	The Effect of High-dose Remifentanil on Established Capsaicin-induced Hyperalgesia in Human Volunteers NCT00886106	Medical University of Vienna	Phase 4
Terminated	Local Anesthetic Infusion and Sternotomy NCT00802048	University Hospital, Bordeaux	Phase 3
Completed	Study on the Development of Opioid Induced Hyperalgesia (OIH) After Exposure to Alfentanil NCT00991809	Johns Hopkins University	N/A
Completed	Study on the Effect of a Beta Blocker on Increased Sensitivity to Pain in Humans Caused by Opioids NCT01222091	Stanford University	Phase 2
Completed	Local Anesthetic Infiltration to Prevent Postoperative Pain After Lumbar Surgery NCT00825422	University Hospital, Bordeaux	Phase 3
Unknown	The Effect of Remifentanil on Established Sunburn-induced Hyperalgesia in Human Volunteers NCT00811837	Medical University of Vienna	Phase 4
Unknown	The Effect of Remifentanil on Established Capsaicin-Induced Hyperalgesia in Human Volunteers NCT00789386	Medical University of Vienna	Phase 4
Completed	Effect of Ketamine on Opioid-Induced Hyperalgesia NCT00833755	Massachusetts General Hospital	N/A
Completed	Pain Medicine for Wound Care Procedures NCT00701909	University of California, San Francisco	Phase 3
Completed	A Safety Tolerance and Experimental Hyperalgesia Study of Oral NGX426 in Healthy Male Voluneteers NCT00832546	TorreyPines Therapeutics	Phase 1
Completed	Effects of Nefopam on Hyperalgesia After Cardiac Surgery NCT00413257	University Hospital, Bordeaux	Phase 2 / Phase 3
Completed	A Study Of GSK189254 And Duloxetine In The Electrical Hyperalgesia Model Of Healthy Volunteers NCT00387413	GlaxoSmithKline	Phase 1
Completed	Dextromethorphan, Gabapentin, and Oxycodone to Treat Opioid-Induced Hyperalgesia NCT00218374	National Institute on Drug Abuse (NIDA)	N/A
Completed	Effects of Lidocaine Patch on Intradermal Capsaicin Induced Pain and Hyperalgesia NCT00373893	University of California, San Diego	Phase 1
Completed	Effect of Valdecoxib Pretreatment on Pain and Secondary Hyperalgesia in Healthy Volunteers NCT00260325	Penn State University	Phase 4
Unknown	Effects of N-Methyl-D-Aspartate (NMDA)-Receptor Antagonism on Hyperalgesia, Opioid Use, and Pain After Radical NCT00188383	University Health Network, Toronto	Phase 1 / Phase 2
Completed	GW406381 In Patients With Peripheral Nerve Injury NCT00279032	GlaxoSmithKline	Phase 1
Completed	Analgesic Efficacy of Smoked Cannabis NCT00241579	Center for Medicinal Cannabis Research	Phase 1 / Phase 2
Completed	Influence of Genetics in Pain Sensitivity NCT00001956	National Institute of Dental and Craniofacial Research (NIDCR)	Phase 2
Completed	Positron Emission Tomography to Measure Pain and Pain Control NCT00001307	National Institute of Dental and Craniofacial Research (NIDCR)	—