NCT02127853

Effect of Gabapentin on Pain of the Second Cataract Surgery

The Effect of Pretreated Gabapentin on Hyeralgesia Occurring in the Second Operation in Staged Bilateral Cataract Surgery

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 70 (estimated)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 80 Years
• Healthy volunteers: Accepted

Summary

Gabapentin pretreatment may reduce hyperalgesia occurring at the second surgery in serial, bilateral cataract surgery.

Detailed description

Hyperalgesia occurring at the second operation in bilateral eye surgery is well known, and mechanism of central sensitization might be involved. Gabapentin is known to lower the effect of central sensitization, and its effect on acute postoperative pain has been reported. Therefore, pretreatment of gabapentin after first operation may reduce the pain at second operation.

Conditions

• Hyperalgesia

Interventions

Type	Name	Description
DRUG	gabapentin	100 mg tid of gabapentin is prescribed to the patient for 1 week after the first eye surgery
DRUG	placebo	the same regimen of placebo drug is prescribed to the patient for 1 week after the first eye surgery

Timeline

• Start date: 2014-07-01
• Primary completion: 2016-02-01
• Completion: 2016-02-01
• First posted: 2014-05-01
• Last updated: 2015-05-12

Locations

1 site across 1 country: South Korea