Clinical Trials Directory

Trials / Conditions / Hemophilia A

Hemophilia A

364 registered clinical trials studyying Hemophilia A46 currently recruiting.

StatusTrialSponsorPhase
RecruitingA Clinical Study to Evaluate the Effects of NXT007 Compared to Factor VIII Prophylaxis in Participants With He
NCT07416526
Hoffmann-La RochePhase 3
Not Yet RecruitingLiver Biopsy Following Gene Therapy For Hemophilia
NCT05932914
St. Jude Children's Research Hospital
RecruitingA Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophili
NCT07416604
Hoffmann-La RochePhase 3
Not Yet RecruitingAn Observational Study to Learn More About How Well Damoctocog Alfa Pegol Works in Previously Treated Children
NCT07088458
Bayer
RecruitingNuwiq Dosing and Outcomes In the ManagEment of Women/Girls With Haemophilia A Needing FVIII Treatment for Surg
NCT05936580
OctapharmaPhase 4
Not Yet RecruitingA Gene Therapy Study of SPK-8011QQ in Adults With Severe or Moderately Severe Hemophilia A
NCT07226206
Hoffmann-La RochePhase 1 / Phase 2
RecruitingSAFE Study: Safety of aPCC Following Emicizumab Prophylaxis
NCT04563520
Emory UniversityPhase 3
RecruitingJoint Health, Balance and Quality of Life in Adults With Hemophilia A
NCT07523399
Yuzuncu Yil University
Not Yet RecruitingEffects of Emicizumab Treatment in Patients With Hemophilia A
NCT07190118
Hasan Kalyoncu University
RecruitingLong-term Anticoagulation in a Patient With Severe Hemophilia A
NCT07314983
University Hospital, Strasbourg, France
Not Yet RecruitingLow Dose Emicizumab vs Low Dose Factor VIII in Prophylaxis in Hemophilia A Patients
NCT06938659
Dhaka Medical CollegePhase 2 / Phase 3
RecruitingLong-term Study Evaluating Joint Health in People With Haemophilia A Receiving Real-world Prophylactic Treatme
NCT06940830
Swedish Orphan BiovitrumPhase 4
RecruitingTo Evaluate the Clinical Study of GS1191-0445 Injection in the Treatment of Hemophilia A
NCT06833983
Gritgen Therapeutics Co., Ltd.Phase 3
WithdrawnPatient Interview Study to Explore the Impact of Gene Therapy in Hemophilia A & B
NCT06634836
Pfizer
RecruitingPharmacokinetic Comparison of Efanesoctocog Alfa vs Other EHL-rFVIII Products in Participants With Severe Haem
NCT06579144
Swedish Orphan BiovitrumPhase 1
RecruitingManual Therapy in Hemophilic Arthropathy of the Ankle
NCT06816056
Investigación en Hemofilia y FisioterapiaN/A
Not Yet RecruitingSynovial Proliferation on Routine Ultrasound: Active or Inactive?
NCT06809972
Van Creveldkliniek
TerminatedGoal Attainment and Physical Activity in People With Hemophilia A
NCT06530030
Sanofi
RecruitingA Study to Evaluate Impact of Efanesoctocog Alfa on Long-term Joint Health in Participants With Hemophilia A i
NCT06684314
Sanofi
RecruitingLongitudinal Cohort of Thrombosis and Hemostasis Diseases
NCT06727669
Peking University People's Hospital
UnknownEffect of Kinetic Chain Exercises on Muscle Strength, Joint Position Sense and Quality of Life in Children wit
NCT06649175
Cairo UniversityN/A
RecruitingMeasurement Properties in People with Hemophilia
NCT06565481
University of ZurichN/A
RecruitingHome Monitoring in Hemophilia a
NCT06702579
Radboud University Medical Center
Enrolling By InvitationATHNdataset Registry
NCT06820515
American Thrombosis and Hemostasis Network
RecruitingDevelopment of Non-Invasive Prenatal Diagnosis for Single Gene Disorders
NCT06147414
Assistance Publique - Hôpitaux de Paris
Not Yet RecruitingHematopoietic Stem Cell Transplantation Gene Therapy for Treatment of Severe Hemophilia A
NCT04418414
Expression Therapeutics, LLCPhase 1
CompletedCase and Use Scenario Study to Gain Knowledge on the User Needs for a Medical Device for Hemophilia a Monitori
NCT06369740
Enzyre B.V.
CompletedReal World Use of Emicizumab in Infants and Children Ages 0-3 Years With Hemophilia A
NCT05248594
Montefiore Medical Center
RecruitingHemophilia A Research Program
NCT07414511
University of Washington
TerminatedThe Long-term Safety and Efficacy of SerpinPC in Subjects with Hemophilia Who Completed a Sponsored SerpinPC C
NCT06568302
ApcinteX LtdPhase 3
SuspendedVersion Testing of EnzySystem Version A for Hemophilia A
NCT06273865
Radboud University Medical Center
RecruitingA Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (P
NCT06349473
Equilibra Bioscience LLCPhase 1
UnknownA Clinical Study of Recombinant Human Coagulation Factor VIII for Injection in Patients With Severe Hemophilia
NCT06297655
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.Phase 3
Enrolling By InvitationCartilage Biomarkers and HEAD-US Score in Severe Hemophilia A Patients Receiving FVIII Prophylaxis
NCT06816953
Chulalongkorn UniversityN/A
CompletedEVALUATION of the OVERALL HAEMOSTATIC CAPACITY of MIM8 with GLOBAL HAEMOSTASIS ASSAYS and FIBRIN CLOT ULTRASTR
NCT06212505
Hospices Civils de Lyon
CompletedReal-life Clinical FEIBA Samples Measured Using the Version A of the HemA EnzySystem
NCT06357572
Enzyre B.V.
WithdrawnStudy of a Gene Therapy Treatment for Hemophilia A
NCT06297486
Spark Therapeutics, Inc.Phase 3
RecruitingA Study to Test a Medicine (Fitusiran) for Preventing Bleeds in People With Severe Hemophilia Who Previously R
NCT06145373
SanofiPhase 4
CompletedEffects of Ultrasound and Infrared on Joint Pain and Movement in Hemophilia A Patients.
NCT07116993
Danyal AhmadN/A
RecruitingA Study to Learn More About the Safety of Damoctocog-alfa-pegol When Used in Routine Medical Care in Korean Pa
NCT06222697
Bayer
RecruitingSafety and Efficacy Study of NGGT003 in Hemophilia A Patients
NCT06238908
Institute of Hematology & Blood Diseases Hospital, ChinaEARLY_Phase 1
RecruitingEvaluation of the Safety and Efficacy of Hemophilia A Gene Therapy Drugs
NCT06111638
Shanghai Xinzhi BioMed Co., Ltd.Phase 2 / Phase 3
Active Not RecruitingPhase 3 Study for Efficacy and Safety Outcomes Data in Japanese Patients With Severe Hemophilia A
NCT06224907
BioMarin PharmaceuticalPhase 3
UnknownHealth-Related Quality of Life Outcomes and Bleeding Rates Among Patients With Severe Hemophilia A on Emicizum
NCT06104826
Newark Beth Israel Medical Center
CompletedComparison of Efficiency of Closed Kinetic Chain Exercises Versus Proprioceptive Exercises Patient With Hemoph
NCT05879549
Bahçeşehir UniversityN/A
UnknownAlterations in Coagulation Factor Levels in Patients With End Stage Liver Disease
NCT06014320
Stanford University
RecruitingA Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of NXT007 in Pe
NCT05987449
Hoffmann-La RochePhase 1 / Phase 2
UnknownPatterns of Hemophilia Care in Assiut Children Patients
NCT05980377
Assiut University
TerminatedAn 18-month Low-interventional Study to Assess Joint Health in Haemophilia A and B Patients on Prophylaxis Wit
NCT05856266
Swedish Orphan BiovitrumPhase 4
RecruitingPrevention of Bleeding in Patients With Moderate and Severe Hemophilia A Playing Sports: A Comparison Between
NCT05022459
Wayne State University
UnknownViscoelastic Properties of Lower Extremity Muscles in Patients With Hemophilia
NCT05981313
Hasan Kalyoncu University
CompletedStudy of TU7710 in Warfarin Anti-coagulated Healthy Male Subjects
NCT06025552
TiumBio Co., Ltd.Phase 1
Active Not RecruitingA Trial of the Safety and Efficacy of Single-Dose Administration of ANB-010 in Subjects With Hemophilia A
NCT06185335
BiocadPhase 1 / Phase 2
UnknownImpact of Emicizumab on Activated Clotting Time Using the i-STAT Alinity Analyzer
NCT05856903
University Hospital, Grenoble
TerminatedThe Efficacy and Safety of SerpinPC in Participants with Severe Hemophilia a or Moderately Severe to Severe He
NCT05789524
ApcinteX LtdPhase 2
Active Not RecruitingA Study to Evaluate Impact of Efanesoctocog Alfa on Long-term Joint Health in Participants With Hemophilia A
NCT05911763
Sanofi
CompletedA Study of Adynovate in Previously Treated Chinese Teenagers and Adults With Severe Hemophilia A
NCT05707351
TakedaPhase 3
TerminatedA Prospective Study Evaluating Seroprevalence and Seroconversion of Antibodies Against Adeno-associated Virus
NCT05580692
BioMarin PharmaceuticalN/A
TerminatedA Study to Learn More About Treatment With Damoctocog Alfa Pegol, How it is Used in Every Day Practice ("Real-
NCT05395858
Bayer
CompletedSatisfaction Regarding the Dispensing of Emicizumab (HEMLIBRA®) for Patients With Haemophilia A in France
NCT05450640
Hospices Civils de Lyon
Enrolling By InvitationA Long-Term Follow-Up Study in Severe Hemophilia A Subjects Who Received BMN 270 in a Prior BioMarin Clinical
NCT05768386
BioMarin Pharmaceutical
Active Not RecruitingAn Observational Study Called JOIHA to Learn More About How Well the Treatment With Jivi Works to Prevent Prob
NCT05643560
Bayer
RecruitingSafety and Effectiveness of Giroctocogene Fitelparvovec or Fidanacogene Elaparvovec in Patients With Hemophili
NCT05568719
PfizerPhase 3
UnknownNeutrophil-to-lymphocyte and Platelet-to-lymphocyte Ratio in Predicting the Incidence of Nausea and Vomiting
NCT05636163
Qianfoshan Hospital
RecruitingA Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia B
NCT05611801
PfizerPhase 3
TerminatedHemophilia Non-Interventional Study Prior to SerpinPC Intervention (PRESent-5)
NCT05605678
ApcinteX Ltd
UnknownEmotions in the Communication and Relationship Styles of Parents With Hemophilic Children.
NCT05754619
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
RecruitingThe Efficacy and Safety of ZS802 in Chinese Hemophilia A Patients.
NCT05523128
Institute of Hematology & Blood Diseases Hospital, ChinaN/A
CompletedBaby Detect : Genomic Newborn Screening
NCT05687474
Centre Hospitalier Universitaire de Liege
RecruitingASC618 Gene Therapy in Hemophilia A Patients
NCT04676048
ASC TherapeuticsPhase 1 / Phase 2
CompletedFactor IX as Adjunctive Therapy to Emicizumab (EMIX)
NCT05281718
Tulane UniversityEARLY_Phase 1
CompletedProphylaxis Regimen for Hemophilia A Patients
NCT05036278
BayerPhase 4
RecruitingA Study of FVIII Gene Therapy for Hemophilia A
NCT05454774
Institute of Hematology & Blood Diseases Hospital, ChinaEARLY_Phase 1
CompletedEvaluation of the Training Program for Community Pharmacists for Dispensing Emicizumab (HEMLIBRA®) in France
NCT05449197
Hospices Civils de Lyon
UnknownValidation and Reliability of the CHO-KLAT in Turkish
NCT05439642
Yuzuncu Yil UniversityN/A
UnknownStudy of Surgical Practices in Patients With Haemophilia A or B Treated With an Extended Half-life Recombinant
NCT06158334
Hospices Civils de Lyon
UnknownClinical Study of Recombinant Human Activated Coagulation Factor VII for Injection in Patients With Hemophilia
NCT05487976
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.Phase 3
UnknownUPLC-MS/MS Monitoring of Emicizumab Therapy
NCT04472169
University Hospital, Lille
CompletedHematopoietic Stem Cell Transplantation Gene Therapy for Treatment of Severe Hemophilia A
NCT05265767
Christian Medical College, Vellore, IndiaPhase 1
CompletedA Study to Learn How Safe the Study Treatment BAY94-9027 is and How it Affects the Body in Previously Treated
NCT05147662
BayerPhase 3
CompletedIntensive Replacement Treatment in Haemophilia Patients With Synovitis
NCT04784988
Federico II UniversityPhase 4
WithdrawnEmicizumab PUPs and Nuwiq ITI Study
NCT04030052
Emory UniversityPhase 3
CompletedA Study of ADVATE in People With Hemophilia A in India
NCT04985682
Baxalta now part of ShirePhase 4
CompletedA Study in Children, Teenagers and Adults With Severe Hemophilia A Who Switched From Other Factor VIII Treatme
NCT04876365
Takeda
UnknownAcquired Hemophilia A and Autoimmunity. Study of Lymphocyte Populations and Myeloid-Derived Suppressor Cells
NCT04805021
Nantes University Hospital
RecruitingOpen-Label Extension Study of Marstacimab in Hemophilia Participants With or Without Inhibitors
NCT05145127
PfizerPhase 3
UnknownPre-clinical Models for Mesenchymal Stem Cell Therapy in Hemophilic Arthropathy
NCT05187936
University Hospital, Montpellier
CompletedA Study of Standard and Individualized Prophylactic Treatment With Advate in Men and Boys With Severe Hemophil
NCT04953000
Takeda
CompletedPharmacokinetic Assessment of Standard Half-Life (SHL) FVIII, Extended Half-Life (EHL) FVIII, and Efanesoctoco
NCT05042440
SanofiPhase 1
CompletedOutcomes of Prophylaxis With Emicizumab in Children With Severe Hemophilia A in Ivory Coast
NCT05279924
Cliniques universitaires Saint-Luc- Université Catholique de LouvainN/A
CompletedA Study of TAK-660 in Surgical Procedures for People With Hemophilia A.
NCT04941898
Takeda
CompletedA Study to Evaluate the Safety and Pharmacokinetic of Recombinant Human Coagulation Factor VIII ,Fc Fusion Pro
NCT05251090
Jiangsu Gensciences lnc.Phase 1
CompletedStudy to Learn More About the Physical Activity Level of Patients Suffering From Hemophilia A Treated With Dam
NCT04091386
Bayer
CompletedVitamin K Antagonist Versus Direct Oral Anticoagulant Treatments in Hemophilia
NCT05804734
Groupe Maladies hémorragiques de Bretagne
Active Not RecruitingStudy to Learn More About the Safety of Drug Jivi Over a Long Period of Time in Previously Treated Patients Wi
NCT04461639
Bayer
CompletedPsychometric Validation of the Hemophilia Functional Ability Scoring Tool (Hemo-FAST)
NCT04731701
Swedish Orphan Biovitrum
CompletedPhase III Expansion Trial for Determining the Safety and Efficacy of Recombinant Human Coagulation Factor VIII
NCT04845399
Zhengzhou Gensciences IncPhase 3
WithdrawnPOCUS: Hemostatic Potential and Joint Health in Patients With Severe Hemophilia A on Novel Replacement Therapi
NCT04690322
University of Texas Southwestern Medical CenterPhase 4
CompletedHealth Related Quality of Life of Youth and Young Adults With Haemophilia A
NCT04728217
The League of Clinical Research, RussiaPhase 4
RecruitingGene Therapy for Chinese Hemophilia A
NCT04728841
Institute of Hematology & Blood Diseases Hospital, ChinaN/A
Active Not RecruitingLong-term Safety and Efficacy of Efanesoctocog Alfa (BIVV001) in Previously Treated Patients With Hemophilia A
NCT04644575
Bioverativ, a Sanofi companyPhase 3
CompletedSafety, Efficacy and PK of BIVV001 in Pediatric Patients With Hemophilia A
NCT04759131
Bioverativ, a Sanofi companyPhase 3
UnknownClinical and Health-related Outcome of rFVIIIFc Prophylaxis
NCT04583930
Prof. Dr. Dr. Thomas Hilberg
WithdrawnMedication Adherence and Non-adherence in Adults With Rare Disease
NCT04541875
Xperiome
CompletedBT200 in Hereditary Bleeding Disorders
NCT04677803
Medical University of ViennaPhase 2
CompletedStudy to Evaluate the Efficacy and Safety of Valoctocogene Roxaparvovec, With Prophylactic Steroids in Hemophi
NCT04323098
BioMarin PharmaceuticalPhase 3
RecruitingNational Longitudinal Cohort of Hematological Diseases
NCT04645199
Institute of Hematology & Blood Diseases Hospital, China
CompletedAn Open Label Study to Determine the Safety and Efficacy of Recombinant Human Coagulation Factor VIII-Fc Fusio
NCT04456387
Zhengzhou Gensciences IncPhase 3
TerminatedSafety & Efficacy of Encapsulated Allogeneic FVIII Cell Therapy in Haemophilia A
NCT04541628
Eli Lilly and CompanyPhase 1 / Phase 2
CompletedA Post Approval Commitment Study to Gain More Information on How Safe and Effective KOVALTRY is in Chinese Chi
NCT04565236
BayerPhase 4
UnknownPreventing Inhibitor Recurrence Indefinitely
NCT04621916
Children's Hospital Los AngelesPhase 4
UnknownPulsed Electromagentic Field in Haemophilia
NCT04590456
Delta University for Science and TechnologyN/A
CompletedA Study to Evaluate Seroprevalence and Seroconversion of Antibodies to Adeno-Associated Virus (AAV) in Patient
NCT04560933
BioMarin Pharmaceutical
Active Not RecruitingStudy to Evaluate the Efficacy and Safety of PF-07055480 / Giroctocogene Fitelparvovec Gene Therapy in Moderat
NCT04370054
PfizerPhase 3
Active Not RecruitingA Long-term Study of ADYNOVI/ADYNOVATE in Participants With Haemophilia A
NCT04158934
Baxalta now part of Shire
UnknownLentiviral FVIII Gene Therapy
NCT03217032
Shenzhen Geno-Immune Medical InstitutePhase 1
Active Not RecruitingGene Therapy Trial for Platelet Derived Factor VIII Production in Hemophilia A
NCT03818763
Medical College of WisconsinPhase 1
Active Not RecruitingA 48-Month Study to Evaluate Long-Term Effectiveness of Elocta on Joint Health
NCT04293523
Swedish Orphan Biovitrum
RecruitingTreatment of Hemophilia A Patients With FVIII Inhibitors
NCT04023019
Emory University
CompletedStudy of the Efficacy and Safety PF-06741086 in Adult and Teenage Participants With Severe Hemophilia A or Mod
NCT03938792
PfizerPhase 3
CompletedGaining Insight Into the Complexity of Pain in Patients With Haemophilia
NCT05606640
Universiteit Antwerpen
CompletedA Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of Emicizumab in Participants
NCT04158648
Hoffmann-La RochePhase 3
CompletedMoroctocog Alfa (AF-CC) for Prophylaxis and Treatment of Bleeding Episodes in Previously Treated Hemophilia A
NCT04396639
PfizerPhase 4
CompletedImpact on French Physician's Haemophilia Treatment Management Decision Based on Systematic Joint Examination
NCT04133883
Swedish Orphan BiovitrumN/A
CompletedPhysical Activity and FVIII Elimination: Relevance to Personalized Therapy in Severe Hemophilia A
NCT05752565
Fondazione Policlinico Universitario Agostino Gemelli IRCCSN/A
UnknownPHYSICAL ACTIVITY AND FVIII CLEARANCE: RELEVANCE FOR PERSONALIZED THERAPY IN SEVERE HAEMOPHILIA A (PHYSEMO)
NCT04303936
Catholic University of the Sacred HeartN/A
UnknownSafety,Efficacy and Pharmacokinetics Evaluation of SCT800 in Previously Treated Paediatric Patients With Sever
NCT03947320
Sinocelltech Ltd.Phase 3
Active Not RecruitingEvaluating Effectiveness and Long Term Safety of Damoctocog Alfa Pegol in Patients, Who Have Been Diagnosed Wi
NCT03932201
Bayer
CompletedHandheld Ultrasound (HHUS) for Home Use in Hemophilia
NCT04131920
Washington Institute for Coagulation
CompletedStudy of Coagulation Faction VIIa Variant Marzeptacog Alfa (Activated) in Adult Subjects With Hemophilia
NCT04072237
Catalyst BiosciencesPhase 1
CompletedStudy to Gain More Information on How Safe and Effective Jivi Works in Patients With Severe Hemophilia A (Post
NCT04085458
BayerPhase 4
WithdrawnPatient-reported Outcomes in Subjects Treated With ReFacto AF Routine Prophylaxis
NCT02718677
Pfizer
UnknownAssociation Between Individual Clotting Factor Level Monitoring and the Risk of Bleeding Whilst Physical Activ
NCT04845555
Prof. Dr. Dr. Thomas Hilberg
CompletedThe Safety and Tolerability of SerpinPC in Healthy Men and in Men with Severe Blood Disorders (haemophilia a a
NCT04073498
ApcinteX LtdPhase 1 / Phase 2
CompletedStudy to Compare How the Body Distributes and Excretes the Drugs Jivi (BAY 94-9027) and Adynovi in Patients Wi
NCT04015492
BayerPhase 1
UnknownSafety and Efficacy of Long-term Treatment With SCT800 in Previously Treated Hemophilia A Patients.
NCT03947567
Sinocelltech Ltd.Phase 4
UnknownPersonalized Medicine for Canadians With Hemophilia
NCT03615053
McMaster UniversityN/A
UnknownSafety, Efficacy Evaluation of Recombinant Coagulation Factor VIII Injection in Subjects With Hemophilia A.
NCT04061109
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.Phase 3
UnknownPharmacokinetics Evaluation of Recombinant Coagulation Factor VIII Injection in Subjects With Hemophilia A.
NCT04060836
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.Phase 1
RecruitingEffects of Emicizumab vs. Factor VIII Prophylaxis on Joint and Bone Health in Severe Hemophilia A
NCT04131036
Washington Institute for Coagulation
UnknownA Study to Evaluate the Pharmacokinetics of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for In
NCT03747653
Kaifeng Pharmaceutical (Group) Co., Ltd.
CompletedPost Marketing Surveillance Study for ADYNOVATE in South Korea
NCT03824522
Takeda
CompletedEvaluation of SCT800 in Prophylaxis Therapy on Previous Treated Patients With Severe Hemophilia A
NCT03815318
Sinocelltech Ltd.Phase 3
CompletedLead-in Study to Collect Prospective Efficacy and Safety Data of Current FVIII Prophylaxis Replacement Therapy
NCT03876301
Spark Therapeutics, Inc.
Active Not RecruitingStudy to Test the Safety and How Well Patients With Severe Hemophilia A Respond to Treatment With BAY 2599023
NCT03588299
BayerPhase 1 / Phase 2
Enrolling By InvitationEarly Check: Expanded Screening in Newborns
NCT03655223
RTI International
CompletedATHN 8: Previously Untreated Patients (PUPs) Matter Study
NCT03818529
American Thrombosis and Hemostasis Network
CompletedCharacterizing the Impact and Treatment of Reproductive Tract Bleeding on Women and Post-menarchal Girls With
NCT03834727
Oregon Health and Science University
Active Not RecruitingLong-Term Safety and Efficacy of Spark-Sponsored Gene Therapies in Males With Hemophilia A
NCT03432520
Spark Therapeutics, Inc.
TerminatedAssessing Physician and Hemophilia A Patient Reasons and Expectations for Switching Treatment to Kovaltry & Ji
NCT03603275
Bayer
CompletedExercise Versus DDAVP in Patients With Mild Hemophilia A
NCT03379974
Nationwide Children's HospitalPhase 4
CompletedA Study to Evaluate Prospective Efficacy and Safety Data of Current FIX Prophylaxis Replacement Therapy in Adu
NCT03587116
PfizerPhase 3
TerminatedImmune Tolerance Induction in Haemophilia A Patients Using Wilate or Nuwiq
NCT03344003
Octapharma
TerminatedStudy of Emicizumab Prophylaxis in Participants With Hemophilia A With or Without Inhibitors Undergoing Minor
NCT03361137
Genentech, Inc.Phase 4
UnknownWeb Accessible Population Pharmacokinetics Service - Hemophilia: Sources of Variability
NCT03533504
McMaster University
CompletedEfficacy, Safety, and Pharmacokinetic Study of Prophylactic Emicizumab Versus No Prophylaxis in Hemophilia A P
NCT03315455
Hoffmann-La RochePhase 3
TerminatedGene Therapy Study in Severe Hemophilia A Patients With Antibodies Against AAV5
NCT03520712
BioMarin PharmaceuticalPhase 1 / Phase 2
CompletedSingle-Arm Study To Evaluate The Efficacy and Safety of Valoctocogene Roxaparvovec in Hemophilia A Patients at
NCT03392974
BioMarin PharmaceuticalPhase 3
CompletedA Study to Investigate the Pharmacokinetics, Safety, and Tolerability of Emicizumab in Healthy Chinese Volunte
NCT03380780
Hoffmann-La RochePhase 1
CompletedA Study of Fitusiran (ALN-AT3SC) in Severe Hemophilia A and B Patients Without Inhibitors
NCT03417245
Genzyme, a Sanofi CompanyPhase 3
CompletedA Study of BAX 888 in Male Adults With Severe Hemophilia A
NCT03370172
Baxalta now part of ShirePhase 1 / Phase 2
CompletedEvaluation of Patient and Physician Reported Reasons for Switching Factor VIII Replacement Therapies
NCT03405337
Bayer
CompletedA Study of Fitusiran (ALN-AT3SC) in Severe Hemophilia A and B Patients With Inhibitors
NCT03417102
Genzyme, a Sanofi CompanyPhase 3
RecruitingWorld Bleeding Disorders Registry
NCT03327779
World Federation of Hemophilia
CompletedSingle-Arm Study To Evaluate The Efficacy and Safety of Valoctocogene Roxaparvovec in Hemophilia A Patients (B
NCT03370913
BioMarin PharmaceuticalPhase 3
CompletedBAY94-9027 PK Study Comparing to Another Long Acting Product
NCT03364998
BayerPhase 1
CompletedA Study to Evaluate the Safety and Tolerability of Prophylactic Emicizumab in Hemophilia A Patients With Inhib
NCT03191799
Hoffmann-La RochePhase 3
TerminatedUnderstanding Hemophilia A and B Drug Dosage Administration Patterns
NCT03248141
Pfizer
CompletedStudy of rFVIIIFc for Immune Tolerance Induction (ITI) in Haemophilia A Patients With Inhibitors Who Have Fail
NCT03103542
Swedish Orphan BiovitrumPhase 4
CompletedA Safety, Tolerability, and Pharmacokinetics Study of a Single Intravenous Injection of Recombinant Coagulatio
NCT03205163
Bioverativ, a Sanofi companyPhase 1 / Phase 2
CompletedA Study of Recombinant AAV2/6 Human Factor 8 Gene Therapy SB-525 (PF-07055480) in Subjects With Severe Hemophi
NCT03061201
PfizerPhase 2
CompletedExit Interviews to Assess Impact of Infusion Frequency in Hemophilia A
NCT02971930
Bayer
Active Not RecruitingGene Therapy for Haemophilia A.
NCT03001830
University College, LondonPhase 1 / Phase 2
CompletedGlobal Epidemiologic Study of Preexisting Immunity to AAV in Adults With Severe Hemophilia
NCT03185897
Baxalta now part of Shire
TerminatedINdividualized ITI Based on Fviii(ATE) Protection by VWF
NCT03204539
University of California, DavisPhase 4
CompletedData Registry in Chinese Hemophilia A and B Patients
NCT07101224
Institute of Hematology & Blood Diseases Hospital, China
CompletedEvaluation of a Standardized Protocol for Thrombin Generation Assay
NCT03313531
Lund University
CompletedADYNOVATE Drug Use-Results Survey
NCT03169972
Takeda
CompletedA Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Emicizumab Given Every 4 W
NCT03020160
Hoffmann-La RochePhase 3
CompletedA Gene Transfer Study for Hemophilia A
NCT03003533
Spark Therapeutics, Inc.Phase 1 / Phase 2
RecruitingGerman Pediatric Hemophilia Research Database
NCT02912143
Goethe University
UnknownComparison of Ideal vs. Actual Weight Base Factor Dosing
NCT03286153
BloodworksN/A
TerminatedBAX 802 in CHA With Inhibitors
NCT02895945
Baxalta now part of ShirePhase 3
UnknownUK - EHL Outcomes Registry
NCT02938156
Royal Free Hospital NHS Foundation Trust
CompletedOptimizing the Use of Prophylaxis in Patients With Severe Haemophilia A
NCT03915080
Lund UniversityPhase 4
CompletedProspective, Non-interventional Study to Evaluate the Effectiveness of Elocta Compared to Conventional Factor
NCT02976753
Swedish Orphan Biovitrum
CompletedDrug Use Investigation of Kovaltry in Hemophilia A Patients
NCT02941783
Bayer
CompletedPharmacokinetic Characterization of the Hemophilia A Population in Spain Using myPKFiT®
NCT03006965
Spanish Society of Thrombosis and Haemostasis
UnknownEfficacy and Safety Study of SCT800 for On-demand Treatment With in Patients With Hemophilia A
NCT02921945
Sinocelltech Ltd.Phase 3
CompletedA Clinical Trial to Evaluate Prophylactic Emicizumab Versus no Prophylaxis in Hemophilia A Participants Withou
NCT02847637
Hoffmann-La RochePhase 3
TerminatedThe Hemophilia Ultrasound Project
NCT02807753
University of Miami
UnknownPharmacokinetic Study of SCT800 in Previously Treated Patients With Hemophilia A
NCT02888223
Sinocelltech Ltd.Phase 1
CompletedGAS-Hem Feasibility Study
NCT02674997
Baxalta now part of Shire
UnknownPersonalized Prophylactic Treatment With Advate® in Severe or Moderate Haemophilia A Patients
NCT02622646
Hospital Universitario La Fe
UnknownEvaluate Efficacy and Safety of Recombinant Factor VIII (rFVIII)Treatment of Severe or Moderately Severe Hemop
NCT02930317
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.Phase 3
CompletedA Study of Emicizumab Administered Subcutaneously (SC) in Pediatric Participants With Hemophilia A and Factor
NCT02795767
Hoffmann-La RochePhase 3
WithdrawnImproved Factor VIII Inhibitor Evaluation
NCT02726139
Boston VA Research Institute, Inc.
CompletedExtension at 10 Years of the: "Observational Study Evaluating Efficacy and Costs of Secondary Prophylaxis vs O
NCT02581969
Bayer
CompletedVirtual Reality for Hemophilia
NCT03507582
Nationwide Children's HospitalN/A
CompletedCould Physical Activity Help to Counteract the Blood Haemophilia Disturbance? A Pilot Study.
NCT02851082
University Hospital, ToulouseN/A
UnknownEvaluation of a Simple Pharmacokinetic Tool (myPKFiT™) to Guide Personalized Factor VIII Dosing in Patients Wi
NCT02750085
Victor Blanchette
CompletedBAX 826 Dose-Escalation Safety Study
NCT02716194
Baxalta now part of ShirePhase 1
CompletedTreatment Patterns And Outcomes In Patients Treated With Benefix Or Refacto/Refacto AF - A Swedish Cohort Stud
NCT02740413
Pfizer
CompletedUltrasonography in Hemophilic Joint Disease and Serum Markers
NCT02634918
Northwell Health
CompletedRetrospective Chart Review to Evaluate Safety and Tolerability of ADVATE Among Previously Untreated Patients i
NCT02634723
Baxalta now part of Shire
CompletedPatient Functioning and Well-being, Economic, and Clinical Impact of Hemophilia A and Its Treatment
NCT02396862
Bayer
TerminatedPK Driven Prophylaxis for Hemophilia A
NCT02634424
Assistance Publique - Hôpitaux de ParisN/A
CompletedBAX 855 PK-guided Dosing
NCT02585960
Baxalta now part of ShirePhase 3
CompletedA Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Prophylactic Emicizumab Versus no Prophylaxi
NCT02622321
Hoffmann-La RochePhase 3
CompletedA Study of PEGylated Recombinant Factor VIII (BAX855) in Previously Untreated Young Children With Severe Hemop
NCT02615691
Baxalta now part of ShirePhase 3
CompletedA Single Escalating Dose and Multiple Dose Study of BAY 1093884 in Subjects With Severe Hemophilia Types A or
NCT02571569
BayerPhase 1
CompletedAn Open-label Extension Study of an Investigational Drug, Fitusiran, in Patients With Moderate or Severe Hemop
NCT02554773
Genzyme, a Sanofi CompanyPhase 1 / Phase 2
CompletedNational Study of a Pharmacokinetic-Focused Educational Package for Patients With Severe Haemophilia A
NCT02528968
Hampshire Hospitals NHS Foundation TrustN/A
CompletedCharacterization of Laboratory Response to DDAVP in Adult Hemophilia A Carriers
NCT02506023
Emory UniversityPhase 1
TerminatedFc factOrs and Real-World hemophiliA Patient-ReporteD Outcomes
NCT02392156
Bioverativ Therapeutics Inc.
CompletedStudy of PF-05208756, Moroctocog Alfa (AF-CC), Xyntha For Male Chinese Subjects With Hemophilia A
NCT02461992
PfizerPhase 1
CompletedSingle Dose Study in Subjects With Severe Hemophilia A Comparing Pharmacokinetic Parameters for BAY81-8973 and
NCT02483208
BayerPhase 1
CompletedA Prospective Study to Collect High-Quality Documentation of Bleeds, Health-Related Quality of Life (HRQoL), a
NCT02476942
Hoffmann-La Roche
CompletedComparison of Different Prophylaxis Regimens for Moderate to Severe Hemophilia A Pediatric Patients
NCT02727647
Chulalongkorn UniversityPhase 4
CompletedA Study of a Long-Acting r-Factor 7a (Factor VIIa) in Adult Men With Hemophilia A or B
NCT02418793
OPKO Health, Inc.Phase 1
CompletedPF-05208756, Moroctocog Alfa (AF-CC), Xyntha For Hemophilia A
NCT02492984
PfizerPhase 4
CompletedPlatelet Function in Patients With Hemophilia A
NCT02093065
Boston Children's Hospital
CompletedColorado Adult Joint Assessment Scale (CAJAS) Validation
NCT02284789
BayerN/A
Completed2-cohort Study of Adult Patients With Severe Hemophilia A in Greece
NCT02319070
Bayer
CompletedAn Open Label Study to Determine the Safety and Efficacy of Replacement Factor VIII Protein (Known as rFVIIIFc
NCT02234323
Bioverativ, a Sanofi companyPhase 3
CompletedWeb-based Application for the Population Pharmacokinetic Service - Phase 1
NCT02061072
McMaster University
UnknownSafety/Efficacy Study to Assess Whether FVIII/VWF Concentrate Can Induce Immune Tolerance in Haemophilia A Pat
NCT02479087
Fondazione IRCCS Ca' Granda, Ospedale Maggiore PoliclinicoPhase 4
CompletedNon-interventional Post-authorisation Study to Document the Immunogenicity, Safety, and Efficacy of NUWIQ
NCT02962765
Octapharma
UnknownEvaluate Efficacy and Safety of ADVATE in the Standard Prophylaxis Treatment of Severe or Moderately Severe He
NCT02282410
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolN/A
TerminatedA Study Comparing Factor Level and Inhibitor Titer Testing Results Drawn From Central Venous Lines and Venipun
NCT02402829
Children's Mercy Hospital Kansas City
UnknownEfficacy and Safety of ADVATE Standard Prophylaxis to Hemophilia A
NCT02280265
Nanjing Medical UniversityN/A
CompletedBAX 855 Pediatric Study
NCT02210091
Baxalta now part of ShirePhase 3
CompletedAn Open-label Safety and Efficacy Study of Recombinant FVIII in Patients With Severe Hemophilia A
NCT02172950
CSL BehringPhase 3
CompletedRetrospective Study in Chinese Pediatric Hemophilia A Patients With rFⅧ Contained Regular Prophylaxis
NCT02263066
Bayer
CompletedPhenotypic Heterogeneity in Hemophilia A: An Investigation of the Role of Platelet Function
NCT02225483
CancerCare Manitoba
CompletedStudy of Prophylaxis, ACtivity and Effectiveness (SPACE) in Hemophilia Patients Currently Treated With ADVATE
NCT02190149
Baxalta now part of Shire
CompletedChina ADVATE PTP Study
NCT02170402
Baxalta now part of ShirePhase 4
CompletedIndividualizing Hemophilia Prophylaxis Using Thromboelastography
NCT02582060
Children's Hospital Los AngelesN/A
CompletedEvaluation of Clot Stability Induced by Solulin: Evaluation of New Solulin Mutants Lacking Protein C Activatio
NCT02911233
University Hospital, Caen
CompletedPost Marketing Surveillance To Observe Safety And Efficacy Of Xyntha® In Subjects With Hemophilia A
NCT01790828
Pfizer
CompletedEvaluation Of Acceptability And Satisfaction Of Hemophilia Patients Treated With FusENGO
NCT01959919
Pfizer
CompletedA Phase 1 Study of an Investigational Drug, ALN-AT3SC, in Healthy Volunteers and Hemophilia A or B Patients
NCT02035605
SanofiPhase 1
UnknownSafety and Efficacy Extension Study of GreenGene™ F in Previously Treated Patients Diagnosed With Severe Hemop
NCT02027779
Green Cross CorporationPhase 3
CompletedPhase 3 Efficacy and Safety Study of BAX 855 in Severe Hemophilia A Patients Undergoing Surgical Procedures
NCT01913405
Baxalta now part of ShirePhase 3
CompletedBAX 855 Continuation
NCT01945593
Baxalta now part of ShirePhase 3
CompletedADVATE 2 mL Post-Authorization Safety Surveillance (PASS)
NCT02093741
Baxalta now part of Shire
CompletedAn Institutional Pilot Study to Investigate Physical Activity Patterns in Boys With Hemophilia
NCT02199717
The Hospital for Sick Children
CompletedSafety and Efficacy of BAY94-9027 in Previously Treated Male Children With Haemophilia A
NCT01775618
BayerPhase 3
UnknownSafety, Efficacy and Pharmacokinetics of GreenGene™ F to Previously Treated Patients With Severe Hemophilia A
NCT01619046
Green Cross CorporationPhase 3
CompletedProphylaxis Versus on Demand Treatment for Children With Hemophilia A
NCT01810666
BayerPhase 4
CompletedStudy on Von Willebrand Disease and Hemophilia in Cuenca, Ecuador
NCT01589848
Universidad del Azuay
UnknownGlobal Hemostatic Methods in Hemophilia and Von Willebrand's Disease
NCT02061033
Karolinska University Hospital
CompletedRecombinant Factor VIIa BI (rFVIIa BI) Treatment of Acute Bleeding Episodes Per an On-demand Regimen
NCT01757405
Baxalta now part of ShirePhase 3
CompletedStudy Investigating a PEGylated Recombinant Factor VIII (BAX 855) for Hemophilia A (PROLONG-ATE Study)
NCT01736475
Baxalta now part of ShirePhase 2 / Phase 3
TerminatedStudy of Biostate for Treatment of Children With Hemophilia A Complicated by Antibody Development
NCT01445197
CSL BehringPhase 3
CompletedComparison of Prophylaxis and On-demand Treatment in Children With Moderate to Severe Hemophilia A
NCT02362581
Chulalongkorn UniversityN/A
CompletedStudy to Evaluate the Safety, Efficacy, and Pharmacokinetics of Recombinant Coagulation Factor VIII Fc Fusion
NCT01458106
Bioverativ Therapeutics Inc.Phase 3
CompletedViscosupplementation in Patients With Hemophilic Arthropathy
NCT01748201
University of Sao Paulo General HospitalPhase 4
CompletedRelative Bioavailability Of Two Formulations Of Moroctocog Alfa (AF-CC)
NCT01579903
PfizerPhase 1
CompletedComparative Pharmacokinetic Study of Two Different Strengths of BAY14-2222
NCT01653639
BayerPhase 1
UnknownPersonalized Prediction of Tolerance and Immunogenicity in Hemophilia
NCT01626105
Victor J Marder, M.D.
CompletedA Trial Investigating Safety and Efficacy of Treatment With BAY94-9027 in Severe Hemophilia A
NCT01580293
BayerPhase 2 / Phase 3
CompletedAn Open-label Safety, Efficacy and Pharmacokinetic Study of a Recombinant FVIII Compared to Recombinant Human
NCT01486927
CSL BehringPhase 2 / Phase 3
WithdrawnNon Neutralizing Antibodies: Prevalence and Characterization
NCT01541527
University Hospital, Montpellier
CompletedLong-Term Safety and Efficacy of rFVIIIFc in the Prevention and Treatment of Bleeding Episodes in Previously T
NCT01454739
Bioverativ Therapeutics Inc.Phase 3
CompletedPhase 1 Safety, Pharmacokinetics And Pharmacodynamics Study Of Recombinant Factor VIIa Variant (813d) In Adult
NCT01439971
Catalyst BiosciencesPhase 1
CompletedInhibitor Development in Patients With Hemophilia A Undergoing Surgery
NCT01571934
Emory University
CompletedInternet-based Educational Program to Promote Self-Management for Teens With Hemophilia
NCT01477437
The Hospital for Sick ChildrenN/A
TerminatedOsteoporosis and MRI Study in Hemophilia
NCT01460147
Baxalta now part of ShireN/A
TerminatedStudy of Modified Recombinant Factor VIII (OBI-1) in Subjects With Congenital Hemophilia A
NCT01434511
Baxalta now part of ShirePhase 3
CompletedBAX 855 Dose-Escalation Safety Study
NCT01599819
Baxalta now part of ShirePhase 1
TerminatedEarly Prophylaxis Immunologic Challenge (EPIC) Study
NCT01376700
Baxalta now part of ShirePhase 3
CompletedHemophilia Inhibitor Previously Untreated Patient Study
NCT01652027
The University of Texas Health Science Center, Houston
CompletedADVATE/ ADYNOVI Hemophilia A Outcome Database (AHEAD)
NCT02078427
Baxalta now part of Shire
CompletedKogenate FS Regulatory Post-Marketing Surveillance
NCT01386268
Bayer
CompletedSocialization of Adult Men With Congenital Hemophilia A or B
NCT01510418
Dana-Farber Cancer Institute
CompletedA Trial to Compare Prophylaxis Therapy to On-demand Therapy With a New Full Length Recombinant FVIII in Patien
NCT01233258
BayerPhase 3
CompletedBiomarkers Serum Collection Methodology Pilot Study
NCT01318707
Georgetown University
CompletedTrial to Evaluate the Pharmacokinetics and Safety Profile of BAY94-9027 Following Single and Multiple Dose Adm
NCT01184820
BayerPhase 1
CompletedComparing the Burden of Illness of Hemophilia in the Developing and the Developed World
NCT01217255
The Hospital for Sick Children
CompletedStudy of Biostate® in Children With Hemophilia A
NCT01229007
CSL BehringPhase 3
CompletedClinical Study to Investigate the Pharmacokinetics, Efficacy, Safety and Immunogenicity of a Recombinant FVIII
NCT00989196
OctapharmaPhase 2
CompletedCorrelation Between Vitamin D Status and Bone Mineral Density in Patients With Hemophilia
NCT01090206
Virginia Commonwealth UniversityN/A
CompletedStudy of Safety And Efficacy Of ReFacto AF In Previously Untreated Hemophilia A Patients In The Usual Care Set
NCT00950170
PfizerPhase 4
CompletedQuality of Life Study of Helixate NexGen
NCT01053715
CSL Behring
CompletedSurvey of Inhibitors in Plasma-Product Exposed Toddlers
NCT01064284
Fondazione Angelo Bianchi BonomiPhase 4
CompletedEfficacy and Safety of IL-11 in DDAVP Unresponsive
NCT00994929
University of PittsburghPhase 2
CompletedTrial to Evaluate the Efficacy and Safety of a New Full Length Recombinant Human FVIII for Hemophilia A
NCT01029340
BayerPhase 3
CompletedStudy Evaluating Safety And Efficacy Of Moroctocog Alfa (AF-CC) In Previously Treated Hemophilia A Patients
NCT00914459
PfizerPhase 4
TerminatedStudy of Ataluren (PTC124) in Hemophilia A and B
NCT00947193
PTC TherapeuticsPhase 2
CompletedHealth Related Quality of Life of Youth and Young Adults With Hemophilia A
NCT01034904
CSL Behring
CompletedEffekt-2 - Efficacy and Safety of Long-term Treatment With KOGENATE® FS in Latin America
NCT00969319
Bayer
TerminatedIndividually Tailored Prophylaxis in Patients With Severe Hemophilia A
NCT00995046
Hospices Civils de LyonN/A
CompletedStudy Evaluating Pharmacovigilance Of Refacto AF
NCT00895037
Pfizer
CompletedPharmacokinetic Study of ADVATE 3000 IU in Previously Treated Patients With Severe Hemophilia A
NCT00916032
Baxalta now part of ShirePhase 4
CompletedJoint Status in Subjects With Severe Hemophilia A in Relation to Different Treatment Regimens
NCT00927667
BayerPhase 4
TerminatedStudy Evaluating The Efficacy And Safety Of Xyntha In Children Less Than 6 Years Of Age
NCT00759655
Wyeth is now a wholly owned subsidiary of PfizerPhase 3
TerminatedStudy Evaluating Safety Of Patients Switching To ReFacto AF In Usual Care Settings
NCT00884390
PfizerPhase 4
UnknownEfficacy and Safety of MK-0518 in Treatment-Experienced HIV-1 Infected Adult Patients With Hemophilia
NCT00797381
Shanghai Public Health Clinical Center
CompletedEffeKt Taiwan- Efficacy and Safety of Long-term Treatment With KOGENATE® FS in Taiwan
NCT00932555
Bayer

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