Clinical Trials Directory

Trials / Sponsors / Shenzhen Geno-Immune Medical Institute

Shenzhen Geno-Immune Medical Institute

Academic / Other · 69 registered clinical trials34 currently recruiting.

StatusTrialPhaseStarted
RecruitingH3K27M-specific Immune Effector Cells Targeting DMG/DIPG
Diffuse Midline Glioma or Diffuse Intrinsic Pontine Glioma
Phase 1 / Phase 22026-03-18
RecruitingcfMSC Therapy for Diabetes
Type II Diabetes Mellitus
Phase 1 / Phase 22026-03-16
RecruitingcfMSC Stem Cell Therapy Targeting COPD
Chronic Obstructive Pulmonary Disease (COPD)
Phase 1 / Phase 22026-03-10
RecruitingDLL3 CAR-T Therapy Targeting Brain Tumors
Glioblastoma of Cerebellum
Phase 1 / Phase 22025-09-10
RecruitingNG2 and DLL3 CAR-T Cells Targeting Melanoma
Melanoma
Phase 1 / Phase 22025-09-01
RecruitingCombination Immunotherapy Targeting Melanoma
Melanoma
Phase 1 / Phase 22025-08-31
RecruitingIT and IV Lentiviral Gene Therapy for X-ALD
X-linked Adrenoleukodystrophy
N/A2025-08-31
RecruitingCombination CAR-T Cell Therapy Targeting Hematological Malignancies
B-cell Malignancies
Phase 1 / Phase 22025-08-01
RecruitingIntervention of Bladder Cancer by CAR-T
Bladder Cancer, Urothelial Carcinoma Bladder
Phase 1 / Phase 22025-08-01
RecruitingProstate Cancer Vaccines
Prostate Cancer Indications
Phase 1 / Phase 22025-06-15
RecruitingLentiviral Hematopoietic Stem Cell Gene Therapy for MLD
Metachromatic Leukodystrophy (MLD)
N/A2025-06-01
RecruitingDirect Lentiviral Injection Gene Therapy for MLD
Metachromatic Leukodystrophy (MLD)
N/A2025-05-31
RecruitingGenetically Modified T Cells Against Ovarian Cancer
Ovarian Cancer
Phase 1 / Phase 22025-05-01
RecruitingA Phase I/II Multiple Center Trial of 4SCAR19 Cells in the Treatment of Relapsed and Refractory B Cell Maligna
B-cell Malignancies
Phase 1 / Phase 22025-05-01
RecruitingStudy on GD2 Positive Solid Tumors by 4SCAR-GD2
Solid Tumor
Phase 1 / Phase 22025-05-01
Enrolling By InvitationClonal Fetal Mesenchymal Stem Cells (cfMSCs) for the Control of Immune-related Disorders
Immune Related Disorder, Tissue Damage
Phase 12025-01-01
RecruitingSCID-X1 Gene Therapy Via Intravenous Lentiviral (Ivlv-X1) Injection
SCID, X-Linked
Phase 1 / Phase 22024-06-30
RecruitingGene Therapy for ADA-SCID Using an Improved Lentiviral Vector (Ivlv-ADA)
Adenosine DeAminase Severe Combined ImmunoDeficiency (ADA-SCID)
N/A2024-06-30
RecruitingAutoimmune Disease Treatment With Mesenchymal Stem Cells (MSCs) and CAR-T Cells
Autoimmune Diseases
Phase 1 / Phase 22024-05-15
RecruitingFrontline Combination CAR-T Cell Therapy for Multiple Myeloma or Plasmacytoma
Multiple Myeloma, Plasmacytoma
Phase 1 / Phase 22024-05-11
RecruitingEngineered Dendritic Cell Vaccines for Multiple Myeloma
Multiple Myeloma or Plasmacytoma
Phase 12024-05-11
RecruitingUniversal 4SCAR7U Targeting CD7-positive Malignancies
T-cell Acute Lymphoblastic Leukemia, T-cell Acute Lymphoblastic Lymphoma, Acute Myeloid Leukemia
Phase 12023-10-31
Recruiting4SCAR19U T Cells Targeting B Cell Malignancies
B Cell Malignancies
Phase 12023-10-31
RecruitingUniversal CAR-T Cells Targeting Multiple Myeloma
Multiple Myeloma in Remission
Phase 12023-10-31
RecruitingUniversal CAR-T Cells Targeting AML
Acute Myeloid Leukemia
Phase 12023-10-31
RecruitingCAR-T Cells Targeting Autoimmune Diseases
Autoimmune Diseases
Phase 1 / Phase 22022-07-31
RecruitingCD19/70 Bi-specific CAR-T Cell Therapy
B Cell Malignancies
Phase 1 / Phase 22022-06-30
RecruitingGD2/PSMA Bi-specific CAR-T Cell Therapy
Solid Tumor
Phase 1 / Phase 22022-06-30
RecruitingCD19/79b Bi-specific CAR-T Cell Therapy
B Cell Malignancies
Phase 1 / Phase 22022-06-30
RecruitingCD19/22 Bi-specific CAR-T Cell Therapy
B Cell Malignancies
Phase 1 / Phase 22022-06-30
RecruitingPSMA/CD70 Bi-specific CAR-T Cell Therapy
Cancer Disease
Phase 1 / Phase 22022-06-30
RecruitingGD2/CD56 Bi-specific CAR-T Cell Therapy
Malignant Disease
Phase 1 / Phase 22022-06-30
RecruitingGD2/CD70 Bi-specific CAR-T Cell Therapy
Cancer Disease
Phase 1 / Phase 22022-06-30
UnknownNGS-MRD Assessment of Combination Immunotherapies Targeting T-ALL
T-Cell Acute Lymphoblastic Leukemia
Phase 12022-03-15
UnknownNGS-MRD Assessment of Combination Immunotherapies Targeting B-ALL
B-Cell Acute Lymphoblastic Leukemia
Phase 12022-03-01
Unknown4SCAR-T Therapy Targeting GD2, PSMA and CD276 for Treating Neuroblastoma
Neuroblastoma
Phase 1 / Phase 22020-11-18
UnknownCombination Immunotherapy Targeting Sarcomas
Sarcoma, Osteoid Sarcoma, Ewing Sarcoma
Phase 1 / Phase 22020-07-01
UnknownMulti-4SCAR-T Therapy Targeting Breast Cancer
Breast Cancer
Phase 1 / Phase 22020-06-01
Unknown4SCAR-CD44v6 T Cell Therapy Targeting Cancer
Cancers Which Are CD44v6 Positive
Phase 1 / Phase 22020-06-01
UnknownLentiviral FIX Gene Therapy
Hemophilia B
Phase 12020-06-01
UnknownLentiviral FVIII Gene Therapy
Hemophilia A
Phase 12020-06-01
Unknown4SCAR-T Therapy Post CD19-targeted Immunotherapy
CD19 Negative B-cell Malignancies
Phase 1 / Phase 22020-06-01
UnknownTargeting CD276 (B7-H3) Positive Solid Tumors by 4SCAR-276
Solid Tumor
Phase 1 / Phase 22020-06-01
UnknownMulti-CAR-T Cells Targeting B Cell Lymphomas
B Cell Lymphoma (BCL)
Phase 1 / Phase 22020-06-01
UnknownImmunity and Safety of Covid-19 Synthetic Minigene Vaccine
Pathogen Infection Covid-19 Infection
Phase 1 / Phase 22020-03-24
UnknownSafety and Immunity of Covid-19 aAPC Vaccine
Treat and Prevent Covid-19 Infection
Phase 12020-02-15
UnknownPSMA-specific CAR-T Cell Therapy
PSMA Positive Tumors or Tumor Tissues
Phase 1 / Phase 22020-01-01
UnknownImmunotherapy Based on Antigen-specific Immune Effector Cells Targeting Neurofibromatosis or Schwannomatosis
Cancer
Phase 1 / Phase 22019-09-01
UnknownMulti-CAR T Cell Therapy Targeting CD7-positive Malignancies
T-cell Acute Lymphoblastic Leukemia, T-cell Acute Lymphoblastic Lymphoma, Acute Myeloid Leukemia
Phase 1 / Phase 22019-09-01
UnknownMultiple CAR-T Cell Therapy Targeting AML
Acute Myeloid Leukemia
Phase 1 / Phase 22019-08-01
UnknownCAR-T Immunotherapy Targeting CD19- ALL
B-cell Leukemia
Phase 1 / Phase 22019-07-15
UnknownImmune Modulatory DC Vaccine Against Brain Tumor
Diffuse Intrinsic Pontine Glioma or Glioblastoma
Phase 12019-03-31
UnknownImmunotherapy Treating GI Cancer
Cancer
Phase 1 / Phase 22018-07-01
UnknownLentiviral Gene Therapy for CGD
Chronic Granulomatous Disease
N/A2018-07-01
UnknownImmunotherapy Based on Tumor Associated Antigen-specific Immune Effector Cells
Cancer
Phase 1 / Phase 22018-07-01
UnknownAntigen-specific T Cells Against Lung Cancer
Lung Cancer
Phase 1 / Phase 22017-12-15
UnknownFANCA Gene Transfer for Fanconi Anemia Using a High-safety, High-efficiency, Self-inactivating Lentiviral Vect
Fanconi Anemia
N/A2017-12-01
UnknownSafety and Efficacy Evaluation of 4th Generation Safety-engineered CAR T Cells Targeting Sarcomas
Sarcoma, Osteoid Sarcoma, Ewing Sarcoma
Phase 1 / Phase 22017-12-01
UnknownGene Therapy of Beta Thalassemia Using a Self-inactivating Lentiviral Vector
Beta-Thalassemia
N/A2017-12-01
SuspendedIntervention of Ovarian Cancer With Antigen-specific Engineered Immune Effectors
Ovarian Cancer
Phase 1 / Phase 22017-12-01
UnknownEngineered Immune Effectors Against Cervical Cancer
Cervical Cancer
Phase 1 / Phase 22017-11-15
UnknownIntervention of CAR-T Against Cervical Cancer
Cervical Cancer
Phase 1 / Phase 22017-11-15
WithdrawnIntervention of Engineered Immune Effector T Cells Against Lung Cancer
Lung Cancer, NSCLC
Phase 1 / Phase 22017-11-15
UnknownHPV Specific Immune Lymphocytes (HPV-CTLs) in the Treatment of HPV
Human Papilloma Virus
Phase 1 / Phase 22017-11-15
UnknownEngineered Immune Effectors Against Ovarian Cancer
Ovarian Cancer
Phase 1 / Phase 22017-11-15
UnknownAntigen-specific Cytotoxic T Cells in the Treatment of Opportunistic Infections
Pathogen Infection, EBV Infection, CMV Infection
Phase 1 / Phase 22017-07-15
UnknownMulti-CAR T Cell Therapy in the Treatment of Multiple Myeloma
Multiple Myeloma
Phase 1 / Phase 22017-07-15
UnknownMulti-CAR T Cell Therapy for Acute Myeloid Leukemia
Acute Myeloid Leukemia
Phase 1 / Phase 22017-07-15
Enrolling By InvitationImmunogene-modified T (IgT) Cells Against Glioblastoma Multiforme
Glioblastoma Multiforme of Brain, Brain Cancer
Phase 12017-05-31