Clinical Trials Directory

Trials / Sponsors / Genentech, Inc.

Genentech, Inc.

Industry · 505 registered clinical trials25 currently recruiting.

StatusTrialPhaseStarted
RecruitingA Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Pharmacodynamics, and Efficacy of P-CD19CD20-
Systemic Lupus Erythematosus
Phase 12026-06-30
RecruitingA Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Re
Atherosclerosis
Phase 22026-04-30
RecruitingA Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participa
Diabetic Macular Edema
Phase 12026-04-22
RecruitingA Dose-Escalation Study of RO7875913 in Healthy Participants
Healthy Volunteers
Phase 12026-03-11
RecruitingA Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-0587 as a Monotherapy and in Combination
Breast Cancer
Phase 12026-01-13
RecruitingA Study to Evaluate the Effect of Food and Proton Pump Inhibitor on the Pharmacokinetics of ZN-A-1041 in Healt
Healthy Volunteers
Phase 12025-11-21
RecruitingA Study to Assess the Bioequivalence of Trastuzumab Via Different Subcutaneous Delivery Platforms in Healthy M
Healthy Participants
Phase 12025-10-17
RecruitingA Study to Evaluate the Safety, Tolerability, Cellular Kinetics, and Pharmacodynamics of P-CD19CD20-ALLO1 in P
Multiple Sclerosis
Phase 12025-10-15
RecruitingA Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and G
Breast Cancer
Phase 1 / Phase 22025-10-07
RecruitingA Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderate
Ulcerative Colitis
Phase 22025-09-29
RecruitingA Study to Evaluate the Effect of Moderate or Severe Hepatic Impairment on the Pharmacokinetics (PK) of Inavol
Hepatic Impairment
Phase 12025-08-21
CompletedA Study to Evaluate the Relative Bioavailability of Two Tablet Formulations Compared to Capsule Formulation an
Healthy Participants
Phase 12025-06-27
CompletedA Study to Assess the Tolerability and Safety of Subcutaneously (SC) Administered Immunoglobulin G (IgG) With
Healthy Participants
Phase 12025-06-02
RecruitingA Study to Evaluate the Activity, and Safety of Vixarelimab in Participants With Moderate to Severe Active Ulc
Moderate to Severe Ulcerative Colitis
Phase 1 / Phase 22025-03-31
CompletedA Study to Evaluate the Effect of Rifampin on the Pharmacokinetics of Divarasib in Healthy Participants
Healthy Participants
Phase 12025-02-21
CompletedA Study to Evaluate the Pharmacokinetics of Divarasib in Healthy Participants and Participants With Impaired H
Hepatic Impairment
Phase 12025-01-31
TerminatedA Study to Evaluate the Efficacy and Safety of GDC-8264 in Preventing Cardiac Surgery-Associated Acute Kidney
Acute Kidney Injury
Phase 22025-01-17
TerminatedA Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7759065 as a Single Agent and in Combinati
Solid Tumour
Phase 12024-12-16
RecruitingA Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease
Non-cystic Fibrosis Bronchiectasis, Chronic Obstructive Pulmonary Disease
Phase 1 / Phase 22024-11-18
CompletedA Study to Determine the Effect of Itraconazole on the Pharmacokinetics of Divarasib in Healthy Participants
Healthy Participants
Phase 12024-11-15
RecruitingA Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in
Solid Tumor
Phase 12024-11-14
CompletedA Clinical Trial to Investigate the Clinical Drug-Drug Interaction of Divarasib With Probe Substrates of P-Gly
Healthy Participants
Phase 12024-11-06
WithdrawnA Study of RO7617991 in Patients With Locally Advanced or Metastatic MAGE-A4-Positive Solid Tumors
Refractory Cancer, Recurrent Cancer, Solid Tumor, Adult
Phase 12024-09-30
Active Not RecruitingA Study to Evaluate the Effect of Venetoclax on Participants Receiving a Covalent Bruton's Tyrosine Kinase Inh
Chronic Lymphocytic Leukemia
Phase 22024-08-09
RecruitingA Study Evaluating Atezolizumab, With or Without Bevacizumab, in Participants With Unresectable Hepatocellular
Hepatocellular Carcinoma
Phase 22024-07-15
CompletedA Study to Evaluate the Effect of Injection Site on PK of Astegolimab in Healthy Subjects
Healthy Volunteers
Phase 12024-06-17
TerminatedA Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Vixarelimab in Participants With Moderate to
Ulcerative Colitis
Phase 22024-05-01
CompletedStudy to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Either Osimertini
Colorectal Cancer, Non-Small Cell Lung Cancer
Phase 12024-01-08
RecruitingA Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7566802 as a Single Agent and in Combinati
Locally Advanced Solid Tumors, Recurrent Solid Tumors, Metastatic Solid Tumors
Phase 12023-11-27
RecruitingA Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFO
Adenocarcinoma, Pancreatic Ductal
Phase 22023-10-18
Active Not RecruitingA Study to Evaluate Safety, Pharmacokinetics, & Activity of RO7496353 in Combination With a Checkpoint Inhibit
Non-small Cell Lung Cancer, Gastric Cancer, Pancreatic Ductal Adenocarcinoma
Phase 12023-10-02
RecruitingA Study Evaluating the Safety, Pharmacokinetics, and Activity of the Combination of Cevostamab and Elranatamab
Relapsed or Refractory Multiple Myeloma
Phase 12023-08-10
TerminatedA Study Evaluating the Efficacy and Safety of Vixarelimab in Participants With Idiopathic Pulmonary Fibrosis a
Idiopathic Pulmonary Fibrosis, Systemic Sclerosis With Lung Involvement
Phase 22023-05-26
RecruitingA Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Me
Advanced Prostate Cancer, Metastatic Prostate Cancer
Phase 12023-05-02
CompletedA Study to Assess the Safety and Pharmacokinetics of GDC-8264 in Combination With Standard of Care in Particip
Acute Graft-versus-host Disease
Phase 12023-04-06
RecruitingA Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participant
Geographic Atrophy
Phase 22023-03-23
CompletedA Study To Evaluate The Efficacy, Safety, Pharmacokinetics, And Pharmacodynamic Effects Of GDC-6599 In Patient
Chronic Refractory Cough (CRC) With Non-atopic Asthma, CRC With Atopic Asthma, Unexplained Chronic Cough
Phase 22023-03-22
Active Not RecruitingA Study to Evaluate the Safety, Pharmacokinetics, and Activity of XmAb24306 in Combination With Cevostamab in
Multiple Myeloma
Phase 12023-03-21
CompletedA Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of RO7303509 in Participants With Systemic
Systemic Sclerosis
Phase 12023-01-16
Active Not RecruitingA Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7497372
Diabetic Macular Edema
Phase 12022-12-08
CompletedA Study to Characterize Access to Specialty Care Received by American Indians/Alaska Natives
Specialist Referral: Neurology, Specialist Referral: Ophthalmology, Specialist Referral: Oncology
2022-12-02
RecruitingA Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combinat
Locally Advanced or Metastatic Solid Tumors, NSCLC, HNSCC
Phase 12022-10-20
CompletedA Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Atezolizumab in
Advanced Solid Tumors, Metastatic Solid Tumors
Phase 12022-08-17
Active Not RecruitingA Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With the Physician's Choic
Estrogen Receptor (ER)-Positive, HER2-negative, Locally Advanced or Metastatic Breast Cancer
Phase 32022-08-03
WithdrawnA Study of MTPS9579A in Participants With Refractory Chronic Spontaneous Urticaria
Chronic Spontaneous Urticaria
Phase 22022-07-31
RecruitingA Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of RO7446603 Administered Alone o
Diabetic Macular Edema
Phase 1 / Phase 22022-06-22
Active Not RecruitingAn Observational Study of the Progression of Intermediate Age-Related Macular Degeneration
Age-Related Macular Degeneration
2022-05-27
CompletedA Study to Evaluate the Safety and Pharmacokinetics of XMAB24306 in Combination With Daratumumab in Participan
Multiple Myeloma
Phase 12022-04-28
Active Not RecruitingLong-term Follow-up Study of Risdiplam in Participants With Spinal Muscular Atrophy (SMA)
Spinal Muscular Atrophy
Phase 42022-03-29
Active Not RecruitingA Study to Investigate Faricimab Treatment Response in Treatment-Naive, Underrepresented Patients With Diabeti
Diabetic Macular Edema
Phase 42022-02-28
Active Not RecruitingA Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab Monotherapy in Participants Wit
Non-Hodgkin Lymphoma
Phase 22022-02-01
RecruitingA Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration
Neovascular Age-related Macular Degeneration
Phase 42021-12-14
TerminatedA Study Of ¹²⁹XE MRI To Assess Disease Progression In Patients With COPD Treated With Or Without Azithromycin
Chronic Obstructive Pulmonary Disease
Phase 22021-11-16
CompletedA Study to Evaluate the Efficacy and Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary
Chronic Obstructive Pulmonary Disease
Phase 22021-10-05
Active Not RecruitingA Study Evaluating the Safety, Pharmacokinetics, and Activity of Cevostamab in Participants With Relapsed or R
Multiple Myeloma
Phase 12021-07-26
Active Not RecruitingA Study to Evaluate the Safety and Activity of Belvarafenib as a Single Agent and in Combination With Either C
Melanoma
Phase 12021-05-13
CompletedA Study Evaluating Targeted Therapies in Participants Who Have Advanced Solid Tumors With Genomic Alterations
Advanced Unresectable or Metastatic Solid Malignancy
Phase 22021-01-13
CompletedStudy to Investigate the Absorption, Metabolism, and Excretion of [14C]-GDC-9545 Following a Single Oral Dose
Healthy Volunteers
Phase 12021-01-07
TerminatedA Study to Assess the Impact of Omalizumab on Exercise Capacity, Physical Activity, and Sleep Quality in Parti
Moderate-to-severe Allergic Asthma
Phase 42020-11-30
CompletedStudy to Evaluate the Safety and Pharmacokinetics of Efmarodocokin Alfa in Combination With Standard of Care i
Acute Graft-versus-host Disease
Phase 12020-11-19
TerminatedA Study Assessing the Long-Term Safety and Tolerability of Galegenimab (FHTR2163) in Participants With Geograp
Macular Degeneration, Age-Related, Geographic Atrophy
Phase 22020-11-16
RecruitingA Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell
Non-small Cell Lung Cancer
Phase 22020-11-06
CompletedEvaluation Comparing Tau PET Radiotracers, [18F]GTP1 and [18F]PI-2620 or [18F]MK-6240 in Subjects With Normal
Alzheimer Disease (AD)
Phase 12020-10-26
TerminatedA Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participa
Non-alcoholic Steatohepatitis
Phase 22020-09-30
CompletedA Study of BLYG8824A in Participants With Locally Advanced or Metastatic Colorectal Cancer
Colorectal Cancer
Phase 12020-08-31
CompletedA Study of the Biodistribution and Safety of [18F]GTP1 in Healthy Japanese Participants
Alzheimer Disease
Phase 12020-08-11
CompletedProspective Study to Assess Disease Activity and Biomarkers in Minority Participants With Relapsing Multiple S
Multiple Sclerosis, Relapsing
Phase 42020-07-30
Active Not RecruitingA Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Particip
Non-Small Cell Lung Cancer, Colorectal Cancer, Advanced Solid Tumors
Phase 12020-07-29
CompletedA Study Evaluating The Safety And Pharmacokinetics Of Escalating Doses Of RO7297089 In Patients With Relapsed
Refractory Multiple Myeloma, Relapsed Multiple Myeloma
Phase 12020-07-08
CompletedA Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe CO
COVID-19 Pneumonia
Phase 22020-06-02
CompletedA Study to Evaluate the Efficacy and Safety of Tocilizumab in Hospitalized Participants With COVID-19 Pneumoni
COVID-19 Pneumonia
Phase 32020-05-14
Active Not RecruitingAn Open-Label Dose-Escalation Study to Evaluate XmAb24306 as a Single Agent and in Combination With Atezolizum
Solid Tumors
Phase 12020-03-09
CompletedEvaluation of the Relative Bioavailability and Food Effect of GDC-9545 in Healthy Females of Non-Childbearing
Healthy Volunteers
Phase 12020-03-06
CompletedProspective Clinicogenomic Program
Non-Small Cell Lung Cancer (NSCLC), Small-Cell Lung Cancer (SCLC)
Phase 42019-12-13
CompletedA Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of MTPS9579A in Patients With Asthma Requiring
Asthma
Phase 22019-10-31
CompletedA Study of Giredestrant (GDC-9545) in Postmenopausal Women With Stage I-III Operable, Estrogen Receptor-Positi
Breast Cancer
Phase 12019-07-26
TerminatedA Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Preliminary Ac
Multiple Myeloma, Non-Hodgkin Lymphoma, B-Cell Lymphoma
Phase 12019-07-22
CompletedA Performance and Bioavailability Study of Entrectinib in Healthy Volunteers.
Solid Tumor
Phase 12019-06-06
TerminatedA Study Assessing the Safety, Tolerability, and Efficacy of Galegenimab (FHTR2163) in Participants With Geogra
Macular Degeneration, Age-Related, Geographic Atrophy
Phase 22019-06-03
CompletedA Study to Assess the Efficacy, Safety, and Tolerability of KPL-716 in Reducing Pruritus in Chronic Pruritic D
Chronic Idiopathic Urticaria, Chronic Idiopathic Pruritus, Lichen Planus
Phase 22019-05-29
CompletedStudy to Assess the Efficacy, Safety, and Tolerability of Vixarelimab in Reducing Pruritus in Prurigo Nodulari
Prurigo Nodularis, Pruritis
Phase 22019-03-11
CompletedTenecteplase in Stroke Patients Between 4.5 and 24 Hours
THROMBOLYSIS
Phase 32019-03-02
CompletedA Study to Assess the Efficacy and Safety of MSTT1041A in Participants With Moderate to Severe Atopic Dermatit
Atopic Dermatitis
Phase 22019-02-06
CompletedA Study to Determine the Bioavailability of Various Formulations of GDC-0134 in Healthy Female Participants of
Healthy Volunteers
Phase 12019-02-01
CompletedA Study of Semorinemab in Patients With Moderate Alzheimer's Disease
Alzheimer's Disease
Phase 22019-01-25
TerminatedAn Extension Study to Evaluate the Long-Term Safety and Tolerability of UTTR1147A in Participants With Moderat
Ulcerative Colitis, Crohn's Disease
Phase 22019-01-14
CompletedA Study to Investigate the Bioequivalence of Two Different Forms of Entrectinib (Forms A and C) Under Fasted C
Healthy Volunteers
Phase 12019-01-10
CompletedA Study to Investigate the Relative Bioavailability of Entrectinib Capsule Formulations F1 and F06 Under Fed C
Healthy Volunteers
Phase 12019-01-09
CompletedA Study to Evaluate the Efficacy and Safety of Autogene Cevumeran (RO7198457) in Combination With Pembrolizuma
Advanced Melanoma
Phase 22018-12-21
CompletedA Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of UTTR1147A Compared With Placebo and With Ved
Ulcerative Colitis
Phase 22018-10-26
TerminatedA Study to Evaluate the Long-term Safety and Efficacy of Fenebrutinib in Participants Previously Enrolled in a
Urticaria
Phase 22018-09-27
CompletedA Study to Evaluate the Safety of Administering Ocrelizumab Per a Shorter Infusion Protocol in Participants Wi
Multiple Sclerosis
Phase 32018-09-14
CompletedA Study of Tiragolumab in Combination With Atezolizumab in Chemotherapy-Naïve Patients With Locally Advanced o
Non-small Cell Lung Cancer
Phase 22018-08-10
TerminatedStudy of Emicizumab Prophylaxis in Participants With Hemophilia A With or Without Inhibitors Undergoing Minor
Hemophilia A
Phase 42018-06-28
Active Not RecruitingA Study of Runimotamab in Participants With Locally Advanced or Metastatic HER2-Expressing Cancers
Solid Tumors
Phase 12018-06-06
CompletedSafety, Tolerability, and Pharmacokinetic (PK) Study of DHES0815A in Participants With Human Epidermal Growth
Breast Cancer
Phase 12018-04-17
TerminatedAn Extension Study of GDC-0853 in Participants With Moderate to Severe Active Systemic Lupus Erythematosus
Lupus Erythematosus, Systemic
Phase 22018-01-09
CompletedA Study of Autogene Cevumeran (RO7198457) as a Single Agent and in Combination With Atezolizumab in Participan
Melanoma, Non-Small Cell Lung Cancer, Bladder Cancer
Phase 12017-12-21
TerminatedA Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Effects of Single and Multiple Ascen
Healthy Volunteers
Phase 12017-12-08
Active Not RecruitingA Study of GDC-9545 Alone or in Combination With Palbociclib and/or Luteinizing Hormone-Releasing Hormone (LHR
Breast Cancer
Phase 12017-11-24
CompletedA Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in
Leukemia, Myeloid, Acute
Phase 12017-11-15
CompletedA Study of Ipatasertib in Participants With Mild, Moderate or Severe Hepatic Impairment Compared to Healthy Pa
Hepatic Insufficiency
Phase 12017-11-09
TerminatedA Study to Evaluate the Efficacy and Safety of Semorinemab in Patients With Prodromal to Mild Alzheimer's Dise
Alzheimer's Disease
Phase 22017-10-04
CompletedSafety and Tolerability Study of RO7171009 in Participants With Geographic Atrophy (GA) Secondary to Age-Relat
Geographic Atrophy
Phase 12017-09-21
CompletedDose-Escalation Study of Cevostamab in Participants With Relapsed or Refractory Multiple Myeloma (R/R MM)
Multiple Myeloma
Phase 12017-09-19
CompletedBioavailability of GDC-0134 and the Effect of Food and Proton Pump Inhibitor on Pharmacokinetics of GDC-0134 i
Amyotrophic Lateral Sclerosis
Phase 12017-08-07
CompletedStudy to Investigate the Safety, Tolerability, and Pharmacokinetics of DSTA4637S in Participants With Staphylo
Bacteremia
Phase 12017-07-13
CompletedA Study of GDC-0853 in Participants With Refractory Chronic Spontaneous Urticaria (CSU).
Urticaria
Phase 22017-05-26
TerminatedA Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated
Urothelial Carcinoma
Phase 22017-04-27
CompletedA Study of Atezolizumab as Neoadjuvant and Adjuvant Therapy in Resectable Non-Small Cell Lung Cancer (NSCLC) -
Non-Small Cell Lung Cancer
Phase 22017-04-20
CompletedA Study to Investigate the Effect of Formulation, Food, and Rabeprazole on the Pharmacokinetics (PK) of GDC-08
Healthy Volunteers
Phase 12017-04-18
CompletedA Drug-Drug Interaction Study Between GDC-0853 and Midazolam, Itraconazole, Rosuvastatin, and Simvastatin
Healthy Participants
Phase 12017-04-18
CompletedA Multiple Ascending Dose Study to Evaluate Safety and Tolerability of BFKB8488A in Participants With Type 2 D
Diabetes Mellitus, Type 2, Non-Alcoholic Fatty Liver Disease
Phase 12017-03-05
CompletedA Study of the Safety and Efficacy of GDC-0853 in Participants With Moderate to Severe Active Systemic Lupus E
Systemic Lupus Erythematosus
Phase 22017-01-19
Active Not RecruitingTo Evaluate the Safety, Tolerability, and Pharmacokinetics of Inavolisib Single Agent in Participants With Sol
Breast Cancer, Solid Tumor
Phase 12016-12-13
CompletedA Study to Compare Pharmacokinetics (PK) of Etrolizumab Administered Subcutaneously by a Prefilled Syringe Wit
Healthy Volunteers
Phase 12016-12-07
CompletedA Study to Evaluate the Long-Term Safety and Efficacy of GDC-0853 in Participants With Moderate to Severe Rheu
Rheumatoid Arthritis
Phase 22016-11-30
CompletedThe Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of UTTR1147A in Participants With Neuropathic
Neuropathic Diabetic Foot Ulcers
Phase 12016-11-14
CompletedA Study of MHAA4549A as Monotherapy for Acute Uncomplicated Seasonal Influenza A in Otherwise Healthy Adults
Influenza A
Phase 22016-10-12
CompletedA Study of Atezolizumab as First-line Monotherapy for Advanced or Metastatic Non-Small Cell Lung Cancer
Non-Small Cell Lung Cancer
Phase 22016-09-23
CompletedSafety and Efficacy Study of GDC-0853 Compared With Placebo and Adalimumab in Participants With Rheumatoid Art
Rheumatoid Arthritis
Phase 22016-09-09
CompletedA Study of RO7105705 in Healthy Participants and Participants With Mild-to-Moderate Alzheimer's Disease
Alzheimer's Disease
Phase 12016-06-29
WithdrawnA Study to Assess the Relative Bioavailability And Food Effect of a Tablet Formulation of GDC-0276 in Healthy
Healthy Volunteer
Phase 12016-06-01
CompletedA Study of GDC-0134 to Determine Initial Safety, Tolerability, and Pharmacokinetic Parameters in Participants
Amyotrophic Lateral Sclerosis
Phase 12016-05-31
CompletedA Study to Investigate the Effect of Itraconazole and Rifampin on Pharmacokinetics (PK) of Vemurafenib at Stea
Metastatic Melanoma, BRAF V600 Mutation Positive
Phase 12016-05-26
CompletedSafety and Pharmacokinetics (PK) of Escalating Doses of Tiragolumab as a Single Agent and in Combination With
Advanced/Metastatic Tumors
Phase 12016-05-23
CompletedA Pharmacokinetic Study of [14C]-GDC-0810 After Single Oral Administration in Healthy Female Participants
Healthy Volunteers
Phase 12016-05-01
CompletedStudy to Explore the Mechanism of Action of Ocrelizumab and B-Cell Biology in Participants With Relapsing Mult
Relapsing Multiple Sclerorsis, Multiple Sclerosis, Primary Progressive
Phase 32016-04-29
CompletedA Safety Study of Intravenously Administered UTTR1147A in Healthy Volunteers (HVs), Participants With Ulcerati
Ulcerative Colitis, Crohn's Disease
Phase 12016-04-11
CompletedA Study to Investigate the Safety, Pharmacokinetics, and Immunogenicity of BITS7201A in Healthy Volunteers and
Mild Atopic Asthma
Phase 12016-04-07
CompletedA Study in Patients With Neovascular Age Related Macular Degeneration or Macular Edema Secondary To Retinal Ve
Macular Edema
Phase 32016-03-21
CompletedA Study of Ocrelizumab in Participants With Relapsing Remitting Multiple Sclerosis (RRMS) Who Have Had a Subop
Multiple Sclerosis, Relapsing-Remitting
Phase 32016-02-11
CompletedStudy to Investigate the Effect of Formulation and Food on the Pharmacokinetics of GDC-0810
Healthy Volunteer
Phase 12016-01-06
CompletedLongitudinal Evaluation of [18F]GTP1 as a PET Radioligand for Imaging Tau in the Brain of Participants With Al
Alzheimer's Disease
Phase 12015-12-23
CompletedA Study of Pertuzumab With High-Dose Trastuzumab for the Treatment of Human Epidermal Growth Factor Receptor 2
Metastatic Breast Cancer
Phase 22015-12-16
TerminatedA Study of GDC-0810 Versus Fulvestrant in Postmenopausal Women With Advanced or Metastatic Breast Cancer Resis
Breast Cancer
Phase 22015-12-04
CompletedEffect of GDC-0810 on the Pharmacokinetics of Pravastatin in Healthy Female Subjects of Non-Childbearing Poten
Breast Cancer
Phase 12015-12-01
CompletedA Study to Evaluate Pain, Tolerability, Safety, and Usability of a Single Self-administered Etrolizumab by Aut
Healthy Volunteer
Phase 12015-12-01
CompletedA Study to Investigate Safety, Tolerability, and Pharmacokinetics of DSTA4637S in Healthy Volunteers
Healthy Volunteer
Phase 12015-11-29
Approved For MarketingAn Expanded Access Study of Atezolizumab in Participants With Locally Advanced or Metastatic Urothelial Carcin
Urothelial Carcinoma
2015-11-01
CompletedStudy to Evaluate Safety, Tolerability, and Pharmacokinetics of BFKB8488A in Otherwise Healthy Overweight and
Insulin Resistance
Phase 12015-10-29
CompletedIpatasertib (GDC-0068) Study to Evaluate Formulation Change and Food Effect on Bioavailability in Healthy Subj
Cancer
Phase 12015-10-01
CompletedStudy of the Efficacy and Safety of the Ranibizumab Port Delivery System for Sustained Delivery of Ranibizumab
Macular Degeneration
Phase 22015-09-28
CompletedA Safety, Efficacy and Pharmacokinetic Study of BTCT4465A (Mosunetuzumab) as a Single Agent and Combined With
Lymphocytic Leukemia, Chronic, Lymphoma, Non Hodgkin
Phase 1 / Phase 22015-09-15
CompletedA Study to Determine the Safety, Tolerability, and Pharmacokinetics of GDC-0310 in Healthy Volunteers
Healthy Volunteer
Phase 12015-09-15
CompletedEffect of Food, Rabeprazole, Methotrexate and Formulation on the Pharmacokinetics (PK) of GDC-0853 and the Eff
Healthy Volunteer
Phase 12015-09-03
CompletedA Study to Investigate the Safety, Tolerability, and Pharmacokinetics of MHAB5553A in Healthy Volunteers
Healthy Volunteer
Phase 12015-08-18
CompletedA Study of GDC-0919 and Atezolizumab Combination Treatment in Participants With Locally Advanced or Metastatic
Solid Tumor
Phase 12015-07-28
CompletedA Bioequivalence Study of Subcutaneous (SC) Lebrikizumab Administered by Needle and Syringe or by Prefilled Sy
Healthy Volunteer
Phase 12015-07-01
CompletedA Study of the Safety, Tolerability, and Effects of Cobimetinib and GDC-0994 in Patients With Locally Advanced
Non-Small Cell Lung Cancer, Metastatic Colorectal Cancer, Metastatic Non Small Cell Lung Cancer, Metastatic Cancers, Melanoma
Phase 12015-06-16
CompletedA Safety, Tolerability, and Pharmacokinetic Study of GDC-3280 in Healthy Participants
Healthy Volunteer
Phase 12015-06-01
CompletedA Study of the Efficacy and Safety of Omalizumab Through 48 Weeks in Participants With Chronic Idiopathic Urti
Urticaria
Phase 42015-05-18
CompletedA Study to Assess the Safety and Pharmacokinetics of MOXR0916 and Atezolizumab (Also Known as MPDL3280A or Ant
Neoplasms
Phase 12015-04-24
CompletedA Study in Healthy Volunteers to Assess the Relative Bioavailability and Tolerability of Two Crenezumab Formul
Healthy Volunteer
Phase 12015-04-01
CompletedA Study of Obinutuzumab + Bendamustine (BG) in Participants With Previously Untreated Chronic Lymphocytic Leuk
Chronic Lymphocytic Leukemia
Phase 22015-03-31
CompletedA Post-Marketing Study of the Immunogenicity of Somatropin (Ribosomal Deoxyribo Nucleic Acid [rDNA] Origin) In
Growth Hormone Deficiency
Phase 42015-03-31
CompletedA Study of Lampalizumab Intravitreal Injections Administered Every Two Weeks or Every Four Weeks to Participan
Geographic Atrophy
Phase 22015-03-30
CompletedA Study of GDC-0927 in Postmenopausal Women With Locally Advanced or Metastatic Estrogen Receptor Positive Bre
Breast Cancer
Phase 12015-03-17
CompletedA Phase I Bioavailability and Pharmacokinetic Study of [14C]-Ipatasertib Single Oral and Intravenous Doses in
Healthy Volunteer
Phase 12015-03-01
CompletedA Study of Crenezumab in Participants With Mild to Moderate Alzheimer Disease
Alzheimer Disease
Phase 12015-02-26
CompletedA Study of Ipatasertib (GDC-0068) in Combination With Paclitaxel as Neoadjuvant Treatment for Participants Wit
Breast Cancer
Phase 22015-02-17
CompletedA Study of MHAA4549A in Combination With Oseltamivir Versus Oseltamivir in Participants With Severe Influenza
Influenza
Phase 22015-01-14
TerminatedA Study of GDC-0810 Single Agent or in Combination With Palbociclib and/or a Luteinizing Hormone-Releasing Hor
Breast Cancer
Phase 1 / Phase 22014-12-29
CompletedA Study of Neoadjuvant Letrozole + Taselisib Versus Letrozole + Placebo in Post-Menopausal Women With Breast C
Breast Cancer
Phase 22014-11-12
CompletedA Study of High Dose MHAA4549A in Healthy Volunteers
Healthy Volunteer
Phase 12014-11-03
CompletedA Study Assessing the Safety and Efficacy of Adding Ipatasertib to Paclitaxel Treatment in Participants With B
Breast Neoplasms
Phase 22014-08-19
CompletedA Study to Assess Safety and Pharmacokinetics of MOXR0916 in Participants With Locally Advanced or Metastatic
Neoplasms
Phase 12014-08-12
CompletedA Study to Evaluate the Pharmacokinetics and Safety of Cobimetinib in Volunteers With and Without Liver Damage
Healthy Volunteer
Phase 12014-08-01
CompletedA Study Evaluating the Safety and Pharmacokinetics of DMUC4064A in Participants With Platinum-Resistant Ovaria
Pancreatic Neoplasms, Ovarian Neoplasms
Phase 12014-06-22
TerminatedA Study of the Efficacy and Safety of Alteplase in Participants With Mild Stroke
Stroke
Phase 32014-05-31
CompletedMy Pathway: A Study Evaluating Herceptin/Perjeta, Tarceva, Zelboraf/Cotellic, Erivedge, Alecensa, and Tecentri
Neoplasms, Solid Tumors, Biliary Cancer
Phase 22014-04-14
CompletedA Study of the Effect of Formulation and Tablet Hardness on the Bioavailability of Pictilisib in Healthy Volun
Healthy Volunteer
Phase 12014-04-01
CompletedA Randomized, Phase I, Cross-Over Study to Assess the Relative Bioavailability of Single-Dose Cobimetinib (GDC
Healthy Volunteer
Phase 12014-04-01
CompletedIndoleamine 2,3-Dioxygenase (IDO) Inhibitor in Advanced Solid Tumors
Solid Tumor
Phase 12014-04-01
CompletedA Study Evaluating the Safety of Escalating Doses of DLYE5953A in Patients With Refractory Solid Tumors
Neoplasms
Phase 12014-04-01
TerminatedA Study of DNIB0600A in Comparison With Pegylated Liposomal Doxorubicin (PLD) in Participants With Platinum-Re
Ovarian Cancer
Phase 22014-02-06
CompletedA Study Evaluating the Effect of Formulation on the Bioavailability of Ipatasertib in Healthy Volunteers
Healthy Volunteer
Phase 12014-02-01
CompletedA Study of Venetoclax in Combination With Bendamustine + Rituximab or Bendamustine + Obinutuzumab in Participa
Chronic Lymphocytic Leukemia
Phase 12014-01-13
CompletedA Study of Crenezumab Versus Placebo in Preclinical Presenilin1 (PSEN1) E280A Mutation Carriers to Evaluate Ef
Alzheimer's Disease
Phase 22013-12-20
CompletedA Study of GDC-0853 in Patients With Resistant B-Cell Lymphoma or Chronic Lymphocytic Leukemia.
Lymphocytic Leukemia, Chronic, Diffuse Large B-Cell Lymphoma
Phase 12013-12-16
CompletedA Study to Evaluate the Safety and Pharmacology of DNIB0600A in Participants With Platinum-Sensitive Ovarian C
Non-Squamous Non-Small Cell Lung Cancer
Phase 12013-12-16
CompletedA Study of Quilizumab Versus Placebo in Patients With Refractory Chronic Spontaneous Urticaria
Urticaria
Phase 22013-12-01
CompletedA Study of Polatuzumab Vedotin in Combination With Rituximab or Obinutuzumab, Cyclophosphamide, Doxorubicin, a
Lymphoma, Non Hodgkin
Phase 1 / Phase 22013-11-29
CompletedA Study of MHAA4549A in Healthy Volunteers in an Influenza Challenge Model
Healthy Volunteer
Phase 22013-11-25
CompletedA Study to Evaluate the Effect of Particle Size, Formulation and Food on the Pharmacokinetics of GDC-0032 in H
Healthy Volunteer
Phase 12013-11-01
CompletedA Bioavailability and Pharmacokinetic Study of GDC-0032 in Healthy Volunteers
Healthy Volunteer
Phase 12013-11-01
CompletedA Study of MEHD7945A and Cobimetinib in Patients With Locally Advanced or Metastatic Cancers With Mutant KRAS
Neoplasms
Phase 12013-11-01
CompletedSafety and Tolerability of Pirfenidone in Participants With Systemic Sclerosis-Related Interstitial Lung Disea
Systemic Sclerosis
Phase 22013-10-01
CompletedA Study of MEHD7945A in Combination With Cisplatin and 5-Fluorouracil (5-FU) or Paclitaxel and Carboplatin in
Head and Neck Cancer
Phase 12013-09-19
CompletedA Study of Ipatasertib (GDC-0068) in Combination With Fluoropyrimidine Plus Oxaliplatin in Participants With A
Gastric Cancer
Phase 22013-08-14
CompletedAn Expanded Access, Open-Label Study of Obinutuzumab (GA101) Plus Chlorambucil in Patients With Previously Unt
Chronic Lymphocytic Leukemia
Phase 22013-08-01
CompletedA Dose-escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics of GDC-0032 in Combination Wi
Breast Cancer, Non-small Lung Cancer
Phase 12013-07-16
CompletedA Study to Evaluate Effect of Itraconazole on the Pharmacokinetics of Cobimetinib in Healthy Participants
Healthy Participants
Phase 12013-07-01
CompletedA Study of MHAA4549A to Assess Safety And Pharmacokinetics in Healthy Volunteers
Healthy Volunteer
Phase 12013-07-01
CompletedA Dose-Escalation Study of GDC-0994 in Patients With Locally Advanced or Metastatic Solid Tumors
Solid Tumor
Phase 12013-06-21
CompletedA Study of Atezolizumab in Participants With Programmed Death-Ligand 1 (PD-L1) Positive Locally Advanced or Me
Non-Small Cell Lung Cancer
Phase 22013-05-30
CompletedA Drug Interaction Study of GDC-0032 Co-administered With Rifampin or Itraconazole in Healthy Volunteers
Healthy Volunteer
Phase 12013-04-01
CompletedA Study of Paclitaxel With GDC-0941 Versus Paclitaxel With Placebo in Participants With Locally Recurrent or M
Breast Cancer
Phase 22013-02-06
CompletedA Drug-Drug Interaction Study of the Effect of Rabeprazole, Itraconazole or Fluconazole on the Pharmacokinetic
Healthy Volunteer
Phase 12013-02-01
CompletedA Study of MCMV5322A/MCMV3068A for the Prevention of Cytomegalovirus Disease in High-Risk Kidney Allograft Rec
Cytomegalovirus Infections
Phase 22012-12-14
CompletedA Long-Term Safety Extension of Studies ABE4869g and ABE4955g in Participants With Mild to Moderate Alzheimer'
Alzheimer's Disease
Phase 22012-12-07
CompletedThe Management of Schizophrenia in Clinical Practice (MOSAIC)
Schizophrenia
2012-12-01
CompletedA Study of the Comparable Efficacy and Safety of Pulmozyme (Dornase Alfa) Delivered by the eRapid Nebulizer Sy
Cystic Fibrosis
Phase 42012-12-01
CompletedA Screening Study to Detect BRAF V600 Mutation-Positive Patients For Enrollment Into Clinical Research Studies
Multiple Myeloma, Neoplasms
2012-12-01
CompletedA Study of Venetoclax in Combination With Obinutuzumab in Participants With Chronic Lymphocytic Leukemia
Lymphocytic Leukemia, Chronic
Phase 12012-11-29
RecruitingThe Mycophenolate Pregnancy Registry
Heart Transplantation, Kidney Transplantation, Liver Transplantation, Autoimmune Diseases
2012-11-20
CompletedSafety and Efficacy Study of MEHD7945A + FOLFIRI Versus Cetuximab + FOLFIRI as Second Line Therapy in Particip
Colorectal Cancer
Phase 22012-10-01
CompletedA Study of Pinatuzumab Vedotin (DCDT2980S) Combined With Rituximab or Polatuzumab Vedotin (DCDS4501A) Combined
Follicular Lymphoma, Diffuse Large B-Cell Lymphoma
Phase 1 / Phase 22012-09-27
CompletedA Pharmacokinetics Study of Radioactive-Labeled GDC-0973 in Healthy Male Volunteers
Healthy Volunteer
Phase 12012-09-01
CompletedA Phase 1b Study of Atezolizumab in Combination With Vemurafenib or Vemurafenib Plus Cobimetinib in Participan
Malignant Melanoma
Phase 12012-08-13
CompletedA Long-Term Extension Study of WA22762 and NA25220 of Subcutaneous (SC) Tocilizumab (TCZ) in Moderate to Sever
Rheumatoid Arthritis
Phase 32012-08-01
CompletedA Study of Atezolizumab Administered in Combination With Bevacizumab and/or With Chemotherapy in Participants
Cancer
Phase 12012-07-11
CompletedA Study of MEHD7945A Versus Cetuximab in Patients With Recurrent/Metastatic Squamous Cell Carcinoma of The Hea
Head and Neck Cancer
Phase 22012-07-01
CompletedAn Observational Study of The Safety of MabThera/Rituxan (Rituximab) in Participants With Granulomatosis With
Granulomatosis With Polyangiitis, Microscopic Polyangiitis
2012-06-20
TerminatedAn Observational Study of Treatment Patterns and Effectiveness and Safety Outcomes in Advanced Basal Cell Carc
Basal Cell Carcinoma
2012-06-20
CompletedAn Observational Study in Patients With HER2 Positive Metastatic Breast Cancer (SystHERs Registry)
Breast Cancer
2012-06-05
TerminatedAn Extension Study to Evaluate the Long-Term Safety of Lampalizumab in Participants With Geographic Atrophy
Geographic Atrophy
Phase 22012-05-29
CompletedA Phase II Study of the Safety and Efficacy of MPSK3169A in Patients With Coronary Heart Disease or High Risk
Coronary Heart Disease
Phase 22012-05-01
CompletedA Study of GDC-0084 in Patients With Progressive or Recurrent High-Grade Glioma
Glioblastoma, Glioma
Phase 12012-04-01
CompletedA Study of MEMP1972A in Patients With Allergic Asthma Inadequately Controlled on Inhaled Steroids And A Second
Asthma
Phase 22012-04-01
CompletedA Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0973 in Combination With GDC-0068 Whe
Neoplasms
Phase 12012-04-01
CompletedA Study of Onartuzumab (MetMAb) in Combination With Bevacizumab (Avastin) Plus Platinum And Paclitaxel or With
Non-Squamous Non-Small Cell Lung Cancer
Phase 22012-04-01
CompletedA Study of Onartuzumab (MetMAb) Versus Placebo in Combination With Paclitaxel Plus Platinum in Patients With S
Non-Squamous Non-Small Cell Lung Cancer
Phase 22012-04-01
CompletedA Study of GDC-0575 Alone and in Combination With Gemcitabine in Participants With Refractory Solid Tumors or
Lymphoma, Solid Tumor
Phase 12012-03-23
CompletedA Study of Vismodegib in Patients With Advanced Solid Malignancies Including Hepatocellular Carcinoma With Var
Cancer
Phase 12012-03-01
CompletedA Study of Lebrikizumab in Patients Whose Asthma is Uncontrolled With Inhaled Corticosteroids and A Second Con
Asthma
Phase 22012-03-01
CompletedA Study of MCAF5352A in Healthy Volunteers
Healthy Volunteer
Phase 12012-03-01
CompletedAn Observational Pilot Study Evaluating the Feasibility of Conducting Genome-Wide Association Studies Utilizin
Breast Cancer, Colorectal Cancer, Non-Small Cell Lung Cancer
2012-03-01
CompletedA Study of DEDN6526A in Patients With Metastatic or Unresectable Melanoma
Malignant Melanoma
Phase 12012-03-01
CompletedA Study of Lebrikizumab in Patients With Uncontrolled Asthma Who Are on Inhaled Corticosteroids and A Second C
Asthma
Phase 22012-03-01
CompletedSafety and Efficacy of Carboplatin/Paclitaxel and Carboplatin/Paclitaxel/Bevacizumab With and Without Pictilis
Non-Small Cell Lung Cancer
Phase 22012-01-20
CompletedStudy of Ipatasertib or Apitolisib With Abiraterone Acetate Versus Abiraterone Acetate in Participants With Ca
Prostate Cancer
Phase 1 / Phase 22012-01-11
CompletedA Study of RG7667 in Healthy Volunteers
Healthy Volunteer
Phase 12012-01-01
CompletedA Study of Onartuzumab (MetMAb) in Combination With Tarceva (Erlotinib) in Participants With Met Diagnostic-Po
Non-Squamous Non-Small Cell Lung Cancer
Phase 32012-01-01
CompletedStudy to Investigate the Safety, Pharmacokinetics, and Immunogenicity of Subcutaneous MCAF5352A in Healthy Vol
Healthy Volunteer
Phase 12011-12-01
CompletedStudy to Investigate the Absorption, Metabolism, and Excretion of [14C]-GDC-0980 Following Single Oral Dose Ad
Healthy Volunteer
Phase 12011-12-01
CompletedA Study of GDC-0980 in the Treatment of Recurrent or Persistent Endometrial Carcinoma
Endometrial Carcinoma
Phase 22011-12-01
CompletedStudy to Evaluate the Long-term Safety of Etrolizumab in Participants With Moderate to Severe Ulcerative Colit
Ulcerative Colitis
Phase 22011-11-29
CompletedA Study of DMOT4039A in Participants With Unresectable Pancreatic or Platinum-Resistant Ovarian Cancer
Ovarian Cancer
Phase 12011-11-01
CompletedStudy to Determine the Effect of Ketoconazole on the Pharmacokinetics of GDC-0980
Healthy Volunteer
Phase 12011-11-01
CompletedA Study Evaluating the Efficacy and Safety of MEGF0444A Dosed to Progression in Combination With Bevacizumab a
Metastatic Colorectal Cancer
Phase 22011-11-01
TerminatedStudy Of Zelboraf (Vemurafenib) in Patients With Locally-Advanced, Unresectable, Stage IIIc Or Metastatic Mela
Malignant Melanoma
Phase 22011-10-31
CompletedA Study Comparing Obinutuzumab (RO5072759; GA101) 1000 Milligram (mg) Versus 2000 mg in Participants With Prev
Lymphocytic Leukemia, Chronic
Phase 22011-10-31
WithdrawnA Study of Navitoclax in Addition to Bendamustine and Rituximab in Patients With Relapsed Diffuse Large B-Cell
Diffuse Large B-Cell Lymphoma
Phase 22011-10-01
CompletedStudy to Investigate the Absorption, Metabolism, and Excretion of [14C]-GDC-0941 Following Single Oral Dose Ad
Healthy Volunteer
Phase 12011-10-01
CompletedStudy of GDC-0941 or GDC-0980 With Fulvestrant Versus Fulvestrant in Advanced or Metastatic Breast Cancer in P
Breast Cancer
Phase 22011-10-01
CompletedStudy of GDC-0980 Versus Everolimus in Participants With Metastatic Renal Cell Carcinoma Who Have Progressed o
Renal Cell Carcinoma
Phase 22011-10-01
CompletedFOLFOX/Bevacizumab With Onartuzumab (MetMAb) Versus Placebo as First-Line Treatment in Patients With Metastati
Colorectal Cancer
Phase 22011-09-14
CompletedA Study of the Safety and Pharmacology of GDC-0980 in Combination With Either Paclitaxel and Carboplatin (With
Solid Cancers
Phase 12011-09-01
CompletedA Study of DFRF4539A in Patients With Relapsed or Refractory Multiple Myeloma
Multiple Myeloma
Phase 12011-09-01
CompletedEvaluate the Efficacy and Safety of rhuMAb Beta7 in Patients With Moderate to Severe Ulcerative Colitis
Ulcerative Colitis
Phase 22011-09-01
CompletedA Study to Evaluate the Impact of MABT5102A on Brain Amyloid Load and Related Biomarkers in Patients With Mild
Alzheimer's Disease
Phase 22011-08-31
CompletedA Study of Obinutuzumab [RO5072759 (GA101)] in Combination With CHOP Chemotherapy in Patients With Previously
Lymphoma, B-Cell
Phase 22011-08-31
CompletedStudy of Bevacizumab + mFOLFOX6 Versus Bevacizumab + FOLFIRI With Biomarker Stratification in Participants Wit
Colorectal Cancer
Phase 22011-08-01
CompletedA Study of Lebrikizumab in Healthy Japanese and Caucasian Volunteers
Healthy Volunteer
Phase 12011-08-01
CompletedTrial Evaluating the Safety and Pharmacokinetics of MFGR1877S in Patients With Advanced Solid Tumors
Solid Tumor
Phase 12011-08-01
CompletedSafety and Clinical Pharmacology of GDC-0068 in Combination With Docetaxel, Fluoropyrimidine Plus Oxaliplatin,
Neoplasms
Phase 12011-07-11
CompletedA Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0425 Administered With and Without Ge
Solid Tumor
Phase 12011-07-11
CompletedGDC-0980 in Combination With a Fluoropyrimidine, Oxaliplatin, and Bevacizumab in Patients With Advanced Solid
Solid Cancers
Phase 12011-07-01
CompletedA Study of Atezolizumab (an Engineered Anti-Programmed Death-Ligand 1 [PDL1] Antibody) to Evaluate Safety, Tol
Tumors, Hematologic Malignancies
Phase 12011-06-21
CompletedSafety and Pharmacokinetics of Escalating Doses of DNIB0600A in Participants With Non-Small Cell Lung Cancer (
Non-Small Cell Lung Cancer, Ovarian Cancer
Phase 12011-06-14
CompletedEvaluating the Safety and Tolerability of GDC-0349 in Patients With Locally Advanced or Metastatic Solid Tumor
Non-Hodgkin's Lymphoma, Solid Tumor
Phase 12011-06-01
CompletedPatient Reported Symptoms in Ovarian Cancer (PRECISION)
Ovarian Cancer
2011-06-01
CompletedEfficacy and Safety of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Idiopathic Pulmonary Fibrosis
Phase 32011-06-01
CompletedStudy Evaluating the Safety and Efficacy of MEGF0444A in Combination With Carboplatin, Paclitaxel and Bevacizu
Non-Squamous Non-Small Cell Lung Cancer
Phase 22011-06-01
CompletedA Study of Obinutuzumab (GA101; RO5072759) in Combination With Chemotherapy in Participants With Previously Un
Lymphocytic Leukemia, Chronic
Phase 12011-05-01
CompletedA Study to Evaluate the Efficacy and Safety of MABT5102A in Patients With Mild to Moderate Alzheimer's Disease
Alzheimer's Disease
Phase 22011-04-30
CompletedSafety and Pharmacokinetics of DMUC5754A Administered Intravenously to Patients With Platinum-Resistant Ovaria
Ovarian Cancer, Pancreatic Cancer
Phase 12011-04-01
CompletedA Study of Escalating Doses of Polatuzumab Vedotin in Participants With Relapsed or Refractory B-Cell Non-Hodg
Non-Hodgkins Lymphoma, Chronic Lymphocytic Leukemia
Phase 12011-03-22
TerminatedA Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Participants With Locally Advanc
Solid Cancers, Non-Hodgkin's Lymphoma
Phase 12011-03-16
CompletedA Study to Evaluate the Efficacy, Response Duration and Safety of Xolair (Omalizumab) in Patients With Chronic
Chronic Idiopathic Urticaria
Phase 32011-03-01
CompletedStudy Evaluating the Safety and Efficacy of Onartuzumab And/or Bevacizumab in Combination With Paclitaxel in P
Breast Cancer
Phase 22011-03-01
CompletedA Study of the Safety and Pharmacokinetics of Escalating Doses of DSTP3086S in Patients With Metastatic Castra
Prostate Cancer
Phase 12011-03-01
CompletedA Study of Safety, Tolerability, and Evidence of Activity of FCFD4514S Administered Monthly or Every Other Mon
Geographic Atrophy
Phase 22011-02-01
CompletedA Safety Study of Xolair (Omalizumab) in Patients With Chronic Idiopathic Urticaria (CIU) Who Remain Symptomat
Chronic Idiopathic Urticaria
Phase 32011-02-01
CompletedA Study of the Efficacy and Safety of Omalizumab (Xolair) in Patients With Chronic Idiopathic Urticaria (CIU)/
Chronic Idiopathic Urticaria
Phase 32011-02-01
CompletedA Study Evaluating Dosing Regimens for Treatment With Intravitreal Ranibizumab Injections in Subjects With Mac
Macular Edema
Phase 42011-02-01
CompletedA Study to Evaluate the Effect of a Proton-Pump Inhibitor (Rabeprazole) on the Relative Bioavailability of Cob
Healthy Volunteer
Phase 12011-01-01
CompletedA Study of Relative Bioavailability and Food Effect Study of Cobimetinib in Healthy Participants
Healthy Volunteers
Phase 12010-12-01
CompletedStudy of the Safety and Pharmacology of GDC-0980 in Combination With Paclitaxel With or Without Bevacizumab in
Breast Cancer
Phase 12010-12-01
CompletedA Study of MEMP1972A in the Prevention of Allergen-Induced Airway Obstruction in Patients With Mild Asthma (SO
Asthma
Phase 22010-12-01
CompletedA Study of the Safety and Pharmacokinetics (PK) of MEHD7945A in Participants With Locally Advanced or Metastat
Epithelial Tumors, Malignant
Phase 12010-11-09
CompletedA Study of the Safety and Pharmacokinetics of MFGR1877S in Patients With Relapsed or Refractory t(4;14)-Positi
Multiple Myeloma
Phase 12010-11-01
CompletedA Study of Pharmacokinetic Drug Interaction Study of the Hedgehog Pathway Inhibitor GDC-0449 in Combination Wi
Solid Cancers
Phase 12010-11-01
CompletedAn Absolute Bioavailability Study in Healthy Participants Comparing Oral to Intravenous Administration of GDC-
Healthy Volunteers
Phase 12010-11-01
TerminatedA Study to Evaluate Growth in Participants Treated With Somatropin (Nutropin) Using NuSpin Device
Growth Hormone Deficiency
2010-11-01
CompletedA Study to Evaluate the Efficacy and Safety of MLTA3698A in Combination With a Disease-Modifying Anti-Rheumati
Rheumatoid Arthritis
Phase 22010-11-01
CompletedA Study to Determine the Relative Bioavailability of a Tablet Formulation of GDC-0941 and the Effect of Ketoco
Healthy Volunteer
Phase 12010-11-01
CompletedA 3-Part Study to Determine the Relative Bioavailability of Capsule and Tablet Formulations of GDC-0980, the E
Healthy Volunteer
Phase 12010-10-14
CompletedA Study Evaluating the Safety, Tolerability and Pharmacokinetics of GDC-0917 Administered to Patients With Ref
Solid Cancers
Phase 12010-10-01
CompletedA Study Evaluating the Efficacy and Safety of Vismodegib (GDC-0449) in Operable Basal Cell Carcinoma
Basal Cell Carcinoma
Phase 22010-10-01
CompletedA Study of the Safety and Pharmacokinetics of Escalating Doses of DCDT2980S in Patients With Relapsed or Refra
Non-Hodgkin's Lymphoma, Chronic Lymphocytic Leukemia
Phase 12010-10-01
CompletedA Study of the Effects of RoActemra/Actemra on Vaccination in Patients With Rheumatoid Arthritis on Background
Rheumatoid Arthritis
Phase 42010-09-01
CompletedA Study to Investigate the Effect of GDC-0449 on the QT/QTc Interval in Healthy Female Subjects
Healthy Volunteer
Phase 12010-08-25
CompletedA Study of ABT-263 in Combination With Dose-Intensive Rituximab, or Dose-Intensive Rituximab Alone, in Previou
Chronic Lymphocytic Leukemia
Phase 22010-08-01
CompletedA Study to Investigate the Safety, Tolerability, and Pharmacokinetics of MEMP1972A in Patients With Allergic R
Allergic Rhinitis
Phase 12010-07-11
Approved For MarketingA Study of Vismodegib (GDC-0449) in Patients With Locally Advanced or Metastatic Basal Cell Carcinoma
Basal Cell Carcinoma
2010-07-01
CompletedA Study of the Safety and Pharmacokinetics of MINT1526A, Administered Intravenously As a Single Agent and in C
Solid Cancers
Phase 12010-06-01
CompletedA Study Evaluating the Persistency of Response With or Without Xolair (Omalizumab) After Long-term Therapy
Allergic Asthma
Phase 42010-05-01
No Longer AvailableA Study of Trastuzumab-MCC-DM1 in Patients With HER2- Positive Locally Advanced or Metastatic Breast Cancer
Metastatic Breast Cancer
2010-05-01
CompletedA Study to Investigate the Efficacy and Safety of Bendamustine Compared With Bendamustine+Obinutuzumab (GA101)
Non-Hodgkin's Lymphoma
Phase 32010-04-30
CompletedA Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0623 in Patients With Locally Advance
Solid Cancers
Phase 12010-04-01
CompletedA Study Evaluating the Safety and Tolerability of GDC-0068 in Patients With Refractory Solid Tumors
Solid Cancers
Phase 12010-03-01
CompletedA Study to Evaluate the Safety, Tolerability, and Activity of Intravenous MLDL1278A in Patients on Standard-of
Atherosclerosis
Phase 22010-03-01
CompletedA Study of the Safety and Pharmacology of MEGF0444A in Combination With Bevacizumab With or Without Paclitaxel
Solid Cancers
Phase 12010-02-01
CompletedA Study to Evaluate Lebrikizumab (MILR1444A) in Adult Patients With Asthma Who Are Not Taking Inhaled Corticos
Asthma
Phase 22009-11-01
TerminatedSafety, Tolerability and Pharmacokinetics of Cobimetinib in Combination With Pictilisib in Patients With Local
Solid Tumors
Phase 12009-11-01
CompletedA Study to Determine the Relative Bioavailability of Capsule and Tablet Formulations of GDC-0941 and the Effec
Healthy Volunteers
Phase 12009-10-26
CompletedA Study of the Safety, Tolerability, Pharmacokinetics, and Bioavailability of IV and SC MABT5102A in Healthy V
Healthy Volunteer
Phase 12009-10-01
CompletedA Study of the Safety and Pharmacology Of PI3-Kinase Inhibitor GDC-0941 In Combination With Either Paclitaxel
Non-Squamous Non-Small Cell Lung Cancer
Phase 12009-10-01
CompletedA Study of Vismodegib (GDC-0449) in Patients Treated With Vismodegib in a Previous Genentech-sponsored Phase I
Ovarian Cancer, Basal Cell Carcinoma, Metastatic Colorectal Cancer
Phase 22009-09-01
CompletedA Study of the Safety and Pharmacology of GDC-0941 in Combination With Erlotinib in Patients With Advanced Sol
Non-Squamous Non-Small Cell Lung Cancer, Solid Cancers
Phase 12009-09-01
CompletedA Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Intravitreal Injections of FCFD45
Geographic Atrophy
Phase 12009-09-01
CompletedA Study of the Hedgehog Pathway Inhibitor GDC-0449 in Healthy Female Subjects of Non-Childbearing Potential
Healthy
Phase 12009-09-01
CompletedA Study of huMAb OX40L in the Prevention of Allergen-Induced Airway Obstruction in Adults With Mild Allergic A
Asthma
Phase 22009-09-01
CompletedA Study of Hedgehog Pathway Inhibitor GDC-0449 in Patients With Locally Advanced or Metastatic Solid Tumors Th
Solid Cancers
Phase 12009-09-01
CompletedA Study to Evaluate the Efficacy and Safety of Rontalizumab in Patients With Moderately to Severely Active Sys
Systemic Lupus Erythematosus
Phase 22009-09-01
CompletedA Study of Trastuzumab Emtansine, Paclitaxel, and Pertuzumab in Patients With HER2-Positive, Locally Advanced
Metastatic Breast Cancer
Phase 1 / Phase 22009-08-01
CompletedA Study of PI3-Kinase Inhibitor GDC-0941 in Combination With Paclitaxel, With and Without Bevacizumab or Trast
Breast Cancer
Phase 12009-08-01
CompletedA Study of MNRP1685A in Combination With Bevacizumab With or Without Paclitaxel in Patients With Locally Advan
Solid Cancers
Phase 12009-08-01
CompletedTrastuzumab and Trastuzumab-MCC-DM1 Administered Intravenously and GDC-0941 Administered Orally to Patients Wi
Metastatic Breast Cancer
Phase 12009-07-01
CompletedA Study to Evaluate Corrected QT Interval and Drug-Drug Interaction of Trastuzumab on Carboplatin in the Prese
Solid Cancers
Phase 12009-07-01
CompletedCorrected QT Interval Effects of Trastuzumab Emtansine (T-DM1) in Patients With Human Epidermal Growth Factor
Metastatic Breast Cancer
Phase 22009-07-01
CompletedA Study of Ranibizumab Administered Monthly or on an As-needed Basis in Patients With Subfoveal Neovascular Ag
Age-related Macular Degeneration
Phase 32009-07-01
CompletedA Study of Lebrikizumab (MILR1444A) in Adult Patients With Asthma Who Are Inadequately Controlled on Inhaled C
Asthma
Phase 22009-07-01
CompletedA Study of the Safety and Pharmacokinetics of MEGF0444A Administered to Patients With Advanced Solid Tumors
Solid Cancers
Phase 12009-05-22
CompletedA Study of PRO95780 Administered in Combination With the FOLFOX Regimen and Bevacizumab in Patients With Previ
Metastatic Colorectal Cancer
Phase 12009-05-01
CompletedA Study of the Safety and Pharmacokinetics of PRO283698 in Patients With Rheumatoid Arthritis
Rheumatoid Arthritis
Phase 12009-05-01
CompletedA Study Evaluating GDC-0980 Administered Once Weekly in Patients With Refractory Solid Tumors or Non-Hodgkin's
Non-Hodgkin's Lymphoma, Solid Cancers
Phase 12009-05-01
CompletedA Study of Dulanermin Administered in Combination With the FOLFOX Regimen and Bevacizumab in Patients With Pre
Metastatic Colorectal Cancer
Phase 12009-05-01
CompletedA Study of MetMAb Administered to Patients With Advanced Non-Small Cell Lung Cancer, in Combination With Tarce
Non-Small Cell Lung Cancer
Phase 22009-04-01
TerminatedA Study to Evaluate Ocrelizumab in Combination With Methotrexate Compared With Infliximab Plus Methotrexate in
Rheumatoid Arthritis
Phase 22009-03-05
CompletedA Study of the Combination of Erlotinib and Pertuzumab in Patients With Relapsed Non-small Cell Lung Cancer
Non-Small Cell Lung Cancer
Phase 22009-03-01
CompletedA Study Evaluating GDC-0980 Administered Once Daily in Patients With Refractory Solid Tumors or Non-Hodgkin's
Non-Hodgkin's Lymphoma, Solid Cancers
Phase 12009-03-01
CompletedA Study of Xolair (Omalizumab) in Patients With Chronic Idiopathic Urticaria (CIU) Who Remain Symptomatic With
Chronic Idiopathic Urticaria
Phase 22009-03-01
CompletedPharmacosurveillance Data Repository of Patients With and Without History of Anaphylactic Reactions Subsequent
Allergic Asthma
2009-03-01
CompletedA Study Evaluating the Efficacy and Safety of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) in Patients Wi
Basal Cell Carcinoma
Phase 22009-02-01
CompletedA Study of Pregnancy and Pregnancy Outcomes in Women With Breast Cancer Treated With Trastuzumab, Pertuzumab i
Breast Cancer, Pregnancy
2009-01-14
CompletedA Study of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) As Maintenance Therapy in Patients With Ovarian C
Ovarian Cancer
Phase 22008-12-01
CompletedA Study to Evaluate MILR1444A in the Prevention of Allergen-Induced Airway Obstruction in Adults With Mild All
Allergic Asthma
Phase 22008-12-01
Active Not RecruitingA Safety Extension Study of Trastuzumab Emtansine in Participants Previously Treated With Trastuzumab Emtansin
Neoplasm Metastasis
Phase 22008-10-16
SuspendedA Study of D4064A Administered to Patients With Recurrent or Persistent Epithelial Ovarian, Primary Peritoneal
Fallopian Tube Cancer, Ovarian Cancer, Peritoneal Cancer
Phase 12008-09-01
CompletedA Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of rhuMAb Beta7 in Patien
Ulcerative Colitis
Phase 12008-09-01
CompletedA Study of MNRP1685A in Patients With Locally Advanced or Metastatic Solid Tumors
Solid Cancers
Phase 12008-09-01
CompletedOpen-Label Study of the Long Term Safety of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Idiopathic Pulmonary Fibrosis
Phase 32008-08-01
CompletedA Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Anti-Abeta (MABT5102A) in Pat
Alzheimer's Disease
Phase 12008-08-01
CompletedA Study of Trastuzumab-Mcc-DM1 Administered Intravenously to Patients With HER2-Positive Metastatic Breast Can
Metastatic Breast Cancer
Phase 22008-08-01
CompletedThe Safety and Utility of Skin Testing With XOLAIR® (Omalizumab) and Placebo Omalizumab (Formulation Excipient
Healthy, Asthma
Phase 42008-08-01
CompletedA Study of the Efficacy and Safety of Ocrelizumab in Patients With Relapsing-Remitting Multiple Sclerosis
Multiple Sclerosis, Relapsing-Remitting
Phase 22008-07-17
CompletedAn Extension Study to Evaluate Safety and Tolerability of Ranibizumab in Macular Edema Secondary to Retinal Ve
Macular Edema, Retinal Vein Occlusion
N/A2008-07-01
CompletedA Study of Rituximab Alternative Dosing Rate in Patients With Previously Untreated Diffuse Large B-cell or Fol
Non-Hodgkin's Lymphoma
Phase 32008-07-01
TerminatedA Study of the Safety, Pharmacokinetics, and Pharmacodynamics of MTRX1011A in Patients With Rheumatoid Arthrit
Rheumatoid Arthritis
Phase 12008-07-01
TerminatedA Study of Pulmozyme® (Dornase Alpha) in 3- to 5-Year-Old Patients With Cystic Fibrosis
Cystic Fibrosis
Phase 42008-06-01
CompletedAn Observational Study of Treatment Patterns and Safety Outcomes for Metastatic or Locally Recurrent Breast Ca
Breast Cancer
2008-06-01
CompletedA Study of the Safety and Pharmacology of SGN-40 Administered in Combination With Bortezomib in Patients With
Multiple Myeloma
Phase 12008-05-01
CompletedA Study of Vismodegib (GDC-0449, Hedgehog Pathway Inhibitor) With Concurrent Chemotherapy and Bevacizumab As F
Metastatic Colorectal Cancer
Phase 22008-05-01
TerminatedA Study to Evaluate Ocrelizumab Compared With Placebo in Patients With Rheumatoid Arthritis Who Have an Inadeq
Rheumatoid Arthritis
Phase 32008-04-24
CompletedA Study of PRO95780 in Combination With Rituximab in Patients With Non-Hodgkin's Lymphoma That Has Progressed
Non-Hodgkin's Lymphoma
Phase 22008-03-01
CompletedA Study of GDC-0941 in Patients With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma for
Non-Hodgkin's Lymphoma, Solid Cancers
Phase 12008-03-01
TerminatedA Study to Evaluate Ocrelizumab in Patients With Nephritis Due to Systemic Lupus Erythematosus (BELONG)
Lupus Nephritis, Systemic Lupus Erythematosus
Phase 32008-02-15
CompletedA Study to Evaluate Pertuzumab + Trastuzumab + Docetaxel vs. Placebo + Trastuzumab + Docetaxel in Previously U
Metastatic Breast Cancer
Phase 32008-02-12
CompletedA Study to Evaluate the Safety and Efficacy of Efalizumab in Adult Patients With Moderate to Severe Plaque Pso
Psoriasis
Phase 42008-02-01
TerminatedA Study to Evaluate Two Doses of Ocrelizumab in Patients With Active Systemic Lupus Erythematosus (BEGIN)
Systemic Lupus Erythematosus
Phase 32007-12-19
CompletedA Study of SGN-40 in Combination With Rituximab in Patients With CD20-Positive, Follicular and Marginal Zone B
Non-Hodgkin's Lymphoma
Phase 12007-12-01
CompletedA Study of GDC-0941 in Participants With Locally Advanced or Metastatic Solid Tumors for Which Standard Therap
Solid Cancers
Phase 12007-10-01
CompletedA Study of PRO95780 in Combination With Cetuximab and Irinotecan Chemotherapy or the FOLFIRI Regimen With Beva
Colorectal Cancer
Phase 12007-10-01
CompletedA Study of Omalizumab in the Prevention of Allergen Induced Airway Obstruction in Adults With Mild Allergic As
Allergic Asthma
Phase 22007-10-01
CompletedA Study of Omalizumab in Preventing Bronchoconstriction Following Environmental Cat Dander Exposure in Patient
Asthma
Phase 42007-09-01
CompletedA Study of Bevacizumab in Combination With Capecitabine and Cisplatin as First-line Therapy in Patients With A
Adenocarcinoma
Phase 32007-09-01
TerminatedA Trial of the Safety of Escalating Doses of PRO131921 in Patients With Relapsed or Refractory Chronic Lymphoc
Chronic Lymphocytic Leukemia
Phase 1 / Phase 22007-08-27
TerminatedA Study Evaluating the Efficacy and Safety of Sunitinib With or Without Bevacizumab in First-Line Patients Wit
Renal Cell Carcinoma
Phase 22007-08-01
CompletedA Study of the Safety and Pharmacology of MetMAb (PRO143966), a Monovalent Antagonist Antibody to the Receptor
Solid Cancers
Phase 12007-08-01
CompletedA Study of the Efficacy and Safety of Ranibizumab Injection in Patients With Macular Edema Secondary to Centra
Macular Edema, Retinal Vein Occlusion
Phase 32007-07-01
CompletedA Study of the Efficacy and Safety of Ranibizumab Injection in Patients With Macular Edema Secondary to Branch
Macular Edema, Retinal Vein Occlusion
Phase 32007-07-01
CompletedA Study of Trastuzumab Emtansine (Trastuzumab-MCC-DM1) Administered Intravenously to Patients With Human Epide
Metastatic Breast Cancer
Phase 22007-07-01
TerminatedA Study of Ocrelizumab in Combination With Methotrexate in Patients With Rheumatoid Arthritis Who Are Naive to
Rheumatoid Arthritis
Phase 32007-06-11
CompletedA Study of PRO95780 in Patients With Previously Untreated, Advanced-Stage Non-Small Cell Lung Cancer (APM4074g
Non-Small Cell Lung Cancer
Phase 22007-06-01
CompletedA Study of Ranibizumab Injection in Subjects With Clinically Significant Macular Edema (ME) With Center Involv
Diabetes Mellitus, Macular Edema
Phase 32007-06-01
CompletedA Study of Bevacizumab in Combination With Bortezomib in Patients With Relapsed or Refractory Multiple Myeloma
Multiple Myeloma
Phase 22007-06-01
TerminatedA Study of the Safety and Pharmacokinetics of GDC-0152, Administered Intravenously to Patients With Locally Ad
Solid Cancers
Phase 12007-06-01
WithdrawnA Study to Evaluate Corrected QT Interval From Clinical Studies Conducted With Bevacizumab
Carcinoma
2007-06-01
CompletedA Study of Ranibizumab Injection in Subjects With Clinically Significant Macular Edema (ME) With Center Involv
Diabetes Mellitus, Macular Edema
Phase 32007-06-01
TerminatedA Study of PRO95780 in Patients With Advanced Chondrosarcoma (APM4171g)
Chondrosarcoma
Phase 22007-05-31
TerminatedA Study of Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Who Don't Have a Respo
Rheumatoid Arthritis
Phase 32007-05-15
TerminatedA Trial of the Safety of Escalating Doses of PRO131921 in Patients With Relapsed or Refractory Indolent Non-Ho
Non-Hodgkin's Lymphoma
Phase 1 / Phase 22007-05-01
CompletedStudy of Cobimetinib in Participants With Solid Tumors
Solid Tumor
Phase 12007-05-01
CompletedA Study of Carboplatin and Gemcitabine Plus Bevacizumab in Patients With Ovary, Peritoneal, or Fallopian Tube
Ovarian Cancer
Phase 32007-04-01
CompletedGDC-0449 in Treating Patients With Locally Advanced or Metastatic Solid Tumors
Unspecified Adult Solid Tumor, Protocol Specific
Phase 12007-04-01
TerminatedA Study of Sunitinib in Combination With Bevacizumab and Paclitaxel in Previously Untreated Patients With Meta
Metastatic Breast Cancer
Phase 22007-03-01
TerminatedA Study of Sunitinib in Combination With Bevacizumab, Carboplatin, and Paclitaxel in Patients With Advanced No
Non-Small Cell Lung Cancer
Phase 22007-03-01
TerminatedA Trial of Pulmozyme Withdrawal on Exercise Tolerance in Cystic Fibrosis Subjects With Severe Lung Disease (TO
Cystic Fibrosis
Phase 42007-03-01
CompletedA Study of Bevacizumab in Previously Untreated Extensive-Stage Small Cell Lung Cancer (SALUTE)
Small Cell Lung Cancer
Phase 22007-03-01
CompletedA Study of rhuMAb IFNalpha in Adults With Systemic Lupus Erythematosus
Systemic Lupus Erythematosus
Phase 12007-02-01
CompletedA Study of Bevacizumab With Carboplatin and Paclitaxel Chemotherapy for the First-Line Treatment of Patients W
Melanoma
Phase 22007-02-01
CompletedA Study of the Safety of Rituxan in Patients With Rheumatoid Arthritis After an Inadequate Response to Previou
Rheumatoid Arthritis
2007-01-01
CompletedA Study of the Safety of Rituximab in Combination With Other Anti-Rheumatic Drugs in Subjects With Active Rheu
Rheumatoid Arthritis
Phase 32007-01-01
TerminatedA Study of Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexat
Rheumatoid Arthritis
Phase 32006-12-27
CompletedA Study of Tenecteplase for Restoration of Function in Dysfunctional Central Venous Catheters
Dysfunctional Central Venous Access Catheters
Phase 32006-12-01
CompletedA Study of Changes in FDG- and FLT-PET Imaging in Patients With Non-Small Cell Lung Cancer Following Treatment
Non-Small Cell Lung Cancer
Phase 1 / Phase 22006-12-01
CompletedA Study to Evaluate the Safety and Efficacy of HAE1 in Subjects With Moderate to Severe Allergic Asthma
Allergic Asthma
Phase 22006-12-01
CompletedA Study of Tenecteplase for Restoration of Function in Dysfunctional Hemodialysis (HD) Catheters
Dysfunctional Hemodialysis Catheters
Phase 32006-11-01
CompletedA Study of Tenecteplase for Restoration of Function in Dysfunctional Central Venous Catheters
Dysfunctional Central Venous Access Catheters
Phase 32006-11-01
CompletedA Study of Xolair in Peanut-Allergic Subjects Previously Enrolled in Study Q2788g
Peanut Hypersensitivity
Phase 22006-11-01
CompletedA Study of Avastin in Combination With Chemotherapy for Treatment of Colorectal Cancer and Non-Small Cell Lung
Colorectal Cancer, Non-Small Cell Lung Cancer
2006-11-01
CompletedAn Observational Study of the Use and Safety of Xolair® During Pregnancy
Asthma
2006-10-20
CompletedA Study of Tenecteplase for Restoration of Function in Dysfunctional Hemodialysis Catheters
Dysfunctional Hemodialysis Catheters
Phase 32006-10-01
CompletedThree-Arm Study of the Safety and Efficacy of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis
Idiopathic Pulmonary Fibrosis
Phase 32006-07-14
CompletedA Study of Dulanermin Administered in Combination With Camptosar®/Erbitux® Chemotherapy or FOLFIRI (With or Wi
Colorectal Cancer
Phase 12006-07-01
CompletedA Study to Evaluate Bevacizumab Alone or in Combination With Irinotecan for Treatment of Glioblastoma Multifor
Glioblastoma
Phase 22006-07-01
TerminatedA Study to Evaluate the Safety of Rituximab Retreatment in Subjects With Systemic Lupus Erythematosus
Lupus Erythematosus, Systemic
Phase 32006-06-22
TerminatedA Study of Dulanermin in Combination With Rituximab in Subjects With Follicular and Other Low Grade, CD20+, No
Non-Hodgkin's Lymphoma
Phase 1 / Phase 22006-06-01
CompletedA Study to Evaluate Raptiva in Subjects With Chronic Moderate or Worse Plaque Psoriasis Who Have Had an Inadeq
Psoriasis
Phase 42006-05-01
CompletedA Study of Trastuzumab-MCC-DM1 Administered Intravenously to Patients With HER2-Positive Metastatic Breast Can
Metastatic Breast Cancer
Phase 12006-04-01
CompletedSafety and Efficacy of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis
Idiopathic Pulmonary Fibrosis
Phase 32006-04-01
CompletedA Study to Evaluate the Safety and Efficacy of Efalizumab in Adult Patients With Plaque Psoriasis Involving th
Psoriasis
Phase 42006-03-30
CompletedA Study of Bevacizumab in Combination With First- or Second-Line Therapy in Subjects With Treated Brain Metast
Non-Small Cell Lung Cancer, Brain Neoplasms
Phase 22006-03-01
CompletedA Study to Evaluate the Safety and Efficacy of Bevacizumab in Combination With Chemotherapy in Previously Trea
Metastatic Breast Cancer
Phase 32006-02-01
CompletedA Prospective, Randomized, Double-Blind Study of the Efficacy of Omalizumab (Xolair) in Atopic Asthmatics With
Asthma
Phase 42006-02-01
CompletedA Study to Evaluate the Effects of Rituximab on Immune Responses in Subjects With Active Rheumatoid Arthritis
Rheumatoid Arthritis
Phase 22006-01-23
CompletedA Study to Evaluate Rituximab in Combination With Methotrexate in Methotrexate-Naive Patients With Active Rheu
Rheumatoid Arthritis
Phase 32006-01-01
CompletedA Study Comparing Bevacizumab Therapy With or Without Erlotinib for First-Line Treatment of Non-Small Cell Lun
Non-Small Cell Lung Cancer
Phase 32006-01-01
CompletedA Study of Retreatment With Rituximab in Patients With Rheumatoid Arthritis Receiving Background Methotrexate
Rheumatoid Arthritis
Phase 32006-01-01
CompletedA Study to Evaluate the Efficacy and Safety of Rituximab in Subjects With International Society of Nephrology/
Lupus Nephritis
Phase 32006-01-01
CompletedA Study to Assess the Effect of Topical Recombinant Human Vascular Endothelial Growth Factor for Induction of
Foot Ulcer, Diabetic
Phase 22006-01-01
UnknownA Study Evaluating the Efficacy and Safety of Bevacizumab in Combination With Chemotherapy in Untreated Metast
Metastatic Breast Cancer
Phase 32005-12-01
CompletedA Study of Omalizumab (Xolair) in Subjects With Moderate to Severe Persistent Asthma (EXTRA)
Asthma
Phase 32005-12-01
CompletedA Study to Evaluate Ranibizumab in Subjects With Choroidal Neovascularization (CNV) Secondary to Age-Related M
Choroidal Neovascularization, Age-related Macular Degeneration
Phase 32005-11-01
TerminatedA Study of Intravenous INO-1001 Plus Oral Temozolomide to Evaluate Tolerability, Safety, and Pharmacokinetics
Melanoma
Phase 12005-10-01
CompletedA Study to Evaluate the Safety and Efficacy of Rituximab in Combination With Methotrexate Compared to Methotre
Rheumatoid Arthritis
Phase 32005-10-01
CompletedA Study of Bevacizumab Plus Carboplatin and Paclitaxel in Subjects With Advanced, Previously Untreated, Squamo
Non-small Cell Lung Cancer
Phase 22005-09-01
CompletedA Study of the Safety and Efficacy of Rituximab in Patients With Moderate to Severe Rheumatoid Arthritis Recei
Rheumatoid Arthritis
Phase 22005-08-01
CompletedA Study to Evaluate the Efficacy of Bevacizumab in Combination With Tarceva for Advanced Non-Small Cell Lung C
Non-Small Cell Lung Cancer
Phase 32005-06-08
CompletedA Study to Evaluate the Safety of Rituximab Retreatment in Subjects With Systemic Lupus Erythematosus
Lupus Erythematosus, Systemic
Phase 2 / Phase 32005-05-10
CompletedA Study to Evaluate Subjects Treated With rhuMab 2C4 (Pertuzumab) in a Previous Genentech Phase II Cancer Stud
Solid Cancers
Phase 22005-05-01
TerminatedA Study to Compare Two Avastin-Based Treatment Regimens for the Treatment of Metastatic Colorectal Cancer
Colorectal Cancer
Phase 42005-05-01
CompletedAn Extension Study to Evaluate the Safety and Tolerability of Ranibizumab in Subjects With Choroidal Neovascul
Choroidal Neovascularization, Age-related Macular Degeneration
N/A2005-04-01
CompletedA Study to Evaluate Psoriasis Outcomes and Safety Events in Patients With Chronic Moderate to Severe Plaque Ps
Psoriasis
2005-03-01
CompletedA Study of Bevacizumab in Ovarian Cancer or Primary Peritoneal Cancer Where Doxil or Topotecan Therapy Has Fai
Ovarian Cancer
Phase 22005-02-01
CompletedA Study to Evaluate rhuMab 2C4 and Gemcitabine in Subjects With Ovarian, Primary Peritoneal, or Fallopian Tube
Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer
Phase 22005-01-01
CompletedAn Observational Study of the Use and Safety of Raptiva During Pregnancy (FOLLOW)
Psoriasis, Pregnancy
2005-01-01
CompletedA Study to Evaluate Rituximab in Adults With Relapsing Remitting Multiple Sclerosis
Multiple Sclerosis
Phase 22004-12-01
CompletedA Study to Evaluate Tarceva in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)
Lung Cancer, Non-small-cell Lung Carcinoma
Phase 32004-08-01
CompletedA Study of rhuFab V2 (Ranibizumab) in Subjects With Subfoveal Choroidal Neovascularization Secondary to Age-Re
Macular Degeneration
Phase 32004-08-01
CompletedA Study to Evaluate Bevacizumab and Chemotherapy or Tarceva in Treating Recurrent or Refractory NSCLC (Non-Sma
Non-Small-Cell Lung Carcinoma, Neoplasm Recurrence, Local
Phase 22004-07-01
TerminatedA Safety and Efficacy Study of Xolair in Peanut Allergy
Allergy
Phase 22004-06-01
CompletedA Study to Evaluate the Safety and Efficacy of Rituximab in Adults With Primary Progressive Multiple Sclerosis
Multiple Sclerosis
Phase 2 / Phase 32004-06-01
CompletedA Study of Xolair to Evaluate Effectiveness and Long-Term Safety in Patients With Moderate to Severe Asthma
Asthma
2004-06-01
CompletedA Study of Avastin With Chemotherapy for Treatment of Metastatic or Advanced and Unresectable Colorectal Adeno
Colorectal Cancer
2004-03-01
CompletedA Study Evaluating Tarceva in Combination With Avastin Versus Avastin Alone in Treating Metastatic Renal Cell
Renal Cell Carcinoma, Metastases
Phase 22004-03-01
CompletedAn Observational Study of Treatment, Outcomes, and Prognosis in Patients With Follicular Non-Hodgkin's Lymphom
Lymphoma, Non Hodgkin
2004-03-01
CompletedA Study to Evaluate the Safety of Escalating Doses of Ocrelizumab in Subjects With Rheumatoid Arthritis
Rheumatoid Arthritis
Phase 1 / Phase 22004-02-01
CompletedA Study to Evaluate Efalizumab in Adults With Plaque Psoriasis, Including Those Who Are Receiving Concomitant
Psoriasis
Phase 32003-10-01
CompletedA Study to Evaluate Nutropin AQ for the Treatment of Growth Restriction in Children With Cystic Fibrosis
Cystic Fibrosis
Phase 22003-09-01
CompletedSafety Study of Oral Pirfenidone in Patients With Pulmonary Fibrosis/Idiopathic Pulmonary Fibrosis
Idiopathic Pulmonary Fibrosis, Pulmonary Fibrosis
Phase 22003-08-31
CompletedA Study Evaluating Topical Recombinant Human Vascular Endothelial Growth Factor (Telbermin) for Induction of H
Foot Ulcer
Phase 12003-08-01
CompletedA Study of the Safety and Efficacy of Tarceva in Patients With First Relapse of Grade IV Glioma (Glioblastoma
Glioblastoma
Phase 22003-07-01
CompletedSafety and Effect of Pertuzumab in Patients With Advanced Non-Small Cell Lung Cancer, Which Has Progressed Aft
Non-small Cell Lung Cancer
Phase 22003-07-01
CompletedStudy to Assess the Efficacy and Safety of Rituximab in Patients With Rheumatoid Arthritis
Rheumatoid Arthritis
Phase 22003-06-01
CompletedA Study to Evaluate the Effects of Efalizumab on Immune Responses in Subjects With Moderate Plaque Psoriasis
Plaque Psoriasis
Phase 12003-05-01
CompletedA Study to Compare rhuFab V2 With Verteporfin Photodynamic in Treating Subfoveal Neovascular Macular Degenerat
Macular Degeneration
Phase 32003-05-01
CompletedA Continued Access Protocol to Provide Xolair to Patients With Severe Allergic Asthma
Asthma
Phase 32003-05-01
CompletedA Study to Evaluate the Effect of HER2 Activation on rhuMAb 2C4 (Pertuzumab) in Subjects With Advanced Ovarian
Ovarian Cancer
Phase 22003-05-01
CompletedSafety and Efficacy Study of Pertuzumab to Treat Castration-Resistant Prostate Cancer
Prostate Cancer
Phase 22003-04-01
CompletedIntravitreal Injections of rhuFab V2 in Combination With Visudyne in Subjects With Age Related Macular Degener
Age-Related Maculopathy
Phase 1 / Phase 22003-03-01
CompletedA Study of Patients With HER2-Positive Metastatic Breast Cancer
Breast Cancer
2003-03-01
CompletedA Study to Evaluate rhuFab V2 in Subjects With Minimally Classic or Occult Subfoveal Neovascular Macular Degen
Macular Degeneration
Phase 32003-03-01
CompletedNational Cooperative Growth Study (NCGS) of Optimal Nutropin AQ and Nutropin Dosing in Pubertal Growth Hormone
Dwarfism, Pituitary
2003-02-01
CompletedA Study to Evaluate the Safety of Raptiva in Adults With Plaque Psoriasis Previously Enrolled in Study ACD2600
Psoriasis
Phase 32002-10-01
CompletedSafety, Efficacy, and Pharmacokinetics Study of Tarceva to Treat Advanced Colorectal Cancer
Colorectal Cancer
Phase 12002-10-01
CompletedA Study to Evaluate Avastin in Patients Treated in a Previous Genentech-Sponsored Cancer Study
Breast Cancer, Colorectal Cancer, Metastases
Phase 32002-10-01
CompletedExtension Study of rhuFab V2 in Subjects With Neovascular Age-Related Macular Degeneration (AMD)
Macular Degeneration
Phase 32002-09-01
CompletedA Study to Evaluate Raptiva in Adults With Moderate to Severe Plaque Psoriasis Who Are Candidates for Systemic
Psoriasis
Phase 32002-09-01
CompletedAn Extension Study of Xolair in Moderate to Severe, Persistent Asthma Patients Who Completed Study Q2143g
Asthma
Phase 32002-06-01
CompletedCathflo Activase Pediatric Study
Dysfunctional Central Venous Access Devices (CVADS)
Phase 42002-04-01
CompletedA Study in Children With Growth Failure Due to Chronic Renal Insufficiency (CRI) or End Stage Renal Disease (E
Chronic Renal Insufficiency, End-Stage Renal Disease
2002-03-01
CompletedA Study to Evaluate Raptiva in Adults With Plaque Psoriasis Previously Enrolled in Study ACD2390g
Psoriasis
Phase 32002-01-01
CompletedSafety Study of rhuMAb 2C4 to Treat Advanced Solid Tumors
Neoplasms
Phase 12001-11-01
CompletedA Study With Tarceva and Chemotherapy vs. Chemotherapy Alone in Patients With Advanced Lung Cancer
Lung Cancer
Phase 32001-07-01
CompletedA Study to Evaluate Erlotinib in Patients With Advanced or Metastatic Breast Cancer During or Following Chemot
Breast Cancer
Phase 22001-05-01
CompletedA Study to Evaluate Raptiva in Combination With Topical Psoriasis Therapies
Psoriasis
Phase 42001-02-01
CompletedA Study of Patients With HER2 Gene Amplified Metastatic Breast Cancer Treated With First Line Herceptin and a
Breast Cancer, Metastases
2000-11-30
CompletedA Study of rhuMAb VEGF (Bevacizumab) in Combination With Chemotherapy in Patients With Previously Treated Brea
Breast Cancer
Phase 32000-11-01
CompletedA Study to Evaluate Avastin in Combination With Standard Chemotherapy to Treat Colorectal Cancer
Colorectal Cancer
Phase 32000-09-01
CompletedAn Observational Study of TNKase in Patients Enrolled in the National Registry of Myocardial Infarction 4 and
Acute Myocardial Infarction
2000-09-01
CompletedA Study to Evaluate Avastin in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancer
Colorectal Cancer
Phase 22000-08-01
CompletedA Study to Evaluate the Safety of Xolair in Moderate to Severe Persistent Asthma Patients (ALTO)
Asthma
Phase 32000-07-01
CompletedBone Mineral Density (BMD) in Adolescents With Growth Hormone Deficiency (GHD)
Dwarfism, Pituitary, Turner Syndrome
2000-04-01
CompletedTrastuzumab Plus Paclitaxel in Treating Women With Metastatic Breast Cancer That Overexpresses HER2
Breast Cancer
Phase 22000-01-01
CompletedA Study to Determine the Variability of a 6-Minute Walk Test in Cystic Fibrosis Subjects With Advanced Lung Di
Cystic Fibrosis
1999-10-01
CompletedAn Extension Study to Evaluate Avastin in Patients Treated in a Previous Genentech-Sponsored Cancer Study
Cancer
Phase 21998-02-01
CompletedA Study to Evaluate Subjects With Turner Syndrome Treated With Growth Hormone
Turner Syndrome
1997-05-01
CompletedNational Cooperative Growth Study (NCGS): A Post-marketing Surveillance Program for Nutropin, Nutropin AQ, Nut
Growth Disorders
1985-10-01
CompletedA Phase I Study of the Safety and Pharmacokinetics of Recombinant CD4 (rCD4) in Patients With AIDS and AIDS-Re
HIV Infections
Phase 1
Approved For MarketingAn Expanded Access Program of Emicizumab in Participants With Hemophilia A With Inhibitors
Hemophilia A
Approved For MarketingAn Expanded Access Program for Risdiplam in Participants With Spinal Muscular Atrophy (SMA)
Muscular Atrophy, Spinal
CompletedA Phase I Study of Recombinant Human CD4 Immunoglobulin G (rCD4-lgG) in Patients With HIV-Associated Immune Th
Immune Thrombocytopenic Purpura ( ITP ), HIV Infections
Phase 1
Approved For MarketingExpanded Access Program (EAP): Allow Patients in the US With Idiopathic Pulmonary Fibrosis Access to Pirfenido
Idiopathic Pulmonary Fibrosis
WithdrawnEfficacy and Safety Study of rhuMAb VEGF to Treat Metastatic Renal Cell Carcinoma
Renal Cell Cancer
Phase 3
CompletedA Phase I Study of the Safety and Immunogenicity of Rgp 120/HIV-1IIIB Vaccine in HIV-1 Seropositive Adult Volu
HIV Infections
Phase 1
Approved For MarketingAn Expanded Access Study to Provide at Home Subcutaneous Administration of Pertuzumab and Trastuzumab Fixed-Do
HER2-positive Breast Cancer

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