Clinical Trials Directory

Trials / Completed

CompletedNCT01249131

A Study of Relative Bioavailability and Food Effect Study of Cobimetinib in Healthy Participants

A Phase I, Single-Dose, Randomized, Cross-Over, Relative Bioavailability, and Food Effect Study of GDC-0973 in Healthy Subjects

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
20 (actual)
Sponsor
Genentech, Inc. · Industry
Sex
All
Age
18 Years – 55 Years
Healthy volunteers
Accepted

Summary

This study will be an open-label, randomized, 3-way, 6-sequence crossover study in healthy participants for determining the relative bioavailability of the tablet formulation to the capsule formulation and the effect of food on the relative bioavailability of the tablet formulation.

Conditions

Interventions

TypeNameDescription
DRUGCobimetinibCobimetinib 20 mg will be given orally as tablet formulation in fasted or fed state, or as capsule formulation in fasted state.

Timeline

Start date
2010-12-01
Primary completion
2011-01-10
Completion
2011-01-10
First posted
2010-11-29
Last updated
2017-08-15
Results posted
2016-07-18

Source: ClinicalTrials.gov record NCT01249131. Inclusion in this directory is not an endorsement.