Trials / Completed
CompletedNCT01173536
A Study to Investigate the Effect of GDC-0449 on the QT/QTc Interval in Healthy Female Subjects
A Multiple-Dose, Randomized, Double-Blind, Placebo-Controlled, Active-Comparator, Parallel-Group Study to Investigate the Effect of GDC-0449 on the QT/QTc Interval in Healthy Female Subjects
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 61 (actual)
- Sponsor
- Genentech, Inc. · Industry
- Sex
- Female
- Age
- 45 Years
- Healthy volunteers
- Accepted
Summary
This is a Phase I, single-center, three-arm, randomized, double-blind, active- and placebo-controlled study to investigate the effect of GDC-0449 on the QT/QTc interval in healthy female subjects of non-childbearing potential.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | GDC-0449 | Oral repeating dose |
| DRUG | moxifloxacin | Oral single dose |
| DRUG | placebo | Oral repeating dose |
Timeline
- Start date
- 2010-08-25
- Primary completion
- 2011-03-18
- Completion
- 2011-03-18
- First posted
- 2010-08-02
- Last updated
- 2017-02-17
Source: ClinicalTrials.gov record NCT01173536. Inclusion in this directory is not an endorsement.