Clinical Trials Directory

Trials / Completed

CompletedNCT02284607

A Study of High Dose MHAA4549A in Healthy Volunteers

A PHASE I, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, SINGLE-ASCENDING DOSE STUDY TO INVESTIGATE THE SAFETY, TOLERABILITY, AND PHARMACOKINETICS OF HIGH DOSE MHAA4549A IN HEALTHY VOLUNTEERS

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
14 (actual)
Sponsor
Genentech, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Accepted

Summary

This Phase 1, randomized, double-blind, placebo-controlled study will evaluate the safety, tolerability and pharmacokinetics of two, single intravenous (IV) high doses of MHAA4549A as compared to placebo when administered to healthy volunteers.

Conditions

Interventions

TypeNameDescription
DRUGMHAA4549AMHAA4549A single, intravenous dose administration, lower dose level
DRUGMHAA4549AMHAA4549A single, intravenous dose administration, higher dose level
DRUGPlaceboMatching placebo to MHAA4549A administration

Timeline

Start date
2014-11-03
Primary completion
2015-03-13
Completion
2015-03-13
First posted
2014-11-06
Last updated
2017-03-09

Locations

1 site across 1 country: Canada

Source: ClinicalTrials.gov record NCT02284607. Inclusion in this directory is not an endorsement.