Clinical Trials Directory

Trials / Completed

CompletedNCT00337883

A Study of the Safety and Efficacy of Tarceva in Patients With First Relapse of Grade IV Glioma (Glioblastoma Multiforme)

A Phase II, Multicenter, Open-Label Trial of the Safety and Efficacy of Tarceva (Erlotinib Hydrochloride) in Patients With First Relapse of Grade IV Glioma (Glioblastoma Multiforme)

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
110 (planned)
Sponsor
Genentech, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a Phase II, open-label, multicenter trial of single-agent treatment with Tarceva in patients with histologically confirmed GBM in first relapse. This study seeks to estimate the objective response rate and will investigate whether response rate is related to EGFR amplification status.

Conditions

Interventions

TypeNameDescription
DRUGErlotinib HCl (OSI-774)

Timeline

Start date
2003-07-01
Completion
2005-10-01
First posted
2006-06-20
Last updated
2014-03-04

Source: ClinicalTrials.gov record NCT00337883. Inclusion in this directory is not an endorsement.

A Study of the Safety and Efficacy of Tarceva in Patients With First Relapse of Grade IV Glioma (Glioblastoma Multiforme (NCT00337883) · Clinical Trials Directory