Clinical Trials Directory

Trials / Completed

CompletedNCT01442090

Study of GDC-0980 Versus Everolimus in Participants With Metastatic Renal Cell Carcinoma Who Have Progressed on or Following Vascular Endothelial Growth Factor- (VEGF) Targeted Therapy

A Phase II, Open-Label, Randomized Study of GDC-0980 Versus Everolimus in Patients With Metastatic Renal Cell Carcinoma Who Have Progressed on or Following VEGF-Targeted Therapy

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
85 (actual)
Sponsor
Genentech, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Study PIM4973g is a multicenter, international, open-label Phase II trial. Participants with metastatic renal cell carcinoma who have progressed on or after VEGF targeted therapy will be randomized in 1:1 to two groups either to receive daily GDC-0980 or everolimus orally.

Conditions

Interventions

TypeNameDescription
DRUGEverolimusEverolimus will be administered orally at a 10 mg daily dose.
DRUGGDC-0980GDC-0980 will be administered orally at a 40 mg daily dose.

Timeline

Start date
2011-10-01
Primary completion
2013-05-01
Completion
2015-07-01
First posted
2011-09-28
Last updated
2016-08-10

Locations

22 sites across 5 countries: United States, France, Germany, Spain, United Kingdom

Source: ClinicalTrials.gov record NCT01442090. Inclusion in this directory is not an endorsement.