Trials / Completed
CompletedNCT01090960
A Study Evaluating the Safety and Tolerability of GDC-0068 in Patients With Refractory Solid Tumors
An Open-Label, Phase I, Dose-Escalation Study Evaluating the Safety and Tolerability of GDC-0068 in Patients With Refractory Solid Tumors
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 52 (actual)
- Sponsor
- Genentech, Inc. · Industry
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This is an open-label, multicenter, Phase I study to evaluate the safety, tolerability, and pharmacokinetics of escalating oral doses of GDC-0068 administered to patients with incurable, locally advanced or metastatic solid malignancy that has progressed or failed to respond to at least one prior regimen or for which there is no standard therapy. This study is expected to enroll approximately 39 to 57 patients at approximately two sites in Spain.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | GDC-0068 | Oral repeating dose |
Timeline
- Start date
- 2010-03-01
- Primary completion
- 2015-02-01
- Completion
- 2015-02-01
- First posted
- 2010-03-23
- Last updated
- 2016-07-04
Locations
2 sites across 1 country: Spain
Source: ClinicalTrials.gov record NCT01090960. Inclusion in this directory is not an endorsement.