| Recruiting | China Post-approval Commitment (PAC) Study of Avalglucosidase Alfa in Participants With IOPD Glycogen Storage Disease Type II, Pompe's Disease | Phase 4 | 2025-05-07 |
| Active Not Recruiting | Avalglucosidase Alfa French Post-trial Access for Participants With Pompe Disease (PTA Avalglucosidase) Glycogen Storage Disease Type II | Phase 4 | 2022-07-11 |
| Completed | China Post-marketing Surveillance (PMS) Study of Aldurazyme® Mucopolysaccharidosis I | Phase 4 | 2021-10-28 |
| Completed | China Post-marketing Surveillance (PMS) Study of Fabrazyme® Fabry Disease | Phase 4 | 2021-10-13 |
| Completed | Study to Evaluate Efficacy and Safety in Chinese Patients With Late Onset Pompe Disease With Alglucosidase Alf Pompe's Disease | Phase 4 | 2021-03-10 |
| Terminated | A Multinational, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy, Pharmacodynamics, Tay-Sachs Disease, Sandhoff Disease | Phase 3 | 2020-06-29 |
| Completed | Excretion Balance, Pharmacokinetics, and Metabolism Following of [14C]-Venglustat Administration in Healthy Ma Disorders of Sphingolipid Metabolism, Healthy Volunteers | Phase 1 | 2020-05-26 |
| Active Not Recruiting | Fitusiran Prophylaxis in Male Pediatric Subjects Aged 1 to Less Than 12 Years With Hemophilia A or B Hemophilia | Phase 3 | 2020-01-28 |
| Terminated | Study of Lademirsen (SAR339375) in Patients With Alport Syndrome Alport Syndrome | Phase 2 | 2019-11-02 |
| Completed | Collection of Blood Samples From Patients With Relapsing MS Who Developed ITP After Receiving Lemtrada Multiple Sclerosis | Phase 4 | 2019-02-08 |
| Active Not Recruiting | Long-term Safety and Efficacy Study of Fitusiran in Patients With Hemophilia A or B, With or Without Inhibitor Hemophilia | Phase 3 | 2019-01-09 |
| Completed | Evaluate Efficacy and Safety in Chinese Patients With Infantile-Onset Pompe Disease With One Year Alglucosidas Glycogen Storage Disease Type II | Phase 4 | 2018-12-04 |
| Completed | Effect of Venglustat in Patients With Renal Impairment Healthy Volunteers, Polycystic Kidney, Autosomal Dominant | Phase 1 | 2018-10-05 |
| Terminated | A Medical Research Study Designed to Determine if Venglustat Can be a Future Treatment for ADPKD Patients Polycystic Kidney, Autosomal Dominant | Phase 2 / Phase 3 | 2018-10-04 |
| Completed | A Study of the Safety, Tolerability, and Pharmacokinetics of Orally Administered Venglustat and Itraconazole i Healthy Volunteers | Phase 1 | 2018-08-16 |
| Completed | A Study of Fitusiran in Severe Hemophilia A and B Patients Previously Receiving Factor or Bypassing Agent Prop Hemophilia | Phase 3 | 2018-07-25 |
| Completed | A Study of Fitusiran (ALN-AT3SC) in Severe Hemophilia A and B Patients Without Inhibitors Hemophilia A, Hemophilia B | Phase 3 | 2018-03-01 |
| Completed | A Study of Fitusiran (ALN-AT3SC) in Severe Hemophilia A and B Patients With Inhibitors Hemophilia A, Hemophilia B | Phase 3 | 2018-02-14 |
| Completed | A Study of RG-012 in Subjects With Alport Syndrome Alport Syndrome | Phase 1 | 2017-12-22 |
| Terminated | A Study to Evaluate Efficacy, Safety, and Tolerability of Alemtuzumab in Pediatric Patients With RRMS With Dis Multiple Sclerosis | Phase 3 | 2017-10-24 |
| Active Not Recruiting | A Study to Assess Safety and Efficacy of Avalglucosidase Alfa Administered Every Other Week in Pediatric Patie Glycogen Storage Disease Type II-Pompe's Disease | Phase 2 | 2017-10-12 |
| Completed | Randomized Study of the Efficacy and Safety of a Single Dose of Synvisc-One® in Chinese Patients With Symptoma Osteoarthritis | Phase 3 | 2017-08-21 |
| Active Not Recruiting | Venglustat in Combination With Cerezyme in Adult Patients With Gaucher Disease Type 3 With Venglustat Monother Gaucher Disease Type 1, Gaucher Disease Type 3 | Phase 2 | 2017-01-04 |
| Terminated | A Global Study to Assess the Drug Dynamics, Efficacy, and Safety of Venglustat (GZ/SAR402671) in Parkinson's D Parkinson's Disease | Phase 2 | 2016-12-15 |
| Completed | Study to Compare the Efficacy and Safety of Enzyme Replacement Therapies Avalglucosidase Alfa and Alglucosidas Glycogen Storage Disease Type II;Pompe's Disease | Phase 3 | 2016-11-02 |
| Completed | Proof-of-concept Study to Assess the Efficacy, Tolerability and Safety of a Single Intraarticular Dose of GZ38 Osteoarthritis | Phase 2 | 2016-07-21 |
| Completed | Efficacy, Safety, Pharmacodynamic, and Pharmacokinetics Study of Olipudase Alfa in Patients With Acid Sphingom Sphingomyelin Lipidosis | Phase 2 / Phase 3 | 2015-12-18 |
| Completed | A Study to Characterize Subcutaneous or Intravenous Alemtuzumab in Patients With Progressive Multiple Sclerosi Progressive Multiple Sclerosis | Phase 1 | 2015-12-06 |
| Completed | Phase 3b Study to Evaluate Skeletal Response to Eliglustat in Adult Patients Who Completed Phase 2 or Phase 3 Gaucher Disease | Phase 3 | 2015-10-27 |
| Completed | An Open-label Extension Study of an Investigational Drug, Fitusiran, in Patients With Moderate or Severe Hemop Hemophilia A, Hemophilia B | Phase 1 / Phase 2 | 2015-09-18 |
| Terminated | LEMTRADA Pregnancy Registry in Multiple Sclerosis Multiple Sclerosis | — | 2015-09-01 |
| Completed | A Study of the Effects of Hepatic Impairment on the Pharmacokinetics and Tolerability of Eliglustat Tartrate Gaucher Disease | Phase 1 | 2015-09-01 |
| Completed | Evaluation of the Long-term Safety, Pharmacodynamics, and Exploratory Efficacy of GZ/SAR402671 in Treatment-Na Fabry Disease | Phase 2 | 2015-07-07 |
| Completed | Safety, Tolerability, PK, and Efficacy Evaluation of Repeat Ascending Doses of Olipudase Alfa in Pediatric Pat Sphingomyelin Lipidosis | Phase 1 / Phase 2 | 2015-05-01 |
| Completed | First-in-human Study With Ascending Single Intra-articular Doses of GZ389988 in Patients With Painful Osteoart Osteoarthritis | Phase 1 | 2015-04-01 |
| Completed | Taste Evaluation of Different Liquid Formulations With Eliglustat Gaucher Disease | Phase 1 | 2015-04-01 |
| Completed | Alglucosidase Alfa Pompe Safety Sub-Registry Pompe Disease | — | 2015-03-20 |
| Terminated | Efficacy and Safety of Vatelizumab in Patients Who Completed Treatment in Study DRI13839 Relapsing-remitting Multiple Sclerosis | Phase 2 | 2015-02-01 |
| Completed | A Long-term Follow-up Study Of Multiple Sclerosis Patients Who Participated In Genzyme-sponsored Studies of GZ Progressive Multiple Sclerosis | — | 2015-01-12 |
| Completed | Phase IIIB-IV Long-Term Follow-up Study for Patients Who Participated in CAMMS03409 Relapsing Remitting Multiple Sclerosis | Phase 4 | 2015-01-07 |
| Completed | Pharmacokinetics of Alglucosidase Alfa in Patients With Pompe Disease Pompe Disease, Glycogen Storage Disease Type II (GSD II) | Phase 4 | 2014-11-03 |
| Completed | Plerixafor Plus Granulocyte Colony-Stimulating Factor For Mobilization And Collection Of Peripheral Hematopoie Lymphoma | Phase 2 | 2014-11-01 |
| Completed | Evaluate the Safety, Pharmacodynamics, Pharmacokinetics, and Exploratory Efficacy of GZ/SAR402671 in Treatment Fabry Disease | Phase 2 | 2014-11-01 |
| Completed | A First-in-human, Single Ascending Dose Study of GZ402668 in Patients With Progressive Multiple Sclerosis Progressive Multiple Sclerosis | Phase 1 | 2014-10-01 |
| Completed | Management Of The Infusion-Associated Reactions In RRMS Patients Treated With LEMTRADA Relapsing-remitting Multiple Sclerosis | Phase 4 | 2014-10-01 |
| Completed | Plerixafor Plus Granulocyte Colony-stimulating Factor (G-CSF) For Mobilization And Collection Of Peripheral He Multiple Myeloma | Phase 2 | 2014-10-01 |
| Completed | ATHENA: Natural History of Disease Study in Alport Syndrome Patients Alport Syndrome Patients With eGFR Between 45-90 ml/Min/1.73 m2 | — | 2014-09-04 |
| Terminated | Efficacy and Safety of Vatelizumab in Patients With Relapsing-Remitting Multiple Sclerosis Relapsing-remitting Multiple Sclerosis | Phase 2 | 2014-09-01 |
| Completed | Efficacy, Safety and Pharmacokinetics of Teriflunomide in Pediatric Patients With Relapsing Forms of Multiple Multiple Sclerosis | Phase 3 | 2014-07-16 |
| Completed | CAPRELSA® REGISTRY: a Belgian Registry to Evaluate the Use of Vandetanib (Caprelsa®) in Current Clinical Pract Metastatic Medullary Thyroid Cancer | — | 2014-04-01 |
| Completed | A Combined Study in Pediatric Cancer Patients for Dose Ranging and Efficacy/Safety of Plerixafor Plus Standard Ewing's Sarcoma/Soft Tissue Sarcoma, Neuroblastoma, Brain Tumors | Phase 1 / Phase 2 | 2014-03-03 |
| Completed | Avalglucosidase Alfa Extension Study Glycogen Storage Disease Type II Pompe Disease | Phase 2 | 2014-02-27 |
| Completed | Observational Study to Evaluate Vandetanib in RET -/+ Patients With Metastatic Medullary Thyroid Cancer Symptomatic, Aggressive, Sporadic, Unresectable, Locally, Advanced/Metastatic Medullary Thyroid Cancer (MTC) | — | 2014-02-17 |
| Completed | A Long-Term Study of Olipudase Alfa in Patients With Acid Sphingomyelinase Deficiency Sphingomyelin Lipidosis | Phase 2 | 2013-12-04 |
| Completed | An Open Label, Dose Titration Study of Sevelamer Carbonate Tablets & Powder in Hyperphosphatemic CKD Patients Renal Failure Chronic | Phase 3 | 2013-10-01 |
| Completed | Evaluation of Efficacy, Safety of Vandetanib in Patients With Differentiated Thyroid Cancer Differentiated Thyroid Cancer | Phase 3 | 2013-09-17 |
| Completed | Safety and Efficacy Evaluation of Repeat neoGAA Dosing in Late Onset Pompe Disease Patients. Pompe Disease, Glycogen Storage Disease Type II (GSD II), Acid Maltase Deficiency | Phase 1 | 2013-08-19 |
| Terminated | A Study of Renal Function in Treatment-naïve, Young Male Patients With Fabry Disease Fabry Disease | Phase 1 | 2013-05-01 |
| Completed | Tolerability and Safety Study of Recombinant Human Acid Sphingomyelinase in Acid Sphingomyelinase Deficiency P Human Acid Sphingomyelinase Deficiency | Phase 1 | 2013-03-01 |
| Completed | Evaluate the Safety and Tolerability of Vandetanib in Japanese Patients With Medullary Thyroid Carcinoma Unresectable Locally Advanced or Metastatic, Medullary Thyroid Carcinoma | Phase 1 / Phase 2 | 2012-11-01 |
| Completed | A Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study of Genz-682452 in Healthy Volunteers Healthy | Phase 1 | 2012-10-01 |
| Completed | A Study of the Safety and Effectiveness of Synvisc-One® (Hylan G-F 20) in Patients With Primary Osteoarthritis Osteoarthritis, Hip | N/A | 2012-09-01 |
| Completed | Safety, Tolerability and Pharmacokinetics of Genz-682452 in Healthy Men Healthy Volunteer | Phase 1 | 2012-08-01 |
| Terminated | A Noninferiority Study of Alglucosidase Alfa Manufactured at the 160 L and 4000 L Scales in Treatment Naïve Pa Pompe Disease (Infantile-Onset), Glycogen Storage Disease Type II (GSD II), Glycogenosis 2 | Phase 4 | 2012-08-01 |
| Completed | A Study of Fresolimumab in Patients With Steroid-Resistant Primary Focal Segmental Glomerulosclerosis (FSGS) Primary Focal Segmental Glomerulosclerosis | Phase 2 | 2012-08-01 |
| Completed | Vandetanib Risk Minimisation Effectiveness Medullary Thyroid Cancer | — | 2012-06-01 |
| Completed | Study to Evaluate the Effect of Eliglustat on the Pharmacokinetics, Safety and Tolerability of Metoprolol in H Healthy | Phase 1 | 2012-05-01 |
| Completed | An Efficacy and Safety Study of Sevelamer Carbonate in Hyperphosphatemic Pediatric Participants With Chronic K Hyperphosphatemia, Chronic Kidney Disease | Phase 2 | 2012-05-01 |
| Completed | A Retrospective Observational Study Comparing Two Different Treatment Options in Thyroid Cancer Patients With Thyroid Cancer | — | 2012-05-01 |
| Completed | A Study Evaluating Glycosphingolipid Clearance in Patients Treated With Agalsidase Alfa Who Switch to Agalsida Fabry Disease | Phase 4 | 2012-04-01 |
| Completed | Pompe Lactation Sub-Registry Glycogen Storage Disease, Pompe Disease | — | 2012-03-31 |
| Terminated | A Study to Evaluate the Efficacy and Safety of Alglucosidase Alfa Produced at the 4000 L Scale for Pompe Disea Pompe Disease | Phase 4 | 2012-03-01 |
| Completed | Registry of Patients Treated With Plerixafor (Mozobil®) for Haematopoietic Stem Cell Mobilization Before Autol Bone Marrow / Autologous Transplants | — | 2011-12-01 |
| Completed | A Phase I Study of the Pharmacokinetic Variability and Relative Bioavailability of the Phase 3 and Common Blen Healthy Volunteer | Phase 1 | 2011-10-01 |
| Completed | A Phase I Dose Escalation Study of Plerixafor in Healthy Subjects of Japanese Descent Healthy Volunteer | Phase 1 | 2011-09-01 |
| Completed | A Phase 1 Study Evaluating Eliglustat's Effects on Pharmacokinetics, Safety & Tolerability of Digoxin in Healt Healthy Volunteer | Phase 1 | 2011-08-01 |
| Completed | Exploratory Muscle Biopsy Assessment Study in Patients With Late-Onset Pompe Disease Treated With Alglucosidas Pompe Disease (Late-Onset), Glycogen Storage Disease Type II (GSD II), Glycogenesis 2 Acid Maltase Deficiency | Phase 4 | 2011-06-01 |
| Completed | Analysis of Data Collected in the European Group for Blood and Marrow Transplantation (EBMT) Registry on a Coh Lymphoma, Multiple Myeloma | — | 2011-03-01 |
| Terminated | A Study of the Effect of Aldurazyme® (Laronidase) Treatment on Lactation in Female Patients With Mucopolysacch Mucopolysaccharidosis I, Hurler's Syndrome, Hurler-Scheie Syndrome | Phase 4 | 2010-10-22 |
| Completed | Evaluation of Approved Weight-Based Dose Compared to Fixed Dose of Plerixafor in Patients With Non-Hodgkin's L Non-Hodgkin's Lymphoma | Phase 4 | 2010-10-01 |
| Completed | Post Authorisation Safety Study of Renvela® in Chronic Kidney Disease Patients Not on Dialysis With Hyperphosp Hyperphosphataemia, Chronic Kidney Disease | — | 2010-09-01 |
| Completed | A Study of Clofarabine in Japanese Paediatric Patients With Relapsed or Refractory Acute Lymphoblastic Leukaem Acute Lymphoblastic Leukemia | Phase 1 | 2010-08-01 |
| Completed | A Study of Eliglustat Tartrate (Genz-112638) in Patients With Gaucher Disease to Evaluate Once Daily Versus Tw Gaucher Disease | Phase 3 | 2010-06-01 |
| Completed | Dose-Titration Study of Sevelamer Carbonate in Chronic Kidney Disease (CKD) Patients on Hemodialysis Chronic Kidney Disease, Chronic Kidney Disease on Hemodialysis | Phase 3 | 2010-03-01 |
| Completed | A Study of Clofarabine in Japanese Patients With Acute Myeloid Leukemia (AML) Acute Myelogenous Leukemia | Phase 1 | 2010-02-01 |
| Completed | Study of Safety and Efficacy of 6 mL Synvisc-One (Hylan G-F 20) in Indian Patients With Symptomatic Osteoarthr Osteoarthritis | Phase 4 | 2010-02-01 |
| Completed | A Safety Confirmatory Study of Alemtuzumab in Japanese Patients With Relapsed or Refractory Chronic Lymphocyti Leukemia, Lymphocytic, Chronic, B-Cell | Phase 1 | 2010-02-01 |
| Completed | Safety and Tolerability Study of AAV2-sFLT01 in Patients With Neovascular Age-Related Macular Degeneration (AM Macular Degeneration, Age-Related Maculopathies, Age-Related Maculopathy | Phase 1 | 2010-01-11 |
| Completed | Study of Plerixafor Combined With Cytarabine and Daunorubicin in Patients With Newly Diagnosed Acute Myeloid L Acute Myeloid Leukemia | Phase 1 | 2009-12-01 |
| Completed | A Study of Eliglustat Tartrate (Genz-112638) in Patients With Gaucher Disease (ENGAGE) Gaucher Disease, Type 1 | Phase 3 | 2009-11-01 |
| Completed | A Safety and Tolerability Study of Clofarabine, Etoposide, Cyclophosphamide, PEG-asparaginase, and Vincristine Lymphoblastic Leukemia, Acute, Childhood | Phase 1 | 2009-10-01 |
| Completed | An Exploratory Study of the Safety and Efficacy of Prophylactic Immunomodulatory Treatment in Myozyme-naive Cr Pompe Disease, Glycogen Storage Disease Type II | Phase 4 | 2009-10-01 |
| Completed | A Study of Eliglustat Tartrate (Genz-112638) in Patients With Gaucher Disease Who Have Reached Therapeutic Goa Gaucher Disease, Type 1 | Phase 3 | 2009-09-01 |
| Completed | An Extension Protocol for Multiple Sclerosis Patients Who Participated in Genzyme-Sponsored Studies of Alemtuz Multiple Sclerosis, Relapsing-Remitting | Phase 3 | 2009-08-01 |
| Completed | Dose Escalation Study to Assess the Safety and Tolerability of Genz-644282 in Patients With Solid Tumors Solid Tumors | Phase 1 | 2009-07-01 |
| Completed | Analysis of Data Collected in the European Group for Blood and Marrow Transplantation (EBMT) Registry for Off- Acute Leukemia, Chronic Leukemia, Myelodysplastic Syndrome | — | 2009-07-01 |
| Terminated | Addition of Vandetanib to Standard Therapy Pegliposomal Doxorubicin (PLD) Ovarian Cancer | Phase 1 / Phase 2 | 2009-04-01 |
| Completed | Randomized Study Comparing Genz-644470, Placebo, and Sevelamer Carbonate in Chronic Kidney Disease Patients on Kidney Failure, Chronic | Phase 2 | 2009-02-01 |
| Terminated | A Randomised, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of Sevelamer Carbo Chronic Kidney Disease, Hyperphosphatemia | Phase 3 | 2009-01-01 |
| Terminated | Immune Tolerance Induction Study Pompe Disease, Glycogen Storage Disease Type II (GSD-II), Glycogenesis 2 Acid Maltase Deficiency | Phase 4 | 2008-12-14 |
| Terminated | ZACtima FASlodex Trial in Postmenopausal Advance Breast Cancer Patients Instead of ZACtima FASlodex Trial Breast Cancer | Phase 2 | 2008-12-01 |
| Withdrawn | A Screening Study Evaluating Disease Status of Gaucher Type I Patients Gaucher Disease, Type 1 | — | 2008-12-01 |
| Terminated | Evaluation of the Safety of Sepraspray in Open Abdominal Surgery Adhesion Prevention (Abdominal) | N/A | 2008-10-01 |
| Completed | Zactima in Non Small Cell Lung Cancer (NSCLC) ELderly Patients In Combination With or Versus Gemcitabine Non Small Cell Lung Cancer | Phase 2 | 2008-10-01 |
| Terminated | Safety, Effectiveness and Patient Acceptance of the Treatment With MabCampath in Chronic Lymphocytic Leukemia Chronic Lymphocytic Leukemia | — | 2008-10-01 |
| Completed | Phase II of Zactima Maintenance for Locally Advanced or Metastatic Non-small-cell Lung Carcinoma (NSCLC) Follo NSCLC | Phase 2 | 2008-10-01 |
| Completed | Vandetanib Gemcitabine Or Placebo Plus Gemcitabine Or Vandetanib Monotherapy In Advanced Biliary Tract Cancer Biliary Tract Cancer, Gallbladder Cancer, Cancer Of The Extrahepatic Bile Duct | Phase 2 | 2008-10-01 |
| Completed | A Multi-centre, Open Label, Single-arm Study Intended to Further Investigate the Safety and Efficacy of Plerix Lymphoma (Non-Hodgkin's Lymphoma), Hodgkin's Disease or Multiple Myeloma, Front Line Mobilization | Phase 3 | 2008-09-01 |
| Completed | Manageability and Safety Assessment of Sepraspray in Abdominal Surgery. Adhesion Prevention | N/A | 2008-09-01 |
| Terminated | A Study of Oral Clofarabine in Adult Patients With Myelodysplastic Syndromes (MDS) Myelodysplastic Syndromes | Phase 1 | 2008-09-01 |
| Completed | A Study of Two Fabrazyme (Agalsidase Beta) Dosing Regimens in Treatment-naïve, Male Pediatric Patients Without Fabry Disease | Phase 3 | 2008-09-01 |
| Completed | Immune Tolerance Study With Aldurazyme® (Laronidase) Mucopolysaccharidosis I | Phase 1 / Phase 2 | 2008-09-01 |
| Completed | Growth and Development Study of Alglucosidase Alfa Pompe Disease, Glycogen Storage Disease Type II (GSD-II), Acid Maltase Deficiency Disease | Phase 4 | 2008-08-26 |
| Completed | Study of AMD3100 (Plerixafor) and Rituximab in Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL) | Phase 1 | 2008-06-01 |
| Terminated | Trial Assessing Zactima Against Placebo in Prostate Cancer Subjects Undergoing Intermittent Androgen Deprivati Prostate Cancer | Phase 2 | 2008-05-01 |
| Completed | A Study to Evaluate the Safety and Effectiveness of Doxercalciferol Capsules in Participants With Moderate to Moderate to Severe Chronic Plaque Psoriasis | Phase 2 | 2008-04-01 |
| Completed | A Multicenter, Active and Placebo-controlled Study of Enteric Coated Sevelamer in Patients With Mild to Modera Hypercholesterolemia | Phase 2 | 2008-02-01 |
| Completed | Efficacy and Safety of Zactima™ in Patients With Castration-refractory Metastatic Prostate Cancer Prostate Cancer | Phase 2 | 2008-02-01 |
| Terminated | An Efficacy and Safety Study With Vandetanib to Treat Inoperable or Relapsed Malignant Mesothelioma Mesothelioma | Phase 2 | 2007-12-01 |
| Completed | Sepraspray™ Laparoscopic Myomectomy Study Laparoscopic Myomectomy | N/A | 2007-11-01 |
| Completed | Evaluation of the Safety and Efficacy of the Addition of AMD3100 to a G-CSF Mobilization Regimen in Patients W Lymphoma, Non Hodgkin's Lymphoma, Hodgkin's Disease | Phase 2 | 2007-11-01 |
| Terminated | Rabbit Anti-thymocyte Globulin in the Treatment of Patients With Low to Intermediate-1 Risk Myelodysplastic Sy Myelodysplastic Syndrome (MDS) | Phase 2 | 2007-10-01 |
| Completed | Comparison of Alemtuzumab and Rebif® Efficacy in Multiple Sclerosis, Study Two Multiple Sclerosis, Relapsing-Remitting | Phase 3 | 2007-10-01 |
| Completed | Efficacy and Safety of Vandetanib (ZD6474) in Patients With Metastatic Papillary or Follicular Thyroid Cancer Thyroid Neoplasms | Phase 2 | 2007-09-28 |
| Completed | A Study to Assess Any Potential Interaction Between Colesevelam and Ciclosporin in Healthy Volunteers Healthy | Phase 1 | 2007-09-01 |
| Completed | A Study of the Safety and Efficacy of Patients With Familial Hypercholesterolaemia Taking Colesevelam as add-o Familial Hypercholesterolemia | Phase 4 | 2007-08-01 |
| Completed | Comparison of Alemtuzumab and Rebif® Efficacy in Multiple Sclerosis, Study One Multiple Sclerosis, Relapsing-Remitting | Phase 3 | 2007-08-01 |
| Completed | Study to Determine the Dose, the Safety and Effectiveness of a New Drug, Modified Release rhTSH, in Patients W Multinodular Goiter | Phase 2 | 2007-07-01 |
| Terminated | Evaluation of the Safety and Effectiveness of Sepraspray™ in Reducing Post-surgical Adhesions Abdominal Adhesions | N/A | 2007-07-01 |
| Completed | Phase II Study of Best Support Care (BSC) Plus ZD6474(Vandetanib) in Patients With Inoperable Hepatocellular C Carcinoma, Hepatocellular | Phase 2 | 2007-07-01 |
| Recruiting | Pompe Pregnancy Sub-Registry Glycogen Storage Disease Type II (GSD-II), Pompe Disease (Late-onset), Glycogenesis 2 Acid Maltase Deficiency | — | 2007-06-18 |
| Completed | A Dose Confirmation Study of Oral Clofarabine for Adult Patients Previously Treated for Myelodysplastic Syndro Myelodysplastic Syndromes, Secondary Acute Myeloid Leukemia (AML) | Phase 2 | 2007-05-07 |
| Completed | High Dose or High Dose Frequency Study of Alglucosidase Alfa Pompe Disease, Glycogen Storage Disease Type II (GSD-II), Glycogenesis 2 Acid Maltase Deficiency | Phase 4 | 2007-05-01 |
| Completed | Safety Study of GC1008 in Patients With Focal Segmental Glomerulosclerosis (FSGS) of Single Doses of GC1008 in Focal Segmental Glomerulosclerosis | Phase 1 | 2007-05-01 |
| Completed | A Study to Compare the Safety and Effectiveness of a Non-FDA Approved Device Dermal Gel Extra (DGE) and an FDA Facial Wrinkles at the Nasolabial Folds | Phase 3 | 2007-05-01 |
| Completed | A Phase 4 Study to Determine Dosing of Hectorol® Capsules When Converting From Zemplar® Injection Secondary Hyperparathyroidism | Phase 4 | 2007-04-01 |
| Terminated | A Study to Assess the Safety, Tolerability, Effectiveness and Absorption of Exodif™ Tablets in Clostridium Dif Enterocolitis, Pseudomembranous, Diarrhea, Clostridium Difficile | Phase 3 | 2007-04-01 |
| Completed | Study About the Evolution of Severe Late Onset Pompe Disease Patient With Pulmonary Dysfunction and Receiving Pompe Disease (Late-Onset), Glycogen Storage Disease Type II (GSD II), Glycogenesis 2 Acid Maltase Deficiency | — | 2007-03-01 |
| Completed | Late-Onset Treatment Study Extension Protocol Pompe Disease (Late-Onset), Glycogen Storage Disease Type II (GSD-II), Glycogenesis Type II | Phase 4 | 2007-03-01 |
| Completed | A Phase II Study of 2 Doses of ZD6474 (Vandetanib) in Combination With FOLFOX vs FOLFOX Alone for the Treatmen Colorectal, Cancer | Phase 2 | 2007-03-01 |
| Completed | A Phase II, Double Blind Study of 2 Doses of ZACTIMA™(ZD6474) in Combination With FOLFIRI vs FOLFIRI Alone for Colorectal Cancer | Phase 2 | 2007-03-01 |
| Completed | A Phase 4 Pharmacokinetic Study of Hectorol Injection and Zemplar Injection in CKD Subjects on Hemodialysis Secondary Hyperparathyroidism | Phase 4 | 2007-02-01 |
| Completed | A Study to Compare Subject Comfort During and After Injections With the Study Products and the Safety of the N Facial Wrinkles | Phase 3 | 2007-01-01 |
| Completed | Efficacy Study Comparing ZD6474 in Combination With Pemetrexed and Pemetrexed Alone in 2nd Line NSCLC Patients Non Small Cell Lung Cancer, Lung Cancer | Phase 3 | 2007-01-01 |
| Terminated | Safety Study of rhASM Enzyme Replacement Therapy in Adults With Acid Sphingomyelinase Deficiency (Niemann-Pick Acid Sphingomyelinase Deficiency, Niemann-Pick Disease | Phase 1 | 2006-12-01 |
| Completed | An Efficacy Study Comparing ZD6474 to Placebo in Medullary Thyroid Cancer Thyroid Cancer | Phase 3 | 2006-11-23 |
| Completed | ZD6474 (ZACTIMA™) Phase III Study in EGFR Failures Non-Small-Cell Lung Carcinoma | Phase 3 | 2006-11-01 |
| Completed | A Phase 4, Conversion Study of Hectorol® Injection to Hectorol® Capsules in Stage 5 CKD Patients on Dialysis Secondary Hyperparathyroidism | Phase 4 | 2006-11-01 |
| Completed | A Study of Clofarabine for Older Patients With Newly Diagnosed Acute Myelogenous Leukemia (AML) (CLASSIC II) Acute Myelogenous Leukemia, Acute Myeloid Leukemia | Phase 2 | 2006-10-01 |
| Completed | A Study of the Absorption of GT267-004 in Patients With Clostridium Difficile-Associated Diarrhea Pseudomembranous Colitis, Clostridium Difficile Diarrhea, Antibiotic-Associated Diarrhea | Phase 2 | 2006-09-01 |
| Completed | Phase I Chinese PK Advanced Solid, Malignant Tumors | Phase 1 | 2006-09-01 |
| Completed | Safety and Efficacy Study of GC1008 to Treat Renal Cell Carcinoma or Malignant Melanoma Carcinoma, Renal Cell, Melanoma | Phase 1 | 2006-09-01 |
| Completed | Efficacy Trial Comparing ZD6474 With Erlotinib in NSCLC After Failure of at Least One Prior Chemotherapy Non Small Cell Lung Cancer | Phase 3 | 2006-08-01 |
| Completed | A Study To Assess ZD6474 (ZACTIMA™) Monotherapy In Locally Advanced or Metastatic Hereditary Medullary Thyroid Thyroid Cancer | Phase 2 | 2006-08-01 |
| Completed | Phase I Combination With Vinorelbine or Gemcitabine Plus Cisplatin in Locally Advanced or Metastatic NSCLC Non Small Cell Lung Cancer | Phase 1 | 2006-08-01 |
| Completed | Phase I Efficacy On Vascular Permeability In Patients With Advanced Colorectal Cancer Colorectal Cancer | Phase 1 | 2006-08-01 |
| Completed | A Study of Clofarabine and Cytarabine for Older Patients With Relapsed or Refractory Acute Myelogenous Leukemi Acute Myelogenous Leukemia | Phase 3 | 2006-08-01 |
| Completed | Long-Term Follow-up Study for Non-Hodgkin's Lymphoma Patients Who Received Study Treatment (Plerixafor or Plac Non-Hodgkin's Lymphoma, Autologous Transplantation | — | 2006-06-01 |
| Terminated | Study of Sargramostim in Moderately to Severely Active Crohn's Disease Crohn's Disease | Phase 2 | 2006-06-01 |
| Completed | A Study of the Efficacy and Safety of Eliglustat Tartrate (Genz-112638) in Type 1 Gaucher Patients Gaucher Disease, Type 1, Cerebroside Lipidosis Syndrome, Glucocerebrosidase Deficiency Disease | Phase 2 | 2006-06-01 |
| Completed | Long-Term Follow-up Study for Multiple Myeloma Patients Who Received Study Treatment (Plerixafor or Placebo) i Multiple Myeloma, Autologous Transplantation | — | 2006-06-01 |
| Terminated | Study of the Effects of Fabrazyme Treatment on Lactation and Infants Fabry Disease, Alpha Galactosidase A Deficiency | Phase 4 | 2006-05-28 |
| Completed | A New Study to Follow-up Thyroid Cancer Patients Who Participated in a Previous Study, Which Compared the Succ Differentiated Thyroid Cancer | Phase 3 | 2006-05-01 |
| Completed | Subcutaneous Alemtuzumab (CAMPATH®, MabCampath®) in Relapsed/Refractory B-Cell Chronic Lymphocytic Leukemia B-Cell Chronic Lymphocytic Leukemia (B-CLL) | Phase 2 | 2006-05-01 |
| Completed | ZACTIMA (an Anti-EGFR / Anti-VEGF Agent) Combined With Docetaxel Compared to Docetaxel in Non-small Cell Lung Non-small Cell Lung Cancer, Lung Cancer | Phase 3 | 2006-05-01 |
| Terminated | Comparison Study of Rituximab Plus Sargramostim to Rituximab Alone for Relapsed Follicular B-cell Lymphoma, a Lymphoma, Follicular | Phase 2 | 2006-05-01 |
| Withdrawn | A Study in Patients With Fabry Disease Who Are on Chronic Hemodialysis Therapy for Treatment of End-stage Rena Fabry Disease | Phase 4 | 2006-04-01 |
| Completed | A Study of Clofarabine in Combination With Etoposide and Cyclophosphamide in Children With Acute Leukemias. Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, Relapsed Leukemia | Phase 1 / Phase 2 | 2006-03-01 |
| Completed | A Post-Market Study to Evaluate Adverse Event Incidence Rates in Patients With Skin of Color Undergoing Correc Facial Wrinkles | Phase 4 | 2006-02-01 |
| Completed | The Effect of Rituximab on Mobilization With AMD3100 (Plerixafor) Plus G-CSF in Patients With Relapsed or Refr Non-Hodgkin Lymphoma, Hodgkin Disease | Phase 2 | 2006-02-01 |
| Completed | E3 Breast Cancer Taxotere Combination Advanced Breast Cancer | Phase 2 | 2006-01-01 |
| Completed | Study to Demonstrate Equivalence of Sevelamer Carbonate Powder and Sevelamer HCl Tablets in Haemodialysis Pati Chronic Kidney Disease | Phase 3 | 2006-01-01 |
| Completed | Safety, Pharmacokinetics (PK), And Hematological Activity Of AMD3100 (Plerixafor) In Subjects With Renal Impai Renal Impairment | Phase 1 | 2006-01-01 |
| Completed | An Open Label Dose Titration of Sevelamer Carbonate Tabs 3 Times a Day in Hyperphosphatemic CKD Patients Not O Chronic Kidney Disease, Hyperphosphatemia | Phase 3 | 2006-01-01 |
| Terminated | Efficacy (Induction of Response/Remission) and Safety Study in Patients With Moderate to Severe Crohn's Diseas Crohn Disease | Phase 3 | 2006-01-01 |
| Completed | Study to Compare Sevelamer Carbonate Powder to Sevelamer Hydrochloride Tablets in Patients With CKD on Hemodia Kidney Diseases, Chronic Renal Insufficiency, End-Stage Renal Disease | Phase 3 | 2006-01-01 |
| Completed | Efficacy and Safety Study of SH T 586 in Combination With Rituximab to Treat Low-Grade NHL Lymphoma, Low-Grade | Phase 2 | 2005-12-01 |
| Completed | Safety and Effectiveness Study of rhGAA in Patients With Advanced Late-Onset Pompe Disease Receiving Respirato Pompe Disease (Late-onset), Glycogen Storage Disease Type II (GSD-II), Acid Maltase Deficiency Disease | Phase 3 | 2005-12-01 |
| Completed | Study of Aldurazyme® Replacement Therapy in Patients With Mucopolysaccharidosis I (MPS I) Disease Mucopolysaccharidosis I, Hurler Syndrome, Hurler-Scheie Syndrome | Phase 3 | 2005-12-01 |
| Completed | AMD3100 (Plerixafor) With G-CSF in Poor Mobilizing Adult Patients Who Previously Failed Hematopoietic Stem Cel Autologous Stem Cell Transplantation | Phase 2 | 2005-10-01 |
| Completed | A Study of AMD11070 in HIV-infected Patients Carrying X4-tropic Virus HIV Infections, X4 Tropic Virus | Phase 1 | 2005-10-01 |
| Completed | A Placebo-Controlled Study of Safety and Effectiveness of Myozyme (Alglucosidase Alfa) in Patients With Late-O Pompe Disease (Late-onset), Glycogen Storage Disease Type II (GSD-II), Acid Maltase Deficiency Disease | Phase 3 | 2005-09-01 |
| Completed | Phase I FOLFOX Combination Advanced Colorectal Carcinoma | Phase 1 | 2005-08-01 |
| Terminated | Safety Study of GMA161 in Patients With Idiopathic Thrombocytopenic Purpura (ITP) Idiopathic Thrombocytopenic Purpura | Phase 1 | 2005-08-01 |
| Completed | Phase I Irinotecan, 5-Fluorouracil and Leucovorin Combination Metastatic, Colorectal, Adenocarcinoma | Phase 1 | 2005-08-01 |
| Completed | Study of Safety and Efficacy of Doxercalciferol in Patients With Chronic Kidney Disease, Stage 3 or 4, and Sec Secondary Hyperparathyroidism, Renal Failure, Chronic Renal Insufficiency | Phase 4 | 2005-07-01 |
| Completed | ZD6474(Vandetanib) + Alimta Combo Study Carcinoma, Non-Small Cell Lung, Lung Cancer | Phase 1 | 2005-07-01 |
| Completed | Study of GC1008 in Patients With Idiopathic Pulmonary Fibrosis (IPF) Idiopathic Pulmonary Fibrosis | Phase 1 | 2005-07-01 |
| Completed | A Safety and Efficacy Study of Fabrazyme® Replacement Therapy in Patients With Cardiac Fabry Disease Fabry Disease | Phase 4 | 2005-07-01 |
| Completed | Study Comparing Thyrogen Versus a Modified Release of Recombinant Human Thyroid Stimulating Hormone Healthy | Phase 1 | 2005-06-01 |
| Completed | Extension Study of Patients With Infantile-Onset Pompe Disease Who Were Previously Enrolled in Protocol AGLU01 Glycogen Storage Disease Type II | Phase 2 / Phase 3 | 2005-06-01 |
| Completed | A Study of the Safety and Efficacy of Hylan G-F 20 (Synvisc) in Patients With Symptomatic Osteoarthritis of th Osteoarthritis, Knee, Musculoskeletal Diseases | Phase 3 | 2005-05-01 |
| Completed | Alemtuzumab/Fludarabine for Relapsed/Refractory B-cell Chronic Lymphocytic Leukemia (B-CLL) Leukemia, Lymphocytic, Chronic, B-Cell | Phase 2 | 2005-05-01 |
| Completed | Screening Protocol to Evaluate Acid Alpha-Glucosidase (GAA) Activity and GAA Gene Mutations in Patients With L Pompe Disease | — | 2005-05-01 |
| Completed | A Study of GT267-004 Versus Vancomycin and GT267-004 Versus Metronidazole in Patients With C. Difficile-Associ Clostridium Enterocolitis, Diarrhea | Phase 3 | 2005-04-01 |
| Completed | Evaluation of Thymoglobulin Induction and Reduced Doses of Calcineurin Inhibitors on Liver Transplant Rejectio Liver Dysfunction, Rejection, Transplant, Transplantation, Liver | Phase 2 | 2005-04-01 |
| Terminated | AMD3100 (Plerixafor) in Multiple Myeloma (MM) or Non-Hodgkin's Lymphoma (NHL) Patients Predicted to be Unable Multiple Myeloma, Lymphoma, Non-Hodgkin's | Phase 2 | 2005-04-01 |
| Completed | Cross-Over Study of Sevelamer Hydrochloride and Sevelamer Carbonate Chronic Kidney Disease | Phase 2 | 2005-03-01 |
| Completed | A Study of GT267-004 Versus Vancomycin and GT267-004 Versus Metronidazole in Patients With C.Difficile - Assoc Clostridium Enterocolitis, Pseudomembranous Colitis | Phase 3 | 2005-03-01 |
| Completed | Safety and Efficacy Study of Ad2/Hypoxia Inducible Factor (HIF)-1α/VP16 Gene Transfer in Patients With Intermi Intermittent Claudication, Peripheral Vascular Disease, Atherosclerosis | Phase 2 | 2005-02-01 |
| Completed | A Study of rhGAA in Patients With Late-Onset Pompe Disease Pompe Disease (Late-onset), Glycogen Storage Disease Type II (GSD-II), Acid Maltase Deficiency Disease | Phase 2 | 2005-02-01 |
| Completed | AMD3100 (Plerixafor) Given to NHL and MM Patients to Increase the Number of PBSCs When Given a Mobilizing Regi Multiple Myeloma, Lymphoma, Non-Hodgkin | Phase 2 | 2005-01-01 |
| Completed | Mobilization of Stem Cells With AMD3100 (Plerixafor) in Non-Hodgkin's Lymphoma Patients Lymphoma, Non-Hodgkin | Phase 3 | 2005-01-01 |
| Completed | Mobilization of Stem Cells With AMD3100 (Plerixafor) in Multiple Myeloma Patients Multiple Myeloma | Phase 3 | 2005-01-01 |
| Completed | ZD6474 Phase IIa Dose Finding Multicentre Study Non Small Cell Lung Carcinoma | Phase 2 | 2004-12-01 |
| Terminated | Safety and Efficacy Study in the Treatment of Pediatric Crohn's Disease Crohn Disease | Phase 1 / Phase 2 | 2004-12-01 |
| Completed | Study of Safety and Efficacy of Renagel® Compared With Calcium Acetate in Patients With Peritoneal Dialysis Peritoneal Dialysis, Chronic Kidney Disease | Phase 3 | 2004-12-01 |
| Completed | A Dose-optimization Study of Aldurazyme® (Laronidase) in Patients With Mucopolysaccharidosis I (MPS I) Disease Mucopolysaccharidosis I, Hurler's Syndrome, Hurler-Scheie Syndrome | Phase 4 | 2004-12-01 |
| Completed | Expanded Access Use of Myozyme (Alglucosidase Alfa) in Patients With Late-onset Pompe Disease Glycogen Storage Disease Type II, Glycogenosis 2 | N/A | 2004-11-01 |
| Completed | Efficacy and Tolerability of ZD6474 in Patients With Thyroid Cancer Thyroid Cancer | Phase 2 | 2004-11-01 |
| Completed | A Study of AAV-hAADC-2 in Subjects With Parkinson's Disease Parkinson's Disease | Phase 1 | 2004-11-01 |
| Completed | AMD3100 (Plerixafor) Added to a Mobilizing Regimen of Granulocyte-colony Stimulating Factor (G-CSF) to Increas Hodgkin's Disease | Phase 2 | 2004-11-01 |
| Terminated | Treatment With AMD3100 (Plerixafor) in MM Patients to Mobilize PBCs For Collection and for Transplantation Multiple Myeloma | Phase 2 | 2004-11-01 |
| Completed | Comparison of Hylastan to Methylprednisolone Acetate in Patients With Symptomatic Osteoarthritis of the Knee Osteoarthritis, Knee | Phase 3 | 2004-10-01 |
| Recruiting | Pompe Disease Registry Protocol Glycogen Storage Disease Type II, Pompe Disease | — | 2004-09-15 |
| Completed | Treatment With AMD3100 (Plerixafor) in Non-Hodgkin's Lymphoma and Multiple Myeloma Patients Lymphoma, Non-Hodgkin, Multiple Myeloma | Phase 2 | 2004-09-01 |
| Completed | Efficacy (Induction of Response/Remission) and Safety Study in Patients With Moderate to Severe Crohn's Diseas Crohn Disease | Phase 3 | 2004-09-01 |
| Completed | A Study Investigating the Relationship Between the Development of Laronidase Antibody and Urinary GAG (Glycosa Mucopolysaccharidosis I, Hurler's Syndrome, Hurler-Scheie Syndrome | Phase 4 | 2004-07-01 |
| Completed | Fludarabine (Fludara®) Plus Alemtuzumab (CAMPATH®, MabCampath®) vs Fludarabine Alone in B-Cell Chronic Lymphoc B-Cell Chronic Lymphocytic Leukemia | Phase 3 | 2004-07-01 |
| Terminated | Efficacy Study of Sargramostim in the Retreatment of Patients Who Have Crohn's Disease Who Have Previously Res Crohn Disease | Phase 3 | 2004-07-01 |
| Completed | A Study of Clofarabine in Older Patients With Acute Myeloid Leukemia (AML) for Whom Chemotherapy Is Not Suitab Acute Myeloid Leukemia | Phase 2 | 2004-06-01 |
| Completed | A Long Term Safety and Efficacy Study of Fabrazyme Replacement Therapy in Japanese Patients With Fabry Disease Fabry Disease | — | 2004-06-01 |
| Completed | Efficacy and Safety Study of Oral Fludarabine Phosphate in Combination With Mitoxantrone as First Line Treatme Non Hodgkin Lymphoma | Phase 2 | 2004-06-01 |
| Completed | Mobilization of Stem Cells With Plerixafor, Chemotherapy and G-CSF in Multiple Myeloma or Non-Hodgkin's Lympho Lymphoma, Non-Hodgkin, Multiple Myeloma | Phase 2 | 2004-04-01 |
| Completed | A Study of the Safety and Efficacy of Synvisc in Patients With Symptomatic Shoulder Osteoarthritis Osteoarthritis, Musculoskeletal Diseases | Phase 3 | 2004-04-01 |
| Completed | Trilostane for Androgen-Independent Prostate Cancer Prostate Cancer, Prostate Adenocarcinoma | Phase 2 | 2004-03-01 |
| Completed | Thymoglobulin to Prevent Acute Graft vs. Host Disease (GvHD) in Patients With Acute Lymphocytic Leukemia (ALL) Acute Myelogenous Leukemia (AML), Acute Lymphocytic Leukemia (ALL), Graft vs. Host Disease (GvHD) | N/A | 2004-03-01 |
| Terminated | A Safety and Efficacy Study of DENSPM in Patients With Liver Cancer Who Are Not Eligible for Surgical Care Carcinoma, Hepatocellular | Phase 1 / Phase 2 | 2004-03-01 |
| Completed | A Prospective, Observational Study in Patients With Late-Onset Pompe Disease Glycogen Storage Disease Type II | — | 2004-03-01 |
| Completed | Mobilization of Stem Cells With AMD3100 (Plerixafor) and G-CSF in Non-Hodgkin's Lymphoma and Multiple Myeloma Lymphoma, Non-Hodgkin, Multiple Myeloma | Phase 2 | 2004-03-01 |
| Completed | ZD6474 Alone or in Combination With Paclitaxel and Carboplatin in Subjects With Previously Untreated Locally A Carcinoma, Non-Small-Cell Lung | Phase 2 | 2004-02-01 |
| Completed | A Study of the Safety and Efficacy of Fabrazyme in Patients With Fabry Disease Fabry Disease | Phase 4 | 2004-01-01 |
| Completed | Vitalis Study - Observational Study on the Quality of Life in Patients Under Treatment for B-Chronic Lymphocyt Leukemia, B-Cell, Chronic | — | 2004-01-01 |
| Terminated | Subcutaneously Administered CAMPATH in CD52 Expressing Hematologic Malignancies Hematologic Malignancies | Phase 1 | 2003-12-01 |
| Terminated | Rituximab Plus CAMPATH in Patients With Relapsed/Refractory Low-Grade or Follicular, CD20-positive, B-cell NHL Non-Hodgkin's Lymphoma | Phase 1 / Phase 2 | 2003-12-01 |
| Approved For Marketing | Expanded Access Use of Myozyme (Alglucosidase Alfa) in Patients With Infantile-onset Pompe Disease Glycogen Storage Disease Type II, Glycogenosis 2 | — | 2003-12-01 |
| Completed | A Phase II, Open-Label Study of Clofarabine in Paediatric Patients With Refractory/Relapsed Acute Lymphoblasti Acute Lymphoblastic Leukemia | Phase 2 | 2003-12-01 |
| Completed | Study of ILX651 in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Carcinoma Non-Small-Cell Lung Carcinoma | Phase 2 | 2003-12-01 |
| Completed | Mucopolysaccharidosis I (MPS I) Registry Mucopolysaccharidosis I (MPS I) | — | 2003-11-20 |
| Completed | A Study of the Safety and Efficacy of Synvisc in Patients With Symptomatic Ankle Osteoarthritis Osteoarthritis | Phase 3 | 2003-11-01 |
| Completed | A Study of the Safety and Efficacy of Synvisc and Depo-Medrol in Patients With Osteoarthritis of the Hip Osteoarthritis, Hip, Musculoskeletal Diseases | Phase 3 | 2003-11-01 |
| Approved For Marketing | Access Program for Use of AMD3100 to Increase Peripheral Blood Stem Cells for Transplantation in Patients Who Autologous Stem Cell Transplant | — | 2003-10-01 |
| Completed | Study of Oral Clofarabine Administered Daily for 5 Days in Adult Patients With Refractory Solid Tumors Solid Tumors | Phase 1 | 2003-10-01 |
| Completed | Iron Balance Study of DFO and GT56-252 in Patients With Transfusional Iron Overload Secondary to Beta-Thalasse Beta-Thalassemia | Phase 1 / Phase 2 | 2003-09-01 |
| Completed | Study of ILX651 in Patients With Inoperable Locally Advanced or Metastatic Melanoma Melanoma | Phase 2 | 2003-08-01 |
| Terminated | An Investigation Into the Short Term Effect of APOMINE in Patients With Osteoporosis or Low Bone Mass Osteoporosis | Phase 1 / Phase 2 | 2003-08-01 |
| Completed | Study in Patients With Crohn's Disease Who Are Steroid Dependent, Despite Previous Unsuccessful Attempts to Re Crohn Disease | Phase 2 | 2003-07-01 |
| Completed | A Study to Evaluate the Effect of Thymoglobulin and Reduced Doses of Steroids to Prevent Renal Transplant Reje Renal Transplantation, Graft Rejection | Phase 2 | 2003-06-01 |
| Terminated | Efficacy of Seprapack Sinus Dressing Versus No Dressing in the Prevention of Intranasal Adhesions Following Si Chronic Sinusitis | N/A | 2003-06-01 |
| Completed | A Study of the Safety and Efficacy of Fabrazyme in Patients With Fabry Disease Fabry Disease | Phase 2 | 2003-06-01 |
| Completed | This Study is to Compare the Efficacy of ZD6474 and ZD1839 in Subjects With NSCLC. Carcinoma, Non-Small-Cell Lung | Phase 2 | 2003-05-01 |
| Completed | ZD6474 in Treating Patients With Small Cell Lung Cancer Lung Cancer | Phase 2 | 2003-05-01 |
| Completed | Extension Study of Long-term Safety and Efficacy of Myozyme in Patients With Pompe Disease Who Were Previously Pompe Disease Infantile-Onset, Glycogen Storage Disease Type II | Phase 2 | 2003-04-01 |
| Completed | A Study of the Safety and Efficacy of rhGAA in Patients With Infantile-onset Pompe Disease Glycogen Storage Disease Type II | Phase 2 / Phase 3 | 2003-04-01 |
| Completed | Extension Study of Long-term Safety and Efficacy of Myozyme for a Single Patient With Pompe Disease Who Were P Pompe Disease Late-Onset, Glycogen Storage Disease Type II GSD II | Phase 2 | 2003-04-01 |
| Completed | Study to Compare Once A Day Sevelamer Dosing With Three Times Per Day Sevelamer Dosing Chronic Kidney Disease | Phase 2 | 2003-03-01 |
| Completed | rhGAA in Patients With Infantile-onset Glycogen Storage Disease-II (Pompe Disease) Glycogen Storage Disease Type II, Pompe Disease, Acid Maltase Deficiency Disease | Phase 1 / Phase 2 | 2003-02-01 |
| Terminated | Open-label Trial of Leukine in Active Crohn's Disease Crohn Disease | Phase 2 | 2003-02-01 |
| Completed | Fludara (Oral) Phase II Study for Indolent Lymphoma Lymphoma | Phase 2 | 2003-02-01 |
| Completed | A Study of the Safety and Pharmacokinetics of rhGAA in Siblings With Glycogen Storage Disease Type II Glycogen Storage Disease Type II, Pompe Disease, Acid Maltase Deficiency Disease | Phase 2 | 2003-01-01 |
| Completed | A Phase II Study Comparing Low- and High-Dose Alemtuzumab and High-Dose Rebif® in Patients With Early, Active Multiple Sclerosis, Relapsing-Remitting | Phase 2 | 2002-12-01 |
| Terminated | Phase I/II Study of CAMPATH in Patients With Relapsing or Refractory Non-Hodgkin's Lymphoma Non-Hodgkins Lymphoma | Phase 1 / Phase 2 | 2002-12-01 |
| Terminated | Severe Renal Disease Study in Fabry Patients Treated With Fabrazyme Fabry Disease, Chronic Kidney Disease, Stage IV (Severe) | Phase 2 | 2002-12-01 |
| Terminated | Study to Examine the Safety and Effectiveness of Implanted Skeletal Muscle Cells (Cells Removed From the Thigh Ischemic Heart Failure, Ischemic Heart Disease, Ischemic Cardiomyopathy | Phase 2 | 2002-11-01 |
| Completed | Safety/Efficacy of a Vaccine Prepared From Dendritic Cells Combined With Tumor Cells to Treat Advanced Kidney Carcinoma, Renal Cell | Phase 1 / Phase 2 | 2002-11-01 |
| Completed | Efficacy Study of ZD6474 to Treat Multiple Myeloma Cancer Multiple Myeloma | Phase 2 | 2002-10-01 |
| Completed | A Study of Fabrazyme in Pediatric Patients With Fabry Disease Fabry Disease | Phase 2 | 2002-10-01 |
| Completed | This Study is to Assess the Efficacy and Safety of ZD6474 in Subjects With Non-small Cell Lung Cancer. Non-Small Cell Lung Cancer (NSCLC, Locally Advanced or Metastatic, Second-line | Phase 2 | 2002-10-01 |
| Completed | A Study Evaluating the Safety and Pharmacokinetics of Aldurazyme® (Laronidase) in MPS I Patients Less Than 5 Y Mucopolysaccharidosis I, Hurler Syndrome, Hurler-Scheie Syndrome | Phase 2 | 2002-10-01 |
| Completed | Clofarabine in Adult Patients With Advanced Solid Tumors Solid Tumors, Leukemia, Lymphocytic, Acute, Pediatric, Leukemia, Lymphocytic, Acute, Adult | Phase 1 | 2002-08-01 |
| Completed | A Double-blinded Evaluation of Safety and Efficacy of Hylaform and Hylaform Plus Compared to Zyplast. Facial Wrinkles | N/A | 2002-06-01 |
| Completed | Phase II Study of Clofarabine in Pediatric Acute Myelogenous Leukemia (AML) Patients Leukemia, Myelocytic, Acute, Pediatric | Phase 2 | 2002-05-01 |
| Completed | This Study is to Assess the Efficacy and Safety of ZD6474 in Subjects With Metastatic Breast Cancer Breast Neoplasms, Metastases, Neoplasm | Phase 2 | 2002-05-01 |
| Completed | Phase II Study of Clofarabine in Adult Patients With Refractory or Relapsed Acute Myelogenous Leukemia Acute Myelogenous Leukemia | Phase 2 | 2002-05-01 |
| Completed | Phase II Study of Clofarabine in Pediatric Acute Lymphoblastic Leukemia (ALL) Leukemia, Lymphoblastic, Acute, Pediatric | Phase 2 | 2002-05-01 |
| Completed | A Study of GT160-246 Versus Vancomycin in Patients With Clostridium Difficile-Associated Diarrhea Clostridium Difficile-Associated Diarrhea, Clostridium Enterocolitis, Clostridium Difficile Diarrhea | Phase 2 | 2002-02-01 |
| Completed | Comparison of the Safety and Successful Ablation of Thyroid Remnant in Post-thyroidectomized Euthyroid Patient Thyroid Neoplasms | Phase 3 | 2001-12-01 |
| Completed | Safety and Efficacy of Cerezyme® Infusions Every 4 Weeks Versus Every 2 Weeks in Type 1 Gaucher Disease Gaucher Disease, Type 1, Cerebroside Lipidosis Syndrome, Glucocerebrosidase Deficiency Disease | Phase 4 | 2001-12-01 |
| Recruiting | Fabry Disease Registry & Pregnancy Sub-registry Fabry Disease | — | 2001-07-31 |
| Completed | Efficacy/Safety of Frontline Alemtuzumab (Campath, MabCampath) vs Chlorambucil in Patients With Progressive B- B Cell Chronic Lymphocytic Leukemia | Phase 3 | 2001-07-01 |
| Completed | Safety and Efficacy of Recombinant Human Acid Alpha-Glucosidase in the Treatment of Classical Infantile Pompe Pompe Disease, Glycogen Storage Disease Type II, Acid Maltase Deficiency Disease | Phase 2 | 2001-05-01 |
| Completed | Phase 3 Extension Study of the Safety and Efficacy of Aldurazyme® (Laronidase) in Mucopolysaccharidosis I (MPS Mucopolysaccharidosis I, Hurler's Syndrome, Hurler-Scheie Syndrome | Phase 3 | 2001-05-01 |
| Completed | A Study of NM-3 Administered Orally in Patients With Advanced Solid Tumors. Neoplasms | Phase 1 | 2001-05-01 |
| Completed | Dialysis Clinical Outcomes Revisited (DCOR) Trial Chronic Kidney Disease | Phase 4 | 2001-03-01 |
| Completed | A Study of the Safety and Efficacy of Fabrazyme (Agalsidase Beta) as Compared to Placebo in Patients With Adva Fabry Disease | Phase 4 | 2001-02-01 |
| Completed | Clinical Study of Aldurazyme in Patients With Mucopolysaccharidosis (MPS) I Mucopolysaccharidosis I, Hurlers Syndrome, Hurler-Scheie Syndrome | Phase 3 | 2000-12-01 |
| Completed | A Study to Confirm the Efficacy and Safety of Fludarabine Phosphate Administered in Untreated Chronic Lymphocy Leukemia, Lymphocytic, Chronic, B-Cell | Phase 4 | 2000-11-01 |
| Unknown | Vaccine Therapy in Treating Patients Who Have Stage II, Stage III, or Stage IV Melanoma Melanoma (Skin) | Phase 1 / Phase 2 | 2000-11-01 |
| Completed | Antithymocyte Globulin Compared With Supportive Care in Treating Patients With Myelodysplastic Syndrome Myelodysplastic Syndromes | Phase 2 | 2000-09-01 |
| Completed | An Open-label, Prospective, Randomized, Multi-center, Phase II Comparative Trial of Thymoglobulin Versus Simul Cadaveric Donor Renal Transplantation, Acute Renal Allograft Rejection, Induction Therapy | Phase 2 | 2000-05-01 |
| Completed | A Study of the Safety and Efficacy of Fabrazyme in Patients With Fabry Disease Fabry Disease | Phase 3 | 1999-10-01 |
| Withdrawn | ILX-295501 in Treating Patients With Stage III or Stage IV Ovarian Cancer That Has Not Responded to Previous T Fallopian Tube Cancer, Metastatic Cancer, Ovarian Cancer | Phase 2 | 1999-05-01 |
| Completed | SR-45023A in Treating Patients With Locally Advanced or Metastatic Solid Tumors Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | 1999-04-01 |
| Unknown | Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Stage III or Stage IV Melanoma Melanoma (Skin) | Phase 1 / Phase 2 | 1999-03-01 |
| Completed | SR-45023A in Treating Patients With Advanced Solid Tumors Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | 1998-08-01 |
| Completed | Seprafilm in the Reduction of Incidence of Bowel Obstruction in General Surgery Intestinal Obstruction, Digestive System Surgical Procedures | N/A | 1998-06-01 |
| Withdrawn | Aminopterin in Treating Patients With Recurrent or Refractory Endometrial Cancer Endometrial Cancer | Phase 2 | 1998-01-01 |
| Completed | A Multicenter Study of the Efficacy of Cerezyme in Testing Skeletal Disease in Patients With Type I Gaucher Di Gaucher Disease Type I, Cerebroside Lipidosis Syndrome, Clucocerebrosidase Deficiency Disease | Phase 4 | 1997-12-01 |
| Completed | Phase 2, Double-blind, Randomized, Controlled Multi-center Clinical Trial of the Safety and Efficacy of Transp Parkinson's Disease | Phase 2 | 1997-08-01 |
| Completed | Chemotherapy in Treating Patients With Advanced or Metastatic Solid Tumors Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | 1997-08-01 |
| Completed | Aminopterin in Treating Patients With Refractory Leukemia Leukemia | Phase 2 | 1997-07-01 |
| Recruiting | International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry Gaucher Disease, Cerebroside Lipidosis Syndrome, Glucocerebrosidase Deficiency Disease | — | 1991-04-01 |
| Completed | Safety, Tolerability, and Pharmacokinetics of CAT-192 (Human Anti-TGF-Beta1 Monoclonal Antibody) in Patients W Systemic Sclerosis, Scleroderma | Phase 1 / Phase 2 | — |
| Completed | Study of ILX651 in Patients With Hormone-Refractory Prostate Cancer Previously Treated With Docetaxel Hormone-refractory Prostate Cancer | Phase 2 | — |
| Approved For Marketing | Alglucosidase Alfa Temporary Access Program Glycogen Storage Disease Type II (GSD-II), Pompe Disease (Late-Onset), Acid Maltase Deficiency Disease | — | — |
| No Longer Available | This is a Multi-center, Single Arm, Open Label Study Intended to Provide Expanded Access to Plerixafor for Pat Non-Hodgkin's Lymphoma, Hodgkin's Disease, Multiple Myeloma | — | — |
| Withdrawn | AMD3100 With Busulfan, Fludarabine and Thymoglobulin for Allogeneic Stem Cell Transplant for AML and MDS Acute Myelogenous Leukemia, Myelodysplastic Syndromes | Phase 1 / Phase 2 | — |
| Completed | A Study of Mitoguazone Dihydrochloride in Patients With AIDS-Related Non-Hodgkin's Lymphoma Lymphoma, Non-Hodgkin, HIV Infections | Phase 2 | — |