NCT00364351

Efficacy Trial Comparing ZD6474 With Erlotinib in NSCLC After Failure of at Least One Prior Chemotherapy

A Phase III, International, Randomised, Double Blind, Parallel-Group Study to Assess the Efficacy of Zactima™ Versus Tarceva® in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer After Failure of at Least One Prior Chemotherapy

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 1,574 (actual)
• Sponsor: Genzyme, a Sanofi Company · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To determine if ZD6474 a new investigational drug, is effective in treating Non Small Lung Cancer and if so, how it compares with another type of anti cancer therapy chemotherapy, Erlotinib

Conditions

• Non Small Cell Lung Cancer

Interventions

Type	Name	Description
DRUG	Vandetanib	once daily oral tablet
DRUG	Erlotinib	oral dose

Timeline

• Start date: 2006-08-01
• Primary completion: 2008-09-01
• Completion: 2016-11-01
• First posted: 2006-08-15
• Last updated: 2018-01-25
• Results posted: 2011-05-24

Locations

153 sites across 22 countries: United States, Argentina, Australia, Brazil, Canada, China, Denmark, France, Germany, Hong Kong, India, Indonesia, Italy, Mexico, Netherlands, Norway, Philippines, South Korea, Spain, Taiwan, Thailand, United Kingdom