Clinical Trials Directory

Trials / Completed

CompletedNCT00206674

Efficacy (Induction of Response/Remission) and Safety Study in Patients With Moderate to Severe Crohn's Disease

Phase 3 Randomized, Double-Blind, Placebo Controlled Induction Study of Sargramostim (Leukine®) in Patients With Active Crohn's Disease

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
286 (actual)
Sponsor
Genzyme, a Sanofi Company · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate if Leukine can induce clinical response or remission in patients with Crohn's disease.

Detailed description

On 29 May 2009, Bayer began transitioning the sponsorship of this trial to Genzyme. NOTE: This study was originally posted by sponsor Berlex, Inc. Berlex, Inc. was renamed to Bayer HealthCare, Inc.

Conditions

Interventions

TypeNameDescription
DRUGSargramostim (Leukine)6µg/kg SARGRAMOSTIM subcutaneous daily for 8 weeks
DRUGPlaceboSterile liquid solution, inactive excipient only subcutaneous daily for 8 weeks

Timeline

Start date
2004-09-01
Primary completion
2006-06-01
Completion
2006-06-01
First posted
2005-09-21
Last updated
2013-12-04

Locations

70 sites across 9 countries: Argentina, Australia, Brazil, Canada, New Zealand, Russia, Switzerland, Ukraine, United Kingdom

Source: ClinicalTrials.gov record NCT00206674. Inclusion in this directory is not an endorsement.

Efficacy (Induction of Response/Remission) and Safety Study in Patients With Moderate to Severe Crohn's Disease (NCT00206674) · Clinical Trials Directory