Clinical Trials Directory

Trials / Terminated

TerminatedNCT00206713

Efficacy Study of Sargramostim in the Retreatment of Patients Who Have Crohn's Disease Who Have Previously Responded to Treatment With Sargramostim

Phase 3 Randomized, Double-Blind, Placebo-Controlled Multicenter Retreatment Study of Sargramostim (Leukine®) in Patients With Active Crohn's Disease and Prior Treatment Response to Sargramostim

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
264 (actual)
Sponsor
Genzyme, a Sanofi Company · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate whether treatment with Leukine in patients with Crohn's disease who have previously responded to Leukine can be helped again, once they have relapsed.

Detailed description

On 29 May 2009, Bayer began transitioning the sponsorship of this trial to Genzyme. NOTE: This study was originally posted by sponsor Berlex, Inc. Berlex, Inc. was renamed to Bayer HealthCare, Inc.

Conditions

Interventions

TypeNameDescription
DRUGSargramostim (Leukine)6 μg/kg sargramostim administered SC once daily for 8 weeks
DRUGPlaceboPlacebo administered SC once daily during the randomized retreatment phase.

Timeline

Start date
2004-07-01
Primary completion
2006-10-01
Completion
2006-10-01
First posted
2005-09-21
Last updated
2013-12-04

Locations

7 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00206713. Inclusion in this directory is not an endorsement.