Clinical Trials Directory

Trials / Completed

CompletedNCT00002348

A Study of Mitoguazone Dihydrochloride in Patients With AIDS-Related Non-Hodgkin's Lymphoma

Phase II Evaluation of Mitoguazone Dihydrochloride in Patients With Refractory or Relapsed Non-Hodgkin's Lymphoma Associated With Acquired Immunodeficiency Syndrome

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
Sponsor
Genzyme, a Sanofi Company · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

To estimate the response rate, response duration, clinical benefit, and toxicity of mitoguazone dihydrochloride (MGBG) in patients with AIDS-related refractory or relapsing non-Hodgkin's lymphoma (NHL).

Detailed description

Patients receive infusions of MGBG on days 1 and 8 and every 2 weeks thereafter. It is suggested that a lumbar puncture be performed to evaluate for leptomeningeal disease.

Conditions

Interventions

TypeNameDescription
DRUGMitoguazone

Timeline

First posted
2001-08-31
Last updated
2020-12-19

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00002348. Inclusion in this directory is not an endorsement.

A Study of Mitoguazone Dihydrochloride in Patients With AIDS-Related Non-Hodgkin's Lymphoma (NCT00002348) · Clinical Trials Directory