NCT01460147

Osteoporosis and MRI Study in Hemophilia

Bone and Joint Health in an Adult Hemophilia Population

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 3 (actual)
• Sponsor: Baxalta now part of Shire · Industry
• Sex: Male
• Age: 25 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate bone mineral density in adult subjects with hemophilia versus a comparator population without hemophilia (non-hemophilia age- and gender-matched database) by using the following diagnostic means: dual-energy X-ray absorptiometry (DXA) scanning, clinical scales, quality of life (QOL) scales and biomarkers. In addition to this osteoporosis study, hemophilic arthropathy of the knee with respect to loss of knee cartilage will also be explored by using magnetic resonance imaging (MRI substudy). No investigational product will be dispensed.

Conditions

• Bone Mineral Density
• Hemophilia A
• Hemophilia B

Interventions

Type	Name	Description
OTHER	DXA scan + MRI	This is a non-drug study. Subjects will receive a dual-energy X-ray absorptiometry (DXA) scan (in the main osteoporosis study) and will undergo magnetic resonance imaging (in the MRI substudy).

Timeline

• Start date: 2011-10-30
• Primary completion: 2012-04-13
• Completion: 2012-04-13
• First posted: 2011-10-26
• Last updated: 2021-04-22

Locations

1 site across 1 country: United States