Clinical Trials Directory

Trials / Terminated

TerminatedNCT02895945

BAX 802 in CHA With Inhibitors

A Phase 3, Multicenter, Open-label Study of the Efficacy and Safety of B-Domain Deleted Recombinant Porcine Factor VIII (BAX 802) in Subjects With Congenital Hemophilia A With Factor VIII Inhibitors Undergoing Surgical or Other Invasive Procedures

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
8 (actual)
Sponsor
Baxalta now part of Shire · Industry
Sex
Male
Age
12 Years – 75 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the efficacy and safety of BAX 802 in males with congenital hemophilia A (CHA) with inhibitors who are undergoing major or minor elective surgical, dental, or other invasive procedures.

Conditions

Interventions

TypeNameDescription
BIOLOGICALAntihemophilic Factor (Recombinant), Porcine Sequence (BAX 802)In case of major surgery, FVIII target level is ≥80% for major surgeries/ procedures and ≥50% for minor surgeries/ procedures.

Timeline

Start date
2016-12-22
Primary completion
2021-01-22
Completion
2021-01-22
First posted
2016-09-12
Last updated
2021-10-20
Results posted
2021-10-20

Locations

24 sites across 12 countries: United States, Bulgaria, Canada, Germany, Italy, Netherlands, Norway, Poland, Russia, South Africa, Spain, Turkey (Türkiye)

Regulatory

Source: ClinicalTrials.gov record NCT02895945. Inclusion in this directory is not an endorsement.

BAX 802 in CHA With Inhibitors (NCT02895945) · Clinical Trials Directory