| Not Yet Recruiting | Viromes in Infants Presenting With a Septic Syndrome NCT07470541 | University Hospital, Montpellier | N/A |
| Not Yet Recruiting | Neuroendocrine Response in Pediatric Febrile Seizures NCT07463222 | Aydin Adnan Menderes University | — |
| Not Yet Recruiting | Antipyretic Therapy With and Without Cold Sponging NCT07426744 | Muhammad Aamir Latif | N/A |
| Recruiting | Assessing the Effectiveness of Large Language Model (LLM)-Enabled Nurse Treatment Planning in 2 Indian Distric NCT07432893 | Sarah Nabia | N/A |
| Recruiting | Safety of RSV Preventive Monoclonal Antibody NCT07158814 | Duke University | Phase 4 |
| Recruiting | Optimizing the Care Pathway of Febrile Children Via Capillary C-reactive Protein Assay in Primary Care NCT06910631 | Centre Hospitalier Universitaire de Nīmes | N/A |
| Not Yet Recruiting | Caspase-1 Activity, IL-1beta, and IL-18 in Patients With FMF NCT06981520 | Hitit University | — |
| Completed | Online Training to Improve Parents' Fever Management Practices NCT07061327 | Recep Tayyip Erdogan University | N/A |
| Completed | Fever In Palliative Care NCT07106073 | Stefania Cheli | — |
| Completed | Bioequivalence Study of Paracetamol With Oral Single Dose Administration in Healthy Adult Subjects Under Fasti NCT06855576 | HALEON | Phase 1 |
| Completed | Efficacy of Levofloxacin Versus Ciprofloxacin in the Treatment of Childhood Typhoid Fever NCT07150065 | Avicenna Medical College Lahore | Phase 2 |
| Recruiting | Continuos Body Temperature Monitoring NCT06447337 | Baby FM Doo | — |
| Recruiting | Prescription Antipyretics to Decrease Unscheduled Return Visits In A Pediatric Emergency Department NCT07074912 | University of Texas at Austin | N/A |
| Recruiting | The Impact of Local Anesthetic Solution Temperature on Epidural-related Maternal Fever NCT06682416 | The First Affiliated Hospital of Soochow University | N/A |
| Recruiting | TriVerity™ for Improved Management of Emergency Department (ED) Patients With Suspected Infections NCT06637904 | Inflammatix | N/A |
| Completed | Evaluation of the Risk of Infection During Fever in Labor NCT06517290 | Assistance Publique - Hôpitaux de Paris | — |
| Recruiting | Sulfamethoxazole Prophylaxis Duration After Renal Transplantation NCT07231770 | Anhui Provincial Hospital | N/A |
| Recruiting | Effect of Intravenous Vitamin C on Intrapartum Maternal Fever After Epidural Labor Analgesia NCT06354582 | Kunyue Li | Phase 4 |
| Recruiting | Fever Education Given to Parents of Children Presenting to the Emergency Department With Fever NCT06599853 | Merve YETİMOĞLU | N/A |
| Completed | AION BIOSYSTEMS, INC. Tempshield for Continuous Tempreature Monitoring NCT07145541 | AION Biosystems | N/A |
| Completed | Tympanic Thermometers Accuracy NCT06103604 | Istituto Ortopedico Rizzoli | — |
| Unknown | Treatment of Hyperpyrexia and in the Pediatric Emergency Department (FEVER_ED) NCT06194383 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Completed | Comparison of the Efficacy of Paracetamol and Ibuprofen in the Management of Fever in Sepsis Patients NCT06061575 | Ankara City Hospital Bilkent | Phase 4 |
| Completed | Safety of Simultaneous mRNA COVID-19 Vaccine With Other Childhood Vaccines in Young Children NCT06038617 | Duke University | Phase 4 |
| Unknown | Checklists Resuscitation Emergency Department NCT05649891 | Region Skane | N/A |
| Enrolling By Invitation | Analysis of the Virtual Acute Care at Home Experience NCT05952999 | OSF Healthcare System | — |
| Recruiting | Remote Temperature Monitoring of Patients At Risk for Developing Fever NCT06752512 | AION Biosystems | N/A |
| Withdrawn | Use of Malaria Rapid Diagnostic Tests as a Decision Aid for the Management of Fever by International Travelers NCT02900079 | Institute of Tropical Medicine, Belgium | — |
| Completed | Timing of Surgery in Pediatric Patients Following Fever Recovery: a Prospective Cohort Study NCT06568809 | Second Affiliated Hospital of Wenzhou Medical University | — |
| Unknown | A Combinatorial Biomarker for Infection Diagnosis in Children NCT05971901 | Universität des Saarlandes | — |
| Completed | Validation of the Masimo INVSENSOR00063 in Febrile and Afebrile Subejcts NCT05787782 | Masimo Corporation | N/A |
| Completed | NC Thermometer (Gen 3) ISO 80601-2-56 Validation NCT05721131 | Natural Cycles | — |
| Completed | Video and Brochure and Discharge Instructions for Childhood Fever in the Pediatric Emergency Department NCT05929131 | Bartın Unıversity | N/A |
| Completed | Evaluation of the Effectiveness of the Training Given to Mothers With 0-5 Age Group Children for Fire Manageme NCT06043479 | Okan University | N/A |
| Completed | Calibration and Validation of the Masimo Temperature Device in Febrile Patients NCT05674344 | Masimo Corporation | N/A |
| Recruiting | Observational Study About In-patients Admitted With Fever NCT05422651 | Xiangya Hospital of Central South University | — |
| Completed | Alleviation of Common Cold Symptoms NCT06106880 | Applied Biological Laboratories Inc | Phase 1 |
| Recruiting | Transcriptomic Responses for the Identification of Pathogens NCT04878549 | University of Sheffield | — |
| Active Not Recruiting | Tympanic Thermometer Study NCT06556628 | Baxter Healthcare Corporation | — |
| Completed | Utility of 18F-FDG PET/CT for Suspected Infection in the Inpatient Setting: a Single Centre Retrospective Coho NCT07430475 | University of Adelaide | — |
| Unknown | The Application of a Wireless Sensor Technology for Vital Statistics in CHILDREN AND ADULTS NCT01845506 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Completed | Evaluation of Knowledge About Fever After Consultation in the Pediatric Emergency Department NCT04925401 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Fever Management in Children With Febrile Neutropenia NCT05189236 | Acibadem University | N/A |
| Unknown | Home Blood Pressure Monitoring Before and After COVID-19 Vaccination in Patients at High Risk of Cardiovascula NCT05033613 | National Taiwan University Hospital | — |
| Completed | Link Between Eosinopenia and Bacterial Infections in the Elderly Subject Hospitalized in Geriatrics NCT04363138 | Gérond'if | — |
| Completed | Epidural Analgesia and Maternal Fever During Labor NCT04940091 | Peking University First Hospital | — |
| Completed | Treatment Of Fever In The Emergency Department NCT05814302 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Withdrawn | COVID-19 Epidemic Response Study NCT04357496 | CENTOGENE GmbH Rostock | — |
| Completed | Prospective Trial for Clinical Validation of "QOCA Disposable BLE Thermometer " NCT05014152 | Chang Gung Memorial Hospital | N/A |
| Completed | Study of Hesperidin Therapy on COVID-19 Symptoms (HESPERIDIN) NCT04715932 | Montreal Heart Institute | Phase 2 |
| Unknown | Thales Thermography Triage (3T) - Pilot Project NCT04792450 | NHS Greater Clyde and Glasgow | — |
| Completed | The Effect of Methods Used in Oral Antipyretic Administration on the Vital Findings of the Child With Fever NCT05366049 | Istanbul University - Cerrahpasa | N/A |
| Completed | The Effect of Video Education to the Febrile Child on the Knowledge, Attitudes and Behaviors of the Parents. NCT05707624 | Eskisehir Osmangazi University | N/A |
| Completed | Study of an App to Facilitate Communication With Parents of Febrile Infants NCT04328909 | Yale University | N/A |
| Completed | Host RNA Profiles to Detect Infections in Young Infants NCT04823026 | Rigshospitalet, Denmark | — |
| Completed | BNO 1030 Extract (Imupret) in the Treatment of Mild Forms of COVID-19 NCT04797936 | Ivano-Frankivsk National Medical University | Phase 4 |
| Completed | Knowledge, Attitude and Practice of Dental Students About COVID-19 NCT04449081 | Melaka Manipal Medical College | — |
| Suspended | Development of a Fever Detection Algorithm Based on Non-invasive Skin-based Sensor Values in Infants up to 18 NCT04654559 | greenTEG AG | N/A |
| Completed | Impact of Swab Site and Sample Collector on Testing Sensitivity for COVID-19 Virus in Symptomatic Individuals NCT04321369 | UnitedHealth Group | — |
| Unknown | Modifications of Heart Murmurs and Cardiac Output During Fever NCT04306991 | University Hospital, Angers | N/A |
| Withdrawn | Active Temperature Management After Cardiac Surgery and Its Effect on Postoperative Cognitive Dysfunction NCT03947671 | Virginia Commonwealth University | Phase 2 |
| Enrolling By Invitation | LázBarát™ (FeverFriend™) Projekt: Attitude Toward Fever and Its Change in the Healthcare System NCT04633603 | University of Pecs | — |
| Terminated | Fever Algorithm Development of a Non-invasive Wearable Core Body Temperature Sensor System in Intensive Care U NCT04182945 | greenTEG AG | N/A |
| Completed | Pilot Study Comparison Of Intravenous Ibuprofen And Intravenous Paracetamol In Management Of Pediatric Fever NCT04123717 | Hamad Medical Corporation | EARLY_Phase 1 |
| Completed | Assessment of Labour Progress by Intrapartum Ultrasound NCT04651309 | Kaplan Medical Center | N/A |
| Completed | Using Video for Triage of Children With Fever at the Medical Helpline 1813 in Copenhagen, Denmark NCT04074239 | Emergency Medical Services, Capital Region, Denmark | N/A |
| Terminated | Interest of the Presepsin Assay as a Biomarker of Bacterial Infection, in the Management of Newborns and Infan NCT04076345 | University Hospital, Clermont-Ferrand | — |
| Completed | Improving Safety of Diagnosis and Therapy in the Inpatient Setting NCT04393909 | Brigham and Women's Hospital | N/A |
| Completed | Pneumocystis Primary Infection in Non-immunosuppressed Infants NCT03740646 | University Hospital, Brest | — |
| Completed | Aggressive Antipyretics for Fever Reduction in CNS Malaria NCT03399318 | University of Rochester | Phase 2 |
| Completed | Comparison of the Efficacy of Intravenous Paracetamol and Ibuprofen in the Treatment of Fever Due to Upper Res NCT03918135 | Pamukkale University | Phase 4 |
| Completed | Efficacy of Bromocriptine For Fever Reduction in Acute Neurologic Injury NCT03496545 | University of California, San Francisco | Phase 1 / Phase 2 |
| Completed | Clinical Accuracy of the welloStationX NCT03758157 | Wello Inc. | — |
| Completed | Fever Infants and Therapeutic Education in Emergency Department NCT03706599 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Non-specific Effects of Rabies Vaccine NCT03656198 | Ross University School of Veterinary Medicine | Phase 4 |
| Completed | Bedside Ultrasound Predicts Progression of Severity of Disease in Dengue Fever NCT03632486 | Timothy Gleeson | — |
| Completed | Immediate Fever During Anaesthesia Recovery After Surgical Procedure With Scoliosis NCT06405659 | Affiliated Hospital of Guangdong Medical University | — |
| Completed | m-Health System for Tracking Kangaroo Mother Care and Temperature in Southern India NCT04929977 | St. John's Research Institute | N/A |
| Completed | A Safety Study For Prevenar 13 Among Chinese Children NCT03656939 | Pfizer | — |
| Completed | Evaluation of Efficacy and Safety of Subcutaneous Acetaminophen NCT03635684 | Saint-Joseph University | Phase 2 |
| Completed | Use of NGS Cell-free Pathogen Test for Identification of Low Risk Fever & Neutropenia in Pediatric Patients NCT03530072 | Karius, Inc. | — |
| Completed | Clinical Evaluation of the FilmArray® Global Fever (GF) Panel NCT02968355 | BioFire Defense LLC | — |
| Completed | Transnasal Induction of Normothermia in Febrile Stroke Patients NCT03360656 | CoolTech LLC | N/A |
| Completed | Medication Education for Dosing Safety NCT03223246 | Massachusetts General Hospital | N/A |
| Completed | Metformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chr NCT02948283 | City of Hope Medical Center | Phase 1 |
| Completed | Fever After Simultaneous Versus Sequential Vaccination in Young Children NCT03165981 | Duke University | Phase 4 |
| Completed | Safety and Pharmacokinetic Study of Intravenous Ibuprofen in Pediatric Patients NCT02583399 | Cumberland Pharmaceuticals | Phase 4 |
| Completed | Ultrasound-Assisted Lumbar Puncture in Children NCT03099642 | St. Justine's Hospital | N/A |
| Completed | Diagnostic Accuracy of a Host-response Based Diagnostic Tool for Distinguishing Between Bacterial and Viral Et NCT03052088 | MeMed Diagnostics Ltd. | — |
| Unknown | Fever Observational Study NCT03028818 | Intensive Care National Audit & Research Centre | — |
| Completed | Evaluation of Moderate to Severe Influenza Outcomes in Children NCT02979626 | University of Colorado, Denver | — |
| Recruiting | Antibiotic Prophylaxis in Patients Undergoing GVO NCT04140578 | Taipei Veterans General Hospital, Taiwan | Phase 4 |
| Completed | Testing the Effectiveness of a Modified Community Model in Improving Child Health Outcomes in Mashonaland East NCT03176914 | University of Zimbabwe | N/A |
| Terminated | Impact of Fever Prevention in Brain Injured Patients NCT02996266 | C. R. Bard | N/A |
| Completed | Obinutuzumab and Lenalidomide in Treating Patients With Previously Untreated Stage II-IV Grade 1-3a Follicular NCT02871219 | M.D. Anderson Cancer Center | Phase 2 |
| Completed | A Study of Ibuprofen 250 mg / Acetaminophen 500 mg Comparing The Antipyretic Effects in Healthy Male Volunteer NCT02761980 | Pfizer | Phase 3 |
| Unknown | Reduction of Intrapartum Fever With Intravenous Acetaminophen NCT02625454 | Richmond University Medical Center | Phase 2 |
| Completed | Evaluation of Infrared Cameras and Non-contact Infrared Thermometers for Measuring Body Temperatures NCT04370743 | Quanzeng Wang | — |
| Completed | Ear Temperature as Predictor of Rectal Temperature Measured With Modern Devices in the Emergency Department. NCT02977481 | University of Southern Denmark | — |
| Terminated | Measuring the Metabolic Cost of Fever NCT02939781 | Great Ormond Street Hospital for Children NHS Foundation Trust | — |
| Unknown | Thermographic Characteristics of Sore Throat by Thermographic Camera NCT01782183 | Doron Carmi | N/A |
| Completed | Asili Evaluation in the Democratic Republic of Congo NCT03536286 | Stanford University | N/A |
| Completed | Comparative Efficacy of Single-dose Doxycycline Versus Standard 5- Day Amoxicillin Treatment NCT03765931 | Institut de Recherche pour le Developpement | Phase 4 |
| Completed | The Impact of C-reactive Protein Testing NCT02758821 | University of Oxford | N/A |
| Completed | Personalised Risk Assessment in Febrile Illness to Optimise Real-life Management Across the European Union (PE NCT03502993 | Imperial College London | — |
| Completed | Fever and Febrile Support for Parents and Carers of Children 2016 NCT02903342 | University College Cork | N/A |
| Completed | SPOG 2015 FN Definition. A Multi-center Non-inferiority Trial on Safety of a High Versus Low Temperature Limit NCT02324231 | Swiss Pediatric Oncology Group | N/A |
| Completed | Procalcitonin (PCT) as a Diagnostic Marker of Bacterial Infection in the Patients Admitted for Fever and/or In NCT02898948 | Centre Hospitalier Universitaire, Amiens | — |
| Completed | Filter Paper Blood Spots Collected During Fever as a Source for Post-travel Diagnosis in Travelers NCT02900066 | Institute of Tropical Medicine, Belgium | — |
| Completed | Continous Monitoring of Vital Signs on Hospitalized Cancer Patients. NCT04299230 | Naestved Hospital | — |
| Completed | Ex Vivo-activated Autologous Lymph Node Lymphocytes in Treating Patients With Chronic Lymphocytic Leukemia NCT02530515 | M.D. Anderson Cancer Center | Phase 2 |
| Completed | Universal Versus Conditional Three-day Follow-up Visit for Children With Unclassified Fever NCT02926625 | Malaria Consortium | Phase 4 |
| Completed | Host-based Immunoassay for Differentiating Bacterial From Viral Infections (Post-marketing Study of ImmunoXper NCT03075111 | MeMed Diagnostics Ltd. | — |
| Completed | Validation of a Proteomic Signature and Assessment of Viremia in Children With Fever Without Source NCT03224026 | MeMed Diagnostics Ltd. | — |
| Completed | Non-inferiority Trial of Conditional vs Universal Follow up for Children With Fever in Democratic Republic of NCT02595827 | Johns Hopkins Bloomberg School of Public Health | Phase 3 |
| Completed | Observational Study to Assess Protection to Mumps in Children Received One-dose Mumps-containing Vaccine NCT02901990 | Jiangsu Province Centers for Disease Control and Prevention | — |
| Withdrawn | Preventive Oral Care NCT00800696 | Shaare Zedek Medical Center | N/A |
| Completed | Clinical Accuracy and Reliability of Infrared Tympanic Thermometer in an Adult Emergency Department NCT02937129 | The First Affiliated Hospital of Guangzhou Medical University | — |
| Completed | Innovative Public-private Partnership to Target Subsidized Antimalarials in the Retail Sector (Aim 2) NCT02461628 | Duke University | N/A |
| Completed | Time From Onset of Fever to Administration of Antibiotics in Neutropenic Fever Patients NCT03968328 | M.D. Anderson Cancer Center | — |
| Unknown | Short vs Prolonged Antibiotic Treatment for Hospitalized Hemato-oncology Patients With Febrile Neutropenia NCT02463747 | Tel-Aviv Sourasky Medical Center | Phase 4 |
| Terminated | Safety and Efficacy of Acetaminophen in the Intensive Care Unit. NCT02280239 | University of British Columbia | Phase 4 |
| Completed | Spirulina Supplementation and Infant Growth, Morbidity and Motor Development NCT03523182 | Programme Against Malnutrition | N/A |
| Completed | A New Formulation of Intravenous Paracetamol for Fever Management NCT02283203 | Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. | Phase 4 |
| Unknown | Prospective Comparative Study of the Efficacy of Common Antipyretic Treatments in Febrile Children NCT02294071 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Phase 4 |
| Completed | Fever and Wheezing Events in Children After US Influenza Vaccines Using Text Messaging NCT02295007 | Columbia University | N/A |
| Completed | The Effect of Prophylactic Antipyretics on Immune Responses and Fever After 2014-2015 and 2015-2016 Inactivate NCT02212990 | Duke University | N/A |
| Completed | IDIS Project Work Package 2: Establishing a Biobank at ITM and Collaborating Centres NCT02689193 | Institute of Tropical Medicine, Belgium | — |
| Completed | Innovative Public-private Partnership to Target Subsidized Antimalarials in the Retail Sector NCT02199977 | Duke University | N/A |
| Completed | Anticholinergic Premedication Induced Fever in Pediatric Ambulatory Anesthesia With Ketamine NCT02430272 | Inje University | N/A |
| Completed | Single-Dose Bioavailability Study of Two Formulations of Ibuprofen and Pseudoephedrine Hydrochloride Tablets NCT03429738 | Institut für Pharmakologie und Präventive Medizin | Phase 1 |
| Completed | Clinical Immunization Safety Assessment (CISA) Project: Pilot Study to Assess the Effect of Prophylactic Antip NCT01946594 | Duke University | Phase 4 |
| Completed | Effects of Intravenous Acetaminophen on Body Temperature and Hemodynamic Responses in Febrile Critically Ill A NCT01869699 | University of California, San Francisco | Phase 4 |
| Completed | A Retrospective, Blinded Validation of a Host-response Based Diagnostics NCT01911143 | MeMed Diagnostics Ltd. | — |
| Completed | Safety of Two Trivalent Influenza Vaccines Evaluated in Children and Adolescents 4 to 17 Years of Age NCT01857206 | Novartis Vaccines | Phase 3 |
| Completed | Assessing Fever Rates in Children Ages 24 to 59 Months After Live Attenuated Influenza Vaccine (LAIV) or Inact NCT01764269 | Columbia University | N/A |
| Completed | Phase 3 Study of Pelubiprofen & Loxoprofen in Patients With Upper Respiratory Tract Infection NCT01779271 | Daewon Pharmaceutical Co., Ltd. | Phase 3 |
| Terminated | Aggressive Fever Control With Intravenous Ibuprofen After Non-traumatic Brain Hemorrhage NCT01530880 | Columbia University | Phase 4 |
| Completed | Materno-fetal Consequences of Symptomatic Dengue in Pregnant Wowen in French Guiana NCT04989673 | Centre Hospitalier de Cayenne | — |
| Completed | Diagnostic Accuracy of Body Temperature Measurement in Geriatric Patients NCT01639430 | Klinikum Nürnberg | — |
| Completed | Hospital Admissions in Children Aged 3 Months to 5 Years Presenting With Fever to the Emergency Department NCT01196793 | Imperial College Healthcare NHS Trust | — |
| Completed | Assessment of the Effectiveness of New Clinical Guidelines for Differential Diagnosis and Management of Common NCT01681914 | Vanderbilt University | — |
| Completed | Trial Of Azithromycin In Campylobacter Concisus Patients With Diarrhea NCT01531218 | University of Aarhus | Phase 3 |
| Completed | Evaluation of Novel Antimicrobial Hand Towels NCT02512614 | Centers for Disease Control and Prevention | Phase 2 / Phase 3 |
| Completed | Biomarkers of Mortality and Morbidity in Children Hospitalized With Fever NCT04726826 | University of Alberta | — |
| Completed | Comparison of Temporal to Pulmonary Artery Temperature Measurement in Patients With Fever NCT01503294 | Massachusetts General Hospital | — |
| Terminated | Maternal Epidural Steroids and Hyperthemia NCT02212210 | Medical University of South Carolina | EARLY_Phase 1 |
| Completed | Cluster Randomised Trial of Malaria RDTs Used by CHWs in Afghanistan NCT01403350 | London School of Hygiene and Tropical Medicine | Phase 4 |
| Completed | FeverText: Assessing Fever Rates After Vaccination During the 2011-12 Influenza Season Using Text Messaging NCT01467934 | Columbia University | — |
| Completed | Surveillance Trial to Evaluate a Shortened Infusion Time of Intravenous Ibuprofen NCT01334944 | Cumberland Pharmaceuticals | Phase 4 |
| Completed | Etiology of Uncomplicated Fever in Children <5 in Rural Zanzibar NCT01094431 | Karolinska University Hospital | — |
| Unknown | VRI in Children With Acute Respiratory Symptoms. NCT01279863 | Rabin Medical Center | — |
| Terminated | Quantifying and Understanding the Signs and Symptoms of Fever NCT01287143 | National Institutes of Health Clinical Center (CC) | — |
| Completed | Clinical Evaluation of QFlu Combo Test NCT01506583 | Cellex, Inc. | — |
| Completed | Trial Comparing Low Dose and High Dose Steroids in Patients Undergoing Colorectal Surgery NCT01559675 | Cedars-Sinai Medical Center | N/A |
| Completed | Introducing Rapid Diagnostic Tests Into the Private Health Sector NCT01194557 | DBL -Institute for Health Research and Development | N/A |
| Completed | Prospective Surveillance of Febrile Illness for Dengue-Endemic Areas in Asia NCT01218906 | Sanofi | — |
| Completed | Anti-pyretic Therapy in Critically Ill Adults NCT01173367 | University of Calgary | Phase 2 |
| Completed | Study of Febrile Illness for Dengue-Endemic Areas in Latin America NCT01293331 | Sanofi | — |
| Suspended | Paracetamol Toxicity in Septic Patients NCT01182974 | Barzilai Medical Center | Phase 3 |
| Completed | Safety, Efficacy, and Pharmacokinetic Study of Intravenous Ibuprofen in Pediatric Patients NCT01002573 | Cumberland Pharmaceuticals | Phase 3 |
| Unknown | Cohort of Patients Infected by an Arbovirus NCT01099852 | University Hospital Center of Martinique | — |
| Completed | Safety and Immunogenicity Assessment of Rotavin-M1 in Vietnamese Children NCT01502969 | National Institute of Hygiene and Epidemiology, Vietnam | Phase 2 / Phase 3 |
| Completed | Effectiveness Of Rapid Diagnostic Tests in the New Context of Low Malaria Endemicity in Zanzibar NCT01002066 | Karolinska University Hospital | — |
| Completed | Reliability of Subjective Assessment of Fever by Parents and Health Care Providers in Children and Adolescents NCT01038219 | Meir Medical Center | — |
| Completed | Procalcitonin Levels in Patients With Fever and a Central Line NCT01175005 | Phoenix Children's Hospital | — |
| Completed | Pharmacokinetic Study to Compare Two Formulations of Paracetamol NCT01767428 | GlaxoSmithKline | Phase 1 |
| Completed | Role and Effectiveness of Rapid Diagnostic Tests in Home-based Management of Malaria NCT01048801 | DBL -Institute for Health Research and Development | N/A |
| Unknown | Vitamin D Zinc Fever NCT01080950 | Assaf-Harofeh Medical Center | — |
| Terminated | Efficacy of Diclofenac Potassium Versus Acetaminophen in Febrile Children With Acute Upper Respiratory Tract I NCT01019980 | Novartis Pharmaceuticals | Phase 4 |
| Completed | Lenalidomide and Ofatumumab in Treating Participants With Previously Treated Chronic Lymphocytic Leukemia or S NCT01002755 | M.D. Anderson Cancer Center | Phase 2 |
| Completed | The Antipyretic Efficacy of Oral and Intravenous Paracetamol and Intramuscular Diclofenac in Patients Presenti NCT01891435 | Hamad Medical Corporation | N/A |
| Completed | Paracetamol as Antipyretic and Analgesic Medication NCT01070732 | University of Athens | Phase 4 |
| Completed | PAVES: Pegfilgrastim Anti-vascular Endothelial Growth Factor (VEGF) Evaluation Study NCT00911170 | Amgen | Phase 3 |
| Terminated | A Study to Evaluate the Efficacy and Safety of IV Peramivir in Addition to Standard of Care Compared to Standa NCT00958776 | BioCryst Pharmaceuticals | Phase 3 |
| Completed | A Dose-escalating Study to Evaluate the Immunogenicity and Safety of Rotavin-M1 Vaccine in Healthy Infants NCT01377571 | National Institute of Hygiene and Epidemiology, Vietnam | Phase 2 |
| Completed | Pharmacokinetics, -Dynamics and Safety of Intravenous Paracetamol in Neonates NCT00969176 | Universitaire Ziekenhuizen KU Leuven | Phase 2 / Phase 3 |
| Completed | The Fever and Antipyretic in Critically Illness Evaluation Study NCT00940654 | Japanese Society of Intensive Care Medicine | — |
| Completed | Safety Study of a Rotavirus Vaccine (Rotavin-M1) Among Healthy Adults NCT01375907 | National Institute of Hygiene and Epidemiology, Vietnam | Phase 1 |
| Unknown | Ibuprofen Suppositories Administration in Infants and Children NCT00938509 | Soroka University Medical Center | Phase 4 |
| Completed | The Relationship of Defeverscence and Itraconazole Plasma Level Study in Immunocompromised Participants NCT01021683 | Janssen Korea, Ltd., Korea | — |
| Unknown | Diet and Lifestyle Intervention Study in Postpartum Women in China NCT01039051 | Huazhong University of Science and Technology | Phase 2 / Phase 3 |
| Completed | Treatment's Duration of Acute Uncomplicated Pyelonephritis NCT00873626 | Assistance Publique - Hôpitaux de Paris | Phase 4 |
| Completed | Examination of ACT Implementation in a Vivax / Falciparum Co-endemic Area NCT00935688 | London School of Hygiene and Tropical Medicine | Phase 4 |
| Withdrawn | Acetaminophen in Combination With N-Acetylcysteine (NAC) Versus Placebo in Treating Fever NCT01137591 | Columbia University | N/A |
| Completed | Temperature Control in Central Fever in the Neuro-ICU NCT00751634 | Northwestern University | Phase 4 |
| Completed | Effect of Race/Ethnicity and Genes on Acetaminophen Pharmacokinetics NCT00768716 | Tufts University | Phase 4 |
| Completed | Procalcitonin for Predicting Serious Bacterial Infection in Infants Less Than 3 Months NCT00800488 | Assistance Publique - Hôpitaux de Paris | — |
| Unknown | Oral Versus Rectal Ibuprofen for Fever in Young Children - a Randomized Control Study. NCT00729976 | Assaf-Harofeh Medical Center | Phase 4 |
| Completed | Observational Study Investigating the Response Rate of Itraconazole Injection in Treating Immunocompromised Pa NCT01060462 | Janssen Korea, Ltd., Korea | — |
| Completed | Impact of the PET in the Diagnosis Strategy of FUO or Inflammatory Syndrome in Immunocompetent Patients FUO-TE NCT01200771 | University Hospital, Limoges | N/A |
| Completed | The Impact of Antibiotic Prophylaxis on Incidence of Post-bronchoscopy Fever and Change of Serum Cytokines NCT01089218 | Seoul National University Hospital | Phase 4 |
| Completed | ACT for the Home Management in Malagasy Children NCT00612547 | National Malaria Control Programme, Madagascar | — |
| Completed | The Efficacy and Safety of Dexibuprofen Syrup NCT00812422 | Inje University | Phase 3 |
| Completed | Study of the Safety & Efficacy of Intravenous Acetaminophen in Pediatric Inpatients NCT00598702 | Mallinckrodt | Phase 3 |
| Completed | Study to Investigate the Causes of Fever in Children Living in Urban Dar es Salaam and Rural Ifakara NCT01812785 | Swiss Tropical & Public Health Institute | — |
| Completed | Safety and Efficacy of Intravenous Acetaminophen (IV APAP) in Adult Inpatients NCT00598559 | Mallinckrodt | Phase 3 |
| Completed | Training in Fever Case Management With Rapid Diagnostic Tests (RDTs) for Malaria in Uganda NCT00716599 | University of California, San Francisco | N/A |
| Terminated | A Study of Ceftobiprole in Patients With Fever and Neutropenia. NCT00529282 | Basilea Pharmaceutica | Phase 3 |
| Unknown | Urinary Catheter Exchange on Admission of Septic Elderly With Permanent Catheter Before Initiation of Antibiot NCT00503282 | Shaare Zedek Medical Center | — |
| Completed | Study of the Efficacy and Safety of Intravenous vs Oral Acetaminophen for Treatment of Fever in Healthy Adult NCT00564629 | Mallinckrodt | Phase 3 |
| Terminated | Acetaminophen for Fetal Tachycardia: a Randomized Pilot Trial NCT00377832 | Weill Medical College of Cornell University | N/A |
| Completed | Evaluation of 4 Artemisinin-based Combinations for Treating Uncomplicated Malaria in African Children NCT00393679 | Institute of Tropical Medicine, Belgium | Phase 3 |
| Completed | Safety of Intravenous Acetaminophen Vs Placebo for the Treatment of Endotoxin-Induced Fever in Healthy Adult M NCT00493311 | Mallinckrodt | Phase 3 |
| Completed | Safety and Pharmacokinetic (PK) Study of Intravenous (IV) Acetaminophen Administration in Pediatric Inpatients NCT00493246 | Mallinckrodt | Phase 1 |
| Withdrawn | A Study of Safety, Tolerability, and Pk of rhMBL in Pediatric Hematology/Oncology Pts With Fever and Neutropen NCT00520325 | Enzon Pharmaceuticals, Inc. | Phase 1 |
| Unknown | Ibuprofen Concentration in Cerebro Spinal Fluid (CSF) of Infants and Children NCT01099462 | Assaf-Harofeh Medical Center | — |
| Completed | Developing World Study for RotaTeq™ (V260-015)(COMPLETED) NCT00362648 | Merck Sharp & Dohme LLC | Phase 3 |
| Completed | Ibuprofen, Acetaminophen and Dipyrone to Fever Control in Children NCT01359020 | Mantecorp Industria Quimica e Farmaceutica Ltd. | Phase 4 |
| Completed | Pomegranate Products for Prevention of Common Cold NCT00617318 | Texas Heart Institute | Phase 3 |
| Terminated | Procalcitonin in Fever of Unknown Etiology NCT00398775 | Changi General Hospital | N/A |
| Completed | Daptomycin in Treating Neutropenia and Fever in Patients With Cancer NCT00335478 | OHSU Knight Cancer Institute | Phase 2 |
| Completed | Evaluation of Reproducibility of a Sporozoite Challenge Model for Plasmodium Vivax in Human Volunteers NCT00367380 | Malaria Vaccine and Drug Development Center | Phase 2 |
| Unknown | Orthostatic Hypotension in Children With Acute Febrile Illness NCT00452712 | Assaf-Harofeh Medical Center | — |
| Unknown | Parasite-based Diagnosis for Malaria in Uganda: Feasibility and Cost-Effectiveness NCT00565071 | Makerere University | N/A |
| Unknown | Evaluation of Fever Occurring in Labor in Patients Receiving Epidural Anesthesia NCT00326521 | MemorialCare | — |
| Completed | Paracetamol Oral Paediatric Suspension at 4.8% : Study of Acceptability and Safety. NCT00434681 | Sanofi | Phase 3 |
| Completed | Acetaminophen Before Vaccines for Infants Study (AVIS) NCT00325819 | Kaiser Permanente | Phase 3 |
| Withdrawn | Fever and Neutropenia in Pediatric Oncology Patients NCT03768869 | University of Colorado, Denver | Phase 3 |
| Completed | Ibuprofen Alone and in Combination With Acetaminophen for Treatment of Fever NCT00267293 | Penn State University | Phase 4 |
| Terminated | Acceptability and Cost Effectiveness of Home Based Management of Fever: Different Strategies NCT00259142 | DBL -Institute for Health Research and Development | N/A |
| Completed | Evaluation of Respiratory Specimens for Bacterial and Viral Pathogens by Real-Time PCR NCT00275691 | Mayo Clinic | — |
| Completed | A Study of Caldolor in Hospitalized Febrile Pediatric Patients NCT00225706 | Cumberland Pharmaceuticals | Phase 3 |
| Unknown | Adding a Second Drug for Febrile Children Treated With Acetaminophen NCT00389272 | Assaf-Harofeh Medical Center | N/A |
| Unknown | Procalcitonin in Diagnosing Bacteremia in the Emergency Department NCT00174122 | National Taiwan University Hospital | — |
| Completed | MK0991 Versus Amphotericin B for Empirical Therapy in Febrile, Neutropenic Pediatric Patients (0991-044) NCT00082537 | Merck Sharp & Dohme LLC | Phase 2 |
| Completed | Acetaminophen Concentration in Cerebrospinal Fluid in Infants NCT00389454 | Assaf-Harofeh Medical Center | — |
| Terminated | Low-risk Fever and Neutropenia in Children With Cancer: Safety and Efficacy of Oral Antibiotics in an Outpatie NCT00107081 | Swiss Pediatric Oncology Group | Phase 3 |
| Completed | Granulocyte Transfusions in Hematological Patients With Febrile Neutropenia NCT02544230 | Sorveglianza Epidemiologica Infezioni Fungine Emopatie Maligne | — |
| Completed | Placebo and Active Controlled Study to Compare the Antipyretic Efficacy of Aspirin® in Patients With Acute Feb NCT01464944 | Bayer | Phase 4 |
| Completed | Treatment of Fever Due to Malaria With Ibuprofen NCT00167713 | Albert Schweitzer Hospital | Phase 4 |
| Completed | Efficacy, Safety, and Pharmacokinetics of Intravenous Ibuprofen in Adult Febrile Patients NCT01131000 | Cumberland Pharmaceuticals | Phase 3 |
| Completed | Once-Daily Amikacin Plus Cloxacillin in Febrile Neutropenic Children NCT00129688 | Khon Kaen University | N/A |
| Completed | The Tobramycin Study NCT00257790 | Oslo University Hospital | Phase 4 |
| Completed | Phase I Study of the Safety, Tolerance, and Pharmacokinetics of FK463 in Immunocompromised Children With Fever NCT00001790 | National Cancer Institute (NCI) | Phase 1 |
| Recruiting | Familial Mediterranean Fever and Related Disorders: Genetics and Disease Characteristics NCT00001373 | National Human Genome Research Institute (NHGRI) | — |
| Completed | A Prospective, Randomized, Phase III Trial of FLAC (5-Fluorouracil, Leucovorin, Adriamycin, Cytoxan) Chemother NCT00001338 | National Cancer Institute (NCI) | Phase 3 |
| Completed | Same Day Dosing of Pegfilgrastim in Breast Cancer Patients Undergoing Chemotherapy (TAC) NCT00115414 | Amgen | Phase 2 |