NCT04363138

Link Between Eosinopenia and Bacterial Infections in the Elderly Subject Hospitalized in Geriatrics

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 156 (actual)
• Sponsor: Gérond'if · Academic / Other
• Sex: All
• Age: 75 Years
• Healthy volunteers: Not accepted

Summary

The main purpose of this monocentric, non-interventional, prospective study carried out in acute geriatrics (UGA) and post-rehabilitation care, is to determine if eosinopenia is associated with bacterial infections.

Detailed description

It's a monocentric, non-interventional, prospective study carried. At inclusion: Non-opposition will be collected by the investigator upon entering the Geriatric Unit. The investigators will have all the biological and radiological results and will decide whether or not to start antibiotic treatment. Patients will be divided into 2 groups: group with bacterial infections and the other with non-bacterial diseases. The patient's socio-demographic data, reason for hospitalization, history, BMI, state of dependence (ADL-IADL), MMSE, treatments will be collected. Biological examinations in the phase where an infection is not suspected will also be collected (NFS, ionogram, urea, creatinemia, albumin, pre albumin, CRP, hepatocellular workup. Clinical examination during the episode may be infectious as well that biological and radiological data will be collected as well as the diagnosis made. Antibiotic treatment is prescribed will be listed. The blood levels of eosinophils between the two groups will be compared. Follow-up at 1 month: The effectiveness of antibiotics will be evaluated on the absence of inflammatory syndrome and fever after the recommended antibiotic treatment and the duration of the recommended treatment. Vital status will be collected.

Conditions

• Fever
• Leukocytes
• C Reactive Protein (CRP) is Less Than 20 mg/ l

Timeline

• Start date: 2021-07-02
• Primary completion: 2021-08-01
• Completion: 2022-08-01
• First posted: 2020-04-27
• Last updated: 2023-01-12

Locations

1 site across 1 country: France