Clinical Trials Directory

Trials / Sponsors / Amgen

Amgen

Industry · 1,027 registered clinical trials59 currently recruiting.

StatusTrialPhaseStarted
Not Yet RecruitingA Study Evaluating Subcutaneous Versus Intravenous Blinatumomab in Newly Diagnosed Adults With B-cell Precurso
Philadelphia Chromosome Negative B-cell Precursor Acute Lymphoblastic Leukemia
Phase 32026-06-11
Not Yet RecruitingTrial of Xaluritamig in Adults With Metastatic Castration-resistant Prostate Cancer
Metastatic Castration-resistant Prostate Cancer (mCRPC)
Phase 12026-05-26
Not Yet RecruitingStudy of Tarlatamab + ZL-1310 +/- Anti-programmed Death Ligand 1 (Anti-PD-L1) in Small Cell Lung Cancer (SCLC)
Small Cell Lung Cancer
Phase 12026-05-05
RecruitingA Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Inebilizumab in Childre
Generalized Myasthenia Gravis
Phase 22026-04-30
RecruitingObservational Safety Study in Women With Neuromyelitis Optica Spectrum Disorder (NMOSD) Exposed to UPLIZNA® Du
Neuromyelitis Optica Spectrum Disorder, Pregnancy Related
2026-04-15
Not Yet RecruitingAn Open-label, Rollover Trial to Evaluate the Efficacy and Safety of AMG 732 in Participants With Thyroid Eye
Thyroid Eye Disease
Phase 22026-04-14
Not Yet RecruitingEffect of Maridebart Cafraglutide on How Oral Contraceptives Are Absorbed and Processed in the Body in Postmen
Overweight, Obesity
Phase 12026-04-09
RecruitingEvaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS)
Ewing Sarcoma
Phase 12026-04-08
Not Yet RecruitingStudy to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Inebilizumab in Pediatri
Immunoglobulin G4-related Disease
Phase 22026-04-03
RecruitingAMG 436 as Monotherapy and Combination Therapy in Participants With MSI-H/dMMR Solid Tumors
Metastatic or Locally Advanced Solid Tumors With Microsatellite Instability-high (MSI-H) or Mismatched Repair Deficiency (dMMR)
Phase 12026-03-23
RecruitingOlpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary Computed Tomography Angiogra
Cardiovascular Disease
Phase 32026-03-23
RecruitingPediatric Safety Follow-up Study of Prior Treatment With Romosozumab for Osteogenesis Imperfecta
Osteogenesis Imperfecta
Phase 32026-03-18
RecruitingA Trial to Evaluate Efficacy and Safety of Maridebart Cafraglutide in Adults Living With Elevated Liver Fat an
Overweight or Obesity and Elevated Liver Fat
Phase 22026-03-05
RecruitingA Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Peglo
Uncontrolled Gout
Phase 32026-02-09
RecruitingComparing the Extent to Which Two Evolocumab Drug Products Are Made Available in the Body After a Single Subcu
Healthy Participants, Pharmacokinetics
Phase 12026-01-16
RecruitingA Rollover Study Evaluating Sotorasib With or Without Panitumumab in Participants With KRAS p.G12C Mutation
Advanced Solid Tumors
Phase 22026-01-02
RecruitingMaridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway P
Obesity, Obstructive Sleep Apnea
Phase 32025-12-19
Active Not RecruitingA Trial to Compare the Extent to Which Maridebart Cafraglutide (AMG 133) is Made Available in the Body When Ad
Overweight and Obesity
Phase 12025-12-15
RecruitingA Study of Subcutaneous Blinatumomab in Children With R/R and and MRD+ B-Cell Precursor Acute Lymphoblastic Le
Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia, Minimal Residual Disease + B-Cell Acute Lymphoblastic Leukemia
Phase 1 / Phase 22025-12-08
RecruitingA Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve M
Metastatic Castration-resistant Prostate Cancer
Phase 32025-11-28
RecruitingMaridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airw
Obstructive Sleep Apnea
Phase 32025-11-25
Active Not RecruitingEffect of Maridebart Cafraglutide on the Heart's Electrical Activity
Overweight, Obesity
Phase 12025-10-22
Active Not RecruitingComparing the Extent to Which Maridebart Cafraglutide (AMG 133) is Made Available in the Body When Administere
Overweight, Obesity
Phase 12025-10-10
RecruitingStudy Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor P
Metastatic Hormone-sensitive Prostate Cancer (mHSPC)
Phase 12025-10-07
RecruitingA Study of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (D
Extensive Stage Small Cell Lung Cancer
Phase 12025-09-16
CompletedA Study to Evaluate Pharmacokinetics, Safety, and Tolerability of Teprotumumab (AMG 632) Administered Intraven
Healthy Volunteers
Phase 12025-08-26
RecruitingOCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Ma
Cardiovascular Disease
Phase 32025-08-22
RecruitingA Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etopo
Small-cell Lung Cancer, Extensive Stage Small-cell Lung Cancer
Phase 32025-08-18
CompletedReal World Evaluation of Sotorasib Among Chinese Non-Small Cell Lung Cancer Patients
Non-Small Cell Lung Cancer
2025-08-11
RecruitingA Study to Evaluate the Effect of Maridebart Cafraglutide on Insulin Sensitivity and β-cell Function in Partic
Type 2 Diabetes Mellitus
Phase 12025-08-05
RecruitingAMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic So
KRAS Altered Advanced or Metastatic Solid Tumors
Phase 12025-07-31
RecruitingEvaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerot
Atherosclerotic Cardiovascular Disease, Overweight, Obesity
Phase 32025-07-25
RecruitingA Phase 2 Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases
Systemic Lupus Erythematosus, Active Refractory Rheumatoid Arthritis
Phase 22025-07-16
CompletedReal World Study to Describe the Effectiveness and Safety of Teprotumumab Among Thyroid Eye Disease Patients
Thyroid Eye Disease
2025-07-02
RecruitingMaridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Heart Failure With Preserved Ejection Fraction, Heart Failure With Mildly Reduced Ejection Fraction, Obesity
Phase 32025-06-25
Active Not RecruitingEfficacy and Safety of Maridebart Cafraglutide in Adult Participants in Japan Who Have Obesity Disease
Obesity Disease
Phase 32025-06-13
RecruitingA Study for the Evaluation of Efficacy and Safety of Prolia® in Participants With Glucocorticoid-induced Osteo
Glucocorticoid-induced Osteoporosis
Phase 42025-05-24
RecruitingStudy of Tarlatamab in Combination With YL201 With or Without Anti-programmed Death Ligand 1 (PD-L1) in Partic
Small Cell Lung Cancer
Phase 12025-05-16
CompletedThe Effect of AMG 133 on Gastric Emptying
Overweight or Obesity
Phase 12025-04-17
TerminatedSingle and Multiple Ascending Dose Study of AMG 378 in Healthy Participants
Healthy Volunteers
Phase 12025-04-08
Active Not RecruitingEfficacy and Safety of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus Who Have Ob
Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight
Phase 32025-03-17
CompletedA Study to Evaluate AMG 133 in Participants With Varying Degrees of Hepatic Impairment or Normal Hepatic Funct
Hepatic Impairment
Phase 12025-03-14
Active Not RecruitingEvaluation of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mellitus Who Have Obesity
Obesity
Phase 32025-03-12
CompletedA Trial to Assess the Effect of Kidney Impairment on How AMG 133 is Absorbed, Broken Down, and Eliminated by t
Overweight and Obesity
Phase 12025-03-11
Active Not RecruitingA Phase 2, Open-label, Randomized, Multicenter Study of Tarlatamab Dosing Regimens in Subjects With SCLC
Small Cell Lung Cancer (SCLC)
Phase 22025-02-26
RecruitingA Long-term Extension Study of Dazodalibep in Participants With Sjögren's Syndrome (SS)
Sjögren's Syndrome
Phase 32025-02-25
RecruitingComparison Between ABP 692 and Ocrevus® (Ocrelizumab)
Relapsing-remitting Multiple Sclerosis (RRMS)
Phase 32025-01-13
CompletedStudy to Investigate Intravenous Blinatumomab in Japanese Adult Participants With Newly Diagnosed Philadelphia
B-precursor Acute Lymphoblastic Leukemia
Phase 12025-01-08
RecruitingA Phase 2 Study of Anvumetostat in Participants With MTAP-deleted Advanced NSCLC (MTAPESTRY 201)
MTAP-deleted NSCLC
Phase 22024-12-26
CompletedA Trial to Evaluate Interactions Between Antiemetic Medication and AMG 133 in Participants Living With Overwei
Overweight, Obesity
Phase 12024-12-10
RecruitingPhase 3 Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Participants With
Metastatic Castration-resistant Prostate Cancer
Phase 32024-12-09
RecruitingEvaluation of Neoadjuvant Xaluritamig in Localized Prostate Cancer
Prostate Cancer
Phase 12024-11-25
CompletedA Study to Determine the Feasibility of Online Recruitment of People Using an Anti-Obesity Medication for Weig
Obesity
2024-11-14
Active Not RecruitingA Study of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus (T2DM)
Type 2 Diabetes Mellitus (T2DM)
Phase 22024-11-07
RecruitingStudy to Evaluate Avacopan in Combination With a Rituximab or Cyclophosphamide-containing Regimen, in Children
Vasculitis
Phase 32024-10-22
RecruitingA Phase 1, Randomized, Double-blind, Placebo-controlled Study Evaluating AMG 691 in Healthy Participants and P
Asthma
Phase 12024-10-16
RecruitingSubcutaneous Tarlatamab in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-308)
Extensive Stage Small Cell Lung Cancer
Phase 12024-10-07
Active Not RecruitingEvaluation of Xaluritamig in High-Risk, Biochemically Recurrent, Non-metastatic Castrate-sensitive Prostate Ca
Prostate Cancer, High-risk Biochemical Recurrence, High Risk Biochemical Recurrence of Non-metastatic Castration-sensitive Prostate Cancer
Phase 12024-09-23
RecruitingAnvumetostat Alone or in Combination With Other Therapies in Subjects With Advanced Thoracic Tumors With Homoz
Thoracic Tumors, Non-small Cell Lung Cancer
Phase 12024-09-17
CompletedA Study to Assess the Effect of Olpasiran on QT/QTc Intervals in Healthy Participants
Basic Science
Phase 12024-09-12
Active Not RecruitingPharmacokinetic Similarity Between ABP 234 and Keytruda® (Pembrolizumab)
Early-stage Non-squamous Non-small Cell Lung Cancer (NSCLC)
Phase 32024-09-12
RecruitingSingle and Multiple Ascending Dose Study of AMG 513 in Participants With Obesity
Cardiometabolic Disease
Phase 12024-09-09
Active Not RecruitingA Study to Compare ABP 234 and Keytruda® (Pembrolizumab) in Participants With Advanced or Metastatic Non-squam
Advanced or Metastatic Non-squamous Non-Small Cell Lung Cancer
Phase 32024-09-09
Active Not RecruitingStudy Evaluating Tarlatamab in Chinese Participants With Advanced Small Cell Lung Cancer After Two or More Pri
Extensive Stage Small Cell Lung Cancer
Phase 22024-08-27
CompletedA Study to Evaluate AMG 133 Administered Subcutaneously in Participants With Overweight or Obesity
Overweight, Obesity
Phase 12024-08-20
Active Not RecruitingEvaluation of Efficacy and Safety of Prolia in Subjects of Male Osteoporosis in Mainland China
Osteoporosis
Phase 42024-08-06
CompletedA Study to Evaluate Bioavailability of Rocatinlimab Autoinjector and Vial in Healthy Participants
Atopic Dermatitis
Phase 12024-08-06
Active Not RecruitingStudy of Blinatumomab Administration in Chinese Pediatric Participants With Relapsed/Refractory B Precursor Ac
B Precursor Acute Lymphoblastic Leukemia, Relapsed/Refractory B Precursor Acute Lymphoblastic Leukemia
Phase 22024-07-23
Active Not RecruitingA Phase 3, Placebo-controlled, Double-blind Study Assessing Rocatinlimab in Prurigo Nodularis
Prurigo Nodularis
Phase 32024-07-18
RecruitingStudy of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve
Metastatic Colorectal Cancer
Phase 32024-07-17
WithdrawnA Clinical Trial to Evaluate Bioavailability and Effect of Food for Sotorasib in Healthy Participants
Healthy Participants
Phase 12024-07-15
Active Not RecruitingA Trial to Investigate Teprotumumab Subcutaneous Administration Compared With Placebo in Male and Female Adult
Thyroid Eye Disease
Phase 32024-07-05
CompletedA Study of Avacopan in Participants With Normal Renal Function and Participants With End-Stage Renal Disease (
End-Stage Renal Disease (ESRD)
Phase 12024-06-18
Active Not RecruitingStudy Comparing Tarlatamab and Durvalumab Versus Durvalumab Alone in First-Line Extensive-Stage Small-Cell Lun
Extensive-Stage Small-Cell Lung Cancer, Small-Cell Lung Cancer
Phase 32024-06-05
RecruitingA Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease
Thyroid Eye Disease
Phase 1 / Phase 22024-05-30
RecruitingA Study Evaluating Anvumetostat in Combination With Other Therapies in Participants With Advanced Gastrointest
Advanced Gastrointestinal, Biliary Tract, and Pancreatic Cancers
Phase 12024-05-29
Active Not RecruitingA Phase 2, Dose Ranging Study Assessing Rocatinlimab in Moderate-to-severe Asthma
Asthma
Phase 22024-05-24
Active Not RecruitingA Phase 2 Study to Investigate Efficacy and Safety of HZN-1116 in Participants With Sjogren's Syndrome
Sjogren's Syndrome
Phase 22024-05-09
CompletedA Study to Evaluate AMG 133 in Chinese Participants With Obesity or Overweight
Obesity
Phase 12024-04-25
RecruitingStudy to Evaluate Efficacy and Safety of Romosozumab Compared With Bisphosphonates in Children and Adolescents
Osteogenesis Imperfecta
Phase 32024-04-22
Active Not RecruitingA Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Sever
Sjögren's Syndrome (SS)
Phase 32024-04-08
CompletedA Study With Self-administered Rocatinlimab in Adolescent and Adult Participants With Moderate-to-severe Atopi
Atopic Dermatitis
Phase 32024-04-02
Active Not RecruitingLong-term, Open-label, Safety Study of Inebilizumab in Neuromyelitis Optica Spectrum Disorder (NMOSD)
Neuromyelitis Optica Spectrum Disorder
Phase 42024-04-02
CompletedA Trial to Investigate the Non-inferiority of Pegloticase Administered Every 4 Weeks (Q4W) With MTX Compared W
Gout
Phase 42024-03-18
Active Not RecruitingA Study of AMG 355 Alone and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors
Advanced Solid Tumors
Phase 12024-03-07
RecruitingStudy Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer (LS-SCLC)
Limited Stage Small Cell Lung Cancer, Small Cell Lung Cancer
Phase 32024-02-20
CompletedA Study to Assess Bioavailability of Rocatinlimab (AMG 451) Vial and Prefilled Syringe in Healthy Participants
Atopic Dermatitis
Phase 12024-02-15
RecruitingA Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis
Antineutrophil Cytoplasmic Antibody-associated Vasculitis
Phase 42024-02-07
Active Not RecruitingA Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With M
Sjogren's Syndrome
Phase 32024-01-24
CompletedA Study to Evaluate Rocatinlimab (AMG 451) in Healthy Chinese Participants
Atopic Dermatitis
Phase 12024-01-23
CompletedA Phase 2 Proof of Concept Study to Evaluate the Efficacy and Safety of Daxdilimab in Participants With Dermat
Idiopathic Inflammatory Myositis
Phase 22023-12-04
CompletedA Study to Investigate Efficacy and Safety of Apremilast 30 mg Twice Daily (BID) in Chinese Participants With
Plaque Psoriasis
Phase 32023-11-27
RecruitingA Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as
Non-Small Cell Lung Cancer (NSCLC)
Phase 32023-11-16
Active Not RecruitingA Study to Evaluate ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Unresectable or Metastatic Mela
Melanoma
Phase 32023-11-02
CompletedA Study of Romosozumab (EVENITY®) in Postmenopausal Women in India With Osteoporosis at a High Risk of Fractur
Postmenopausal Osteoporosis
Phase 42023-10-30
Active Not RecruitingA Study of Apremilast in Pediatric Participants in Children With Mild to Moderate Plaque Psoriasis
Plaque Psoriasis
Phase 32023-10-24
WithdrawnEfficacy of Romiplostim in Treatment of SAA in Adults Previously Untreated With or Refractory to Immunosuppres
Severe Aplastic Anemia (SAA)
Phase 22023-08-31
WithdrawnA Study of Subcutaneous (SC) AMG 701 in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
Relapsed/Refractory Multiple Myeloma
Phase 12023-08-29
Active Not RecruitingStudy of XGEVA® (Denosumab) in Chinese Adults and Skeletally Mature Adolescents With Giant Cell Tumor of the B
Giant Cell Tumor of Bone
Phase 42023-08-17
Active Not RecruitingA Phase 1/2 Study of Anvumetostat in Combination With IDE397 in Participants With Advanced Methylthioadenosine
MTAP-null Non-Small-Cell Lung Cancer, MTAP-null Solid Tumors
Phase 1 / Phase 22023-08-01
CompletedA Study to Evaluate Similarity of ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Resected Melanoma
Melanoma
Phase 32023-07-26
RecruitingStudy of Inebilizumab in Pediatric Subjects With Neuromyelitis Optica Spectrum Disorder
Neuromyelitis Optica Spectrum Disorder
Phase 22023-07-03
CompletedStudy to Explore the Safety, Tolerability, and Pharmacokinetics of AMG 305 in Subjects With Advanced Solid Tum
Advanced Solid Tumors
Phase 12023-06-13
CompletedA Study Assessing Rocatinlimab on Vaccine Antibody Response in Moderate-to-severe Atopic Dermatitis (AD) (ROCK
Atopic Dermatitis, Moderate-to-severe Atopic Dermatitis
Phase 32023-06-07
CompletedStudy to Investigate the Effect of Rocatinlimab (AMG 451) on the Pharmacokinetics of Multiple Cytochrome P450
Atopic Dermatitis
EARLY_Phase 12023-06-03
Active Not RecruitingA Study to Assess Long-term Safety, Tolerability, and Efficacy of Rocatinlimab in Adult and Adolescent Partici
Atopic Dermatitis
Phase 32023-05-31
Active Not RecruitingStudy Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung Cancer
Small Cell Lung Cancer (SCLC)
Phase 32023-05-31
TerminatedLong-term Safety and Efficacy of Efavaleukin Alfa in Participants With Moderately to Severely Active Ulcerativ
Ulcerative Colitis
Phase 22023-04-28
TerminatedStudy of Daxdilimab (HZN-7734) in Participants With Active Proliferative Lupus Nephritis (LN)
Lupus Nephritis
Phase 22023-04-26
CompletedA Study to Evaluate Rocatinlimab (AMG 451) in Adolescent Participants With Moderate-to-severe Atopic Dermatiti
Atopic Dermatitis
Phase 32023-04-20
CompletedA Trial to Investigate Teprotumumab (High-concentration Formulation) Subcutaneous Administration in Healthy Ad
Healthy Volunteers
Phase 12023-03-24
RecruitingA Study of Apremilast in Children With Oral Ulcers Associated With Behçet's Disease or Juvenile Psoriatic Arth
Behçet's Disease, Juvenile Psoriatic Arthritis
Phase 32023-03-23
WithdrawnStudy Evaluating the Safety, Tolerability, and Efficacy of FLT3 CAR-T AMG 553 in FLT3-positive Relapsed/Refrac
Relapsed/Refractory Acute Myeloid Leukemia
Phase 12023-03-13
TerminatedA Phase 1 Safety, Tolerability, and Pharmacokinetics Study of AMG 794 With Claudin 6-positive Non-small Cell L
Non-squamous Non-small Cell Lung Cancer, Epithelial Ovarian Cancer, Claudin 6-positive Advanced/Metastatic Malignant Solid Tumors
Phase 12023-02-28
CompletedA Study Assessing Rocatinlimab in Combination With Topical Corticosteroid and/or Topical Calcineurin Inhibitor
Atopic Dermatitis
Phase 32023-02-21
CompletedA Study to Assess the Safety, Tolerability, and Efficacy of Rocatinlimab in Adolescent Participants With Moder
Atopic Dermatitis
Phase 32023-01-30
Active Not RecruitingA Study to Assess the Efficacy and Safety of Apremilast in Japanese Pediatric Participants With Moderate to Se
Plaque Psoriasis
Phase 32023-01-25
CompletedA Study to Evaluate ABP 938 and Aflibercept (Eylea®) in Participants With Chorioretinal Vascular Disease (CVD)
Chorioretinal Vascular Disease
Phase 32023-01-23
CompletedDose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of AMG 133 in Adult Subjects With Overwe
Obesity, Overweight, Type 2 Diabetes Mellitus
Phase 22023-01-18
TerminatedStudy of Daxdilimab (HZN-7734) in Participants With Moderate-to-Severe Primary Discoid Lupus Erythematosus
Discoid Lupus Erythematosus
Phase 22022-12-29
RecruitingA Study Assessing Repatha® in Combination With Standard of Care (SOC) Compared With SOC on Major Cardiovascula
Major Cardiovascular Event, Established Atherosclerotic Cardiovascular Disease
2022-12-19
CompletedA Study Assessing Rocatinlimab (AMG 451) Monotherapy in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-Hori
Atopic Dermatitis
Phase 32022-12-14
Active Not RecruitingOlpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction (OCEAN(a)) - Outcomes Trial
Atherosclerotic Cardiovascular Disease
Phase 32022-12-14
TerminatedAMG 176 With Azacitidine in Subjects With Myelodysplastic Syndrome /Chronic Myelomonocytic Leukemia
Higher Risk Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia
Phase 12022-11-14
TerminatedAn Open-label Extension Trial of HZNP-HZN-825-301 in Adult Participants With Diffuse Cutaneous Systemic Sclero
Diffuse Cutaneous Systemic Sclerosis, Sclerosis, Systemic
Phase 22022-11-04
Active Not RecruitingEVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction
Cardiovascular Disease, Myocardial Infarction, Stroke
Phase 42022-10-26
CompletedA Study Evaluating Bemarituzumab in Solid Tumors With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpres
Solid Tumors
Phase 1 / Phase 22022-09-23
CompletedA Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of Olpasiran in Participants With Vario
Hepatic Impairment
Phase 12022-09-13
CompletedA Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of Olpasiran in Participants With Norma
Renal Impairment
Phase 12022-09-13
Active Not RecruitingFirst-Line Tarlatamab in Combination With Carboplatin, Etoposide, and PD-L1 Inhibitor in Subjects With Extensi
Extensive Stage Small Cell Lung Cancer
Phase 12022-08-24
CompletedSingle and Multiple Ascending Dose Study to Evaluate AMG 786 in Healthy Participants and Participants With Obe
Obesity
Phase 12022-07-26
CompletedA Study to Evaluate the Impact of Omeprazole on the Pharmacokinetics of Sotorasib Co-administered With an Acid
Healthy Volunteers
Phase 12022-07-14
CompletedA Study of TEPEZZA® Treatment in Participants With Thyroid Eye Disease
Thyroid Eye Disease
Phase 12022-07-14
CompletedEffect of Repeated Oral Doses of Avacopan on the Pharmacokinetics (PK) of a Single Dose of Simvastatin
Healthy Volunteers
Phase 12022-06-28
TerminatedStudy of Daxdilimab (HZN-7734) for the Treatment of Systemic Lupus Erythematosus in an Open-label Extension St
Systemic Lupus Erythematosus
Phase 22022-06-01
CompletedA Study Evaluating Rocatinlimab in Moderate-to-severe Atopic Dermatitis (ROCKET-IGNITE)
Atopic Dermatitis
Phase 32022-05-31
Active Not RecruitingA Study Evaluating Bemarituzumab in Combination With Other Anti-cancer Therapies in Subjects With Previously U
Gastric Cancer, Gastroesophageal Junction Cancer
Phase 1 / Phase 22022-05-17
CompletedStudy of DAXDILIMAB for the Treatment of Moderate-to-Severe Alopecia Areata
Alopecia Areata
Phase 22022-04-27
Active Not RecruitingSotorasib and Panitumumab Versus Investigator's Choice for Participants With Kirsten Rat Sarcoma (KRAS) p.G12C
Colorectal Cancer (CRC)
Phase 32022-04-19
CompletedA Cross-sectional Study of Lipoprotein(a) Levels in Patients With Documented History of Atherosclerotic Cardio
Atherosclerotic Cardiovascular Disease
N/A2022-04-19
TerminatedA Study of Bemarituzumab Monotherapy and Combination With Other Anti-cancer Therapy in SqNSCLC With FGFR2b Ove
Squamous-Cell Non-Small-Cell Lung Cancer
Phase 12022-03-29
CompletedA Study in Healthy Volunteers to Compare the Pharmacokinetics of Sotorasib Administered as 1 or 2 Tablets
Healthy Participants
Phase 12022-03-21
RecruitingApremilast Pediatric Study in Children With Active Juvenile Psoriatic Arthritis
Active Juvenile Psoriatic Arthritis
Phase 32022-03-17
Active Not RecruitingBemarituzumab Plus Chemotherapy and Nivolumab Versus Chemotherapy and Nivolumab for FGFR2b Overexpressed Untre
Gastric Cancer, Gastroesophageal Junction Adenocarcinoma
Phase 32022-03-14
CompletedPhase 3, Randomized Study of Apremilast in Japanese Participants With Palmoplantar Pustulosis (PPP)
Palmoplantar Pustulosis
Phase 32022-03-08
Active Not RecruitingBemarituzumab or Placebo Plus Chemotherapy in Gastric Cancers With Fibroblast Growth Factor Receptor 2b (FGFR2
Gastric Cancer, Gastroesophageal Junction Adenocarcinoma
Phase 32022-03-07
Active Not RecruitingA Study of Anvumetostat in Participants With Advanced MTAP-null Solid Tumors (MTAPESTRY 101)
Advanced MTAP-null Solid Tumors
Phase 1 / Phase 22022-02-01
TerminatedSafety and Efficacy of Efavaleukin Alfa in Participants With Moderately to Severely Active Ulcerative Colitis
Ulcerative Colitis
Phase 22022-01-31
CompletedA Study of Sotorasib (AMG 510) in Participants With Stage IV NSCLC Whose Tumors Harbor a KRAS p.G12C Mutation
Non-small Cell Lung Cancer
Phase 22022-01-28
TerminatedA Multicenter Trial to Evaluate the Efficacy, Safety and Tolerability of HZN-825 in Subjects With Idiopathic P
Idiopathic Pulmonary Fibrosis
Phase 22022-01-20
Active Not RecruitingA Phase 2 Study of Tarlatamab in Patients With Small Cell Lung Cancer (SCLC)
Relapsed/Refractory Small Cell Lung Cancer
Phase 22021-12-01
TerminatedA Study With TEPEZZA in Patients With Diffuse Cutaneous Systemic Sclerosis (dcSSc)
Diffuse Cutaneous Systemic Sclerosis
Phase 12021-11-17
TerminatedA Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients
Diffuse Cutaneous Systemic Sclerosis, Sclerosis, Systemic
Phase 22021-11-05
RecruitingStudy Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy
Newly Diagnosed Philadelphia (Ph)-Negative B-cell Precursor Acute Lymphoblastic Leukemia (ALL)
Phase 32021-11-02
CompletedA Comparative Study Between ABP 501 and Humira® in Participants With Moderate to Severe Plaque Psoriasis
Plaque Psoriasis
Phase 32021-10-04
CompletedAMG 757 and AMG 404 in Subjects With Small Cell Lung Cancer (SCLC)
Small Cell Lung Cancer
Phase 12021-09-27
CompletedTEPEZZA® (Teprotumumab-trbw) Post-Marketing Requirement Study
Thyroid Eye Disease
Phase 42021-09-16
CompletedStudy of AMG 133 Administered Subcutaneously in Healthy Japanese and Caucasian Participants
Healthy Participants
Phase 12021-09-10
RecruitingApremilast Pediatric Study in Children With Active Oral Ulcers Associated With Behçet's Disease
Behçet Disease
Phase 32021-09-09
CompletedA Study Evaluating TEPEZZA® Treatment in Patients With Chronic (Inactive) Thyroid Eye Disease
Thyroid Eye Disease, Chronic (Inactive) Thyroid Eye Disease
Phase 42021-09-02
TerminatedStudy of AMG 160 in Subjects With Non-Small Cell Lung Cancer
Non-small Cell Lung Cancer, NSCLC
Phase 12021-08-31
TerminatedFeasibility Study to Evaluate Outpatient Blinatumomab in Subjects With Minimal Residual Disease (MRD) of B-pre
B-precursor Acute Lymphoblastic Leukemia
Phase 42021-08-26
CompletedEffect of Coadministration of Sotorasib on the Pharmacokinetics of Rosuvastatin in Healthy Participants
Healthy Participants
Phase 12021-08-20
CompletedA Study to Compare the Pharmacokinetics of Two Different Tablets of Sotorasib in Healthy Participants
Healthy Participants
Phase 12021-08-16
CompletedStudy of Efavaleukin Alfa in Healthy Chinese, Japanese, and Caucasian Participants
Inflammatory Diseases
Phase 12021-08-09
CompletedA Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Olpasiran in Chinese Pa
Elevated Serum Lipoprotein(a)
Phase 12021-07-28
CompletedA Study Comparing the Pharmacokinetics (PK) of ABP 501 40 mg/0.4 mL (ABP 501-HCF) and ABP 501 40 mg/0.8 ml (AB
Adalimumab
Phase 12021-07-23
CompletedA Study of Single and Multiple Ascending Doses of VIB1116 in Rheumatic Diseases
Dendritic Cell -Mediated Rheumatic Diseases
Phase 12021-07-06
CompletedA Study to Evaluate Treatment Satisfaction With Erenumab in Participants With Migraine
Migraine
Phase 42021-06-11
CompletedA Study of AMG 757 in Participants With Neuroendocrine Prostate Cancer
Neuroendocrine Prostate Cancer
Phase 12021-06-10
CompletedStudy of VIB7734 for the Treatment of Moderate to Severely Active SLE
Lupus Erythematosus, Systemic
Phase 22021-05-28
CompletedSingle Ascending Dose of AMG 609 in Participants With Non-alcoholic Fatty Liver Disease
Non-alcoholic Fatty Liver Disease
Phase 12021-05-24
WithdrawnA Study of ABP 215 Versus Bevacizumab in Chinese Subjects With Advanced Non-Squamous Non-Small Cell Lung Cance
Metastatic Non-small Cell Lung Cancer (NSCLC), Non-squamous NSCLC
Phase 32021-05-15
TerminatedEfficacy and Safety of Efavaleukin Alfa in Subjects With Active Systemic Lupus Erythematosus
Active Systemic Lupus Erythematosus
Phase 22021-05-06
TerminatedA Study of AMG 340 in Subjects With Metastatic Castrate-Resistant Prostate Carcinoma
Metastatic Castration-resistant Prostate Cancer
Phase 12021-04-29
CompletedStudy of AMG 994 Monotherapy and AMG 994 and AMG 404 Combination Therapy in Participants With Advanced Solid T
Advanced Solid Tumors
Phase 12021-04-29
CompletedPharmacokinetics of Sotorasib in Healthy Participants and Participants With Moderate or Severe Hepatic Impairm
Hepatic Impairment
Phase 12021-04-22
CompletedStudy to Evaluate Tezepelumab in Adults With Chronic Spontaneous Urticaria
Chronic Spontaneous Urticaria
Phase 22021-04-15
CompletedA Study to Investigate Interchangeability of ABP 654 for the Treatment of Participants With Moderate to Severe
Psoriasis
Phase 32021-03-24
CompletedPegloticase and Methotrexate Co-administered in Participants With Uncontrolled Gout Who Previously Failed Pegl
Uncontrolled Gout
Phase 42021-03-08
RecruitingAimovig Pregnancy Exposure Registry
Migraine
2021-01-27
CompletedA Phase 4, Open-label Study of KRYSTEXXA® (Pegloticase) Co-administered With Methotrexate (MTX) in Patients Wi
Uncontrolled Gout, Chronic Gout
Phase 42021-01-26
CompletedStudy to Evaluate Romosozumab in Children and Adolescents With Osteogenesis Imperfecta
Osteogenesis Imperfecta
Phase 12021-01-21
TerminatedSafety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (mCRPC)
Metastatic Castration-resistant Prostate Cancer
Phase 1 / Phase 22021-01-15
RecruitingA Study of Subcutaneous Blinatumomab Administration in Participants With R/R and MRD+ B-ALL
B Cell Precursor Acute Lymphoblastic Leukemia
Phase 1 / Phase 22021-01-04
Active Not RecruitingA Study of Inebilizumab Efficacy and Safety in IgG4- Related Disease
IgG4 Related Disease
Phase 32020-12-04
CompletedStudy of Multiple Candidate Agents for the Treatment of COVID-19 in Hospitalized Patients
COVID-19
Phase 32020-11-24
CompletedA Study to Investigate ABP 654 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis
Plaque Psoriasis
Phase 32020-11-11
CompletedBiomarker and Genetic Predictors of Erenumab Treatment Response
Migraine
Phase 42020-10-26
Active Not RecruitingMyasthenia Gravis Inebilizumab Trial
Myasthenia Gravis
Phase 32020-10-15
CompletedInfusion Duration Study To Assess Tolerability of Pegloticase Administered With a Shorter Infusion Duration in
Chronic Uncontrolled Gout, Gout, Uncontrolled Gout
Phase 42020-10-02
CompletedBlinatumomab in Combination With AMG 404 for the Treatment of Adults With Relapsed or Refractory B Cell Precur
Acute Lymphoblastic Leukemia
Phase 12020-10-02
TerminatedStudy of AMG 330 in Combination With Pembrolizumab in Adult With Relapsed or Refractory Acute Myeloid Leukemia
Relapsed or Refractory Acute Myeloid Leukemia
Phase 12020-09-29
CompletedA Study of TEPEZZA Subcutaneous Administration in Healthy Adults
Bioavailability, Bioequivalence
Phase 12020-09-22
CompletedStudy of AMG 256 in Adult Subjects With Advanced Solid Tumors
Advanced Solid Tumors
Phase 12020-09-15
CompletedErenumab - Comprehensive Assessment of Efficacy in (High-Frequency) Episodic Migraine
Migraine
Phase 42020-09-15
CompletedSingle and Multiple Ascending Dose Study of AMG 133 in Participants With Obesity
Obesity
Phase 12020-08-07
CompletedStudy of Early Relapsed, Lenalidomide-refractory Subjects Eligible for Carfilzomib Triplet
Relapsed or Refractory Multiple Myeloma
Phase 22020-08-06
CompletedOlpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction - DOSE Finding Study
Cardiovascular Disease
Phase 22020-07-28
CompletedA Study to Evaluate the Impact of Acid-reducing Agents on the Pharmacokinetics (PK) of AMG 510 in Healthy Part
Healthy Participants
Phase 12020-07-17
TerminatedStudy of AMG 910 in Subjects With CLDN18.2-Positive Gastric and Gastroesophageal Junction Adenocarcinoma
Gastric and Gastroesophageal Junction Adenocarcinoma
Phase 12020-06-29
CompletedA Study to Understand Effectiveness and Safety of ABP 938 Compared to Aflibercept (Eylea®) in Patients Sufferi
Neovascular (Wet) Age-related Macular Degeneration (AMD)
Phase 32020-06-22
Active Not RecruitingStudy to Compare AMG 510 "Proposed INN Sotorasib" With Docetaxel in Non Small Cell Lung Cancer (NSCLC) (CodeBr
KRAS p, G12c Mutated /Advanced Metastatic NSCLC
Phase 32020-06-04
CompletedAMG 510 Ethnic Sensitivity Study (CodeBreaK 105).
Advanced/Metastatic Solid Tumors With KRAS p.G12C Mutation
Phase 12020-04-28
CompletedA Study of the Absorption, Metabolism, and Excretion of [14C]-AMG 510 Following a Single Oral Dose in Healthy
Healthy Subjects
Phase 12020-03-11
CompletedA Study to Evaluate the Relative Bioavailability of AMG 510 Administered as Tablets and as a Water Dispersion
Healthy Participants
Phase 12020-03-06
TerminatedHeart Failure Study to Evaluate Vital Signs and Overcome Low Use of Guideline-Directed Therapy by Remote Monit
Heart Failure
N/A2020-03-06
RecruitingStudy of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer
Prostate Cancer
Phase 12020-03-04
Active Not RecruitingStudy of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Non-small Cell Lung Canc
Chemotherapy-induced Thrombocytopenia
Phase 32020-02-26
CompletedEfficacy and Safety of AMG 570 in Subjects With Active Systemic Lupus Erythematosus (SLE)
Systemic Lupus Erythematosus (SLE)
Phase 22020-02-19
CompletedTalimogene Laherparepvec With Pembrolizumab in Melanoma Following Progression on Prior Anti-PD-1 Based Therapy
Melanoma
Phase 22020-01-22
TerminatedStudy of AMG 199 in Subjects With MUC17-Positive Solid Tumors Including Gastric, Gastroesophageal Junction, Co
MUC17-positive Solid Tumors
Phase 12020-01-20
CompletedStudy to Evaluate the Drug-drug Interaction Effect of Omeprazole on the Pharmacokinetics (PK) of AMG 510 in He
Healthy Participants
Phase 12020-01-06
WithdrawnSafety and Tolerability of Inebilizumab, VIB4920, or the Combination in Highly Sensitized Candidates Awaiting
Highly Sensitized Patients on Waiting List for Kidney Transplantation
Phase 22019-12-27
RecruitingA Phase 3 Study of Etelcalcetide in Children With Secondary Hyperparathyroidism Receiving Hemodialysis
Secondary Hyperparathyroidism
Phase 32019-12-20
CompletedA Long-term Extension Study of Apremilast (CC-10004) in Pediatric Subjects From 6 Through 17 Years of Age With
Psoriasis
Phase 32019-12-20
Active Not RecruitingSotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101)
Advanced Solid Tumors, Kirsten Rat Sarcoma (KRAS) pG12C Mutation
Phase 12019-12-17
TerminatedSingle and Multiple Ascending Dose Study of AMG 171 in Subjects With Obesity
Obesity
Phase 12019-12-13
CompletedA Study to Evaluate the Safety and Efficacy of VIB4920 in Participants With Rheumatoid Arthritis
Rheumatoid Arthritis
Phase 22019-12-09
CompletedA Study to Evaluate the Efficacy and Safety of VIB4920 in Participants With Sjögren's Syndrome
Sjögren's Syndrome
Phase 22019-12-09
TerminatedThe Cardiovascular Multi-dimensional Observational Investigation of the Use of PCSK9 Inhibitors (cvMOBIUS)
ASCVD
2019-12-06
TerminatedEffect of Erenumab-aooe on Disability and Work Productivity in Employed Subjects With Episodic Migraine
Migraine
Phase 42019-12-04
CompletedA Study to Evaluate the Drug-drug Interaction Effect of Itraconazole on the Pharmacokinetics (PK) of AMG 510 i
Healthy Participants
Phase 12019-12-03
CompletedA Study to Assess the Effect of Food on the Pharmacokinetics (PK) of AMG 510 in Healthy Participants
Healthy Participants
Phase 12019-11-14
CompletedStudy to Evaluate the Drug-drug Interactions Between Metformin and AMG 510 in Healthy Participants
Healthy Volunteers
Phase 12019-11-13
CompletedA Study to Assess the Effect of Avacopan at Therapeutic and Supratherapeutic Doses on the QT/QTc Interval in H
Electrocardiography
Phase 12019-11-08
CompletedA Study to Evaluate the Drug-drug Interaction Effect of Rifampin on the Pharmacokinetics of AMG 510 in Healthy
Healthy Participants
Phase 12019-11-05
CompletedStudy to Evaluate the Effect of AMG 510 on the Pharmacokinetics (PK) of Digoxin in Healthy Participants
Healthy Participants
Phase 12019-11-05
CompletedA Study to Evaluate the Safety and Efficacy of Dual Costimulation Blockade With VIB4920 and Belatacept for Pro
Allografts, Rejection; Transplant, Kidney, Transplant Rejection
Phase 22019-10-30
CompletedA Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in Japanese Subjects With Palmoplantar Pu
Palmoplantaris Pustulosis
Phase 22019-10-16
CompletedA Study to Evaluate the Efficacy and Safety of Erenumab in Adults With Medication Overuse Headache
Migraine Headache
Phase 42019-10-07
CompletedStudy of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Gastrointestinal, Pancre
Chemotherapy-induced Thrombocytopenia
Phase 32019-09-30
CompletedStudy to Evaluate Safety Tolerability & Efficacy of Kyprolis (Carfilzomib) in Relapsed or Refractory Multiple
Relapsed Refractory Multiple Myeloma
Phase 42019-09-16
CompletedStudy of Pegloticase in Participants With Uncontrolled Gout Who Have Had a Kidney Transplant
Uncontrolled Gout, Kidney Transplant
Phase 42019-09-09
CompletedEfficacy and Safety of Erenumab in Pediatric Subjects With Chronic Migraine
Migraine
Phase 32019-09-05
CompletedA Study to Evaluate the Safety, Tolerability Pharmacokinetics, and Pharmacodynamics of a New Spray Dried Dispe
Healthy Volunteers
Phase 12019-08-28
CompletedA Study to Describe the Characteristics of Patients Treated With Apremilast for Plaque Psoriasis in Italian Ro
Plaque Psoriasis
2019-07-22
Active Not RecruitingEfficacy and Safety of Erenumab in Pediatric Participants With Episodic Migraine
Migraine
Phase 32019-07-19
CompletedA Phase 3B, Open-label, Single-arm Study of the Efficacy and Safety of Apremilast, in Subjects With Plaque Pso
Plaque Psoriasis
Phase 32019-06-17
CompletedStudy of KRYSTEXXA® (Pegloticase) Plus Methotrexate in Participants With Uncontrolled Gout
Gout
Phase 42019-06-13
CompletedEffect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke
Coronary Heart Disease (CHD)
Phase 32019-06-11
CompletedStudy of Sustained Benefit of AMG334 in Adult Episodic Migraine Patients
Episodic Migraine
Phase 42019-05-15
TerminatedSafety and Efficacy of Evolocumab in Addition to Optimal Stable Background Statin Therapy in Chinese Participa
Primary Hypercholesterolemia, Mixed Dyslipidemia
Phase 32019-05-09
CompletedA Study Comparing Once-weekly vs Twice-weekly Carfilzomib in Combination With Lenalidomide and Dexamethasone i
Relapsed or Refractory Multiple Myeloma
Phase 32019-05-08
RecruitingA Trial of Etelcalcetide in Pediatric Participants With Secondary Hyperparathyroidism and Chronic Kidney Disea
Secondary Hyperparathyroidism, Chronic Kidney Disease
Phase 32019-04-29
CompletedA Controlled Trial of Erenumab in Migraine Prevention
Migraine
Phase 32019-04-12
CompletedA Study of the Impact of Apremilast (CC-10004) on Quality of Life, Efficacy, and Safety in Adults With Manifes
Psoriasis
Phase 42019-03-28
TerminatedA Dose Ranging Placebo-Controlled Double-Blind Study to Evaluate the Safety and Efficacy of Tezepelumab in Ato
Atopic Dermatitis
Phase 22019-03-15
CompletedApremilast as a Direct Treatment for Mild-to-moderate Plaque Psoriasis Versus Placebo: an Analysis of Clinical
Psoriasis
Phase 32019-03-11
CompletedAMG 404 in Patients With Advanced Solid Tumors
Advanced Solid Tumors
Phase 12019-03-05
TerminatedAssessment of AMG 420 in Subjects With Relapsed and/or Refractory Multiple Myeloma
Relapsed and/or Refractory Multiple Myeloma
Phase 12019-03-04
CompletedAn Efficacy and Safety Study of Apremilast (CC-10004) in Subjects With Moderate to Severe Genital Psoriasis
Psoriasis
Phase 32019-02-11
CompletedA Study to Evaluate the Use of Apremilast in Patients With Psoriatic Arthritis, Naïve to Biological Treatment
Arthritis, Psoriatic
2019-02-06
CompletedA Study to Evaluate the Impact of Apremilast on Magnetic Resonance Imaging (MRI) Outcomes in Adults With Psori
Psoriatic Arthritis
Phase 42019-02-06
TerminatedSafety, Tolerability, Pharmacokinetics, and Efficacy of Acapatamab in Subjects With mCRPC
Metastatic Castration-resistant Prostate Cancer, Prostate Cancer
Phase 12019-02-05
CompletedA Study to Evaluate the Pharmacokinetics, Safety and Tolerability of AMG 592 in Healthy Japanese Participants
Chronic Graft-versus-Host Disease (cGVHD)
Phase 12019-01-29
CompletedA Study Evaluating the Efficacy and Safety of ABP 959 Compared With Eculizumab in Adult Participants With PNH
Paroxysmal Nocturnal Hemoglobinuria
Phase 32019-01-22
CompletedEfficacy, Safety, and Tolerability Study of Apremilast to Treat Early Oligoarticular Psoriatic Arthritis.
Arthritis, Psoriatic
Phase 42018-12-31
CompletedEvaluation of Safety and Efficacy of Avacopan in Subjects With Moderate to Severe Hidradenitis Suppurativa (AU
Hidradenitis Suppurativa, Acne Inversa
Phase 22018-12-21
CompletedEfficacy and Safety Study of Apremilast (CC-10004) in Pediatric Subjects From 6 Through 17 Years of Age With M
Psoriasis
Phase 32018-12-19
CompletedA Study to Evaluate VIB7734 in Participants With Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythemat
Systemic Lupus Erythematosus, Cutaneous Lupus Erythematosus, Sjogren's Syndrome
Phase 12018-12-13
CompletedMultiple Ascending Dose Study of AMG 598 in Adults With Obesity
Obesity
Phase 12018-11-26
CompletedImaging of Coronary Plaques in Participants Treated With Evolocumab
Coronary Artery Disease (CAD)
Phase 32018-11-19
WithdrawnAn Interventional Study to Evaluate the Effect of Ivabradine on Exercise Capacity in Heart Transplant Recipien
Heart Transplantation, Elevated Resting Heart Rate
Phase 32018-11-02
TerminatedStudy to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMG 562 in Subjects With r/r Dif
Diffuse Large B-cell Lymphoma(DLBCL), Mantle Cell Lymphoma (MCL), Follicular Lymphoma (FL)
Phase 12018-10-29
TerminatedA Study of CCX140-B in Subjects With Primary FSGS and Nephrotic Syndrome
Focal Segmental Glomerulosclerosis
Phase 22018-10-01
CompletedStudy of Pegloticase (KRYSTEXXA®) Plus Methotrexate in Patients With Uncontrolled Gout
Gout
Phase 42018-09-26
CompletedA Study to Assess Benefits of Apremilast in Patients With Moderate to Severe Chronic Plaque Psoriasis Followed
Psoriasis
2018-09-25
TerminatedSafety, Tolerability, PK, PD, and Efficacy of AMG 427 in Subjects With Relapsed/Refractory Acute Myeloid Leuke
Relapsed/Refractory Acute Myeloid Leukemia (AML)
Phase 12018-09-14
SuspendedA Phase 1 Study Evaluating the Safety, Tolerability and Efficacy of AMG 119 in Subjects With RR SCLC
Small Cell Lung Cancer
Phase 12018-09-10
Active Not RecruitingA Phase 1/2, Study Evaluating the Safety, Tolerability, PK, and Efficacy of Sotorasib (AMG 510) in Subjects Wi
KRAS p.G12C Mutant Advanced Solid Tumors
Phase 1 / Phase 22018-08-27
TerminatedSafety, Tolerability, Pharmacokinetics and Efficacy of AMG 397 in Subjects With Selected Relapsed or Refractor
Multiple Myeloma, Acute Myeloid Leukemia, Non-Hodgkins Lymphoma
Phase 12018-08-17
TerminatedA Phase1 Study of VIB9600
Safety Issues
Phase 12018-08-14
CompletedSafety and Tolerability of Repatha® (Evolocumab) in Indian Participants With Homozygous Familial Hypercholeste
Homozygous Familial Hypercholesterolemia HoFH
Phase 42018-08-04
CompletedStudy to Evaluate the Real-World Effectiveness, Safety and Tolerability of Treatment With Apremilast in Psoria
Arthritis, Psoriatic
2018-07-31
CompletedSafety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of AMG 890 in Subjects With Elevated Plasma
Cardiovascular Disease
Phase 12018-07-30
TerminatedOpen-label Extension of Study 20130173 of Denosumab in Children and Young Adults With Osteogenesis Imperfecta
Osteogenesis Imperfecta (OI)
Phase 32018-07-26
TerminatedA Study of Carfilzomib Plus Dexamethasone in Adults With Relapsed or Refractory Multiple Myeloma at US Communi
Relapsed or Refractory Multiple Myeloma
Phase 22018-07-05
CompletedStudy to Evaluate the Benefits for the Patient Associated With the Treatment of Plaque Psoriasis With Apremila
Psoriasis
2018-06-12
TerminatedEffect of Blinatumomab on Minimal Residual Disease (MRD) in Diffuse Large B-Cell Lymphoma (DLBCL) Subjects Pos
High-risk Diffuse Large B-cell Lymphoma
Phase 22018-05-23
TerminatedSafety and Efficacy of Efavaleukin Alfa in Subjects With Active Rheumatoid Arthritis
Rheumatoid Arthritis RA
Phase 1 / Phase 22018-05-22
CompletedA Study of CCX140-B in Subjects With FSGS
FSGS, Focal Segmental Glomerulosclerosis, Glomerulosclerosis
Phase 22018-05-17
CompletedHead-to-Head Study of Etelcalcetide and Cinacalcet in Asian Hemodialysis Patients With Secondary Hyperparathyr
Secondary Hyperparathyroidism, Chronic Kidney Disease
Phase 32018-05-15
CompletedSafety and Efficiency of Denosumab in Pediatric Subjects With Glucocorticoid-induced Osteoporosis
Evaluate the Safety and Efficacy of Denosumab in Pediatric Subjects With, Glucocorticoid-induced Osteoporosis
Phase 32018-05-07
CompletedAMG 334 20160172 Pediatric Migraine PK Study.
Migraine
Phase 12018-05-04
TerminatedSafety and Efficacy of Efavaleukin Alfa in Subjects With Steroid Refractory Chronic Graft Versus Host Disease
Chronic Graft Versus Host Disease cGVHD
Phase 1 / Phase 22018-04-27
TerminatedStudy of AMG 596 in Patients With EGFRvIII Positive Glioblastoma
Glioblastoma or Malignant Glioma
Phase 12018-04-18
CompletedA Study to Evaluate the Pharmacokinetics of Avacopan (CCX168) in Participants With Mild or Moderate Hepatic Im
Hepatic Impairment
Phase 12018-04-17
CompletedTreatment of Graves' Orbitopathy to Reduce Proptosis With Teprotumumab Infusions in an Open-Label Clinical Ext
Thyroid Eye Disease
Phase 32018-04-16
CompletedSafety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Efavaleukin Alfa in Participan
Systemic Lupus Erythematosus
Phase 12018-04-10
CompletedStudy of Talimogene Laherparepvec With Atezolizumab for Triple Negative Breast Cancer and Colorectal Cancer Wi
Metastatic Triple Negative Breast Cancer, Metastatic Colorectal Cancer
Phase 12018-03-19
CompletedStudy Investigating the Safety and Efficacy of Blinatumomab in Combination With Pembrolizumab in Adults With R
Relapsed or Refractory Diffuse Large B Cell Lymphoma (DLBCL)
Phase 12018-03-16
CompletedA Phase 1 Study to Evaluate PK, Safety and Tolerability of AMG 416
Secondary Hyperparathyroidism
Phase 12018-03-01
CompletedStudy of Glycerol Phenylbutyrate & Sodium Phenylbutyrate in Phenylbutyrate Naïve Patients With Urea Cycle Diso
Urea Cycle Disorder
Phase 42018-02-20
CompletedA Comparison of Subject-administered Romosozumab With Healthcare Provider-administered Romosozumab for Osteopo
Post-Menopausal Osteoporosis
Phase 32018-02-06
WithdrawnStudy of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Lymphoma.
Chemotherapy-induced Thrombocytopenia
Phase 32018-01-27
Active Not RecruitingStudy Evaluating Safety, Tolerability and Pharmacokinetics (PK) of Tarlatamab in Adults With Small Cell Lung C
Small Cell Lung Carcinoma
Phase 12017-12-26
CompletedStudy to Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 986 Administered Orally to Healthy Volu
Heart Failure
Phase 12017-12-12
CompletedLong-term Safety Follow-up of Subjects With Giant Cell Tumor of Bone Treated With Denosumab in Study 20062004
Giant Cell Tumor of Bone
Phase 42017-11-13
TerminatedA Study to Assess AMG 701 Montherapy, or in Combination With Pomalidomide, With or Without, Dexamethasone in S
Relapsed/Refractory Multiple Myeloma
Phase 12017-11-13
CompletedA Study of CCX168 in Japanese and Caucasian Healthy Adult Males
Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis
Phase 12017-10-23
CompletedEfficacy and Safety of the BiTE Antibody Blinatumomab in Chinese Adult Subjects With Relapsed/Refractory B-pre
Acute Lymphoblastic Leukemia
Phase 32017-10-18
CompletedTreatment of Graves' Orbitopathy (Thyroid Eye Disease) to Reduce Proptosis With Teprotumumab Infusions in a Ra
Thyroid Eye Disease, Graves' Orbitopathy
Phase 32017-10-04
CompletedControlled Trial Evaluating Avacopan in C3 Glomerulopathy
C3 Glomerulopathy (C3G)
Phase 22017-09-29
CompletedA Study of Ivabradine in African-American/ Black Subjects With Heart Failure and Left Ventricular Systolic Dys
Heart Failure (HF)
Phase 42017-09-28
CompletedA Phase 1b Open-Label Study Investigating the Safety and Pharmacokinetics of Administration of Subcutaneous Bl
Non-Hodgkin's Lymphoma
Phase 12017-09-18
TerminatedStudy of Emerfetamab (AMG 673) in Adults With Relapsed/Refractory Acute Myeloid Leukemia (AML)
Acute Myeloid Leukemia
EARLY_Phase 12017-09-07
CompletedStudy to Evaluate the Efficacy and Safety of AMG 301 in Migraine Prevention
Chronic Migraine or Episodic Migraine
Phase 22017-09-06
CompletedPost-Marketing Surveillance Study of OTEZLA
Psoriasis
2017-09-05
CompletedStudy of Talimogene Laherparepvec In Children With Advanced Non CNS Tumors
Advanced Non CNS Tumors
Phase 12017-08-16
CompletedMultiple Ascending Doses of Rozibafusp Alfa (AMG 570) in Adults With Rheumatoid Arthritis
Rheumatoid Arthritis
Phase 12017-08-14
CompletedPostmarketing Prospective Study of Melanoma Patients Treated With IMLYGIC® to Characterize Risk of Herpetic In
Melanoma, Herpetic Infection
2017-08-10
CompletedStudy of Carfilzomib, Daratumumab and Dexamethasone for Patients With Relapsed and/or Refractory Multiple Myel
Relapsed Multiple Myeloma, Refractory Multiple Myeloma
Phase 32017-06-13
CompletedA Study Evaluating Safety and Pharmacokinetics of FPA144 in Japanese Patients With Advanced Gastric or Gastroe
Gastric or Gastroesophageal Cancer
Phase 12017-06-12
CompletedSafety, Tolerability and Efficacy on Low Density Lipoprotein Cholesterol (LDL-C) of Evolocumab in Participants
Subjects With Hyperlipidemia, Dyslipidemia and HIV Infection
Phase 32017-05-22
CompletedA Study of the Efficacy and Safety of Apremilast (CC-10004) in Subjects With Moderate to Severe Plaque Psorias
Psoriasis
Phase 32017-05-16
CompletedAMG 529 First in Human Study
Cardiovascular
Phase 12017-05-15
CompletedA Study of the Real-life Management of Psoriatic Arthritis Patients Treated With Otezla® (Apremilast) in Belgi
Arthritis, Psoriatic
2017-04-21
CompletedA Study of the Real-life Management of Psoriasis Patients Treated With Otezla® (Apremilast) in Belgium
Psoriasis
2017-04-06
CompletedCarfilzomib in Combination With Dexamethasone (Kd) in Chinese Patients With Relapsed & Refractory Multiple Mye
Relapsed and Refractory Multiple Myeloma
Phase 32017-03-31
CompletedObservational Study of Blinatumomab
Blincyto Use in Routine Clinical Practice
2017-03-22
CompletedA Phase 3 Clinical Trial of CCX168 (Avacopan) in Patients With ANCA-Associated Vasculitis
ANCA-Associated Vasculitis
Phase 32017-03-15
CompletedA Single-dose Study in Paediatric Patients Aged 2 to Less Than 18 Years With Secondary Hyperparathyroidism (sH
Chronic Kidney Disease, Secondary Hyperparathyroidism
Phase 12017-03-14
CompletedReal-world Use of Carfilzomib Among Multiple Myeloma Patients in Europe
Multiple Myeloma
2017-03-14
CompletedSafety and Efficacy of Blinatumomab in Adults With Newly Diagnosed High-risk Diffuse Large B-Cell Lymphoma
High-risk Diffuse Large B-Cell Lymphoma
Phase 22017-03-13
TerminatedFourier Open-label Extension Study in Subjects With Clinically Evident Cardiovascular Disease in Selected Euro
Dyslipidemia
Phase 32017-03-13
CompletedStudy to Evaluate the Safety/ Efficacy of T-VEC in Japanese Subjects With Unresectable Stage IIIB-IV Malignant
Unresectable Stage IIIB-IV Malignant Melanoma
Phase 12017-03-07
CompletedA Study of Apremilast Use and Effectiveness in Patients With Psoriatic Arthritis in The Netherlands
Arthritis, Psoriatic
2017-03-06
CompletedAPremilast After FumaRic Acid Ester Treatment
Psoriasis
2017-01-26
CompletedStudy to Evaluate Safety and Efficacy of Blinatumomab in Subjects With Relapsed/Refractory (R/R) Aggressive B-
B-Cell Non Hodgkin Lymphoma
Phase 2 / Phase 32017-01-23
CompletedPhase 1b Study Evaluating OPomD in Relapsed or Refractory Multiple Myeloma
Relapsed or Refractory Multiple Myeloma
Phase 12017-01-17
CompletedA Safety and Efficacy Study to Evaluate Romosozumab (AMG 785) in South Korean Women With Osteoporosis
Postmenopausal Osteoporosis
Phase 32017-01-16
TerminatedStudy to Evaluate the Safety of Repatha® in Pregnancy
Hypercholesterolaemia, Pregnancy
2017-01-12
TerminatedEvolocumab Pregnancy Exposure Registry
Hypercholesterolemia; ASCVD; Pregnancy
2016-12-22
CompletedGetting to an Improved Understanding of Low-Density Lipoprotein Cholesterol and Dyslipidemia Management (GOULD
Medical Conditions to be Studied, Dyslipidemia, ASCVD Management
2016-12-06
CompletedStudy to Assess the Injection Site Pain Associated With a New Etanercept Formulation in Adults With Rheumatoid
Arthritis, Rheumatoid; Arthritis, Psoriatic
Phase 32016-11-29
CompletedStudy to Assess if ABP710 is Safe & Effective in Treating Moderate to Severe Rheumatoid Arthritis Compared to
Arthritis, Rheumatoid
Phase 32016-10-10
CompletedSafety, Tolerability and Efficacy of Evolocumab (AMG 145) in Children With Inherited Elevated Low-density Lipo
Familial Hypercholesterolemia
Phase 32016-09-10
CompletedFurther Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk Open-label Exten
Dyslipidemia
Phase 32016-09-02
CompletedA Phase 1 Study of MEDI7734 in Type I Interferon-Mediated Autoimmune Diseases
Dermatomyositis, Polymyositis, Sjogren's, SLE, SSc
Phase 12016-08-26
CompletedA Study to Evaluate the Pharmacokinetic Exposure of 2 Formulations of Apremilast in Healthy Adults
Healthy Volunteers
Phase 12016-08-17
TerminatedStudy to Evaluate the Safety and Tolerability of AMG 986 in Healthy Volunteers and Heart Failure Patients
Heart Failure, Healthy Volunteer
Phase 12016-08-12
CompletedA Study of Real-World Experience of Psoriasis Patients Treated With Apremilast in Clinical Dermatology Practic
Psoriasis
2016-06-30
CompletedAn Study of Patients With Ph- Chromosome-negative Relapsed or Refractory Acute Lymphoblastic Leukemia in the U
Relapsed/Refractory Acute Lymphoblastic Leukemia
2016-06-30
CompletedLong-Term Safety Extension Study of ACTIMMUNE® (Interferon γ-1b) in Children and Young Adults With Friedreich'
Friedreich's Ataxia
Phase 32016-06-28
CompletedLong Term Post Marketing Specified Drug Use Result Survey for Evolocumab in Japan
Hypercholesterolemia, Familial Hypercholesterolemia
2016-06-24
CompletedStudy to Evaluate the Pharmacokinetics of Single and Multiple Doses of Apremilast in Healthy Adult Male Korean
Pharmacokinetics
Phase 12016-06-22
TerminatedAMG 176 First in Human Trial in Participants With Relapsed or Refractory Multiple Myeloma and Participants Wit
Relapsed or Refractory Multiple Myeloma, Relapsed or Refractory Acute Myeloid Leukemia
Phase 12016-06-13
CompletedStudy to Assess if ABP798 is Safe & Effective in Treating Non Hodgkin Lymphoma Compared to Rituximab
Lymphoma, Non-Hodgkin
Phase 32016-05-25
CompletedStudy to Evaluate the Efficacy of Etanercept Treatment in Adults Who Failed Therapy With Apremilast
Plaque Psoriasis
Phase 42016-05-18
CompletedStudy to Assess if ABP 798 is Safe & Effective in Treating Moderate to Severe Rheumatoid Arthritis (RA) Compar
Arthritis, Rheumatoid
Phase 32016-05-17
CompletedEvaluation of Evolocumab (AMG 145) Efficacy in Diabetic Adults With Hypercholesterolemia/Mixed Dyslipidemia
Hypercholesterolemia, Mixed Dyslipidemia, Type 2 Diabetes
Phase 32016-05-17
CompletedA Phase 1b Study of MEDI4920 in Participants With Adult-onset Rheumatoid Arthritis
Adult Onset Rheumatoid Arthritis
Phase 12016-05-12
CompletedDetermination of RAS Mutation Status in Liquid Biopsies in Subjects With RAS Wild-type.PERSEIDA Study
RAS Wild Type mCRC
2016-05-06
CompletedChart Review of Repatha® in Subjects With Hyperlipidaemia
Hypercholesterolaemia
2016-05-04
CompletedEffects of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition on Arterial Wall Inflammation in P
Subjects With Hyperlipidemia, Dyslipidemia
Phase 32016-04-14
CompletedSafety and Efficacy of Evolocumab in Combination With Statin Therapy in Adults With Diabetes and Hyperlipidemi
Diabetes, Hyperlipidemia, Mixed Dyslipidemia
Phase 32016-04-14
CompletedStudy to Evaluate the Efficacy and Safety of AMG 714 in Adult Patients With Type II Refractory Celiac Disease
Type II Refractory Celiac Disease (RCD-II), In-situ Small Bowel T-cell Lymphoma
Phase 22016-04-13
CompletedA Study to Evaluate the Efficacy and Safety of AMG 714 in Adult Patients With Celiac Disease
Celiac Disease
Phase 22016-04-13
CompletedTalimogene Laherparepvec With Pembrolizumab for Recurrent Metastatic Squamous Cell Carcinoma of the Head and N
Carcinoma of the Head and Neck
Phase 12016-04-06
WithdrawnStudy to Evaluate Darbepoetin Alfa in Pediatric Subjects With Anemia Due to Chronic Kidney Disease
Anemia, Chronic Kidney Disease
Phase 12016-04-01
CompletedSingle Ascending Dose Study of AMG 570 in Healthy Subjects
Systemic Lupus Erythematosus
Phase 12016-03-28
CompletedTrial Assessing Efficacy, Safety and Tolerability of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inh
Heterozygous Familial Hypercholesterolemia
Phase 32016-03-24
CompletedGoal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects-4
Hypercholesterolemia
Phase 32016-02-27
CompletedObservational Study of Apremilast in Patients With Psoriasis in The Netherlands
Psoriasis
2016-02-22
CompletedStudy to Evaluate the Effect of Erenumab on Blood Pressure When Given Concomitantly With Subcutaneous Sumatrip
Healthy Subjects
Phase 12016-02-22
CompletedStudy of Apremilast Use in Patients With Psoriatic Arthritic in Practice Conditions
Arthritis, Psoriatic
2016-02-18
CompletedErenumab (AMG 334) Plus Combined Oral Contraceptive Drug Interaction Study in Healthy Females
Headache, Migraine
Phase 12016-02-12
CompletedTrial to Evaluate the Safety of Talimogene Laherparepvec Injected Into Tumors Alone and in Combination With Sy
Hepatocellular Carcinoma, Liver Metastases, Cutaneous or Subcutaneous Lymph Node
Phase 1 / Phase 22016-02-05
CompletedA Study in Healthy Volunteers to Evaluate the Drug-Drug Interaction Potential of CCX168 With Concomitant Medic
Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis
Phase 12016-01-14
CompletedA Safety and Efficacy Study to Evaluate AMG 334 in Migraine Prevention
Migraine
Phase 22016-01-06
CompletedStudy to Evaluate Bioavailability of Apremilast Oral Suspension Relative to Tablet and to Assess Effect of Foo
Healthy Volunteers
Phase 12016-01-05
CompletedObservationaL Study on the Qol of RAS Wild-type mCRC Patients Receiving Anti-EGFR MAbs + FOLFOX or FOLFIRI as
Metastatic Colorectal Cancer
2015-12-30
CompletedSafety, Tolerability and Efficacy of ACTIMMUNE® Dose Escalation in Friedreich's Ataxia Study
Friedreich's Ataxia
Phase 32015-12-25
CompletedBone Histomorphometry in Postmenopausal Men and Women With Osteoarthritis Undergoing Total Hip Replacement
Osteoporosis
Phase 42015-12-22
CompletedEvolocumab Compared to LDL-C Apheresis in Patients Receiving LDL-C Apheresis Prior to Study Enrollment
Hypercholesterolemia
Phase 32015-12-21
CompletedA Study in Healthy Volunteers to Evaluate the Pharmacokinetic Food Effect and Cardiac Safety of CCX168
Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis
Phase 12015-12-03
CompletedTreadmill Cardiovascular Safety Study of Erenumab (AMG 334)
Stable Angina
Phase 22015-11-23
CompletedA Phase 1 Study in Subjects With Relapsed or Refractory Multiple Myeloma
Multiple Myeloma
Phase 12015-11-20
CompletedTo Evaluate the Blockade of CGRP in Preventing PACAP-38 Induced Migraine-like Attacks With AMG 334 in Migraine
Migraine
Phase 12015-11-11
CompletedPhase 3 Trial of Blinatumomab vs Standard Chemotherapy in Pediatric Subjects With HIgh-Risk (HR) First Relapse
Leukemia, Acute Lymphoblastic
Phase 32015-11-10
CompletedA Study to Evaluate the Safety, Tolerability, Immunogenicity, Pharmacokinetics, and Pharmacodynamics of AMG 59
Chronic Graft-versus-host Disease (cGVHD)
Phase 12015-10-19
CompletedA Study of Safety, Tolerability and Pharmacokinetics of Apremilast (CC-10004) in Pediatric Subjects With Moder
Psoriasis
Phase 22015-10-13
CompletedOnce-weekly Versus Twice-weekly Carfilzomib in Combination With Dexamethasone in Adults With Relapsed and Refr
Multiple Myeloma
Phase 32015-09-09
TerminatedA Phase 1 Study of AMG 330 in Subjects With Myeloid Malignancies
Relapsed/Refractory AML, Minimal Residual Disease Positive AML, Myelodysplastic Syndrome
Phase 12015-08-31
CompletedA Study of Otezla® in Patients With Plaque Psoriasis Under Routine Conditions
Psoriasis
2015-08-03
CompletedMultiple Ascending Dose Study on Safety, Tolerability, and Pharmacokinetics of AMG 581 in Healthy Subjects or
Schizophrenia or Schizoaffective Disorder
Phase 12015-08-01
CompletedSingle-ascending Dose Study With a Food-Effect Cohort to Evaluate AMG 581
Schizophrenia or Schizoaffective Disorder
Phase 12015-08-01
CompletedStudy to Evaluate the Efficacy and Safety of Erenumab (AMG 334) Compared to Placebo in Migraine Prevention
Migraine
Phase 32015-07-20
CompletedStudy to Evaluate the Efficacy and Safety of Erenumab (AMG 334) in Migraine Prevention
Migraine
Phase 32015-07-17
TerminatedMulticenter,Single-arm Study to Evaluate Efficacy, Safety, & Pharmacokinetics of Denosumab in Children w/ OI
Osteogenesis Imperfecta
Phase 32015-06-24
CompletedCharacteristics and Management of Postmenopausal Women With Osteoporosis Treated With Prolia® in France
Post Menopausal Osteoporosis
2015-06-16
CompletedExtension Study of Cinacalcet for Treatment of Secondary Hyperparathyroidism (SHPT) in Pediatric Patients With
Secondary Hyperparathyroidism, Chronic Kidney Disease
Phase 32015-06-10
CompletedStudy of Blinatumomab in Japanese Patients With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia
Relapsed Refractory B Precursor Acute Lymphoblastic Leukemia
Phase 1 / Phase 22015-06-04
CompletedSafety, Tolerability and Efficacy of ACTIMMUNE® Dose Escalation in Friedreich's Ataxia
Friedreich's Ataxia
Phase 32015-06-01
TerminatedA Long-term Extension of Study RP103-MITO-001 (NCT02023866) to Assess Cysteamine Bitartrate Delayed-release Ca
Mitochondrial Diseases
Phase 22015-05-19
WithdrawnStudy of Efficacy and Safety of Brodalumab Compared With Placebo in Subjects With Axial Spondyloarthritis
Axial Spondyloarthritis
Phase 22015-05-01
CompletedPhase 1b Study of Weekly Carfilzomib in Combination With Lenalidomide and Dexamethasone in Subjects With Multi
Multiple Myeloma
Phase 12015-04-30
TerminatedSafety Study of AMG 228 to Treat Solid Tumors
Advanced Malignancy, Advanced Solid Tumors, Cancer
Phase 12015-04-21
CompletedA Phase 4 Study of Efficacy and Safety of Apremilast in Subjects With Moderate Plaque Psoriasis.
Parapsoriasis
Phase 42015-04-20
CompletedSingle-arm Trial to Evaluate the Role of the Immune Response to Talimogene Laherparepvec in Unresected Melanom
Unresected Stage IIIb to IVM1c Melanoma
Phase 22015-04-07
TerminatedStudy to Evaluate the Safety, Tolerability, and Action of AMG 357 in Females With Rheumatoid Arthritis
Rheumatoid Arthritis
Phase 12015-04-01
TerminatedEvaluate Effects of Personalized Patient Counselling for Enbrel® Therapy in Adults With Rheumatoid Arthritis
Persistence to Enbrel
Phase 42015-04-01
CompletedEvaluation of Two Epoetin Alfa Dosing Strategies in Subjects With Chronic Kidney Disease Receiving Hemodialysi
Renal Insufficiency, Chronic, Anemia, Renal Dialysis
Phase 42015-04-01
CompletedOpen-Label Study to Evaluate Safety and Efficacy of CCX168 in Subjects With IGA Nephropathy on Stable RAAS Blo
Immunoglobulin A Nephropathy
Phase 22015-03-27
CompletedEtanercept and Methotrexate in Combination or as Monotherapy in Psoriatic Arthritis
Psoriatic Arthritis
Phase 32015-03-03
CompletedStudy of Etanercept Monotherapy vs Methotrexate Monotherapy for Maintenance of Rheumatoid Arthritis Remission
Rheumatoid Arthritis
Phase 32015-02-20
CompletedStudy of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute
Acute Lymphoblastic Leukemia (ALL)
Phase 12015-02-16
CompletedClinical Trial to Evaluate Safety and Efficacy of CCX168 in ANCA-Associated Vasculitis
ANCA-associated Vasculitis
Phase 22015-02-04
CompletedEfficacy and Safety of Talimogene Laherparepvec Neoadjuvant Treatment Plus Surgery Versus Surgery Alone for Me
Completely Resectable Stage IIIB, IIIC, or IVM1a Melanoma
Phase 22015-02-03
CompletedPhase 1b Study of CCX872-B in Patients With Pancreatic Adenocarcinoma
Pancreatic Cancer
Phase 12015-02-01
CompletedEfficacy and Safety Study of Apremilast to Treat Active Ulcerative Colitis
Ulcerative Colitis
Phase 22015-01-08
CompletedStudy to Assess the Immunogenicity and Safety of Etanercept Produced Using a Modified Process in Patients With
Plaque Psoriasis
Phase 42015-01-01
CompletedA Study of the Safety, Efficacy and Pharmacokinetics of Glycerol Phenylbutyrate in Pediatric Subjects Under 2
Urea Cycle Disorder
Phase 42014-12-31
CompletedA Phase 3 Randomized, Double-blind Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in Subje
Behçet's Syndrome
Phase 32014-12-30
CompletedLong-term Study of Romiplostim in Thrombocytopenic Pediatric Patients With Immune Thrombocytopenia (ITP)
Immune Thrombocytopenia
Phase 32014-12-10
CompletedHistorical Data Analysis of Complete Remission in Children With R/R Acute Lymphoblastic Leukemia (ALL)
B-cell Precursor Acute Lymphoblastic Leukemia (ALL)
2014-12-09
TerminatedPembrolizumab With Talimogene Laherparepvec or Placebo in Unresected Melanoma
Melanoma
Phase 32014-12-08
WithdrawnPhase 1b/2 Study of Oprozomib in Combination With Sorafenib in Subjects With Advanced Hepatocellular Carcinoma
Advanced Hepatocellular Carcinoma
Phase 1 / Phase 22014-12-01
TerminatedA Phase 1 Study of AMG 211 in Participants With Advanced Gastrointestinal Cancer
GI Adenocarcinoma
Phase 12014-11-27
CompletedOpen-label Extension (OLE) Study to Assess Safety and Efficacy of Evolocumab
Hypercholesterolemia
Phase 32014-11-24
CompletedStudy to Determine the Pharmacokinetic (PK) Bioequivalence of ABP 501 and Adalimumab (Humira®) in Healthy Adul
Healthy Volunteers
Phase 12014-11-24
CompletedProspective Observational Study of 1st and 2nd Line Vectibix® Use in RAS-wt mCRC Pts to Evaluate Pattern of Us
Metastatic Colorectal Cancer
2014-11-21
TerminatedEfficacy and Safety of Cinacalcet in Pediatric Patients With Secondary Hyperparathyroidism (SHPT) and Chronic
Chronic Kidney Disease, Secondary Hyperparathyroidism
Phase 32014-11-07
CompletedA Non-Interventional Study of RAYOS in Adult Patients With Rheumatoid Arthritis
Rheumatoid Arthritis
2014-11-01
WithdrawnEvaluate Time Associated With the Preparation & Administration of Denosumab/Pamidronate in Patients With Solid
Solid Tumor, Metastatic Bone Disease
Phase 42014-11-01
CompletedA Study to Assess the Mass Balance Recovery (Absorption, Distribution, Metabolism and Excretion) of [14C]CCX16
Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis
Phase 12014-10-20
CompletedA Phase 1, Open-Label Study of Teprotumumab in Patients With Diabetic Macular Edema (DME)
Diabetic Macular Edema
Phase 12014-10-01
CompletedEvaluating PCSK9 Binding antiBody Influence oN coGnitive HeAlth in High cardiovascUlar Risk Subjects
Dyslipidemia
Phase 32014-09-10
CompletedEstimation Study to Assess the Effect of Severe Renal Impairment and End-stage Renal Disease Hemodialysis on t
Hyperlipidemia, Mixed Dyslipidemia
Phase 12014-08-19
TerminatedA Phase 1 Study of Oprozomib to Assess Food Effect, Drug-Drug Interaction With Midazolam, and Safety and Toler
Advanced Non-Central Nervous System (CNS) Malignancies
Phase 12014-08-01
TerminatedA Study of Oprozomib, Pomalidomide, and Dexamethasone in Adults With Primary Refractory or Relapsed and Refrac
Multiple Myeloma
Phase 12014-07-30
CompletedProspective Observational Study of Febrile Neutropenia (FN) and Pegfilgrastim Primary Prophylaxis in Breast Ca
Chemotherapy-induced Febrile Neutropenia
2014-07-18
CompletedEffects on Lipoprotein Metabolism From PCSK9 Inhibition Utilizing a Monoclonal Antibody
Primary Hyperlipidemia and Mixed Dyslipidemia
Phase 32014-07-08
TerminatedA Phase 3 Study of Rilotumumab (AMG 102) With Cisplatin and Capecitabine (CX) as First-line Therapy in Gastric
Gastric Cancer
Phase 32014-07-01
CompletedStudy of Patients With ITP Estimating the Proportion Administering Romiplostim Correctly After Receiving Home
Immune Thrombocytopenic Purpura
2014-07-01
CompletedA Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 282 in Healthy Sub
Chronic Rhinosinusitis With Nasal Polyps
Phase 12014-07-01
CompletedA Study to Assess the Long-term Safety and Efficacy of Erenumab (AMG 334) in Chronic Migraine Prevention.
Treatment for Prevention of Chronic Migraine
Phase 22014-06-30
CompletedA Study to Compare the Safety and Efficacy of Romosozumab (AMG 785) Versus Placebo in Men With Osteoporosis
Osteoporosis in Men
Phase 32014-06-16
CompletedDarbepoetin Alfa MDS Companion Protocol
Myelodysplastic Syndrome (MDS)
Phase 32014-06-12
CompletedObservational Study of Correction of Anaemia With Darbepoetin Alfa at QM Dosing Interval in Patients With CKD
Anaemia, Chronic Kidney Disease (CKD)
2014-06-01
CompletedEfficacy and Safety Study of Apremilast in Subjects With Moderate to Severe Atopic Dermatitis
Dermatitis, Atopic Dermatitis
Phase 22014-06-01
CompletedStudy of Haemodialysis Patients Switching From Aranesp to Biosimilar
Anaemia
2014-06-01
TerminatedPhase I, Double-Blind,Placebo, MAD Study to Evaluate the Safety, Tolerability, PK, and PD of AMG 333 in Health
Migraine
Phase 12014-05-01
CompletedA Double-blind Study to Assess the Efficacy and Safety of Denosumab Produced by Two Different Processes in Pos
Postmenopausal Osteoporosis
Phase 32014-05-01
CompletedOpen-Label, Dose-Escalating Study Assessing Safety, Tolerability, Efficacy, of RP103 in Mitochondrial Disease
Inherited Mitochondrial Disease, Including Leigh Syndrome
Phase 22014-05-01
CompletedA Phase 1/2 Study Evaluating AMG 337 in Asian Subjects
Stomach Neoplasms
Phase 1 / Phase 22014-04-15
CompletedSingle-arm Trial to Evaluate the Biodistribution and Shedding of Talimogene Laherparepvec
Melanoma
Phase 22014-04-07
CompletedEffect of Denosumab on Cellular Biomarkers in the Human Breast
Healthy Volunteer, Female, Breast
Phase 12014-04-01
CompletedLong-term Safety and Efficacy of ABP 501 in Subjects With Moderate to Severe Rheumatoid Arthritis
Arthritis, Rheumatoid
Phase 32014-04-01
CompletedExtension Study of Etelcalcetide for Treatment of Secondary Hyperparathyroidism in Patients With Chronic Kidne
Hyperparathyroidism, Secondary
Phase 32014-03-25
CompletedA Study to Evaluate the Efficacy and Safety of Erenumab (AMG 334) in Chronic Migraine Prevention
Treatment for Prevention of Chronic Migraine
Phase 22014-03-05
CompletedPharmacokinetics and Excretion of [¹⁴C]Etelcalcetide (AMG 416) in Patients With End Stage Renal Disease (ESRD)
Secondary Hyperparathyroidism in Patients With ESRD on Hemodialysis
Phase 12014-02-07
TerminatedPhase 2 Study of AMG 337 in MET Amplified Gastric/Esophageal Adenocarcinoma or Other Solid Tumors
Stomach Neoplasms
Phase 22014-02-01
CompletedBioequivalence Study of Denosumab CP4 Drug Product and Commercially Available Denosumab CP2 Drug Product
Healthy Volunteer
Phase 12014-02-01
CompletedStudy to Evaluate Pharmacokinetics of Prototype Modified-Release Formulations Of Apremilast in Healthy Men
Healthy Volunteers
Phase 12014-01-07
CompletedBlinatumomab in Adults With Relapsed/Refractory Philadelphia Positive B-precursor Acute Lymphoblastic Leukemia
Relapsed/Refractory Philadelphia Positive B-precursor ALL
Phase 22014-01-03
TerminatedBlinatumomab Versus Standard of Care Chemotherapy in Patients With Relapsed or Refractory Acute Lymphoblastic
Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia
Phase 32014-01-03
CompletedEstimation of Off-Label Use of XGEVA® (Denosumab) Using Population-Based Databases in Denmark
XGEVA Off-label Use
2014-01-01
CompletedStudy of the Pharmacokinetics and Safety of Carfilzomib in Patients With Multiple Myeloma and Renal Disease
Relapsed Multiple Myeloma, End-stage Renal Disease
Phase 12014-01-01
CompletedA Study of Oprozomib, Melphalan, and Prednisone in Transplant Ineligible Patients With Newly Diagnosed Multipl
Multiple Myeloma
Phase 1 / Phase 22014-01-01
CompletedDenosumab in Combination With Chemotherapy as First-line Treatment of Metastatic Non-small Cell Lung Cancer
Non-Small Cell Lung Cancer
Phase 22013-12-31
CompletedGoal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects-3
Hyperlipidemia
Phase 32013-12-10
CompletedA Randomized Phase 3 Study to Evaluate Two Formulations of Romosozumab in Postmenopausal Women With Osteoporos
Postmenopausal Osteoporosis
Phase 32013-12-03
CompletedEfficacy and Safety Study of ABP 215 Compared With Bevacizumab in Patients With Advanced Non-Small Cell Lung C
Non-small Cell Lung Cancer Metastatic
Phase 32013-11-11
CompletedPhase 1b/2 Study of Carfilzomib, Carboplatin, and Etoposide in Patients With Previously Untreated Extensive St
Extensive-Stage Small-Cell Lung Cancer
Phase 1 / Phase 22013-11-05
TerminatedOprozomib and Dexamethasone,in Combination With Lenalidomide or Oral Cyclophosphamide to Treat Newly Diagnosed
Multiple Myeloma
Phase 1 / Phase 22013-10-28
CompletedStudy to Compare Efficacy and Safety of ABP 501 and Adalimumab (HUMIRA®) in Adults With Moderate to Severe Pla
Psoriasis
Phase 32013-10-18
CompletedStudy of the Pharmacokinetics and Safety of Carfilzomib in Patients With Advanced Malignancies and Hepatic Imp
Solid Tumors, Hematologic Malignancies, Hepatic Impairment
Phase 12013-10-01
CompletedEfficacy and Safety Study of ABP 501 Compared to Adalimumab in Subjects With Moderate to Severe Rheumatoid Art
Arthritis, Rheumatoid
Phase 32013-10-01
CompletedSingle-Ascending Dose Study of AMG 333 in Healthy Subjects and Subjects With Migraines
Migraine
Phase 12013-10-01
CompletedStudy of Low-Density Lipoprotein Cholesterol (LDL-C) Reduction Using Evolocumab (AMG 145) in Japanese Patients
Hyperlipidemia or Mixed Dyslipidemia at High Risk for Cardiovascular Events
Phase 32013-10-01
CompletedHistorical Data Analysis of Hematological Remission and Survival in Adults With R/R Acute Lymphoblastic Leukem
Acute Lymphoblastic Leukemia
2013-10-01
TerminatedObservational Study That Will Collect Information on Patients With Urea Cycle Disorders (UCDs)
Urea Cycle Disorder
2013-09-25
CompletedSafety and Efficacy Study of Apremilast to Treat Psoriatic Arthritis
Psoriatic Arthritis
Phase 32013-09-04
CompletedRetrospective Analysis of Survival in Adult MRD Positive Acute Lymphoblastic Leukemia Patients
Acute Lymphoblastic Leukemia
2013-09-01
CompletedHead-to-Head Study of Etelcalcetide (AMG 416) and Cinacalcet
Secondary Hyperparathyroidism, Chronic Kidney Disease
Phase 32013-08-13
CompletedStudy to Assess the Impact on Calcium Levels When Hemodialysis Patients With Secondary Hyperparathyroidism (SH
Hyperparathyroidism, Secondary
Phase 32013-08-12
CompletedStudy to Evaluate the Efficacy and Safety of Erenumab (AMG 334) in Migraine Prevention
Migraine
Phase 22013-08-06
CompletedA First-in-Human, Double Blind, Single Dose Study in Healthy Subjects and Subjects With Mild Atopic Asthma.
Asthma
Phase 12013-08-01
CompletedA Multicenter, Open-label, Phase 1b Study of Carfilzomib, Cyclophosphamide and Dexamethasone in Newly Diagnose
Multiple Myeloma
Phase 12013-08-01
CompletedExtension Study of Etelcalcetide in the Treatment of Secondary Hyperparathyroidism (SHPT) in Patients With Chr
Hyperparathyroidism, Secondary
Phase 32013-07-31
CompletedStudy to Assess in Home Use of Evolocumab (AMG 145) Administration Using Either an Automated Mini-doser or a P
Primary Hypercholesterolemia, Mixed Dyslipidemia
Phase 32013-07-11
CompletedEfficacy and Safety Study of Two Doses of Apremilast (CC-10004) In Japanese Patients With Moderate-To-Severe P
Psoriasis, Psoriatic Arthritis, Psoriasis Arthropatica
Phase 22013-07-09
CompletedPhase 3 Study of Carfilzomib, Melphalan, Prednisone vs Bortezomib, Melphalan, Prednisone in Newly Diagnosed Mu
Multiple Myeloma
Phase 32013-07-08
TerminatedPhase 1b/2, Multicenter, Open-label Study of Oprozomib and Dexamethasone in Patients With Relapsed and/or Refr
Multiple Myeloma
Phase 1 / Phase 22013-07-02
CompletedTeprotumumab (RV 001) Treatment in Patients With Active Thyroid Eye Disease
Thyroid Associated Ophthalmopathies, Thyroid-Associated Ophthalmopathy
Phase 22013-07-01
CompletedStudy to Evaluate the Ability of Subjects With Rheumatoid Arthritis or Psoriatic Arthritis to Effectively Use
Rheumatoid Arthritis, Psoriatic Arthritis
Phase 32013-06-11
CompletedPreference Between Two Autoinjectors in Patients With Rheumatoid Arthritis and Plaque Psoriasis Treated With E
Rheumatoid Arthritis, Plaque Psoriasis
Phase 42013-06-05
CompletedStudy to Evaluate the Concentration of Denosumab in Seminal Fluid in Healthy Men After a Single Subcutaneous D
Healthy Volunteer
Phase 12013-06-01
TerminatedStudy of Efficacy and Safety of Brodalumab Compared With Placebo in Adults With Inadequately Controlled Asthma
Asthma
Phase 22013-05-22
CompletedStudy of Erenumab (AMG 334) in Women With Hot Flashes
Vasomotor Symptoms; Hot Flashes
Phase 12013-05-13
TerminatedEvaluating Etanercept Use in Patients With Moderate to Severe Rheumatoid Arthritis Who Have Lost Response to A
Moderate to Severe Rheumatoid Arthritis
Phase 42013-05-06
CompletedEfficacy and Safety Study of ABP 980 Compared With Trastuzumab in Women With HER2-positive Early Breast Cancer
Breast Cancer
Phase 32013-04-29
CompletedOpen-label Extension Study of Evolocumab (AMG 145) in Adults With Hyperlipidemia and Mixed Dyslipidemia
Hyperlipidemia and Mixed Dyslipidemia
Phase 32013-04-23
CompletedStudy of Romosozumab (AMG 785) Administered to Healthy Participants and Patients With Stage 4 Renal Impairment
Osteoporosis
Phase 12013-04-22
CompletedStudy to Assess In-home Use of Evolocumab (AMG 145) Using a Prefilled Syringe or a Prefilled Autoinjector/Pen
Primary Hypercholesterolemia, Mixed Dyslipidemia
Phase 32013-04-18
CompletedGLobal Assessment of Plaque reGression With a PCSK9 antibOdy as Measured by intraVascular Ultrasound
Hypercholesterolemia
Phase 32013-04-18
TerminatedStudy of South African Dialysis Patients
Chronic Kidney Disease, Receiving Dialysis
2013-04-01
CompletedEfficacy and Safety of Etelcalcetide (AMG 416) in the Treatment of Secondary Hyperparathyroidism (SHPT) in Pat
Hyperparathyroidism, Secondary
Phase 32013-03-12

Showing the 500 most recent trials.