Clinical Trials Directory

Trials / Completed

CompletedNCT05174065

Phase 3, Randomized Study of Apremilast in Japanese Participants With Palmoplantar Pustulosis (PPP)

A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Apremilast (AMG 407) in Japanese Subjects With Palmoplantar Pustulosis (PPP)

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
176 (actual)
Sponsor
Amgen · Industry
Sex
All
Age
18 Years – 99 Years
Healthy volunteers
Not accepted

Summary

The primary objective of the study is to evaluate the efficacy of apremilast (AMG 407) twice daily (BID) compared with placebo in participants with Palmoplantar Pustulosis (PPP).

Conditions

Interventions

TypeNameDescription
DRUGApremilastOral tablets
DRUGPlaceboOral tablets

Timeline

Start date
2022-03-08
Primary completion
2023-08-19
Completion
2024-06-01
First posted
2021-12-30
Last updated
2025-04-09
Results posted
2025-04-09

Locations

40 sites across 1 country: Japan

Regulatory

Source: ClinicalTrials.gov record NCT05174065. Inclusion in this directory is not an endorsement.