Clinical Trials Directory

Trials / Completed

CompletedNCT05325866

A Study Evaluating Bemarituzumab in Solid Tumors With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression

A Phase 1b/2, Multicenter, Open-label Basket Study Evaluating the Safety and Efficacy of Bemarituzumab Monotherapy in Solid Tumors With FGFR2b Overexpression (FORTITUDE-301)

Status
Completed
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
260 (actual)
Sponsor
Amgen · Industry
Sex
All
Age
18 Years – 99 Years
Healthy volunteers
Not accepted

Summary

The primary objectives of this study are to observe the safety and tolerability of bemarituzumab and to evaluate preliminary antitumor activity.

Conditions

Interventions

TypeNameDescription
DRUGBemarituzumabIntravenous (IV) infusion.

Timeline

Start date
2022-09-23
Primary completion
2026-01-28
Completion
2026-01-28
First posted
2022-04-13
Last updated
2026-02-04

Locations

115 sites across 26 countries: United States, Argentina, Australia, Austria, Belgium, Brazil, Bulgaria, Canada, Czechia, Denmark, Finland, France, Greece, Hungary, Israel, Italy, Japan, Mexico, Netherlands, Poland, Portugal, Romania, South Korea, Spain, Switzerland, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT05325866. Inclusion in this directory is not an endorsement.

A Study Evaluating Bemarituzumab in Solid Tumors With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression (NCT05325866) · Clinical Trials Directory