Trials / Terminated
TerminatedNCT06910709
Single and Multiple Ascending Dose Study of AMG 378 in Healthy Participants
A Phase 1 Randomized, Double-blind, Placebo-controlled, Single and Multiple Ascending Dose and Food-effect Study to Evaluate the Safety, Tolerability, Pharmacokinetics of AMG 378 in Healthy Participants
- Status
- Terminated
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 48 (actual)
- Sponsor
- Amgen · Industry
- Sex
- All
- Age
- 18 Years – 55 Years
- Healthy volunteers
- Accepted
Summary
The main objective of the study is to assess the safety and tolerability of AMG 378 as single or multiple doses in healthy participants.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | AMG 378 | Oral tablet |
| DRUG | Placebo | Oral tablet |
Timeline
- Start date
- 2025-04-08
- Primary completion
- 2025-12-02
- Completion
- 2025-12-02
- First posted
- 2025-04-04
- Last updated
- 2026-04-02
Locations
2 sites across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT06910709. Inclusion in this directory is not an endorsement.