Clinical Trials Directory

Trials / Completed

CompletedNCT02304484

Open-label Extension (OLE) Study to Assess Safety and Efficacy of Evolocumab

A Multicenter, Open-label Extension (OLE) Study to Assess the Long-term Safety and Efficacy of Evolocumab

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
770 (actual)
Sponsor
Amgen · Industry
Sex
All
Age
18 Years – 99 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study was to characterize the safety and tolerability of long-term administration of evolocumab in adults with known coronary artery disease and hypercholesterolemia.

Conditions

Interventions

TypeNameDescription
BIOLOGICALEvolocumabAdministered by subcutaneous injection once a month

Timeline

Start date
2014-11-24
Primary completion
2018-03-09
Completion
2018-03-09
First posted
2014-12-02
Last updated
2019-03-19
Results posted
2019-03-19

Locations

126 sites across 29 countries: United States, Argentina, Australia, Belgium, Brazil, Canada, Chile, Czechia, France, Germany, Greece, Hungary, Iceland, Ireland, Israel, Italy, Malaysia, Mexico, Netherlands, Norway, Poland, Russia, South Africa, South Korea, Spain, Sweden, Switzerland, Taiwan, United Kingdom

Source: ClinicalTrials.gov record NCT02304484. Inclusion in this directory is not an endorsement.