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Active Not RecruitingNCT06987695

Efficacy and Safety of Maridebart Cafraglutide in Adult Participants in Japan Who Have Obesity Disease

A Phase 3 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Maridebart Cafraglutide in Adult Participants in Japan Who Have Obesity Disease (MARITIME 3-J)

Status
Active Not Recruiting
Phase
Phase 3
Study type
Interventional
Enrollment
279 (actual)
Sponsor
Amgen · Industry
Sex
All
Age
18 Years – 99 Years
Healthy volunteers
Not accepted

Summary

The primary objective of this study is to demonstrate that maridebart cafraglutide is superior to placebo for percent change in body weight and proportion of participants with ≥ 5% reduction in body weight.

Conditions

Interventions

TypeNameDescription
DRUGMaridebart cafraglutideMaridebart cafraglutide will be administered SC.
DRUGPlaceboPlacebo will be administered SC.

Timeline

Start date
2025-06-13
Primary completion
2027-04-27
Completion
2027-07-21
First posted
2025-05-23
Last updated
2025-12-17

Locations

30 sites across 1 country: Japan

Regulatory

Source: ClinicalTrials.gov record NCT06987695. Inclusion in this directory is not an endorsement.

Efficacy and Safety of Maridebart Cafraglutide in Adult Participants in Japan Who Have Obesity Disease (NCT06987695) · Clinical Trials Directory