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CompletedNCT03029234

Carfilzomib in Combination With Dexamethasone (Kd) in Chinese Patients With Relapsed & Refractory Multiple Myeloma

An Open-label, Single-arm, Phase 3 Study of Carfilzomib in Combination With Dexamethasone in Subjects With Relapsed and Refractory Multiple Myeloma in China

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
126 (actual)
Sponsor
Amgen · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the safety, tolerability and overall response rate of carfilzomib in combination with dexamethasone for the treatment of multiple myeloma in China.

Conditions

Interventions

TypeNameDescription
DRUGDexamethasone20 mg intravenous (IV) or oral dexamethasone on days 1, 2, 8, 9, 15, 16, 22, and 23 in 28-day cycles.
DRUGCarfilzomibInfusion of IV carfilzomib on days 1, 2, 8, 9, 15 and 16 in each 28-day cycle.

Timeline

Start date
2017-03-31
Primary completion
2018-11-05
Completion
2021-06-04
First posted
2017-01-24
Last updated
2022-05-25
Results posted
2019-11-21

Locations

17 sites across 1 country: China

Regulatory

Source: ClinicalTrials.gov record NCT03029234. Inclusion in this directory is not an endorsement.

Carfilzomib in Combination With Dexamethasone (Kd) in Chinese Patients With Relapsed & Refractory Multiple Myeloma (NCT03029234) · Clinical Trials Directory