Clinical Trials Directory

Trials / Recruiting

RecruitingNCT06321601

Study to Evaluate Avacopan in Combination With a Rituximab or Cyclophosphamide-containing Regimen, in Children From 6 Years to < 18 Years of Age With AAV.

A Phase 3, Open-label, Uncontrolled Single-arm Study to Evaluate the Efficacy, Pharmacokinetics, and Safety of Avacopan in Combination With a Rituximab or a Cyclophosphamide-containing Regimen in Children From 6 Years to < 18 Years of Age With Active ANCA-associated Vasculitis (AAV)

Status
Recruiting
Phase
Phase 3
Study type
Interventional
Enrollment
20 (estimated)
Sponsor
Amgen · Industry
Sex
All
Age
6 Years – 17 Years
Healthy volunteers
Not accepted

Summary

The main objective of this study is to explore the efficacy of avacopan in participants affected by AAV.

Conditions

Interventions

TypeNameDescription
DRUGAvacopanOral administration

Timeline

Start date
2024-10-22
Primary completion
2028-09-26
Completion
2028-09-26
First posted
2024-03-20
Last updated
2026-03-06

Locations

30 sites across 9 countries: United States, Belgium, Canada, Czechia, France, Hungary, Poland, Slovakia, Spain

Regulatory

Source: ClinicalTrials.gov record NCT06321601. Inclusion in this directory is not an endorsement.