Clinical Trials Directory

Trials / Completed

CompletedNCT03927144

Study of Sustained Benefit of AMG334 in Adult Episodic Migraine Patients

A 12-month Prospective, Randomized, Interventional, Global, Multi-center, Active-controlled Study Comparing Sustained Benefit of Two Treatment Paradigms (AMG334 qm vs. Oral Prophylactics) in Adult Episodic Migraine Patients

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
621 (actual)
Sponsor
Amgen · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to compare the sustained long-term benefit between two treatment paradigms of migraine prophylactic agents (erenumab versus a control arm of oral prophylactics) in episodic migraine patients who have previously failed 1 to 2 prophylactic migraine treatments.

Conditions

Interventions

TypeNameDescription
DRUGAMG334Subcutaneous Injection
DRUGOral ProphylacticSOC Oral Tablet/Capsule

Timeline

Start date
2019-05-15
Primary completion
2021-10-01
Completion
2022-09-30
First posted
2019-04-25
Last updated
2023-11-18
Results posted
2022-10-25

Locations

112 sites across 18 countries: United States, Argentina, Austria, Belgium, Czechia, Finland, France, Germany, Greece, Ireland, Israel, Italy, Netherlands, Poland, Portugal, Slovakia, Spain, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT03927144. Inclusion in this directory is not an endorsement.