Clinical Trials Directory

Trials / Completed

CompletedNCT01966003

Efficacy and Safety Study of ABP 215 Compared With Bevacizumab in Patients With Advanced Non-Small Cell Lung Cancer

A Randomized, Double-blind, Phase 3 Study Evaluating the Efficacy and Safety of ABP 215 Compared With Bevacizumab in Subjects With Advanced Non-Small Cell Lung Cancer

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
642 (actual)
Sponsor
Amgen · Industry
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

The purpose of this research study is to compare the effectiveness and safety of ABP 215 against bevacizumab in men and women with advanced non-small cell lung cancer.

Conditions

Interventions

TypeNameDescription
DRUGCarboplatinAdministered at an area under the concentration-time curve (AUC) 6 by IV infusion Q3W
DRUGPaclitaxelAdministered 200 mg/m² IV Q3W
DRUGABP 215Administered 15 mg/kg Q3W by IV infusion
DRUGBevacizumabAdministered 15 mg/kg Q3W by IV infusion

Timeline

Start date
2013-11-11
Primary completion
2015-07-23
Completion
2015-07-23
First posted
2013-10-21
Last updated
2017-10-19
Results posted
2017-10-19

Locations

4 sites across 3 countries: United States, Australia, Bulgaria

Source: ClinicalTrials.gov record NCT01966003. Inclusion in this directory is not an endorsement.