Clinical Trials Directory

Trials / Completed

CompletedNCT02575833

Treadmill Cardiovascular Safety Study of Erenumab (AMG 334)

A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effect of AMG 334 on Exercise Time During a Treadmill Test in Subjects With Stable Angina

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
89 (actual)
Sponsor
Amgen · Industry
Sex
All
Age
18 Years – 85 Years
Healthy volunteers
Not accepted

Summary

A phase 2a, multicenter, randomized, double-blind, placebo-controlled study in adults with stable angina to evaluate the effect of erenumab (AMG 334) compared to placebo on exercise time during an exercise treadmill test.

Conditions

Interventions

TypeNameDescription
DRUGErenumabA single dose of erenumab 140 mg infused over approximately 60 minutes.
DRUGPlaceboA single dose of a matching volume of placebo infused over approximately 60 minutes.

Timeline

Start date
2015-11-23
Primary completion
2017-01-23
Completion
2017-04-13
First posted
2015-10-15
Last updated
2018-08-24
Results posted
2018-07-05

Locations

33 sites across 10 countries: United States, Bulgaria, Czechia, Latvia, New Zealand, Poland, Romania, Slovakia, South Africa, Switzerland

Source: ClinicalTrials.gov record NCT02575833. Inclusion in this directory is not an endorsement.