Clinical Trials Directory

Trials / Completed

CompletedNCT02191150

Study of Haemodialysis Patients Switching From Aranesp to Biosimilar

Retrospective Study of Stable Haemodialysis Patients Switched From Darbepoetin Alfa to Epoetin Alfa Biosimilar

Status
Completed
Phase
Study type
Observational
Enrollment
272 (actual)
Sponsor
Amgen · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The study will obtain data to show insight into clinical outcomes of patients switching from Darbepoetin Alfa to a epoetin alfa biosimilar.

Detailed description

Biosimilars were approved in 2007 by the EMA in EU and in 2010 by the TGA in Australia. This study will look at the retrospective data of patients that have switched from Darbepoetin Alfa to an approved epoetin alfa biosimilar. Data will be collected for the 26 week period prior to switch and a 26 week period post switch to a biosimilar. Data to be collected includes haemoglobin measurements, dose requirements, iron use, any transfusions, hospitalisations and other lab values including TSAT, Ferritin and albumin. Data from the study will be published.

Conditions

Timeline

Start date
2014-06-01
Primary completion
2015-04-01
Completion
2015-05-01
First posted
2014-07-16
Last updated
2016-02-08

Locations

23 sites across 7 countries: Australia, Bulgaria, Germany, Greece, Italy, Poland, Spain

Source: ClinicalTrials.gov record NCT02191150. Inclusion in this directory is not an endorsement.